Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance

Cell Reports

Volumn 9, Issue 1, 2014, Pages 366-377

  Contreras, Cristina ^a,b   González García, Ismael ^a,b   Martínez Sánchez, Noelia ^a,b   Seoane Collazo, Patricia ^a,b   Jacas, Jordi ^b,c   Morgan, Donald A ^d   Serra, Dolors ^b,e   Gallego, Rosalía ^f   Gonzalez, Francisco ^a,g   Casals, Núria ^b,c   Nogueiras, Rubén ^a,b   Rahmouni, Kamal ^d   Diéguez, Carlos ^a,b   López, Miguel ^a,b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c UNIVERSITAT INTERNACIONAL DE CATALUNYA   (Spain)

^d UNIVERSITY OF IOWA   (United States)

^e UNIVERSITY OF BARCELONA   (Spain)

^f UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^g HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CERAMIDE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INTERLEUKIN 6; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROOPIOMELANOCORTIN; PROTEIN KINASE B; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN 1;

ARTICLE; BODY WEIGHT; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENERGY BALANCE; ENERGY METABOLISM; FATTY LIVER; GENE OVEREXPRESSION; GLUCOSE HOMEOSTASIS; HYPOTHALAMUS; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPOTOXICITY; MALE; NONHUMAN; OBESITY; PATHOPHYSIOLOGY; PROTEIN FOLDING; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SYMPATHETIC NERVE; SYMPATHETIC TONE; THERMOGENESIS; WEIGHT GAIN; WEIGHT REDUCTION; ANIMAL; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; ZUCKER RAT;

ADIPOSE TISSUE, BROWN; ANIMALS; CERAMIDES; ENDOPLASMIC RETICULUM STRESS; HYPOTHALAMUS; INSULIN RESISTANCE; MALE; OBESITY; RATS; RATS, SPRAGUE-DAWLEY; RATS, ZUCKER; THERMOGENESIS; WEIGHT LOSS;

EID: 84907970671     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.08.057     Document Type: Article

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