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Volumn 8, Issue 10, 2013, Pages

Involvement of miRNAs in the Differentiation of Human Glioblastoma Multiforme Stem-Like Cells

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 106A; MICRORNA 21; MICRORNA 221; MICRORNA 222; MICRORNA 29A; MICRORNA 29B; MICRORNA 93; UNCLASSIFIED DRUG;

EID: 84885392997     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077098     Document Type: Article
Times cited : (63)

References (48)
  • 2
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • 10.1056/NEJMoa043330
    • Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996. doi:10.1056/NEJMoa043330. PubMed: 15758009.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3    Weller, M.4    Fisher, B.5
  • 4
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • 10.1158/0008-5472.CAN-04-1364
    • Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, et al. (2004) Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64: 7011-7021. doi:10.1158/0008-5472.CAN-04-1364. PubMed: 15466194.
    • (2004) Cancer Res , vol.64 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3    Cipelletti, B.4    Gritti, A.5
  • 5
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • 10.1038/nature03128
    • Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, et al. (2004) Identification of human brain tumour initiating cells. Nature 432: 396-401. doi:10.1038/nature03128. PubMed: 15549107.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3    Squire, J.A.4    Bayani, J.5
  • 6
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • 10.1038/nature05236
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, et al. (2006) Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760. doi:10.1038/nature05236. PubMed: 17051156.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5
  • 7
    • 33845610993 scopus 로고    scopus 로고
    • Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
    • 10.1038/nature05349
    • Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, et al. (2006) Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature 444: 761-765. doi:10.1038/nature05349. PubMed: 17151667.
    • (2006) Nature , vol.444 , pp. 761-765
    • Piccirillo, S.G.1    Reynolds, B.A.2    Zanetti, N.3    Lamorte, G.4    Binda, E.5
  • 8
    • 77952329017 scopus 로고    scopus 로고
    • Differentiation therapy exerts antitumor effects on stem-like glioma cells
    • 10.1158/1078-0432.CCR-09-1800
    • Campos B, Wan F, Farhadi M, Ernst A, Zeppernick F, et al. (2010) Differentiation therapy exerts antitumor effects on stem-like glioma cells. Clin Cancer Res Off J Am Assoc Cancer Res 16: 2715-2728. doi:10.1158/1078-0432.CCR-09-1800. PubMed: 20442299.
    • (2010) Clin Cancer Res Off J Am Assoc Cancer Res , vol.16 , pp. 2715-2728
    • Campos, B.1    Wan, F.2    Farhadi, M.3    Ernst, A.4    Zeppernick, F.5
  • 9
    • 80051800349 scopus 로고    scopus 로고
    • Blockade of the NFkappaB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo
    • 10.1038/onc.2011.74
    • Nogueira L, Ruiz-Ontañon P, Vazquez-Barquero A, Lafarga M, Berciano MT, et al. (2011) Blockade of the NFkappaB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo. Oncogene 30: 3537-3548. doi:10.1038/onc.2011.74. PubMed: 21423202.
    • (2011) Oncogene , vol.30 , pp. 3537-3548
    • Nogueira, L.1    Ruiz-Ontañon, P.2    Vazquez-Barquero, A.3    Lafarga, M.4    Berciano, M.T.5
  • 10
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • 10.1016/j.cell.2009.01.002
    • Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233. doi:10.1016/j.cell.2009.01.002. PubMed: 19167326.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 11
    • 76649086338 scopus 로고    scopus 로고
    • RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells
    • 10.1242/jcs.059659
    • Kawase-Koga Y, Low R, Otaegi G, Pollock A, Deng H, et al. (2010) RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells. J Cell Sci 123: 586-594. doi:10.1242/jcs.059659. PubMed: 20103535.
    • (2010) J Cell Sci , vol.123 , pp. 586-594
    • Kawase-Koga, Y.1    Low, R.2    Otaegi, G.3    Pollock, A.4    Deng, H.5
  • 12
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • 10.1038/nature03702
    • Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838. doi:10.1038/nature03702. PubMed: 15944708.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3    Alvarez-Saavedra, E.4    Lamb, J.5
  • 13
    • 74249114116 scopus 로고    scopus 로고
    • MicroRNAs and glioblastoma; the stem cell connection
    • 10.1038/cdd.2009.71
    • Godlewski J, Newton HB, Chiocca EA, Lawler SE, (2010) MicroRNAs and glioblastoma; the stem cell connection. Cell Death Differ 17: 221-228. doi:10.1038/cdd.2009.71. PubMed: 19521422.
    • (2010) Cell Death Differ , vol.17 , pp. 221-228
    • Godlewski, J.1    Newton, H.B.2    Chiocca, E.A.3    Lawler, S.E.4
  • 14
    • 48949116262 scopus 로고    scopus 로고
    • miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
    • 10.1186/1741-7015-6-14
    • Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, et al. (2008) miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 6: 14. doi:10.1186/1741-7015-6-14. PubMed: 18577219.
    • (2008) BMC Med , vol.6 , pp. 14
    • Silber, J.1    Lim, D.A.2    Petritsch, C.3    Persson, A.I.4    Maunakea, A.K.5
  • 15
    • 33745393103 scopus 로고    scopus 로고
    • RNAi based approaches to the treatment of malignant glioma
    • 16700622
    • Mathupala SP, Guthikonda M, Sloan AE, (2006) RNAi based approaches to the treatment of malignant glioma. Technol Cancer Res Treat 5: 261-269. PubMed: 16700622.
    • (2006) Technol Cancer Res Treat , vol.5 , pp. 261-269
    • Mathupala, S.P.1    Guthikonda, M.2    Sloan, A.E.3
  • 16
    • 84877937046 scopus 로고    scopus 로고
    • Cellular Plasticity Confers Migratory and Invasive Advantages to a Population of Glioblastoma-initiating Cells that Infiltrate Peritumoral Tissue
    • 23401361
    • Ruiz-Ontañon P, Orgaz JL, Aldaz B, Elosegui-Artola A, Martino J, et al. (2013) Cellular Plasticity Confers Migratory and Invasive Advantages to a Population of Glioblastoma-initiating Cells that Infiltrate Peritumoral Tissue. Stem Cells, 31: 1075-85. PubMed: 23401361.
    • (2013) Stem Cells , vol.31 , pp. 1075-1085
    • Ruiz-Ontañon, P.1    Orgaz, J.L.2    Aldaz, B.3    Elosegui-Artola, A.4    Martino, J.5
  • 17
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • 14522905
    • Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, et al. (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828. PubMed: 14522905.
    • (2003) Cancer Res , vol.63 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3    Bonn, V.E.4    Hawkins, C.5
  • 18
    • 45549098904 scopus 로고    scopus 로고
    • Directed mutagenesis using the polymerase chain reaction
    • Unit 411
    • Cormack B, (2001) Directed mutagenesis using the polymerase chain reaction. Curr Protoc Neurosci Chapter 4Unit 411. PubMed: 1826527718428475.
    • (2001) Curr Protoc Neurosci Chapter , vol.4
    • Cormack, B.1
  • 19
    • 79961079532 scopus 로고    scopus 로고
    • A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma
    • 10.1073/pnas.1018941108
    • Beltran E, Fresquet V, Martinez-Useros J, Richter-Larrea JA, Sagardoy A, et al. (2011) A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma. Proc Natl Acad Sci U S A 108: 12461-12466. doi:10.1073/pnas.1018941108. PubMed: 21746927.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 12461-12466
    • Beltran, E.1    Fresquet, V.2    Martinez-Useros, J.3    Richter-Larrea, J.A.4    Sagardoy, A.5
  • 20
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • 16646809
    • Smyth GK, (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol, 3: 3. PubMed: 16646809.
    • (2004) Stat Appl Genet Mol Biol , vol.3 , pp. 3
    • Smyth, G.K.1
  • 21
    • 0032441150 scopus 로고    scopus 로고
    • Cluster analysis and display of genome-wide expression patterns
    • 10.1073/pnas.95.25.14863
    • Eisen MB, Spellman PT, Brown PO, Botstein D, (1998) Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 95: 14863-14868. doi:10.1073/pnas.95.25.14863. PubMed: 9843981.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14863-14868
    • Eisen, M.B.1    Spellman, P.T.2    Brown, P.O.3    Botstein, D.4
  • 23
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • 18955434
    • Friedman RC, Farh KK, Burge CB, Bartel DP, (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92-105. PubMed: 18955434.
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 24
    • 33644756532 scopus 로고    scopus 로고
    • A genome-wide map of conserved microRNA targets in C. elegans
    • 10.1016/j.cub.2006.01.050
    • Lall S, Grün D, Krek A, Chen K, Wang YL, et al. (2006) A genome-wide map of conserved microRNA targets in C. elegans. Curr Biol 16: 460-471. doi:10.1016/j.cub.2006.01.050. PubMed: 16458514.
    • (2006) Curr Biol , vol.16 , pp. 460-471
    • Lall, S.1    Grün, D.2    Krek, A.3    Chen, K.4    Wang, Y.L.5
  • 25
    • 34748821761 scopus 로고    scopus 로고
    • The role of site accessibility in microRNA target recognition
    • 10.1038/ng2135
    • Kertesz M, Iovino N, Unnerstall U, Gaul U, Segal E, (2007) The role of site accessibility in microRNA target recognition. Nat Genet 39: 1278-1284. doi:10.1038/ng2135. PubMed: 17893677.
    • (2007) Nat Genet , vol.39 , pp. 1278-1284
    • Kertesz, M.1    Iovino, N.2    Unnerstall, U.3    Gaul, U.4    Segal, E.5
  • 26
    • 38549124383 scopus 로고    scopus 로고
    • The microRNA.org resource: targets and expression
    • 10.1093/nar/gkn715
    • Betel D, Wilson M, Gabow A, Marks DS, Sander C, (2008) The microRNA.org resource: targets and expression. Nucleic Acids Res 36: D149-D153. doi:10.1093/nar/gkn715. PubMed: 18158296.
    • (2008) Nucleic Acids Res , vol.36
    • Betel, D.1    Wilson, M.2    Gabow, A.3    Marks, D.S.4    Sander, C.5
  • 29
    • 84863132744 scopus 로고    scopus 로고
    • Sprouty1 regulates neural and endothelial differentiation of mouse embryonic stem cells
    • 10.1089/scd.2011.0110
    • Jung JE, Moon SH, Kim DK, Choi C, Song J, et al. (2012) Sprouty1 regulates neural and endothelial differentiation of mouse embryonic stem cells. Stem Cells Dev 21: 554-561. doi:10.1089/scd.2011.0110. PubMed: 21595564.
    • (2012) Stem Cells Dev , vol.21 , pp. 554-561
    • Jung, J.E.1    Moon, S.H.2    Kim, D.K.3    Choi, C.4    Song, J.5
  • 30
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • 10.1038/nature07511
    • Thum T, Gross C, Fiedler J, Fischer T, Kissler S, et al. (2008) MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456: 980-984. doi:10.1038/nature07511. PubMed: 19043405.
    • (2008) Nature , vol.456 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3    Fischer, T.4    Kissler, S.5
  • 31
    • 79959918202 scopus 로고    scopus 로고
    • Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis
    • 10.1073/pnas.1103735108
    • Ma X, Kumar M, Choudhury SN, Becker Buscaglia LE, Barker JR, et al. (2011) Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis. Proc Natl Acad Sci U S A 108: 10144-10149. doi:10.1073/pnas.1103735108. PubMed: 21646541.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10144-10149
    • Ma, X.1    Kumar, M.2    Choudhury, S.N.3    Becker Buscaglia, L.E.4    Barker, J.R.5
  • 32
    • 34548687035 scopus 로고    scopus 로고
    • mir-29 regulates Mcl-1 protein expression and apoptosis
    • 10.1038/sj.onc.1210436
    • Mott JL, Kobayashi S, Bronk SF, Gores GJ, (2007) mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 26: 6133-6140. doi:10.1038/sj.onc.1210436. PubMed: 17404574.
    • (2007) Oncogene , vol.26 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 33
    • 84868371012 scopus 로고    scopus 로고
    • Growth factors from tumor microenvironment possibly promote the proliferation of glioblastoma-derived stem-like cells in vitro
    • 10.1007/s12253-012-9543-7
    • Guo J, Niu R, Huang W, Zhou M, Shi J, et al. (2012) Growth factors from tumor microenvironment possibly promote the proliferation of glioblastoma-derived stem-like cells in vitro. Pathol Oncol Res 18: 1047-1057. doi:10.1007/s12253-012-9543-7. PubMed: 22996727.
    • (2012) Pathol Oncol Res , vol.18 , pp. 1047-1057
    • Guo, J.1    Niu, R.2    Huang, W.3    Zhou, M.4    Shi, J.5
  • 34
    • 79955514336 scopus 로고    scopus 로고
    • A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs
    • 10.1158/0008-5472.CAN-10-4117
    • Kim TM, Huang W, Park R, Park PJ, Johnson MD, (2011) A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs. Cancer Res 71: 3387-3399. doi:10.1158/0008-5472.CAN-10-4117. PubMed: 21385897.
    • (2011) Cancer Res , vol.71 , pp. 3387-3399
    • Kim, T.M.1    Huang, W.2    Park, R.3    Park, P.J.4    Johnson, M.D.5
  • 35
    • 74449085338 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein-expressing neural progenitors give rise to immature neurons via early intermediate progenitors expressing both glial fibrillary acidic protein and neuronal markers in the adult hippocampus
    • 10.1016/j.neuroscience.2009.12.026
    • Liu Y, Namba T, Liu J, Suzuki R, Shioda S, et al. (2010) Glial fibrillary acidic protein-expressing neural progenitors give rise to immature neurons via early intermediate progenitors expressing both glial fibrillary acidic protein and neuronal markers in the adult hippocampus. Neuroscience 166: 241-251. doi:10.1016/j.neuroscience.2009.12.026. PubMed: 20026190.
    • (2010) Neuroscience , vol.166 , pp. 241-251
    • Liu, Y.1    Namba, T.2    Liu, J.3    Suzuki, R.4    Shioda, S.5
  • 36
    • 79958098183 scopus 로고    scopus 로고
    • PDGF-B Can sustain self-renewal and tumorigenicity of experimental glioma-derived cancer-initiating cells by preventing oligodendrocyte differentiation
    • 21677873
    • Jiang Y, Boije M, Westermark B, Uhrbom L, (2011) PDGF-B Can sustain self-renewal and tumorigenicity of experimental glioma-derived cancer-initiating cells by preventing oligodendrocyte differentiation. Neoplasia 13: 492-503. PubMed: 21677873.
    • (2011) Neoplasia , vol.13 , pp. 492-503
    • Jiang, Y.1    Boije, M.2    Westermark, B.3    Uhrbom, L.4
  • 37
    • 38049062478 scopus 로고    scopus 로고
    • Posttranscriptional control of neuronal development by microRNA networks
    • 10.1016/j.tins.2007.10.004
    • Gao FB, (2008) Posttranscriptional control of neuronal development by microRNA networks. Trends Neurosci 31: 20-26. doi:10.1016/j.tins.2007.10.004. PubMed: 18054394.
    • (2008) Trends Neurosci , vol.31 , pp. 20-26
    • Gao, F.B.1
  • 39
    • 77749340705 scopus 로고    scopus 로고
    • miR-221/222 promote malignant progression of glioma through activation of the Akt pathway
    • 20198336
    • Zhang J, Han L, Ge Y, Zhou X, Zhang A, et al. (2010) miR-221/222 promote malignant progression of glioma through activation of the Akt pathway. Int J Oncol 36: 913-920. PubMed: 20198336.
    • (2010) Int J Oncol , vol.36 , pp. 913-920
    • Zhang, J.1    Han, L.2    Ge, Y.3    Zhou, X.4    Zhang, A.5
  • 40
    • 29144440077 scopus 로고    scopus 로고
    • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
    • 10.1073/pnas.0506216102
    • Felli N, Fontana L, Pelosi E, Botta R, Bonci D, et al. (2005) MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci U S A 102: 18081-18086. doi:10.1073/pnas.0506216102. PubMed: 16330772.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 18081-18086
    • Felli, N.1    Fontana, L.2    Pelosi, E.3    Botta, R.4    Bonci, D.5
  • 42
    • 84861130442 scopus 로고    scopus 로고
    • MicroRNA expression profiling of NGF-treated PC12 cells revealed a critical role for miR-221 in neuronal differentiation
    • 10.1016/j.neuint.2012.03.010
    • Hamada N, Fujita Y, Kojima T, Kitamoto A, Akao Y, et al. (2012) MicroRNA expression profiling of NGF-treated PC12 cells revealed a critical role for miR-221 in neuronal differentiation. Neurochem Int 60: 743-750. doi:10.1016/j.neuint.2012.03.010. PubMed: 22465943.
    • (2012) Neurochem Int , vol.60 , pp. 743-750
    • Hamada, N.1    Fujita, Y.2    Kojima, T.3    Kitamoto, A.4    Akao, Y.5
  • 43
    • 77952583615 scopus 로고    scopus 로고
    • The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma
    • 20219352
    • Zhi F, Chen X, Wang S, Xia X, Shi Y, et al. (2010) The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma. Eur J Cancer (Oxf, England: 1990) 46:: 1640-1649. PubMed: 20219352.
    • (2010) Eur J Cancer (Oxf, England , vol.1990 , pp. 1640-1649
    • Zhi, F.1    Chen, X.2    Wang, S.3    Xia, X.4    Shi, Y.5
  • 44
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • 10.1158/0008-5472.CAN-08-1305
    • Papagiannakopoulos T, Shapiro A, Kosik KS, (2008) MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 68: 8164-8172. doi:10.1158/0008-5472.CAN-08-1305. PubMed: 18829576.
    • (2008) Cancer Res , vol.68 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 45
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas
    • 10.1158/0008-5472.CAN-07-1045
    • Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, et al. (2007) MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res 67: 8994-9000. doi:10.1158/0008-5472.CAN-07-1045. PubMed: 17908999.
    • (2007) Cancer Res , vol.67 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5
  • 46
    • 77952963826 scopus 로고    scopus 로고
    • Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3
    • 20514462
    • Zhou X, Zhang J, Jia Q, Ren Y, Wang Y, et al. (2010) Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3. Oncol Rep 24: 195-201. PubMed: 20514462.
    • (2010) Oncol Rep , vol.24 , pp. 195-201
    • Zhou, X.1    Zhang, J.2    Jia, Q.3    Ren, Y.4    Wang, Y.5
  • 47
    • 43449100341 scopus 로고    scopus 로고
    • REST maintains self-renewal and pluripotency of embryonic stem cells
    • 10.1038/nature06863
    • Singh SK, Kagalwala MN, Parker-Thornburg J, Adams H, Majumder S, (2008) REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 453: 223-227. doi:10.1038/nature06863. PubMed: 18362916.
    • (2008) Nature , vol.453 , pp. 223-227
    • Singh, S.K.1    Kagalwala, M.N.2    Parker-Thornburg, J.3    Adams, H.4    Majumder, S.5
  • 48
    • 77949721578 scopus 로고    scopus 로고
    • Repression of Fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times
    • 10.1523/JNEUROSCI.0307-10.2010
    • Faedo A, Borello U, Rubenstein JL, (2010) Repression of Fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times. J Neurosci Off J Soc Neurosci 30: 4015-4023. doi:10.1523/JNEUROSCI.0307-10.2010. PubMed: 20237272.
    • (2010) J Neurosci Off J Soc Neurosci , vol.30 , pp. 4015-4023
    • Faedo, A.1    Borello, U.2    Rubenstein, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.