-
1
-
-
36448994709
-
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
-
Ajami B., Bennett J.L., Krieger C., Tetzlaff W., Rossi F.M. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat. Neurosci. 2007, 10:1538-1543.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 1538-1543
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
Tetzlaff, W.4
Rossi, F.M.5
-
2
-
-
0035833937
-
Immune reactivity in a mouse model of familial ALS correlates with disease progression
-
Alexianu M.E., Kozovska M., Appel S.H. Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 2001, 57:1282-1289.
-
(2001)
Neurology
, vol.57
, pp. 1282-1289
-
-
Alexianu, M.E.1
Kozovska, M.2
Appel, S.H.3
-
3
-
-
0035132167
-
Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis
-
Almer G., Guegan C., Teismann P., Naini A., Rosoklija G., Hays A.P., Chen C., Przedborski S. Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis. Ann. Neurol. 2001, 49:176-185.
-
(2001)
Ann. Neurol.
, vol.49
, pp. 176-185
-
-
Almer, G.1
Guegan, C.2
Teismann, P.3
Naini, A.4
Rosoklija, G.5
Hays, A.P.6
Chen, C.7
Przedborski, S.8
-
4
-
-
2642526164
-
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
-
Azzouz M., Ralph G.S., Storkebaum E., Walmsley L.E., Mitrophanous K.A., Kingsman S.M., Carmeliet P., Mazarakis N.D. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 2004, 429:413-417.
-
(2004)
Nature
, vol.429
, pp. 413-417
-
-
Azzouz, M.1
Ralph, G.S.2
Storkebaum, E.3
Walmsley, L.E.4
Mitrophanous, K.A.5
Kingsman, S.M.6
Carmeliet, P.7
Mazarakis, N.D.8
-
5
-
-
77957331909
-
Origin of new glial cells in intact and injured adult spinal cord
-
Barnabe-Heider F., Goritz C., Sabelstrom H., Takebayashi H., Pfrieger F.W., Meletis K., Frisen J. Origin of new glial cells in intact and injured adult spinal cord. Cell Stem Cell 2010, 7:470-482.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 470-482
-
-
Barnabe-Heider, F.1
Goritz, C.2
Sabelstrom, H.3
Takebayashi, H.4
Pfrieger, F.W.5
Meletis, K.6
Frisen, J.7
-
6
-
-
33750478657
-
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
-
Beers D.R., Henkel J.S., Xiao Q., Zhao W., Wang J., Yen A.A., Siklos L., McKercher S.R., Appel S.H. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:16021-16026.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 16021-16026
-
-
Beers, D.R.1
Henkel, J.S.2
Xiao, Q.3
Zhao, W.4
Wang, J.5
Yen, A.A.6
Siklos, L.7
McKercher, S.R.8
Appel, S.H.9
-
7
-
-
55749110043
-
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
-
Beers D.R., Henkel J.S., Zhao W., Wang J., Appel S.H. CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:15558-15563.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 15558-15563
-
-
Beers, D.R.1
Henkel, J.S.2
Zhao, W.3
Wang, J.4
Appel, S.H.5
-
8
-
-
79957528028
-
Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis
-
Beers D.R., Henkel J.S., Zhao W., Wang J., Huang A., Wen S., Liao B., Appel S.H. Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis. Brain 2011, 134:1293-1314.
-
(2011)
Brain
, vol.134
, pp. 1293-1314
-
-
Beers, D.R.1
Henkel, J.S.2
Zhao, W.3
Wang, J.4
Huang, A.5
Wen, S.6
Liao, B.7
Appel, S.H.8
-
9
-
-
0034636493
-
Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus
-
Bergles D.E., Roberts J.D., Somogyi P., Jahr C.E. Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus. Nature 2000, 405:187-191.
-
(2000)
Nature
, vol.405
, pp. 187-191
-
-
Bergles, D.E.1
Roberts, J.D.2
Somogyi, P.3
Jahr, C.E.4
-
10
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
Boillee S., Yamanaka K., Lobsiger C.S., Copeland N.G., Jenkins N.A., Kassiotis G., Kollias G., Cleveland D.W. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006, 312:1389-1392.
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillee, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
Kollias, G.7
Cleveland, D.W.8
-
11
-
-
0031051485
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
-
Bruijn L.I., Becher M.W., Lee M.K., Anderson K.L., Jenkins N.A., Copeland N.G., Sisodia S.S., Rothstein J.D., Borchelt D.R., Price D.L., Cleveland D.W. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 1997, 18:327-338.
-
(1997)
Neuron
, vol.18
, pp. 327-338
-
-
Bruijn, L.I.1
Becher, M.W.2
Lee, M.K.3
Anderson, K.L.4
Jenkins, N.A.5
Copeland, N.G.6
Sisodia, S.S.7
Rothstein, J.D.8
Borchelt, D.R.9
Price, D.L.10
Cleveland, D.W.11
-
12
-
-
84865987121
-
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
-
Butovsky O., Siddiqui S., Gabriely G., Lanser A.J., Dake B., Murugaiyan G., Doykan C.E., Wu P.M., Gali R.R., Iyer L.K., Lawson R., Berry J., Krichevsky A.M., Cudkowicz M.E., Weiner H.L. Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. J. Clin. Invest. 2012, 122:3063-3087.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3063-3087
-
-
Butovsky, O.1
Siddiqui, S.2
Gabriely, G.3
Lanser, A.J.4
Dake, B.5
Murugaiyan, G.6
Doykan, C.E.7
Wu, P.M.8
Gali, R.R.9
Iyer, L.K.10
Lawson, R.11
Berry, J.12
Krichevsky, A.M.13
Cudkowicz, M.E.14
Weiner, H.L.15
-
13
-
-
60749099023
-
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
-
Carlen M., Meletis K., Goritz C., Darsalia V., Evergren E., Tanigaki K., Amendola M., Barnabe-Heider F., Yeung M.S., Naldini L., Honjo T., Kokaia Z., Shupliakov O., Cassidy R.M., Lindvall O., Frisen J. Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke. Nat. Neurosci. 2009, 12:259-267.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 259-267
-
-
Carlen, M.1
Meletis, K.2
Goritz, C.3
Darsalia, V.4
Evergren, E.5
Tanigaki, K.6
Amendola, M.7
Barnabe-Heider, F.8
Yeung, M.S.9
Naldini, L.10
Honjo, T.11
Kokaia, Z.12
Shupliakov, O.13
Cassidy, R.M.14
Lindvall, O.15
Frisen, J.16
-
14
-
-
33645533489
-
Motor neuron degeneration promotes neural progenitor cell proliferation, migration, and neurogenesis in the spinal cords of amyotrophic lateral sclerosis mice
-
Chi L., Ke Y., Luo C., Li B., Gozal D., Kalyanaraman B., Liu R. Motor neuron degeneration promotes neural progenitor cell proliferation, migration, and neurogenesis in the spinal cords of amyotrophic lateral sclerosis mice. Stem Cells 2006, 24:34-43.
-
(2006)
Stem Cells
, vol.24
, pp. 34-43
-
-
Chi, L.1
Ke, Y.2
Luo, C.3
Li, B.4
Gozal, D.5
Kalyanaraman, B.6
Liu, R.7
-
15
-
-
56649100689
-
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS
-
Chiu I.M., Chen A., Zheng Y., Kosaras B., Tsiftsoglou S.A., Vartanian T.K., Brown R.H., Carroll M.C. T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:17913-17918.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 17913-17918
-
-
Chiu, I.M.1
Chen, A.2
Zheng, Y.3
Kosaras, B.4
Tsiftsoglou, S.A.5
Vartanian, T.K.6
Brown, R.H.7
Carroll, M.C.8
-
16
-
-
73949128974
-
Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice
-
Chiu I.M., Phatnani H., Kuligowski M., Tapia J.C., Carrasco M.A., Zhang M., Maniatis T., Carroll M.C. Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:20960-20965.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 20960-20965
-
-
Chiu, I.M.1
Phatnani, H.2
Kuligowski, M.3
Tapia, J.C.4
Carrasco, M.A.5
Zhang, M.6
Maniatis, T.7
Carroll, M.C.8
-
17
-
-
84880802569
-
A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
-
Chiu I.M., Morimoto E.T., Goodarzi H., Liao J.T., O'Keeffe S., Phatnani H.P., Muratet M., Carroll M.C., Levy S., Tavazoie S., Myers R.M., Maniatis T. A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Rep. 2013, 4:385-401.
-
(2013)
Cell Rep.
, vol.4
, pp. 385-401
-
-
Chiu, I.M.1
Morimoto, E.T.2
Goodarzi, H.3
Liao, J.T.4
O'Keeffe, S.5
Phatnani, H.P.6
Muratet, M.7
Carroll, M.C.8
Levy, S.9
Tavazoie, S.10
Myers, R.M.11
Maniatis, T.12
-
18
-
-
0141642203
-
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
-
Clement A.M., Nguyen M.D., Roberts E.A., Garcia M.L., Boillee S., Rule M., McMahon A.P., Doucette W., Siwek D., Ferrante R.J., Brown R.H., Julien J.P., Goldstein L.S., Cleveland D.W. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 2003, 302:113-117.
-
(2003)
Science
, vol.302
, pp. 113-117
-
-
Clement, A.M.1
Nguyen, M.D.2
Roberts, E.A.3
Garcia, M.L.4
Boillee, S.5
Rule, M.6
McMahon, A.P.7
Doucette, W.8
Siwek, D.9
Ferrante, R.J.10
Brown, R.H.11
Julien, J.P.12
Goldstein, L.S.13
Cleveland, D.W.14
-
19
-
-
84871756816
-
Molecular imaging of microglial activation in amyotrophic lateral sclerosis
-
Corcia P., Tauber C., Vercoullie J., Arlicot N., Prunier C., Praline J., Nicolas G., Venel Y., Hommet C., Baulieu J.L., Cottier J.P., Roussel C., Kassiou M., Guilloteau D., Ribeiro M.J. Molecular imaging of microglial activation in amyotrophic lateral sclerosis. PLoS One 2012, 7:e52941.
-
(2012)
PLoS One
, vol.7
, pp. e52941
-
-
Corcia, P.1
Tauber, C.2
Vercoullie, J.3
Arlicot, N.4
Prunier, C.5
Praline, J.6
Nicolas, G.7
Venel, Y.8
Hommet, C.9
Baulieu, J.L.10
Cottier, J.P.11
Roussel, C.12
Kassiou, M.13
Guilloteau, D.14
Ribeiro, M.J.15
-
20
-
-
0035001341
-
Glutamate uptake
-
Danbolt N.C. Glutamate uptake. Prog. Neurobiol. 2001, 65:1-105.
-
(2001)
Prog. Neurobiol.
, vol.65
, pp. 1-105
-
-
Danbolt, N.C.1
-
21
-
-
34247473080
-
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
-
Di Giorgio F.P., Carrasco M.A., Siao M.C., Maniatis T., Eggan K. Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat. Neurosci. 2007, 10:608-614.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 608-614
-
-
Di Giorgio, F.P.1
Carrasco, M.A.2
Siao, M.C.3
Maniatis, T.4
Eggan, K.5
-
22
-
-
84888807206
-
Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD
-
Diaper D.C., Adachi Y., Lazarou L., Greenstein M., Simoes F.A., Di Domenico A., Solomon D.A., Lowe S., Alsubaie R., Cheng D., Buckley S., Humphrey D.M., Shaw C.E., Hirth F. Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD. Hum. Mol. Genet. 2013, 22:3883-3893.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 3883-3893
-
-
Diaper, D.C.1
Adachi, Y.2
Lazarou, L.3
Greenstein, M.4
Simoes, F.A.5
Di Domenico, A.6
Solomon, D.A.7
Lowe, S.8
Alsubaie, R.9
Cheng, D.10
Buckley, S.11
Humphrey, D.M.12
Shaw, C.E.13
Hirth, F.14
-
23
-
-
54849404282
-
Skeletal muscle is a primary target of SOD1G93A-mediated toxicity
-
Dobrowolny G., Aucello M., Rizzuto E., Beccafico S., Mammucari C., Boncompagni S., Belia S., Wannenes F., Nicoletti C., Del Prete Z., Rosenthal N., Molinaro M., Protasi F., Fano G., Sandri M., Musaro A. Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab. 2008, 8:425-436.
-
(2008)
Cell Metab.
, vol.8
, pp. 425-436
-
-
Dobrowolny, G.1
Aucello, M.2
Rizzuto, E.3
Beccafico, S.4
Mammucari, C.5
Boncompagni, S.6
Belia, S.7
Wannenes, F.8
Nicoletti, C.9
Del Prete, Z.10
Rosenthal, N.11
Molinaro, M.12
Protasi, F.13
Fano, G.14
Sandri, M.15
Musaro, A.16
-
24
-
-
0027473452
-
Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis
-
Engelhardt J.I., Tajti J., Appel S.H. Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis. Arch. Neurol. 1993, 50:30-36.
-
(1993)
Arch. Neurol.
, vol.50
, pp. 30-36
-
-
Engelhardt, J.I.1
Tajti, J.2
Appel, S.H.3
-
25
-
-
84877832189
-
Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
-
Estes P.S., Daniel S.G., McCallum A.P., Boehringer A.V., Sukhina A.S., Zwick R.A., Zarnescu D.C. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis. Dis. Model. Mech. 2013, 6:721-733.
-
(2013)
Dis. Model. Mech.
, vol.6
, pp. 721-733
-
-
Estes, P.S.1
Daniel, S.G.2
McCallum, A.P.3
Boehringer, A.V.4
Sukhina, A.S.5
Zwick, R.A.6
Zarnescu, D.C.7
-
26
-
-
80052928827
-
Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis
-
Ferraiuolo L., Higginbottom A., Heath P.R., Barber S., Greenald D., Kirby J., Shaw P.J. Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain 2011, 134:2627-2641.
-
(2011)
Brain
, vol.134
, pp. 2627-2641
-
-
Ferraiuolo, L.1
Higginbottom, A.2
Heath, P.R.3
Barber, S.4
Greenald, D.5
Kirby, J.6
Shaw, P.J.7
-
27
-
-
79960987739
-
Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS
-
Finkelstein A., Kunis G., Seksenyan A., Ronen A., Berkutzki T., Azoulay D., Koronyo-Hamaoui M., Schwartz M. Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS. PLoS One 2011, 6:e22374.
-
(2011)
PLoS One
, vol.6
, pp. e22374
-
-
Finkelstein, A.1
Kunis, G.2
Seksenyan, A.3
Ronen, A.4
Berkutzki, T.5
Azoulay, D.6
Koronyo-Hamaoui, M.7
Schwartz, M.8
-
28
-
-
84890119907
-
Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS
-
Foust K.D., Salazar D.L., Likhite S., Ferraiuolo L., Ditsworth D., Ilieva H., Meyer K., Schmelzer L., Braun L., Cleveland D.W., Kaspar B.K. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS. Mol. Ther. 2013, 21:2148-2159.
-
(2013)
Mol. Ther.
, vol.21
, pp. 2148-2159
-
-
Foust, K.D.1
Salazar, D.L.2
Likhite, S.3
Ferraiuolo, L.4
Ditsworth, D.5
Ilieva, H.6
Meyer, K.7
Schmelzer, L.8
Braun, L.9
Cleveland, D.W.10
Kaspar, B.K.11
-
29
-
-
84895422067
-
Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis
-
Frakes A.E., Ferraiuolo L., Haidet-Phillips A.M., Schmelzer L., Braun L., Miranda C.J., Ladner K.J., Bevan A.K., Foust K.D., Godbout J.P., Popovich P.G., Guttridge D.C., Kaspar B.K. Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis. Neuron 2014, 81:1009-1023.
-
(2014)
Neuron
, vol.81
, pp. 1009-1023
-
-
Frakes, A.E.1
Ferraiuolo, L.2
Haidet-Phillips, A.M.3
Schmelzer, L.4
Braun, L.5
Miranda, C.J.6
Ladner, K.J.7
Bevan, A.K.8
Foust, K.D.9
Godbout, J.P.10
Popovich, P.G.11
Guttridge, D.C.12
Kaspar, B.K.13
-
30
-
-
84861429431
-
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity
-
Funfschilling U., Supplie L.M., Mahad D., Boretius S., Saab A.S., Edgar J., Brinkmann B.G., Kassmann C.M., Tzvetanova I.D., Mobius W., Diaz F., Meijer D., Suter U., Hamprecht B., Sereda M.W., Moraes C.T., Frahm J., Goebbels S., Nave K.A. Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature 2012, 485:517-521.
-
(2012)
Nature
, vol.485
, pp. 517-521
-
-
Funfschilling, U.1
Supplie, L.M.2
Mahad, D.3
Boretius, S.4
Saab, A.S.5
Edgar, J.6
Brinkmann, B.G.7
Kassmann, C.M.8
Tzvetanova, I.D.9
Mobius, W.10
Diaz, F.11
Meijer, D.12
Suter, U.13
Hamprecht, B.14
Sereda, M.W.15
Moraes, C.T.16
Frahm, J.17
Goebbels, S.18
Nave, K.A.19
-
31
-
-
0034651102
-
Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
-
Gong Y.H., Parsadanian A.S., Andreeva A., Snider W.D., Elliott J.L. Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration. J. Neurosci. 2000, 20:660-665.
-
(2000)
J. Neurosci.
, vol.20
, pp. 660-665
-
-
Gong, Y.H.1
Parsadanian, A.S.2
Andreeva, A.3
Snider, W.D.4
Elliott, J.L.5
-
32
-
-
79960099283
-
A pericyte origin of spinal cord scar tissue
-
Goritz C., Dias D.O., Tomilin N., Barbacid M., Shupliakov O., Frisen J. A pericyte origin of spinal cord scar tissue. Science 2011, 333:238-242.
-
(2011)
Science
, vol.333
, pp. 238-242
-
-
Goritz, C.1
Dias, D.O.2
Tomilin, N.3
Barbacid, M.4
Shupliakov, O.5
Frisen, J.6
-
33
-
-
55049120934
-
Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase
-
Gowing G., Philips T., Van Wijmeersch B., Audet J.N., Dewil M., Van Den Bosch L., Billiau A.D., Robberecht W., Julien J.P. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. J. Neurosci. 2008, 28:10234-10244.
-
(2008)
J. Neurosci.
, vol.28
, pp. 10234-10244
-
-
Gowing, G.1
Philips, T.2
Van Wijmeersch, B.3
Audet, J.N.4
Dewil, M.5
Van Den Bosch, L.6
Billiau, A.D.7
Robberecht, W.8
Julien, J.P.9
-
34
-
-
0032486428
-
Axonal swellings and degeneration in mice lacking the major proteolipid of myelin
-
Griffiths I., Klugmann M., Anderson T., Yool D., Thomson C., Schwab M.H., Schneider A., Zimmermann F., McCulloch M., Nadon N., Nave K.A. Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science 1998, 280:1610-1613.
-
(1998)
Science
, vol.280
, pp. 1610-1613
-
-
Griffiths, I.1
Klugmann, M.2
Anderson, T.3
Yool, D.4
Thomson, C.5
Schwab, M.H.6
Schneider, A.7
Zimmermann, F.8
McCulloch, M.9
Nadon, N.10
Nave, K.A.11
-
35
-
-
0141618315
-
Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice
-
Guo H., Lai L., Butchbach M.E., Stockinger M.P., Shan X., Bishop G.A., Lin C.L. Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice. Hum. Mol. Genet. 2003, 12:2519-2532.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2519-2532
-
-
Guo, H.1
Lai, L.2
Butchbach, M.E.3
Stockinger, M.P.4
Shan, X.5
Bishop, G.A.6
Lin, C.L.7
-
36
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
Gurney M.E., Pu H., Chiu A.Y., Dal Canto M.C., Polchow C.Y., Alexander D.D., Caliendo J., Hentati A., Kwon Y.W., Deng H.X., et al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 1994, 264:1772-1775.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
-
37
-
-
80052783545
-
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
-
Haidet-Phillips A.M., Hester M.E., Miranda C.J., Meyer K., Braun L., Frakes A., Song S., Likhite S., Murtha M.J., Foust K.D., Rao M., Eagle A., Kammesheidt A., Christensen A., Mendell J.R., Burghes A.H., Kaspar B.K. Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nat. Biotechnol. 2011, 29:824-828.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 824-828
-
-
Haidet-Phillips, A.M.1
Hester, M.E.2
Miranda, C.J.3
Meyer, K.4
Braun, L.5
Frakes, A.6
Song, S.7
Likhite, S.8
Murtha, M.J.9
Foust, K.D.10
Rao, M.11
Eagle, A.12
Kammesheidt, A.13
Christensen, A.14
Mendell, J.R.15
Burghes, A.H.16
Kaspar, B.K.17
-
38
-
-
84886264593
-
Altered astrocytic expression of TDP-43 does not influence motor neuron survival
-
Haidet-Phillips A.M., Gross S.K., Williams T., Tuteja A., Sherman A., Ko M., Jeong Y.H., Wong P.C., Maragakis N.J. Altered astrocytic expression of TDP-43 does not influence motor neuron survival. Exp. Neurol. 2013, 250:250-259.
-
(2013)
Exp. Neurol.
, vol.250
, pp. 250-259
-
-
Haidet-Phillips, A.M.1
Gross, S.K.2
Williams, T.3
Tuteja, A.4
Sherman, A.5
Ko, M.6
Jeong, Y.H.7
Wong, P.C.8
Maragakis, N.J.9
-
39
-
-
10744229158
-
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
-
Henkel J.S., Engelhardt J.I., Siklos L., Simpson E.P., Kim S.H., Pan T., Goodman J.C., Siddique T., Beers D.R., Appel S.H. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann. Neurol. 2004, 55:221-235.
-
(2004)
Ann. Neurol.
, vol.55
, pp. 221-235
-
-
Henkel, J.S.1
Engelhardt, J.I.2
Siklos, L.3
Simpson, E.P.4
Kim, S.H.5
Pan, T.6
Goodman, J.C.7
Siddique, T.8
Beers, D.R.9
Appel, S.H.10
-
40
-
-
33644821966
-
The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS
-
Henkel J.S., Beers D.R., Siklos L., Appel S.H. The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol. Cell. Neurosci. 2006, 31:427-437.
-
(2006)
Mol. Cell. Neurosci.
, vol.31
, pp. 427-437
-
-
Henkel, J.S.1
Beers, D.R.2
Siklos, L.3
Appel, S.H.4
-
41
-
-
84871988603
-
Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival
-
Henkel J.S., Beers D.R., Wen S., Rivera A.L., Toennis K.M., Appel J.E., Zhao W., Moore D.H., Powell S.Z., Appel S.H. Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival. EMBO Mol. Med. 2013, 5:64-79.
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 64-79
-
-
Henkel, J.S.1
Beers, D.R.2
Wen, S.3
Rivera, A.L.4
Toennis, K.M.5
Appel, J.E.6
Zhao, W.7
Moore, D.H.8
Powell, S.Z.9
Appel, S.H.10
-
42
-
-
0041833409
-
Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis
-
Hensley K., Fedynyshyn J., Ferrell S., Floyd R.A., Gordon B., Grammas P., Hamdheydari L., Mhatre M., Mou S., Pye Q.N., Stewart C., West M., West S., Williamson K.S. Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis. Neurobiol. Dis. 2003, 14:74-80.
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 74-80
-
-
Hensley, K.1
Fedynyshyn, J.2
Ferrell, S.3
Floyd, R.A.4
Gordon, B.5
Grammas, P.6
Hamdheydari, L.7
Mhatre, M.8
Mou, S.9
Pye, Q.N.10
Stewart, C.11
West, M.12
West, S.13
Williamson, K.S.14
-
43
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
-
Howland D.S., Liu J., She Y., Goad B., Maragakis N.J., Kim B., Erickson J., Kulik J., DeVito L., Psaltis G., DeGennaro L.J., Cleveland D.W., Rothstein J.D. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc. Natl. Acad. Sci. U. S. A. 2002, 99:1604-1609.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 1604-1609
-
-
Howland, D.S.1
Liu, J.2
She, Y.3
Goad, B.4
Maragakis, N.J.5
Kim, B.6
Erickson, J.7
Kulik, J.8
DeVito, L.9
Psaltis, G.10
DeGennaro, L.J.11
Cleveland, D.W.12
Rothstein, J.D.13
-
44
-
-
39849103473
-
Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice
-
Jaarsma D., Teuling E., Haasdijk E.D., De Zeeuw C.I., Hoogenraad C.C. Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice. J. Neurosci. 2008, 28:2075-2088.
-
(2008)
J. Neurosci.
, vol.28
, pp. 2075-2088
-
-
Jaarsma, D.1
Teuling, E.2
Haasdijk, E.D.3
De Zeeuw, C.I.4
Hoogenraad, C.C.5
-
45
-
-
0038147334
-
A prospective, randomized, placebo-controlled evaluation of corticoneuronal response to intrathecal BDNF therapy in ALS using magnetic resonance spectroscopy: feasibility and results
-
Kalra S., Genge A., Arnold D.L. A prospective, randomized, placebo-controlled evaluation of corticoneuronal response to intrathecal BDNF therapy in ALS using magnetic resonance spectroscopy: feasibility and results. Amyotroph. Lateral Scler. Other Motor Neuron Disord. 2003, 4:22-26.
-
(2003)
Amyotroph. Lateral Scler. Other Motor Neuron Disord.
, vol.4
, pp. 22-26
-
-
Kalra, S.1
Genge, A.2
Arnold, D.L.3
-
46
-
-
78449269355
-
NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration
-
Kang S.H., Fukaya M., Yang J.K., Rothstein J.D., Bergles D.E. NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration. Neuron 2010, 68:668-681.
-
(2010)
Neuron
, vol.68
, pp. 668-681
-
-
Kang, S.H.1
Fukaya, M.2
Yang, J.K.3
Rothstein, J.D.4
Bergles, D.E.5
-
47
-
-
84876900163
-
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
-
Kang S.H., Li Y., Fukaya M., Lorenzini I., Cleveland D.W., Ostrow L.W., Rothstein J.D., Bergles D.E. Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat. Neurosci. 2013, 16:571-579.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 571-579
-
-
Kang, S.H.1
Li, Y.2
Fukaya, M.3
Lorenzini, I.4
Cleveland, D.W.5
Ostrow, L.W.6
Rothstein, J.D.7
Bergles, D.E.8
-
48
-
-
0042528664
-
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
-
Kaspar B.K., Llado J., Sherkat N., Rothstein J.D., Gage F.H. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 2003, 301:839-842.
-
(2003)
Science
, vol.301
, pp. 839-842
-
-
Kaspar, B.K.1
Llado, J.2
Sherkat, N.3
Rothstein, J.D.4
Gage, F.H.5
-
49
-
-
0026605961
-
Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue
-
Kawamata T., Akiyama H., Yamada T., McGeer P.L. Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue. Am. J. Pathol. 1992, 140:691-707.
-
(1992)
Am. J. Pathol.
, vol.140
, pp. 691-707
-
-
Kawamata, T.1
Akiyama, H.2
Yamada, T.3
McGeer, P.L.4
-
50
-
-
69449095509
-
Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells
-
Keller A.F., Gravel M., Kriz J. Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells. Glia 2009, 57:1130-1142.
-
(2009)
Glia
, vol.57
, pp. 1130-1142
-
-
Keller, A.F.1
Gravel, M.2
Kriz, J.3
-
51
-
-
0034622930
-
Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells
-
Kondo T., Raff M. Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science 2000, 289:1754-1757.
-
(2000)
Science
, vol.289
, pp. 1754-1757
-
-
Kondo, T.1
Raff, M.2
-
52
-
-
0025868659
-
Reactive astrogliosis is widespread in the subcortical white matter of amyotrophic lateral sclerosis brain
-
Kushner P.D., Stephenson D.T., Wright S. Reactive astrogliosis is widespread in the subcortical white matter of amyotrophic lateral sclerosis brain. J. Neuropathol. Exp. Neurol. 1991, 50:263-277.
-
(1991)
J. Neuropathol. Exp. Neurol.
, vol.50
, pp. 263-277
-
-
Kushner, P.D.1
Stephenson, D.T.2
Wright, S.3
-
53
-
-
0037370361
-
Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
-
Lappe-Siefke C., Goebbels S., Gravel M., Nicksch E., Lee J., Braun P.E., Griffiths I.R., Nave K.A. Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat. Genet. 2003, 33:366-374.
-
(2003)
Nat. Genet.
, vol.33
, pp. 366-374
-
-
Lappe-Siefke, C.1
Goebbels, S.2
Gravel, M.3
Nicksch, E.4
Lee, J.5
Braun, P.E.6
Griffiths, I.R.7
Nave, K.A.8
-
54
-
-
84864200035
-
Oligodendroglia metabolically support axons and contribute to neurodegeneration
-
Lee Y., Morrison B.M., Li Y., Lengacher S., Farah M.H., Hoffman P.N., Liu Y., Tsingalia A., Jin L., Zhang P.W., Pellerin L., Magistretti P.J., Rothstein J.D. Oligodendroglia metabolically support axons and contribute to neurodegeneration. Nature 2012, 487:443-448.
-
(2012)
Nature
, vol.487
, pp. 443-448
-
-
Lee, Y.1
Morrison, B.M.2
Li, Y.3
Lengacher, S.4
Farah, M.H.5
Hoffman, P.N.6
Liu, Y.7
Tsingalia, A.8
Jin, L.9
Zhang, P.W.10
Pellerin, L.11
Magistretti, P.J.12
Rothstein, J.D.13
-
55
-
-
43449086380
-
Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration
-
Lepore A.C., Dejea C., Carmen J., Rauck B., Kerr D.A., Sofroniew M.V., Maragakis N.J. Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration. Exp. Neurol. 2008, 211:423-432.
-
(2008)
Exp. Neurol.
, vol.211
, pp. 423-432
-
-
Lepore, A.C.1
Dejea, C.2
Carmen, J.3
Rauck, B.4
Kerr, D.A.5
Sofroniew, M.V.6
Maragakis, N.J.7
-
56
-
-
54949126674
-
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease
-
Lepore A.C., Rauck B., Dejea C., Pardo A.C., Rao M.S., Rothstein J.D., Maragakis N.J. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nat. Neurosci. 2008, 11:1294-1301.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 1294-1301
-
-
Lepore, A.C.1
Rauck, B.2
Dejea, C.3
Pardo, A.C.4
Rao, M.S.5
Rothstein, J.D.6
Maragakis, N.J.7
-
57
-
-
0033485920
-
Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS)
-
Levine J.B., Kong J., Nadler M., Xu Z. Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS). Glia 1999, 28:215-224.
-
(1999)
Glia
, vol.28
, pp. 215-224
-
-
Levine, J.B.1
Kong, J.2
Nadler, M.3
Xu, Z.4
-
58
-
-
84863845583
-
Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
-
Liao B., Zhao W., Beers D.R., Henkel J.S., Appel S.H. Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS. Exp. Neurol. 2012, 237:147-152.
-
(2012)
Exp. Neurol.
, vol.237
, pp. 147-152
-
-
Liao, B.1
Zhao, W.2
Beers, D.R.3
Henkel, J.S.4
Appel, S.H.5
-
59
-
-
63149141363
-
Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice
-
Lobsiger C.S., Boillee S., McAlonis-Downes M., Khan A.M., Feltri M.L., Yamanaka K., Cleveland D.W. Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:4465-4470.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 4465-4470
-
-
Lobsiger, C.S.1
Boillee, S.2
McAlonis-Downes, M.3
Khan, A.M.4
Feltri, M.L.5
Yamanaka, K.6
Cleveland, D.W.7
-
60
-
-
77955649302
-
Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis
-
Meissner F., Molawi K., Zychlinsky A. Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:13046-13050.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 13046-13050
-
-
Meissner, F.1
Molawi, K.2
Zychlinsky, A.3
-
61
-
-
33845876647
-
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis
-
Miller T.M., Kim S.H., Yamanaka K., Hester M., Umapathi P., Arnson H., Rizo L., Mendell J.R., Gage F.H., Cleveland D.W., Kaspar B.K. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:19546-19551.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 19546-19551
-
-
Miller, T.M.1
Kim, S.H.2
Yamanaka, K.3
Hester, M.4
Umapathi, P.5
Arnson, H.6
Rizo, L.7
Mendell, J.R.8
Gage, F.H.9
Cleveland, D.W.10
Kaspar, B.K.11
-
62
-
-
84874833693
-
Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1
-
Morel L., Regan M., Higashimori H., Ng S.K., Esau C., Vidensky S., Rothstein J., Yang Y. Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1. J. Biol. Chem. 2013, 288:7105-7116.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 7105-7116
-
-
Morel, L.1
Regan, M.2
Higashimori, H.3
Ng, S.K.4
Esau, C.5
Vidensky, S.6
Rothstein, J.7
Yang, Y.8
-
63
-
-
34247475338
-
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
-
Nagai M., Re D.B., Nagata T., Chalazonitis A., Jessell T.M., Wichterle H., Przedborski S. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat. Neurosci. 2007, 10:615-622.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 615-622
-
-
Nagai, M.1
Re, D.B.2
Nagata, T.3
Chalazonitis, A.4
Jessell, T.M.5
Wichterle, H.6
Przedborski, S.7
-
64
-
-
0028264346
-
Reactive astrocytes are widespread in the cortical gray matter of amyotrophic lateral sclerosis
-
Nagy D., Kato T., Kushner P.D. Reactive astrocytes are widespread in the cortical gray matter of amyotrophic lateral sclerosis. J. Neurosci. Res. 1994, 38:336-347.
-
(1994)
J. Neurosci. Res.
, vol.38
, pp. 336-347
-
-
Nagy, D.1
Kato, T.2
Kushner, P.D.3
-
65
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D.M., Kwong L.K., Truax A.C., Micsenyi M.C., Chou T.T., Bruce J., Schuck T., Grossman M., Clark C.M., McCluskey L.F., Miller B.L., Masliah E., Mackenzie I.R., Feldman H., Feiden W., Kretzschmar H.A., Trojanowski J.Q., Lee V.M. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006, 314:130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
66
-
-
0034765498
-
Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration
-
Nguyen M.D., Julien J.P., Rivest S. Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration. Ann. Neurol. 2001, 50:630-639.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 630-639
-
-
Nguyen, M.D.1
Julien, J.P.2
Rivest, S.3
-
67
-
-
80055074312
-
Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo
-
Papadeas S.T., Kraig S.E., O'Banion C., Lepore A.C., Maragakis N.J. Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:17803-17808.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 17803-17808
-
-
Papadeas, S.T.1
Kraig, S.E.2
O'Banion, C.3
Lepore, A.C.4
Maragakis, N.J.5
-
68
-
-
68049110630
-
Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice
-
Park S., Kim H.T., Yun S., Kim I.S., Lee J., Lee I.S., Park K.I. Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice. Exp. Mol. Med. 2009, 41:487-500.
-
(2009)
Exp. Mol. Med.
, vol.41
, pp. 487-500
-
-
Park, S.1
Kim, H.T.2
Yun, S.3
Kim, I.S.4
Lee, J.5
Lee, I.S.6
Park, K.I.7
-
69
-
-
0028080101
-
Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization
-
Pellerin L., Magistretti P.J. Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:10625-10629.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 10625-10629
-
-
Pellerin, L.1
Magistretti, P.J.2
-
70
-
-
84874255781
-
Intricate interplay between astrocytes and motor neurons in ALS
-
Phatnani H.P., Guarnieri P., Friedman B.A., Carrasco M.A., Muratet M., O'Keeffe S., Nwakeze C., Pauli-Behn F., Newberry K.M., Meadows S.K., Tapia J.C., Myers R.M., Maniatis T. Intricate interplay between astrocytes and motor neurons in ALS. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:E756-E765.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. E756-E765
-
-
Phatnani, H.P.1
Guarnieri, P.2
Friedman, B.A.3
Carrasco, M.A.4
Muratet, M.5
O'Keeffe, S.6
Nwakeze, C.7
Pauli-Behn, F.8
Newberry, K.M.9
Meadows, S.K.10
Tapia, J.C.11
Myers, R.M.12
Maniatis, T.13
-
71
-
-
79951704433
-
Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease
-
Philips T., Robberecht W. Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease. Lancet Neurol. 2011, 10:253-263.
-
(2011)
Lancet Neurol.
, vol.10
, pp. 253-263
-
-
Philips, T.1
Robberecht, W.2
-
72
-
-
84874288591
-
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis
-
Philips T., Bento-Abreu A., Nonneman A., Haeck W., Staats K., Geelen V., Hersmus N., Kusters B., Van Den Bosch L., Van Damme P., Richardson W.D., Robberecht W. Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis. Brain 2013, 136:471-482.
-
(2013)
Brain
, vol.136
, pp. 471-482
-
-
Philips, T.1
Bento-Abreu, A.2
Nonneman, A.3
Haeck, W.4
Staats, K.5
Geelen, V.6
Hersmus, N.7
Kusters, B.8
Van Den Bosch, L.9
Van Damme, P.10
Richardson, W.D.11
Robberecht, W.12
-
73
-
-
0034733968
-
Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis
-
Poloni M., Facchetti D., Mai R., Micheli A., Agnoletti L., Francolini G., Mora G., Camana C., Mazzini L., Bachetti T. Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis. Neurosci. Lett. 2000, 287:211-214.
-
(2000)
Neurosci. Lett.
, vol.287
, pp. 211-214
-
-
Poloni, M.1
Facchetti, D.2
Mai, R.3
Micheli, A.4
Agnoletti, L.5
Francolini, G.6
Mora, G.7
Camana, C.8
Mazzini, L.9
Bachetti, T.10
-
74
-
-
0035873076
-
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
-
Pramatarova A., Laganiere J., Roussel J., Brisebois K., Rouleau G.A. Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J. Neurosci. 2001, 21:3369-3374.
-
(2001)
J. Neurosci.
, vol.21
, pp. 3369-3374
-
-
Pramatarova, A.1
Laganiere, J.2
Roussel, J.3
Brisebois, K.4
Rouleau, G.A.5
-
75
-
-
0242485280
-
Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain
-
Rafiki A., Boulland J.L., Halestrap A.P., Ottersen O.P., Bergersen L. Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain. Neuroscience 2003, 122:677-688.
-
(2003)
Neuroscience
, vol.122
, pp. 677-688
-
-
Rafiki, A.1
Boulland, J.L.2
Halestrap, A.P.3
Ottersen, O.P.4
Bergersen, L.5
-
76
-
-
79956221125
-
NG2-glia as multipotent neural stem cells: fact or fantasy?
-
Richardson W.D., Young K.M., Tripathi R.B., McKenzie I. NG2-glia as multipotent neural stem cells: fact or fantasy?. Neuron 2011, 70:661-673.
-
(2011)
Neuron
, vol.70
, pp. 661-673
-
-
Richardson, W.D.1
Young, K.M.2
Tripathi, R.B.3
McKenzie, I.4
-
77
-
-
56749156453
-
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
-
Rivers L.E., Young K.M., Rizzi M., Jamen F., Psachoulia K., Wade A., Kessaris N., Richardson W.D. PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat. Neurosci. 2008, 11:1392-1401.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 1392-1401
-
-
Rivers, L.E.1
Young, K.M.2
Rizzi, M.3
Jamen, F.4
Psachoulia, K.5
Wade, A.6
Kessaris, N.7
Richardson, W.D.8
-
78
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
Rothstein J.D., Martin L.J., Kuncl R.W. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 1992, 326:1464-1468.
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
79
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
-
Rothstein J.D., Dykes-Hoberg M., Pardo C.A., Bristol L.A., Jin L., Kuncl R.W., Kanai Y., Hediger M.A., Wang Y., Schielke J.P., Welty D.F. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 1996, 16:675-686.
-
(1996)
Neuron
, vol.16
, pp. 675-686
-
-
Rothstein, J.D.1
Dykes-Hoberg, M.2
Pardo, C.A.3
Bristol, L.A.4
Jin, L.5
Kuncl, R.W.6
Kanai, Y.7
Hediger, M.A.8
Wang, Y.9
Schielke, J.P.10
Welty, D.F.11
-
80
-
-
19944428649
-
Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
-
Rothstein J.D., Patel S., Regan M.R., Haenggeli C., Huang Y.H., Bergles D.E., Jin L., Dykes Hoberg M., Vidensky S., Chung D.S., Toan S.V., Bruijn L.I., Su Z.Z., Gupta P., Fisher P.B. Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature 2005, 433:73-77.
-
(2005)
Nature
, vol.433
, pp. 73-77
-
-
Rothstein, J.D.1
Patel, S.2
Regan, M.R.3
Haenggeli, C.4
Huang, Y.H.5
Bergles, D.E.6
Jin, L.7
Dykes Hoberg, M.8
Vidensky, S.9
Chung, D.S.10
Toan, S.V.11
Bruijn, L.I.12
Su, Z.Z.13
Gupta, P.14
Fisher, P.B.15
-
81
-
-
67349164383
-
A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice
-
Saxena S., Cabuy E., Caroni P. A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice. Nat. Neurosci. 2009, 12:627-636.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 627-636
-
-
Saxena, S.1
Cabuy, E.2
Caroni, P.3
-
82
-
-
0029812020
-
Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis
-
Schiffer D., Cordera S., Cavalla P., Migheli A. Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis. J. Neurol. Sci. 1996, 139:27-33. (Suppl.).
-
(1996)
J. Neurol. Sci.
, vol.139
, pp. 27-33
-
-
Schiffer, D.1
Cordera, S.2
Cavalla, P.3
Migheli, A.4
-
83
-
-
84875275232
-
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
-
Serio A., Bilican B., Barmada S.J., Ando D.M., Zhao C., Siller R., Burr K., Haghi G., Story D., Nishimura A.L., Carrasco M.A., Phatnani H.P., Shum C., Wilmut I., Maniatis T., Shaw C.E., Finkbeiner S., Chandran S. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:4697-4702.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 4697-4702
-
-
Serio, A.1
Bilican, B.2
Barmada, S.J.3
Ando, D.M.4
Zhao, C.5
Siller, R.6
Burr, K.7
Haghi, G.8
Story, D.9
Nishimura, A.L.10
Carrasco, M.A.11
Phatnani, H.P.12
Shum, C.13
Wilmut, I.14
Maniatis, T.15
Shaw, C.E.16
Finkbeiner, S.17
Chandran, S.18
-
84
-
-
77958022745
-
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
-
Shan X., Chiang P.M., Price D.L., Wong P.C. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:16325-16330.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 16325-16330
-
-
Shan, X.1
Chiang, P.M.2
Price, D.L.3
Wong, P.C.4
-
85
-
-
58149242839
-
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
-
Sorenson E.J., et al. Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology 2008, 71:1770-1775.
-
(2008)
Neurology
, vol.71
, pp. 1770-1775
-
-
Sorenson, E.J.1
-
86
-
-
56749154435
-
Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS
-
Suzuki M., McHugh J., Tork C., Shelley B., Hayes A., Bellantuono I., Aebischer P., Svendsen C.N. Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS. Mol. Ther. 2008, 16:2002-2010.
-
(2008)
Mol. Ther.
, vol.16
, pp. 2002-2010
-
-
Suzuki, M.1
McHugh, J.2
Tork, C.3
Shelley, B.4
Hayes, A.5
Bellantuono, I.6
Aebischer, P.7
Svendsen, C.N.8
-
87
-
-
41549147179
-
Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection
-
Tawfik V.L., Regan M.R., Haenggeli C., Lacroix-Fralish M.L., Nutile-McMenemy N., Perez N., Rothstein J.D., DeLeo J.A. Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection. Neuroscience 2008, 152:1086-1092.
-
(2008)
Neuroscience
, vol.152
, pp. 1086-1092
-
-
Tawfik, V.L.1
Regan, M.R.2
Haenggeli, C.3
Lacroix-Fralish, M.L.4
Nutile-McMenemy, N.5
Perez, N.6
Rothstein, J.D.7
DeLeo, J.A.8
-
88
-
-
84880217322
-
Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats
-
Tong J., Huang C., Bi F., Wu Q., Huang B., Liu X., Li F., Zhou H., Xia X.G. Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats. EMBO J. 2013, 32:1917-1926.
-
(2013)
EMBO J.
, vol.32
, pp. 1917-1926
-
-
Tong, J.1
Huang, C.2
Bi, F.3
Wu, Q.4
Huang, B.5
Liu, X.6
Li, F.7
Zhou, H.8
Xia, X.G.9
-
89
-
-
78649757441
-
NG2 glia generate new oligodendrocytes but few astrocytes in a murine experimental autoimmune encephalomyelitis model of demyelinating disease
-
Tripathi R.B., Rivers L.E., Young K.M., Jamen F., Richardson W.D. NG2 glia generate new oligodendrocytes but few astrocytes in a murine experimental autoimmune encephalomyelitis model of demyelinating disease. J. Neurosci. 2010, 30:16383-16390.
-
(2010)
J. Neurosci.
, vol.30
, pp. 16383-16390
-
-
Tripathi, R.B.1
Rivers, L.E.2
Young, K.M.3
Jamen, F.4
Richardson, W.D.5
-
90
-
-
1842471942
-
Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study
-
Turner M.R., Cagnin A., Turkheimer F.E., Miller C.C., Shaw C.E., Brooks D.J., Leigh P.N., Banati R.B. Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol. Dis. 2004, 15:601-609.
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 601-609
-
-
Turner, M.R.1
Cagnin, A.2
Turkheimer, F.E.3
Miller, C.C.4
Shaw, C.E.5
Brooks, D.J.6
Leigh, P.N.7
Banati, R.B.8
-
91
-
-
77950528523
-
Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice
-
Turner B.J., Ackerley S., Davies K.E., Talbot K. Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice. Hum. Mol. Genet. 2010, 19:815-824.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 815-824
-
-
Turner, B.J.1
Ackerley, S.2
Davies, K.E.3
Talbot, K.4
-
92
-
-
67649486844
-
The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis
-
Wang L., Sharma K., Grisotti G., Roos R.P. The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis. Neurobiol. Dis. 2009, 35:234-240.
-
(2009)
Neurobiol. Dis.
, vol.35
, pp. 234-240
-
-
Wang, L.1
Sharma, K.2
Grisotti, G.3
Roos, R.P.4
-
93
-
-
78650550891
-
Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice
-
Wang L., Gutmann D.H., Roos R.P. Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice. Hum. Mol. Genet. 2011, 20:286-293.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 286-293
-
-
Wang, L.1
Gutmann, D.H.2
Roos, R.P.3
-
94
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska I., Bell S., Cairns N.J., Miller T.M., Baloh R.H. TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:18809-18814.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
-
95
-
-
77649269011
-
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
-
Wils H., Kleinberger G., Janssens J., Pereson S., Joris G., Cuijt I., Smits V., Ceuterick-de Groote C., Van Broeckhoven C., Kumar-Singh S. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:3858-3863.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 3858-3863
-
-
Wils, H.1
Kleinberger, G.2
Janssens, J.3
Pereson, S.4
Joris, G.5
Cuijt, I.6
Smits, V.7
Ceuterick-de Groote, C.8
Van Broeckhoven, C.9
Kumar-Singh, S.10
-
96
-
-
84872363503
-
Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
-
Winkler E.A., Sengillo J.D., Sullivan J.S., Henkel J.S., Appel S.H., Zlokovic B.V. Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis. Acta Neuropathol. 2013, 125:111-120.
-
(2013)
Acta Neuropathol.
, vol.125
, pp. 111-120
-
-
Winkler, E.A.1
Sengillo, J.D.2
Sullivan, J.S.3
Henkel, J.S.4
Appel, S.H.5
Zlokovic, B.V.6
-
97
-
-
33747047814
-
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
-
Wu D.C., Re D.B., Nagai M., Ischiropoulos H., Przedborski S. The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:12132-12137.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 12132-12137
-
-
Wu, D.C.1
Re, D.B.2
Nagai, M.3
Ischiropoulos, H.4
Przedborski, S.5
-
98
-
-
44649152645
-
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice
-
Yamanaka K., Boillee S., Roberts E.A., Garcia M.L., McAlonis-Downes M., Mikse O.R., Cleveland D.W., Goldstein L.S. Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:7594-7599.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 7594-7599
-
-
Yamanaka, K.1
Boillee, S.2
Roberts, E.A.3
Garcia, M.L.4
McAlonis-Downes, M.5
Mikse, O.R.6
Cleveland, D.W.7
Goldstein, L.S.8
-
99
-
-
39749188753
-
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
-
Yamanaka K., Chun S.J., Boillee S., Fujimori-Tonou N., Yamashita H., Gutmann D.H., Takahashi R., Misawa H., Cleveland D.W. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat. Neurosci. 2008, 11:251-253.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 251-253
-
-
Yamanaka, K.1
Chun, S.J.2
Boillee, S.3
Fujimori-Tonou, N.4
Yamashita, H.5
Gutmann, D.H.6
Takahashi, R.7
Misawa, H.8
Cleveland, D.W.9
-
100
-
-
62549128641
-
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1
-
Yang Y., Gozen O., Watkins A., Lorenzini I., Lepore A., Gao Y., Vidensky S., Brennan J., Poulsen D., Won Park J., Li Jeon N., Robinson M.B., Rothstein J.D. Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1. Neuron 2009, 61:880-894.
-
(2009)
Neuron
, vol.61
, pp. 880-894
-
-
Yang, Y.1
Gozen, O.2
Watkins, A.3
Lorenzini, I.4
Lepore, A.5
Gao, Y.6
Vidensky, S.7
Brennan, J.8
Poulsen, D.9
Won Park, J.10
Li Jeon, N.11
Robinson, M.B.12
Rothstein, J.D.13
-
101
-
-
77956633377
-
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination
-
Zawadzka M., Rivers L.E., Fancy S.P., Zhao C., Tripathi R., Jamen F., Young K., Goncharevich A., Pohl H., Rizzi M., Rowitch D.H., Kessaris N., Suter U., Richardson W.D., Franklin R.J. CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell 2010, 6:578-590.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 578-590
-
-
Zawadzka, M.1
Rivers, L.E.2
Fancy, S.P.3
Zhao, C.4
Tripathi, R.5
Jamen, F.6
Young, K.7
Goncharevich, A.8
Pohl, H.9
Rizzi, M.10
Rowitch, D.H.11
Kessaris, N.12
Suter, U.13
Richardson, W.D.14
Franklin, R.J.15
-
102
-
-
84864928300
-
Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms
-
Zhao W., Beers D.R., Liao B., Henkel J.S., Appel S.H. Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms. Neurobiol. Dis. 2012, 48:418-428.
-
(2012)
Neurobiol. Dis.
, vol.48
, pp. 418-428
-
-
Zhao, W.1
Beers, D.R.2
Liao, B.3
Henkel, J.S.4
Appel, S.H.5
-
103
-
-
84882289585
-
Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis
-
Zhao W., Beers D.R., Appel S.H. Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis. J. Neuroimmune Pharmacol. 2013, 8:888-899.
-
(2013)
J. Neuroimmune Pharmacol.
, vol.8
, pp. 888-899
-
-
Zhao, W.1
Beers, D.R.2
Appel, S.H.3
-
104
-
-
41149097086
-
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
-
Zhong Z., Deane R., Ali Z., Parisi M., Shapovalov Y., O'Banion M.K., Stojanovic K., Sagare A., Boillee S., Cleveland D.W., Zlokovic B.V. ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat. Neurosci. 2008, 11:420-422.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 420-422
-
-
Zhong, Z.1
Deane, R.2
Ali, Z.3
Parisi, M.4
Shapovalov, Y.5
O'Banion, M.K.6
Stojanovic, K.7
Sagare, A.8
Boillee, S.9
Cleveland, D.W.10
Zlokovic, B.V.11
-
105
-
-
70449433875
-
Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells
-
Zhong Z., Ilieva H., Hallagan L., Bell R., Singh I., Paquette N., Thiyagarajan M., Deane R., Fernandez J.A., Lane S., Zlokovic A.B., Liu T., Griffin J.H., Chow N., Castellino F.J., Stojanovic K., Cleveland D.W., Zlokovic B.V. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. J. Clin. Invest. 2009, 119:3437-3449.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3437-3449
-
-
Zhong, Z.1
Ilieva, H.2
Hallagan, L.3
Bell, R.4
Singh, I.5
Paquette, N.6
Thiyagarajan, M.7
Deane, R.8
Fernandez, J.A.9
Lane, S.10
Zlokovic, A.B.11
Liu, T.12
Griffin, J.H.13
Chow, N.14
Castellino, F.J.15
Stojanovic, K.16
Cleveland, D.W.17
Zlokovic, B.V.18
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