An integrated model for enzyme catalysis emerges from studies of hydrogen tunneling

Chemical Physics Letters

Volumn 471, Issue 4-6, 2009, Pages 179-193

  Klinman, Judith P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CATALYSIS; CATALYSTS; HYDROGEN;

ACTIVE SITES; C - H ACTIVATIONS; DONOR AND ACCEPTORS; ENZYME CATALYSIS; ENZYME CATALYSTS; ENZYME SYSTEMS; INTEGRATED MODELS; INVERSE RELATIONSHIPS; PROTEIN FLEXIBILITIES; RATE ACCELERATIONS; SITE-SPECIFIC MUTAGENESIS; TUNNELING PROPERTIES;

ENZYMES;

EID: 62249181529     PISSN: 00092614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cplett.2009.01.038     Document Type: Article

References (85)

1. Wolfenden R., and Snider M.J. Acc. Chem. Res. 34 (2001) 938
2. Dwyer M.A., Looger L.L., and Hellinga H.W. Science 319 (2008) 569
3. Jiang L., et al. Science 309 (2005) 1868
4. Pauling L. Am. Sci. 36 (1948) 51
5. Wolfenden R. In: Gandour R.D., and Schowen R.L. (Eds). Transition States of Biochemical Processes (1978), Plenum Press, New York and London 558
6. Schramm V.L. Ann. Rev. Biochem. 67 (1998) 693
7. Fersht A. Enzyme Structure and Mechanism. second edn. (2007), W.H. Freeman & Co., New York 405
8. Page M.I., and Jencks W.P. Proc. Natl. Acad. Sci. USA 68 (1971) 1678
9. Schray K., and Klinman J.P. Biochim. Biophys. Res. Commun. 57 (1974) 641
10. .
11. Yang H., et al. Science 302 (2003) 262
12. Marcus R.A. Pure Appl. Chem. 69 (1997) 13
13. Marcus R.A., and Sutin N. Biochim. Biophys. Acta 811 (1985) 265
14. Sumi H., and Marcus R.A. J. Chem. Phys. 84 (1986) 4894
15. Giese B., Spochty M., and Wessely S. Pure Appl. Chem. 73 (2001) 449
16. Gray H.B., and Winkler J.R. Proc. Natl. Acad. Sci. USA 102 (2005) 3534
17. Mayer J.M. Ann. Rev. Phys. Chem. 55 (2004) 363
18. Welsh K.M., Creighton D.J., and Klinman J.P. Biochemistry 19 (1980) 2005
19. Hermes J.D., Morrical S.W., O'Leary M.H., and Cleland W.W. Biochemistry 23 (1984) 5479
20. Huskey W.P., and Schowen R.L. J. Am. Chem. Soc. 105 (1983) 5704
21. Huskey W.P. Phys. Org. Chem. 4 (1991) 361
22. Knapp M.J., Meyer M., and Klinman J.P. Hydrogen Transfer Reactions (2007), Wiley, VCH, Germany
23. Grant K.L., and Klinman J.P. Biochemistry 28 (1989) 6597
24. act by RT
25. Jonsson T., Edmondson D.E., and Klinman J.P. Biochemistry 33 (1994) 1487
26. Seymour S.L., and Klinman J.P. Biochemistry 41 (2002) 8747
27. Whittaker M.M., Ballou D.P., and Whittaker J.W. Biochemistry 37 (1998) 8426
28. Chowdhury S., and Banerjee R. J. Am. Chem. Soc. 122 (2000) 5417
29. Glickman M.H., and Klinman J.P. Biochemistry 35 (1996) 12882
30. Bollinger Jr. J.M., and Krebs C. J. Inorg. Biochem. 100 (2006) 586
31. Glickman M.H., Wiseman J., and Klinman J.P. J. Am. Chem. Soc. 116 (1994) 793
32. Hwang C.C., and Grissom C.B. J. Am. Chem. Soc. 116 (1994) 795
33. Jonsson T., Glickman M.H., and Klinman J.P. J. Am. Chem. Soc. 118 (1996) 10319
34. Knapp M.J., Rickert K., and Klinman J.P. J. Am. Chem. Soc. 124 (2002) 3865
35. Meyer M., and Klinman J.P. Proc. Natl. Acad. Sci. USA 105 (2008) 1146
36. Kuznetsov A.M., and Ulstrup A.M. Can. J. Chem. 77 (1999) 1085
37. Bruno W.J., and Bialek W. Biophys. J. 63 (1992) 689
38. Kohen A., Cannio R., Bartolucci S., and Klinman J.P. Nature 39 (1999) 496
39. Wille W.A.G., Smith A.J., Merkler D.J., and Klinman J.P. J. Am. Chem. Soc. 124 (2002) 8194
40. Basran J., Sutcliffe M.J., and Scrutton N.S. Biochemistry 38 (1999) 3218
41. Basran J., Sutcliffe M.J., and Scrutton N.S. J Biol. Chem. 276 (2001) 245
42. Harris R.J., Meskys R., Sutcliffe M.J., and Scrutton N.S. Biochemistry 39 (2000) 1189
43. Abad J.L., Camps F., and Fabrias G. Angew. Chem. Int. Ed. 39 (2000) 3279
44. Sikorski R.S., Wang L., Markham K.A., Rajagopalan P.T.R., Benkovic S.J., and Kohen A. J. Am. Chem. Soc. 12 (2004) 4778
45. Fan F., and Gadda G. Biochemistry 46 (2007) 6402
46. Gupta A., Mukherjee A., Matsui K., and Roth J.P. J. Am. Chem. Soc. 130 (2008) 11274
47. Hatcher E., Soudackov V., and Hammes-Schiffer S. J. Am. Chem. Soc. 129 (2007) 187
48. Nagel Z., and Klinman J.P. Chem. Rev. 106 (2006) 3095
49. J.P. Klinman, in: R. Allemann, N. Scrutton, (Eds.). Royal Society of Chemistry, Cambridge, 2009, pp. 132-160 .
50. Benkovic S.J., and Hammes-Schiffer S. Science 312 (2006) 208
51. Meyer M., and Klinman J.P. Chem. Phys. 319 (2005) 283
52. Karlsson A., El-Ahmad M., Johansson K., Shafqat J., Jornvall H., Eklund H., and Ramaswamy S. Chem.-Biol. Interact. 143 (2003) 239
53. Ceccarelli C., Liang Z.-X., Strickler M., Prehna G., Goldstein B.M., Klinman J.P., and Bahnson B.J. Biochemistry 43 (2004) 5266
54. Kohen A., and Klinman J.P. J. Am. Chem. Soc. 122 (2000) 10738
55. Liang Z.-X., Lee T., Resing K.A., Ahn N.G., and Klinman J.P. Proc. Natl. Acad. Sci. USA 101 (2004) 9556
56. Hoofnagle A., Resing K., and Ahn N.G. Ann. Rev. Biophys. Biol. Struct. 32 (2003) 110601
57. Geeves M.A., Koerber S.C., Dunn M.F., and Fink A.L. J. Biol. Chem. 258 (1983) 12184
58. Tsai S., and Klinman J.P. Biochemistry 40 (2001) 2303
59. Vitkup P., Ringer D., Petsko G.A., and Karplus M. Nature Struct. Biol. 7 (2000) 43
60. Bahnson B.J., Park D.-H., Kim K., Plapp B.V., and Klinman J.P. Biochemistry 31 (1993) 5503
61. Tsai S.C., and Klinman J.P. Bioorg. Chem. 31 (2003) 170
62. Fenimore P.N., Frauenfelder H., McMahon B.H., and Parak F.G. Proc. Natl. Acad. Sci. USA 99 (2002) 16047
63. The clones and conditions for expression were kindly provided by Dr. Steve Rosenberg, Chiron.
64. Kohen A., Jonsson T., and Klinman J.P. Biochemistry 36 (1997) 2603
65. Sharma S., and Klinman J.P. J. Am. Chem. Soc. 130 (2008) 17632
66. Tsai A.M., Udovic T.J., and Neumann D.A. Biophys. J. 81 (2001) 2339
67. Henzler-Widman K., and Kern D. Nature 450 (2007) 964
68. Lightstone F.C., and Bruice T.C. Bioorg. Chem. 26 (1998) 193
69. O. Oyeyemi, K.M. Sours, T. Lee, K.A. Resing, N.G. Ahn, J.P. Klinman, in preparation.
70. The representation in Fig. 9 contrasts with that used in the protein folding field, where the vertical direction (moving from unfolded to fully folded protein) is plotted as a function of enthalpy
71. Liang Z.-X., Tsigos I., Bouriotis V., and Klinman J.P. J. Am. Chem. Soc. 126 (2004) 9500
72. Wang L., Goodey M.M., Benkovic S.J., and Kohen A. Proc. Natl. Acad. Sci. USA 103 (2006) 15753
73. Z. Nagel, J.P. Klinman, in preparation.
74. Klinman J.P. Philos. Trans. Royal Soc. B 361 (2006) 21114
75. Frauenfelder H., McMahon B.H., and Fenimore P.W. Proc. Natl. Acad. Sci. USA 100 (2003) 8615
76. Hanson J.A., Duclerstacit K., Watkins L.P., Bhattacharyya S., Brokaw J., Chu J.-W., and Yang H. Proc. Natl. Acad. Sci. USA 104 (2007) 18055
77. Henzler-Wildman K.A., et al. Nature (2007) 838
78. Schnell J.R., Dyson H.J., and Wright P.E. Ann. Rev. Biophys. Biomol. Struct. 33 (2004) 119
79. Greener M. Scientist 19 (2005) 17
80. Rodgers J., Femec D.A., and Schowen R.L. J. Am. Chem. Soc. 104 (1982) 3263
81. Bahnson B.J., Colby T.D., Chin J.K., Goldstein B.M., and Klinman J.P. Proc. Natl. Acad. Sci. USA 94 (1997) 12797
82. Lockless A.W., and Ranganathan R. Science 286 (1999) 295
83. Minor W., Steczko J., Stec B., Otwinowski Z., Bolin J.T., Walter R., and Axelrod B. Biochemistry 35 (1996) 10687
84. Boyington J.C., Gaffney B., and Amzel L.M. Science 260 (1993) 1482
85. Bahnson B.J., Park D.-H., Kim K., Plapp B.V., and Klinman J.K. Biochemistry 31 (1993) 5503