-
1
-
-
0037219686
-
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
-
Süel, G. M., Lockless, S. W., Wall, M. A., and Ranganathan, R. (2003) Evolutionarily conserved networks of residues mediate allosteric communication in proteins. Nat. Struct. Biol. 10, 59-69
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 59-69
-
-
Süel, G.M.1
Lockless, S.W.2
Wall, M.A.3
Ranganathan, R.4
-
3
-
-
0033955055
-
Protein dynamics in enzymatic catalysis: Exploration of dihydrofolate reductase
-
Radkiewicz, J. L., and Brooks, C. L. (2000) Protein dynamics in enzymatic catalysis: exploration of dihydrofolate reductase. J. Am. Chem. Soc. 122, 225-231
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 225-231
-
-
Radkiewicz, J.L.1
Brooks, C.L.2
-
4
-
-
0037022683
-
Network of coupled promoting motions in enzyme catalysis
-
Agarwal, P. K., Billeter, S. R., Rajagopalan, P. T. R., Benkovic, S. J., and Hammes-Schiffer, S. (2002) Network of coupled promoting motions in enzyme catalysis. Proc. Natl. Acad. Sci. U.S.A. 99, 2794-2799
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 2794-2799
-
-
Agarwal, P.K.1
Billeter, S.R.2
Rajagopalan, P.T.R.3
Benkovic, S.J.4
Hammes-Schiffer, S.5
-
5
-
-
0038810233
-
Correlated motion and the effect of distal mutations in dihydrofolate reductase
-
Rod, T. H., Radkiewicz, J. L., and Brooks, C. L. (2003) Correlated motion and the effect of distal mutations in dihydrofolate reductase. Proc. Natl. Acad. Sci. U.S.A. 100, 6980-6985
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 6980-6985
-
-
Rod, T.H.1
Radkiewicz, J.L.2
Brooks, C.L.3
-
6
-
-
18744380681
-
Impact of distal mutations on the network of coupled motions correlated to hydride transfer in dihydrofolate reductase
-
Wong, K. F., Selzer, T., Benkovic, S. J., and Hammes-Schiffer, S. (2005) Impact of distal mutations on the network of coupled motions correlated to hydride transfer in dihydrofolate reductase. Proc. Natl. Acad. Sci. U.S.A. 102, 6807-6812
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 6807-6812
-
-
Wong, K.F.1
Selzer, T.2
Benkovic, S.J.3
Hammes-Schiffer, S.4
-
7
-
-
33644990365
-
Hydrogen tunneling and protein motion in enzyme reactions
-
Hammes-Schiffer, S. (2006) Hydrogen tunneling and protein motion in enzyme reactions. Acc. Chem. Res. 39, 93-100
-
(2006)
Acc. Chem. Res.
, vol.39
, pp. 93-100
-
-
Hammes-Schiffer, S.1
-
8
-
-
0023668190
-
Construction and evaluation of the kinetic scheme associated with dihydrofolate-reductase from escherichia coli
-
Fierke, C. A., Johnson, K. A., and Benkovic, S. J. (1987) Construction and evaluation of the kinetic scheme associated with dihydrofolate-reductase from Escherichia coli. Biochemistry 26, 4085-4092
-
(1987)
Biochemistry
, vol.26
, pp. 4085-4092
-
-
Fierke, C.A.1
Johnson, K.A.2
Benkovic, S.J.3
-
9
-
-
0037159205
-
Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: Mutational effects on hydride transfer rates
-
Rajagopalan, P. T. R., Lutz, S., and Benkovic, S. J. (2002) Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates. Biochemistry 41, 12618-12628
-
(2002)
Biochemistry
, vol.41
, pp. 12618-12628
-
-
Rajagopalan, P.T.R.1
Lutz, S.2
Benkovic, S.J.3
-
10
-
-
84890390426
-
Relationship between femtosecond-picosecond dynamics to enzyme catalyzed H-transfer
-
Cheatum, C. M., and Kohen, A. (2013) Relationship between femtosecond-picosecond dynamics to enzyme catalyzed H-transfer. Top. Curr. Chem. 337, 1-39
-
(2013)
Top. Curr. Chem.
, vol.337
, pp. 1-39
-
-
Cheatum, C.M.1
Kohen, A.2
-
11
-
-
1842830209
-
Tunneling and coupled motion in the escherichia coli dihydrofolate reductase catalysis
-
Sikorski, R. S., Wang, L., Markham, K. A., Rajagopalan, P. T. R., Benkovic, S. J., and Kohen, A. (2004) Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis. J. Am. Chem. Soc. 126, 4778-4779
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 4778-4779
-
-
Sikorski, R.S.1
Wang, L.2
Markham, K.A.3
Rajagopalan, P.T.R.4
Benkovic, S.J.5
Kohen, A.6
-
12
-
-
84894148788
-
Extension and limits of the network of coupled motions correlated to hydride transfer in dihydrofolate reductase
-
Singh, P., Sen, A., Francis, K., and Kohen, A. (2014) Extension and limits of the network of coupled motions correlated to hydride transfer in dihydrofolate reductase. J. Am. Chem. Soc. 136, 2575-2582
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 2575-2582
-
-
Singh, P.1
Sen, A.2
Francis, K.3
Kohen, A.4
-
13
-
-
33750441144
-
Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase
-
Wang, L., Goodey, N. M., Benkovic, S. J., and Kohen, A. (2006) Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase. Proc. Natl. Acad. Sci. U.S.A. 103, 15753-15758
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 15753-15758
-
-
Wang, L.1
Goodey, N.M.2
Benkovic, S.J.3
Kohen, A.4
-
14
-
-
84875665271
-
Hydrogen tunneling links protein dynamics to enzyme catalysis
-
Klinman, J. P., and Kohen, A. (2013) Hydrogen tunneling links protein dynamics to enzyme catalysis. Annu. Rev. Biochem. 82, 471-496
-
(2013)
Annu. Rev. Biochem.
, vol.82
, pp. 471-496
-
-
Klinman, J.P.1
Kohen, A.2
-
15
-
-
78650117855
-
Update 1 of: Tunneling and dynamics in enzymatic hydride transfer
-
Nagel, Z. D., and Klinman, J. P. (2010) Update 1 of: Tunneling and Dynamics in Enzymatic Hydride Transfer. Chem. Rev. 110, PR41-PR67
-
(2010)
Chem. Rev.
, vol.110
, pp. PR41-PR67
-
-
Nagel, Z.D.1
Klinman, J.P.2
-
16
-
-
84856247363
-
Effects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction
-
Stojkovic, V., Perissinotti, L. L., Willmer, D., Benkovic, S. J., and Kohen, A. (2012) Effects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction. J. Am. Chem. Soc. 134, 1738-1745
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 1738-1745
-
-
Stojkovic, V.1
Perissinotti, L.L.2
Willmer, D.3
Benkovic, S.J.4
Kohen, A.5
-
17
-
-
84874083777
-
Fast protein motions are coupled to enzyme h-transfer reactions
-
Pudney, C. R., Guerriero, A., Baxter, N. J., Johannissen, L. O., Waltho, J. P., Hay, S., and Scrutton, N. S. (2013) Fast protein motions are coupled to enzyme H-transfer reactions. J. Am. Chem. Soc. 135, 2512-2517
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 2512-2517
-
-
Pudney, C.R.1
Guerriero, A.2
Baxter, N.J.3
Johannissen, L.O.4
Waltho, J.P.5
Hay, S.6
Scrutton, N.S.7
-
18
-
-
84902258731
-
Protein mass-modulated effects in the catalytic mechanism of dihydrofo- late reductase: Beyond promoting vibrations
-
Wang, Z., Singh, P., Czekster, C. M., Kohen, A., and Schramm, V. L. (2014) Protein mass-modulated effects in the catalytic mechanism of dihydrofo- late reductase: beyond promoting vibrations. J. Am. Chem. Soc. 136, 8333-8341
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 8333-8341
-
-
Wang, Z.1
Singh, P.2
Czekster, C.M.3
Kohen, A.4
Schramm, V.L.5
-
19
-
-
84879301337
-
Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans
-
Liu, C. T., Hanoian, P., French, J. B., Pringle, T. H., Hammes-Schiffer, S., and Benkovic, S. J. (2013) Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans. Proc. Natl. Acad. Sci. U.S.A. 110, 10159-10164
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 10159-10164
-
-
Liu, C.T.1
Hanoian, P.2
French, J.B.3
Pringle, T.H.4
Hammes-Schiffer, S.5
Benkovic, S.J.6
-
20
-
-
80052149070
-
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
-
Adamczyk, A. J., Cao, J., Kamerlin, S. C. L., and Warshel, A. (2011) Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions. Proc. Natl. Acad. Sci. U.S.A. 108, 14115-14120
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 14115-14120
-
-
Adamczyk, A.J.1
Cao, J.2
Kamerlin, S.C.L.3
Warshel, A.4
-
21
-
-
79953823548
-
A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis
-
Bhabha, G., Lee, J., Ekiert, D. C., Gam, J., Wilson, I. A., Dyson, H. J., Benkovic, S. J., and Wright, P. E. (2011) A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science 332, 234-238
-
(2011)
Science
, vol.332
, pp. 234-238
-
-
Bhabha, G.1
Lee, J.2
Ekiert, D.C.3
Gam, J.4
Wilson, I.A.5
Dyson, H.J.6
Benkovic, S.J.7
Wright, P.E.8
-
22
-
-
84858758329
-
Evidence that a 'dynamic knockout' in escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis
-
Loveridge, E. J., Behiry, E. M., Guo, J., and Allemann, R. K. (2012) Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis. Nat. Chem. 4, 292-297
-
(2012)
Nat. Chem.
, vol.4
, pp. 292-297
-
-
Loveridge, E.J.1
Behiry, E.M.2
Guo, J.3
Allemann, R.K.4
-
23
-
-
84890417015
-
Preservation of protein dynamics in dihydrofolate reductase evolution
-
Francis, K., Stojkovic, V., and Kohen, A. (2013) Preservation of protein dynamics in dihydrofolate reductase evolution. J. Biol. Chem. 288, 35961-35968
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 35961-35968
-
-
Francis, K.1
Stojkovic, V.2
Kohen, A.3
-
24
-
-
84890500765
-
Increased dynamic effects in a catalytically compromised variant of escherichia coli dihydrofolate reductase
-
Ruiz-Pernia, J. J., Luk, L. Y. P., García-Meseguer, R., Martí, S., Loveridge, E. J., Tuñón, I., Moliner, V., and Allemann, R. K. (2013) Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase. J. Am. Chem. Soc. 135, 18689-18696
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 18689-18696
-
-
Ruiz-Pernia, J.J.1
Luk, L.Y.P.2
García-Meseguer, R.3
Martí, S.4
Loveridge, E.J.5
Tuñón, I.6
Moliner, V.7
Allemann, R.K.8
-
25
-
-
0345073681
-
Tetrameric NAD-dependent alcohol dehydrogenase
-
Karlsson, A., El-Ahmad, M., Johansson, K., Shafqat, J., Jörnvall, H., Eklund, H., and Ramaswamy, S. (2003) TetramericNAD-dependent alcohol dehydrogenase. Chem. Biol. Interact. 143, 239-245
-
(2003)
Chem. Biol. Interact.
, vol.143
, pp. 239-245
-
-
Karlsson, A.1
El-Ahmad, M.2
Johansson, K.3
Shafqat, J.4
Jörnvall, H.5
Eklund, H.6
Ramaswamy, S.7
-
26
-
-
2442555149
-
Crystal structure and amide h/d exchange of binary complexes of alcohol dehydrogenase from bacillus stearothermophilus: Insight into thermostability and cofactor binding
-
Ceccarelli, C., Liang, Z.-X., Strickler, M., Prehna, G., Goldstein, B. M., Klinman, J. P., and Bahnson, B. J. (2004) Crystal structure and amide H/D exchange of binary complexes of alcohol dehydrogenase from Bacillus stearothermophilus: insight into thermostability and cofactor binding. Biochemistry 43, 5266-5277
-
(2004)
Biochemistry
, vol.43
, pp. 5266-5277
-
-
Ceccarelli, C.1
Liang, Z.-X.2
Strickler, M.3
Prehna, G.4
Goldstein, B.M.5
Klinman, J.P.6
Bahnson, B.J.7
-
27
-
-
8744220635
-
Evidence for increased local flexibility in psychrophilic alcohol dehydrogenase relative to its thermophilic homologue
-
Liang, Z.-X., Tsigos, I., Lee, T., Bouriotis, V., Resing, K. A., Ahn, N. G., and Klinman, J. P. (2004) Evidence for increased local flexibility in psychrophilic alcohol dehydrogenase relative to its thermophilic homologue. Biochemistry 43, 14676-14683
-
(2004)
Biochemistry
, vol.43
, pp. 14676-14683
-
-
Liang, Z.-X.1
Tsigos, I.2
Lee, T.3
Bouriotis, V.4
Resing, K.A.5
Ahn, N.G.6
Klinman, J.P.7
-
28
-
-
33646472959
-
Crystallization and preliminary x-ray diffraction studies of an alcohol dehydrogenase from the antarctic psychrophile moraxella sp. TAE123
-
Papanikolau, Y., Tsigos, I., Papadovasilaki, M., Bouriotis, V., and Petratos, K. (2005) Crystallization and preliminary x-ray diffraction studies of an alcohol dehydrogenase from the Antarctic psychrophile Moraxella sp. TAE123. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61, 246-248
-
(2005)
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.
, vol.61
, pp. 246-248
-
-
Papanikolau, Y.1
Tsigos, I.2
Papadovasilaki, M.3
Bouriotis, V.4
Petratos, K.5
-
29
-
-
0003532408
-
-
Taylor and Francis, London, UK
-
Wiegel, J., and Adams, M. W. W. (eds) (1998) Thermophiles: The Keys to the Molecular Evolution and the Origin of Life?, Taylor and Francis, London, UK
-
(1998)
Thermophiles: The Keys to the Molecular Evolution and the Origin of Life?
-
-
Wiegel, J.1
Adams, M.W.W.2
-
30
-
-
0024573393
-
Hydrogen tunneling in enzyme reactions
-
Cha, Y., Murray, C. J., and Klinman, J. P. (1989) Hydrogen tunneling in enzyme reactions. Science 243, 1325-1330
-
(1989)
Science
, vol.243
, pp. 1325-1330
-
-
Cha, Y.1
Murray, C.J.2
Klinman, J.P.3
-
31
-
-
0027196492
-
Unmasking of hydrogen tunneling in the horse liver alcohol dehydrogenase reaction by site-directed mutagenesis
-
Bahnson, B. J., Park, D.-H., Kim, K., Plapp, B. V., and Klinman, J. P. (1993) Unmasking of hydrogen tunneling in the horse liver alcohol dehydrogenase reaction by site-directed mutagenesis. Biochemistry 32, 5503-5507
-
(1993)
Biochemistry
, vol.32
, pp. 5503-5507
-
-
Bahnson, B.J.1
Park, D.-H.2
Kim, K.3
Plapp, B.V.4
Klinman, J.P.5
-
32
-
-
0033519723
-
Enzyme dynamics and hydrogen tunneling in a thermophilic alcohol dehydrogenase
-
Kohen, A., Gannio, R., Bartolucci, S., and Klinman, J. P. (1999) Enzyme dynamics and hydrogen tunneling in a thermophilic alcohol dehydrogenase. Nature 399, 496-499
-
(1999)
Nature
, vol.399
, pp. 496-499
-
-
Kohen, A.1
Gannio, R.2
Bartolucci, S.3
Klinman, J.P.4
-
33
-
-
0037123216
-
Temperature-dependent isotope effects in soybean lipoxygenase-1: Correlating hydrogen tunneling with protein dynamics
-
Knapp, M. J., Rickert, K., and Klinman, J. P. (2002) Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics. J. Am. Chem. Soc. 124, 3865-3874
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 3865-3874
-
-
Knapp, M.J.1
Rickert, K.2
Klinman, J.P.3
-
34
-
-
79952746514
-
Beyond tunneling corrections: Full tunneling modes for enzymatic C-H activation reactions
-
Alemann, R. Scrutton, N. RSC Publishing Cambridge
-
Klinman, J. P. (2009) Beyond tunneling corrections: full tunneling modes for enzymatic C-H activation reactions, in RS-Quantum Tunneling in Enzyme-Catalysed Reactions (Alemann, R., and Scrutton, N., eds), RSC Publishing Cambridge
-
(2009)
RS-Quantum Tunneling in Enzyme-Catalysed Reactions
-
-
Klinman, J.P.1
-
35
-
-
62249181529
-
An integrated model for enzyme catalysis emerges from studies of hydrogen tunneling
-
Klinman, J. P. (2009) An integrated model for enzyme catalysis emerges from studies of hydrogen tunneling. Chem. Phys. Lett. 471, 179-193
-
(2009)
Chem. Phys. Lett.
, vol.471
, pp. 179-193
-
-
Klinman, J.P.1
-
36
-
-
68049085675
-
A 21st century revisionist's view at a turning point in enzymology
-
st century revisionist's view at a turning point in enzymology. Nat. Chem. Biol. 5, 543-550
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 543-550
-
-
Nagel, Z.D.1
Klinman, J.P.2
-
37
-
-
3042709505
-
Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase
-
Liang, Z.-X., Lee, T., Resing, K. A., Ahn, N. G., and Klinman, J. P. (2004) Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase. Proc. Natl. Acad. Sci. U.S.A. 101, 9556-9561
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 9556-9561
-
-
Liang, Z.-X.1
Lee, T.2
Resing, K.A.3
Ahn, N.G.4
Klinman, J.P.5
-
38
-
-
36849039429
-
A hierarchy of timescales in protein dynamics is linked to enzyme catalysis
-
Henzler-Wildman, K. A., Lei, M., Thai, V., Kerns, S. J., Karplus, M., and Kern, D. (2007) A hierarchy of timescales in protein dynamics is linked to enzyme catalysis. Nature 450, 913-916
-
(2007)
Nature
, vol.450
, pp. 913-916
-
-
Henzler-Wildman, K.A.1
Lei, M.2
Thai, V.3
Kerns, S.J.4
Karplus, M.5
Kern, D.6
-
39
-
-
77957753399
-
Choreographing and enzyme's dance
-
Villali, J., and Kern, D. (2010) Choreographing and enzyme's dance. Curr. Opin. Chem. Biol. 14, 636-643
-
(2010)
Curr. Opin. Chem. Biol.
, vol.14
, pp. 636-643
-
-
Villali, J.1
Kern, D.2
-
40
-
-
79960580073
-
Impaired protein conformational landscapes as revealed in anomalous arrhenius prefactors
-
Nagel, Z. D., Dong, M., Bahnson, B. J., and Klinman, J. P. (2011) Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors. Proc. Natl. Acad. Sci. U.S.A. 108, 10520-10525
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 10520-10525
-
-
Nagel, Z.D.1
Dong, M.2
Bahnson, B.J.3
Klinman, J.P.4
-
41
-
-
84861379052
-
Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures
-
Nagel, Z. D., Meadows, C. W., Dong, M., Bahnson, B. J., and Klinman, J. P. (2012) Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures. Biochemistry 51, 4147-4156
-
(2012)
Biochemistry
, vol.51
, pp. 4147-4156
-
-
Nagel, Z.D.1
Meadows, C.W.2
Dong, M.3
Bahnson, B.J.4
Klinman, J.P.5
-
42
-
-
84898839850
-
Hydrogen tunneling in a prokaryotic lipoxygenase
-
Carr, C. A. M., and Klinman, J. P. (2014) Hydrogen tunneling in a prokaryotic lipoxygenase. Biochemistry 53, 2212-2214
-
(2014)
Biochemistry
, vol.53
, pp. 2212-2214
-
-
Carr, C.A.M.1
Klinman, J.P.2
-
43
-
-
40849097646
-
Free-energy landscape of enzyme catalysis
-
Benkovic, S. J., Hammes, G. G., and Hammes-Schiffer, S. (2008) Free-energy landscape of enzyme catalysis. Biochemistry 47, 3317-3321
-
(2008)
Biochemistry
, vol.47
, pp. 3317-3321
-
-
Benkovic, S.J.1
Hammes, G.G.2
Hammes-Schiffer, S.3
-
44
-
-
0029911695
-
Mechanisms and uses of hydrogen exchange
-
Englander, S. W., Sosnick, T. R., Englander, J. J., and Mayne, L. (1996) Mechanisms and uses of hydrogen exchange. Curr. Opin. Struct. Biol. 6, 18-23
-
(1996)
Curr. Opin. Struct. Biol.
, vol.6
, pp. 18-23
-
-
Englander, S.W.1
Sosnick, T.R.2
Englander, J.J.3
Mayne, L.4
-
45
-
-
84902491424
-
Picosecond-resolved fluorescent probes at functionally distinct tryptophans within a thermophilic alcohol dehydrogenase: Relationship of temperature-dependent changes in fluorescence to catalysis
-
Meadows, C. W., Ou, R., and Klinman, J. P. (2014) Picosecond-resolved fluorescent probes at functionally distinct tryptophans within a thermophilic alcohol dehydrogenase: relationship of temperature-dependent changes in fluorescence to catalysis. J. Phys. Chem. B 118, 6049-6061
-
(2014)
J. Phys. Chem. B
, vol.118
, pp. 6049-6061
-
-
Meadows, C.W.1
Ou, R.2
Klinman, J.P.3
-
47
-
-
3543146757
-
Impact of protein flexibility on hydride-transfer parameters in thermophilic and psychrophilic alcohol dehydrogenases
-
Liang, Z.-X., Tsigos, I., Bouriotis, V., and Klinman, J. P. (2004) Impact of protein flexibility on hydride-transfer parameters in thermophilic and psychrophilic alcohol dehydrogenases. J. Am. Chem. Soc. 126, 9500-9501
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 9500-9501
-
-
Liang, Z.-X.1
Tsigos, I.2
Bouriotis, V.3
Klinman, J.P.4
-
48
-
-
84886933840
-
Water networks contribute to enthalpy/entropy compensation in protein-ligand binding
-
Breiten, B., Lockett, M. R., Sherman, W., Fujita, S., Al-Sayah, M., Lange, H., Bowers, C. M., Heroux, A., Krilov, G., and Whitesides, G. M. (2013) Water networks contribute to enthalpy/entropy compensation in protein-ligand binding. J. Am. Chem. Soc. 135, 15579-15584
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 15579-15584
-
-
Breiten, B.1
Lockett, M.R.2
Sherman, W.3
Fujita, S.4
Al-Sayah, M.5
Lange, H.6
Bowers, C.M.7
Heroux, A.8
Krilov, G.9
Whitesides, G.M.10
-
49
-
-
0035107447
-
Entropy-enthalpy compensation: Fact or artifact?
-
Sharp, K. (2001) Entropy-enthalpy compensation: fact or artifact? Protein Sci. 10, 661-667
-
(2001)
Protein Sci.
, vol.10
, pp. 661-667
-
-
Sharp, K.1
-
50
-
-
84877899739
-
Identification of a longrange protein network that modulates active site dynamics in extremophilic alcohol dehydrogenases
-
Nagel, Z. D., Cun, S., and Klinman, J. P. (2013) Identification of a longrange protein network that modulates active site dynamics in extremophilic alcohol dehydrogenases. J. Biol. Chem. 288, 14087-14097
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 14087-14097
-
-
Nagel, Z.D.1
Cun, S.2
Klinman, J.P.3
-
51
-
-
0035914477
-
Electrostatic stabilization of a thermophilic cold shock protein
-
Perl, D., and Schmid, F. X. (2001) Electrostatic stabilization of a thermophilic cold shock protein. J. Mol. Biol. 313, 343-357
-
(2001)
J. Mol. Biol.
, vol.313
, pp. 343-357
-
-
Perl, D.1
Schmid, F.X.2
-
52
-
-
73849163221
-
Contribution of hydrophobic bonds to thermal stability of protein conformations
-
Scheraga, H. A., Nemethy, G., and Steinberg, I. Z. (1962) Contribution of hydrophobic bonds to thermal stability of protein conformations. J. Biol. Chem. 237, 2506-2508
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 2506-2508
-
-
Scheraga, H.A.1
Nemethy, G.2
Steinberg, I.Z.3
-
53
-
-
77249084607
-
The hydrophobic effect and its role in cold denaturation
-
Dias, C. L., Ala-Nissila, T., Wong-ekkabut, J., Vattulainen, I., Grant, M., and K arttun en, M. (2010) The hydrophobic effect and its role in cold denaturation. Cryobiology 60, 91-99
-
(2010)
Cryobiology
, vol.60
, pp. 91-99
-
-
Dias, C.L.1
Ala-Nissila, T.2
Wong-ekkabut, J.3
Vattulainen, I.4
Grant, M.5
Karttunen, M.6
-
55
-
-
71449103005
-
Hidden alternative structures of proline isomerase essential for catalysis
-
Fraser, J. S., Clarkson, M. W., Degnan, S. C., Erion, R., Kern, D., and Alber, T. (2009) Hidden alternative structures of proline isomerase essential for catalysis. Nature 462, 669-673
-
(2009)
Nature
, vol.462
, pp. 669-673
-
-
Fraser, J.S.1
Clarkson, M.W.2
Degnan, S.C.3
Erion, R.4
Kern, D.5
Alber, T.6
|