Correlated motion and the effect of distal mutations in dihydrofolate reductase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 12, 2003, Pages 6980-6985

  Rod, Thomas H ^a   Radkiewicz, Jennifer L ^a,b   Brooks III, Charles L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b OLD DOMINION UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE;

ARTICLE; BACTERIUM MUTANT; CATALYSIS; COMPUTER SIMULATION; CONFORMATIONAL TRANSITION; CORRELATION ANALYSIS; ENZYME KINETICS; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; MOTION; MUTATION; NONHUMAN; PRIORITY JOURNAL;

COMPUTER SIMULATION; ESCHERICHIA COLI; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOTION; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; TETRAHYDROFOLATE DEHYDROGENASE; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0038810233     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1230801100     Document Type: Article

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