Impact of protein flexibility on hydride-transfer parameters in thermophilic and psychrophilic alcohol dehydrogenases

Journal of the American Chemical Society

Volumn 126, Issue 31, 2004, Pages 9500-9501

  Liang, Zhao Xun ^a   Tsigos, Iason ^b   Bouriotis, Vassilis ^c   Klinman, Judith P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b General Chemical State Laboratory   (Greece)

^c INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE;

ARTICLE; CATALYSIS; COMPETITIVE INHIBITION; MOLECULAR CLONING; MOLECULAR DYNAMICS; NONLINEAR SYSTEM; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTON TRANSPORT; TEMPERATURE DEPENDENCE;

ALCOHOL DEHYDROGENASE; BACILLUS STEAROTHERMOPHILUS; BENZYL ALCOHOL; ENZYME ACTIVATION; HYDROGEN; KINETICS; MODELS, MOLECULAR; MORAXELLA; NAD; OXIDATION-REDUCTION; THERMODYNAMICS;

EID: 3543146757     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja047087z     Document Type: Article

References (16)

1. Kohen, A.; Klinman, J. P. Acc. Chem. Res. 1998, 31, 397-404.
2. Barsan, J.; Sutcliffe, M. J.; Scrutton, N. S. Biochemistry 1999, 38, 8, 3218-3222.
3. Knapp, M. J.; Rickert, K.; Klinman, J. P. J. Am. Chem. Soc. 2002, 124, 3865-3874.
4. Benkovic, S. J.; Hammes-Schiffer, S. Science 2003, 301, 1196-1202.
5. Kohen, A.; Cannio, R.; Bartolucci, S.; Klinman, J. P. Nature 1999, 399, 496-499.
6. Guagliardi, A.; Martino, M.; Iaccarino, I.; DeRosa, M.; Rossi, M.; Bartolucci, S. Int. J. Biochem. Cell Biol. 1996, 28, 239-246.
7. Kohen, A.; Klinman, J. P. J. Am. Chem. Soc. 2000, 122, 10738-10739.
8. Liang, Z. X.; Lee, T.; Resing, K. A.; Ahn, N. G.; Klinman, J. P. Proc. Natl. Acad. Sci. U.S.A. 2004. In press.
9. Karlsson, A.; El-Ahmad, M.; Johansson, K.; Shafqat, J.; Jornvall, H.; Eklund, H.; Ramaswamy, S. Chem. Biol. Interact. 2003, 143-144, 239-245.
10. Ceccarelli, C.; Liang, Z. X.; Strickler, M.; Prehna, G.; Goldstein, B. M.; Klinman, J. P.; Bahnson, B. J. Biochemistry 2004, 43, 5266-5277.
11. Liang, Z.-X.; Tsigos, I.; Lee, T.; Bouriotis, V.; Resing, K. A.; Ahn, N. G.; Klinman, J. P. Biochemistry, submitted.
12. Lonhienne, T.; Gerday, C.; Feller, G. Biochim. Biophys. Acta 2000, 1543, 1-10.
13. Cha, Y.; Murray, C. J.; Klinman, J. P. Science 1989, 244, 1325-1330.
14. Bahnson, B. J.; Colby, T. D.; Chin, J. K.; Goldstein, B. M.; Klinman, J. P. Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 12797-12802.
15. Marcus, R. A.; Sutin, N. Biochim. Biophys. Acta 1985, 811, 265-322.
16. Hatcher, E.; Soudackov, A. V.; Hammes-Schiffer, S. J. Am. Chem. Soc. 2004, 126, 5763-5775.