Evidence for increased local flexibility in psychrophilic alcohol dehydrogenase relative to its thermophilic homologue

Biochemistry

Volumn 43, Issue 46, 2004, Pages 14676-14683

  Liang, Zhao Xun ^a   Tsigos, Iason ^b   Lee, Thomas ^c   Bouriotis, Vassilis ^d,e   Resing, Katheryn A ^c   Ahn, Natalie G ^c,f   Klinman, Judith P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b General Chemical State Laboratory   (Greece)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF CRETE   (Greece)

^e INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC PARAMETERS; PSYCHROPHILIC ALCHOL DEHYDROGENASE (PSADH); PSYCHROPHILIC ALCOHOL;

CATALYSIS; CRYSTALLOGRAPHY; DEHYDROGENATION; DEUTERIUM; FLUORESCENCE; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROGEN; MASS SPECTROMETRY;

ALCOHOLS;

ALCOHOL DEHYDROGENASE; AMIDE; DEUTERIUM;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE SPECTROSCOPY; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TEMPERATURE; THERMOSTABILITY;

ALCOHOL DEHYDROGENASE; AMINO ACID SEQUENCE; BACILLUS STEAROTHERMOPHILUS; BACTERIAL PROTEINS; COLD; DEUTERIUM EXCHANGE MEASUREMENT; HEAT; KINETICS; MOLECULAR SEQUENCE DATA; MORAXELLA; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMODYNAMICS;

GEOBACILLUS STEAROTHERMOPHILUS; MORAXELLA SP.;

EID: 8744220635     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049004x     Document Type: Article

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