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Volumn 26, Issue 1, 2011, Pages 125-132

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

EID: 78650664775     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/geq052     Document Type: Review
Times cited : (964)

References (73)
  • 1
    • 74049135504 scopus 로고    scopus 로고
    • Concerning the origin of malignant tumours by Theodor Boveri
    • Translated and annotated by Henry Harris
    • Boveri, T. (2008) Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris. J. Cell Sci., 121, 1-84.
    • (2008) J. Cell Sci. , vol.121 , pp. 1-84
    • Boveri, T.1
  • 2
    • 72949148505 scopus 로고
    • The significance of Howell-Jolly bodies and giant metamyelocytes in marrow smears
    • Dawson, D. W. and Bury, H. P. R. (1961) The significance of Howell-Jolly bodies and giant metamyelocytes in marrow smears. J. Clin. Path., 14, 374-378.
    • (1961) J. Clin. Path. , vol.14 , pp. 374-378
    • Dawson, D.W.1    Bury, H.P.R.2
  • 3
    • 84907116010 scopus 로고
    • The relative biological efficiency of single doses of fast neutrons and gamma-rays on Vicia faba roots and the effect of oxygen. Part II. Chromosome damage: The production of micronuclei
    • Evans, H. J., Neary, G. J. and Williamson, F. S. (1959) The relative biological efficiency of single doses of fast neutrons and gamma-rays on Vicia faba roots and the effect of oxygen. Part II. Chromosome damage: the production of micronuclei. Int. J. Radiat. Biol., 1, 216-229.
    • (1959) Int. J. Radiat. Biol. , vol.1 , pp. 216-229
    • Evans, H.J.1    Neary, G.J.2    Williamson, F.S.3
  • 4
    • 78650634544 scopus 로고
    • The viability and the average desoxy-pentosenucleic acid content of micronuclei-containing cells produced by colchicine treatment in the Ehrlich ascites tumor
    • Klein, G. and Klein, E. (1952) The viability and the average desoxy-pentosenucleic acid content of micronuclei-containing cells produced by colchicine treatment in the Ehrlich ascites tumor. Cancer Res., 12, 484-489.
    • (1952) Cancer Res. , vol.12 , pp. 484-489
    • Klein, G.1    Klein, E.2
  • 5
    • 0023874502 scopus 로고
    • A comment on the quantitative relationship between micronuclei and chromosomal aberrations
    • Savage, J. R. (1988) A comment on the quantitative relationship between micronuclei and chromosomal aberrations. Mutat. Res., 207, 33-36.
    • (1988) Mutat. Res. , vol.207 , pp. 33-36
    • Savage, J.R.1
  • 7
    • 33751119273 scopus 로고    scopus 로고
    • Chromosomal changes: Induction, detection methods and applicability in human biomonitoring
    • Mateuca, R., Lombaert, N., Aka, P. V., Decordier, I. and Kirsch-Volders, M. (2006) Chromosomal changes: induction, detection methods and applicability in human biomonitoring. Biochimie, 88, 1515-1531.
    • (2006) Biochimie , vol.88 , pp. 1515-1531
    • Mateuca, R.1    Lombaert, N.2    Aka, P.V.3    Decordier, I.4    Kirsch-Volders, M.5
  • 8
    • 34250187067 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus cytome assay
    • Fenech, M. (2007) Cytokinesis-block micronucleus cytome assay. Nat. Protoc., 2, 1084-1104.
    • (2007) Nat. Protoc. , vol.2 , pp. 1084-1104
    • Fenech, M.1
  • 9
    • 75649120068 scopus 로고    scopus 로고
    • The lymphocyte cytokinesis-block micronucleus cytome assay and its application in radiation biodosimetry
    • Fenech, M. (2010) The lymphocyte cytokinesis-block micronucleus cytome assay and its application in radiation biodosimetry. Health Phys., 98, 234-243.
    • (2010) Health Phys. , vol.98 , pp. 234-243
    • Fenech, M.1
  • 10
    • 70350088548 scopus 로고    scopus 로고
    • Mechanisms of double-strand break repair in somatic mammalian cells
    • Hartlerode, A. J. and Scully, R. (2009) Mechanisms of double-strand break repair in somatic mammalian cells. Biochem. J., 423, 157-168.
    • (2009) Biochem. J. , vol.423 , pp. 157-168
    • Hartlerode, A.J.1    Scully, R.2
  • 11
    • 77953952646 scopus 로고    scopus 로고
    • BRCA1 and BRCA2: Breast/ ovarian cancer susceptibility gene products and participants in DNA double strand break repair
    • O'Donovan, P. and Livingston, D. M. (2010) BRCA1 and BRCA2: breast/ ovarian cancer susceptibility gene products and participants in DNA double strand break repair. Carcinogenesis, 31, 961-967.
    • (2010) Carcinogenesis , vol.31 , pp. 961-967
    • O'Donovan, P.1    Livingston, D.M.2
  • 12
    • 0026064347 scopus 로고
    • Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation
    • Dianov, G. L., Timchenko, T. V., Sinitsina, O. I., Kuzminov, A. V., Medvedev, O. A. and Salganik, R. I. (1991) Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation. Mol. Gen. Genet., 225, 448-452.
    • (1991) Mol. Gen. Genet. , vol.225 , pp. 448-452
    • Dianov, G.L.1    Timchenko, T.V.2    Sinitsina, O.I.3    Kuzminov, A.V.4    Medvedev, O.A.5    Salganik, R.I.6
  • 13
    • 0037173452 scopus 로고    scopus 로고
    • Micronuclei, nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakage-fusion-bridge cycles in the cytokinesis-block micronucleus assay
    • Fenech, M. and Crott, J. W. (2002) Micronuclei, nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakage-fusion-bridge cycles in the cytokinesis-block micronucleus assay. Mutat. Res., 504, 131-136.
    • (2002) Mutat. Res. , vol.504 , pp. 131-136
    • Fenech, M.1    Crott, J.W.2
  • 14
    • 42149093769 scopus 로고    scopus 로고
    • Genome-health nutrigenomics and nutrigenetics: Nutritional requirements or 'nutriomes' for chromosomal stability and telomere maintenance at the individual level
    • Bull, C. and Fenech, M. (2008) Genome-health nutrigenomics and nutrigenetics: nutritional requirements or 'nutriomes' for chromosomal stability and telomere maintenance at the individual level. Proc. Nutr. Soc., 67, 146-156.
    • (2008) Proc. Nutr. Soc. , vol.67 , pp. 146-156
    • Bull, C.1    Fenech, M.2
  • 15
    • 0026593221 scopus 로고
    • Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes
    • Fenech, M. and Neville, S. (1992) Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes. Environ. Mol. Mutagen., 19, 27-36.
    • (1992) Environ. Mol. Mutagen. , vol.19 , pp. 27-36
    • Fenech, M.1    Neville, S.2
  • 17
    • 0038393167 scopus 로고    scopus 로고
    • What do human micronuclei contain?
    • Norppa, H. and Falck, G. C. (2003) What do human micronuclei contain? Mutagenesis, 18, 221-233.
    • (2003) Mutagenesis , vol.18 , pp. 221-233
    • Norppa, H.1    Falck, G.C.2
  • 18
    • 0028225730 scopus 로고
    • Sex chromosomes, micronuclei and aging in women
    • Hando, J. C., Nath, J. and Tucker, J. D. (1994) Sex chromosomes, micronuclei and aging in women. Chromosoma, 103, 186-192.
    • (1994) Chromosoma , vol.103 , pp. 186-192
    • Hando, J.C.1    Nath, J.2    Tucker, J.D.3
  • 19
    • 0029968510 scopus 로고    scopus 로고
    • Activation status of the X chromosome in human micronucleated lymphocytes
    • Tucker, J. D., Nath, J. and Hando, J. C. (1996) Activation status of the X chromosome in human micronucleated lymphocytes. Hum. Genet., 97, 471-475.
    • (1996) Hum. Genet. , vol.97 , pp. 471-475
    • Tucker, J.D.1    Nath, J.2    Hando, J.C.3
  • 21
    • 0031411471 scopus 로고    scopus 로고
    • X chromosome inactivation and micronuclei in normal and Turner individuals
    • Hando, J. C., Tucker, J. D., Davenport, M., Tepperberg, J. and Nath, J. (1997) X chromosome inactivation and micronuclei in normal and Turner individuals. Hum. Genet., 100, 624-628.
    • (1997) Hum. Genet. , vol.100 , pp. 624-628
    • Hando, J.C.1    Tucker, J.D.2    Davenport, M.3    Tepperberg, J.4    Nath, J.5
  • 22
    • 77952573875 scopus 로고    scopus 로고
    • Molecular and evolutionary characteristics of the fraction of human alpha satellite DNA associated with CENP-A at the centromeres of chromosomes 1, 5, 19, and 21
    • Pironon, N., Puechberty, J. and Roizès, G. (2010) Molecular and evolutionary characteristics of the fraction of human alpha satellite DNA associated with CENP-A at the centromeres of chromosomes 1, 5, 19, and 21. BMC Genomics, 11, 195-203.
    • (2010) BMC Genomics , vol.11 , pp. 195-203
    • Pironon, N.1    Puechberty, J.2    Roizès, G.3
  • 23
    • 33750353597 scopus 로고    scopus 로고
    • Structural and functional dynamics of human centromeric chromatin
    • Schueler, M. G. and Sullivan, B. A. (2006) Structural and functional dynamics of human centromeric chromatin. Annu. Rev. Genomics Hum. Genet., 7, 301-313.
    • (2006) Annu. Rev. Genomics Hum. Genet. , vol.7 , pp. 301-313
    • Schueler, M.G.1    Sullivan, B.A.2
  • 24
    • 0033547330 scopus 로고    scopus 로고
    • Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
    • Xu, G. L., Bestor, T. H., Bourc'his, D. et al. (1999) Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature, 402, 187-191.
    • (1999) Nature , vol.402 , pp. 187-191
    • Xu, G.L.1    Bestor, T.H.2    Bourc'His, D.3
  • 25
    • 49049100441 scopus 로고    scopus 로고
    • Epigenetics regulate centromere formation and kinetochore function
    • Gieni, R. S., Chan, G. and Hendzel, M. J. (2008) Epigenetics regulate centromere formation and kinetochore function. J. Cell. Biochem., 104, 2027-2039.
    • (2008) J. Cell. Biochem. , vol.104 , pp. 2027-2039
    • Gieni, R.S.1    Chan, G.2    Hendzel, M.J.3
  • 26
    • 0036696954 scopus 로고    scopus 로고
    • Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts
    • Suzuki, T., Fujii, M. and Ayusawa, D. (2002) Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts. Exp. Gerontol., 37, 1005-1014.
    • (2002) Exp. Gerontol. , vol.37 , pp. 1005-1014
    • Suzuki, T.1    Fujii, M.2    Ayusawa, D.3
  • 27
    • 0028242563 scopus 로고
    • Exclusion of specific chromosomes into micronuclei by 5-azacytidine treatment of lymphocyte cultures
    • Guttenbach, M. and Schmid, M. (1994) Exclusion of specific chromosomes into micronuclei by 5-azacytidine treatment of lymphocyte cultures. Exp. Cell Res., 211, 127-132.
    • (1994) Exp. Cell Res. , vol.211 , pp. 127-132
    • Guttenbach, M.1    Schmid, M.2
  • 28
    • 70350002274 scopus 로고    scopus 로고
    • G2 histone methylation is required for the proper segregation of chromosomes
    • Heit, R., Rattner, J. B., Chan, G. K. T. and Hendzel, M. J. (2009) G2 histone methylation is required for the proper segregation of chromosomes. J.Cell Sci., 122, 2957-2968.
    • (2009) J.Cell Sci. , vol.122 , pp. 2957-2968
    • Heit, R.1    Rattner, J.B.2    Chan, G.K.T.3    Hendzel, M.J.4
  • 29
    • 70450176266 scopus 로고    scopus 로고
    • Deviant kinetochore microtubule dynamics underlie chromosomal instability
    • Bakhoum, S. F., Genovese, G. and Compton, D. A. (2009) Deviant kinetochore microtubule dynamics underlie chromosomal instability. Curr. Biol., 19, 1937-1942.
    • (2009) Curr. Biol. , vol.19 , pp. 1937-1942
    • Bakhoum, S.F.1    Genovese, G.2    Compton, D.A.3
  • 30
    • 56149118061 scopus 로고    scopus 로고
    • Classification of chromosome segregation errors in cancer
    • Gisselsson, D. (2008) Classification of chromosome segregation errors in cancer. Chromosoma, 117, 511-519.
    • (2008) Chromosoma , vol.117 , pp. 511-519
    • Gisselsson, D.1
  • 31
    • 67649654451 scopus 로고    scopus 로고
    • Centrosome function in cancer: Guilty or innocent?
    • Zyss, D. and Gergely, F. (2009) Centrosome function in cancer: guilty or innocent? Trends Cell Biol., 19, 334-346.
    • (2009) Trends Cell Biol , vol.19 , pp. 334-346
    • Zyss, D.1    Gergely, F.2
  • 32
    • 77949362793 scopus 로고    scopus 로고
    • Whole chromosome loss is promoted by telomere dysfunction in primary cells
    • Pampalona, J., Soler, D., Genesca, A. and Tusell, L. (2010) Whole chromosome loss is promoted by telomere dysfunction in primary cells. Genes Chromosomes Cancer, 49, 368-378.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 368-378
    • Pampalona, J.1    Soler, D.2    Genesca, A.3    Tusell, L.4
  • 33
    • 0037175018 scopus 로고    scopus 로고
    • Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
    • Opresko, P. L., von Kobbe, C., Laine, J. P., Harrigan, J., Hickson, I. D. and Bohr, V. A. (2002) Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J. Biol. Chem., 277, 41110-41119.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41110-41119
    • Opresko, P.L.1    Von Kobbe, C.2    Laine, J.P.3    Harrigan, J.4    Hickson, I.D.5    Bohr, V.A.6
  • 34
    • 33747882534 scopus 로고    scopus 로고
    • Telomeres and chromosome instability
    • Murnane, J. P. (2006) Telomeres and chromosome instability. DNA Repair (Amst.), 5, 1082-1092.
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 1082-1092
    • Murnane, J.P.1
  • 35
    • 38349073475 scopus 로고    scopus 로고
    • DNA damage response at functional and dysfunctional telomeres
    • Longhese, M. P. (2008) DNA damage response at functional and dysfunctional telomeres. Genes Dev., 22, 125-140.
    • (2008) Genes Dev. , vol.22 , pp. 125-140
    • Longhese, M.P.1
  • 36
    • 25144516017 scopus 로고    scopus 로고
    • Recombination at mammalian telomeres: An alternative mechanism for telomere protection and elongation
    • Tarsounas, M. and West, S. C. (2005) Recombination at mammalian telomeres: an alternative mechanism for telomere protection and elongation. Cell Cycle, 4, 672-674.
    • (2005) Cell Cycle , vol.4 , pp. 672-674
    • Tarsounas, M.1    West, S.C.2
  • 39
    • 0037340936 scopus 로고    scopus 로고
    • Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay
    • Thomas, P., Umegaki, K. and Fenech, M. (2003) Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay. Mutagenesis, 18, 187-194.
    • (2003) Mutagenesis , vol.18 , pp. 187-194
    • Thomas, P.1    Umegaki, K.2    Fenech, M.3
  • 40
    • 66749139731 scopus 로고    scopus 로고
    • The effect of selenium, as selenomethionine, on genome stability and cytotoxicity in human lymphocytes measured using the cytokinesis-block micronucleus cytome assay
    • Wu, J., Lyons, G. H., Graham, R. D. and Fenech, M. F. (2009) The effect of selenium, as selenomethionine, on genome stability and cytotoxicity in human lymphocytes measured using the cytokinesis-block micronucleus cytome assay. Mutagenesis, 24, 225-232.
    • (2009) Mutagenesis , vol.24 , pp. 225-232
    • Wu, J.1    Lyons, G.H.2    Graham, R.D.3    Fenech, M.F.4
  • 41
    • 58149340579 scopus 로고    scopus 로고
    • Inhalative exposure to vanadium pentoxide causes DNA damage in workers: Results of a multiple end point study
    • Ehrlich, V. A., Nersesyan, A. K., Atefie, K. et al. (2008) Inhalative exposure to vanadium pentoxide causes DNA damage in workers: results of a multiple end point study. Environ. Health Perspect., 116, 1689-1693.
    • (2008) Environ. Health Perspect. , vol.116 , pp. 1689-1693
    • Ehrlich, V.A.1    Nersesyan, A.K.2    Atefie, K.3
  • 42
    • 52649132933 scopus 로고    scopus 로고
    • Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers
    • El-Zein, R. A., Fenech, M., Lopez, M. S., Spitz, M. R. and Etzel, C. J. (2008) Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers. Cancer Epidemiol. Bio-markers Prev., 17, 1111-1119.
    • (2008) Cancer Epidemiol. Bio-markers Prev. , vol.17 , pp. 1111-1119
    • El-Zein, R.A.1    Fenech, M.2    Lopez, M.S.3    Spitz, M.R.4    Etzel, C.J.5
  • 43
    • 0034066102 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils
    • Umegaki, K. and Fenech, M. (2000) Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis, 15, 261-269.
    • (2000) Mutagenesis , vol.15 , pp. 261-269
    • Umegaki, K.1    Fenech, M.2
  • 44
    • 67650072490 scopus 로고    scopus 로고
    • Biomarkers measured by cytokinesis-block micronucleus cytome assay for evaluating genetic damages induced by polycyclic aromatic hydrocarbons
    • Duan, H., Leng, S., Pan, Z. et al. (2009) Biomarkers measured by cytokinesis-block micronucleus cytome assay for evaluating genetic damages induced by polycyclic aromatic hydrocarbons. Mutat. Res., 677, 93-99.
    • (2009) Mutat. Res. , vol.677 , pp. 93-99
    • Duan, H.1    Leng, S.2    Pan, Z.3
  • 45
    • 34547192058 scopus 로고    scopus 로고
    • BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
    • Chan, K. L., North, P. S. and Hickson, I. D. (2007) BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J., 26, 3397-3409.
    • (2007) EMBO J. , vol.26 , pp. 3397-3409
    • Chan, K.L.1    North, P.S.2    Hickson, I.D.3
  • 46
    • 67349187702 scopus 로고    scopus 로고
    • The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities
    • Naim, V. and Rosselli, F. (2009) The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat. Cell Biol., 11, 761-768.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 761-768
    • Naim, V.1    Rosselli, F.2
  • 47
    • 22244481613 scopus 로고    scopus 로고
    • The structure and function of SMC and kleisin complexes
    • Nasmyth, K. and Haering, C. H. (2005) The structure and function of SMC and kleisin complexes. Annu. Rev. Biochem., 74, 595-648.
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 595-648
    • Nasmyth, K.1    Haering, C.H.2
  • 48
    • 0036045399 scopus 로고    scopus 로고
    • The clastogenic response of the 1q12 heterochromatic region to DNA cross-linking agents is independent of the Fanconi anemia pathway
    • Callén, E., Raḿirez, M. J., Creus, A. et al. (2002) The clastogenic response of the 1q12 heterochromatic region to DNA cross-linking agents is independent of the Fanconi anemia pathway. Carcinogenesis, 23, 1267-1271.
    • (2002) Carcinogenesis , vol.23 , pp. 1267-1271
    • Callén, E.1    Raḿirez, M.J.2    Creus, A.3
  • 49
    • 67349227137 scopus 로고    scopus 로고
    • Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
    • Chan, K. L., Palmai-Pallag, T., Ying, S. and Hickson, I. D. (2009) Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat. Cell Biol., 11, 753-760.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 753-760
    • Chan, K.L.1    Palmai-Pallag, T.2    Ying, S.3    Hickson, I.D.4
  • 50
    • 9244260189 scopus 로고    scopus 로고
    • When, where and how the bridge breaks: Anaphase bridge breakage plays a crucial role in gene amplification and HSR generation
    • Shimizu, N., Shingaki, K., Kaneko-Sasaguri, Y., Hashizume, T. and Kanda, T. (2005) When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation. Exp. Cell Res., 302, 233-243.
    • (2005) Exp. Cell Res. , vol.302 , pp. 233-243
    • Shimizu, N.1    Shingaki, K.2    Kaneko-Sasaguri, Y.3    Hashizume, T.4    Kanda, T.5
  • 51
    • 0026645532 scopus 로고
    • Co-amplified markers alternate in megabase long inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification
    • Toledo, F., Le Roscouet, D., Buttin, G. and Debatisse, M. (1992) Co-amplified markers alternate in megabase long inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification. EMBO J., 11, 2665-2673.
    • (1992) EMBO J. , vol.11 , pp. 2665-2673
    • Toledo, F.1    Le Roscouet, D.2    Buttin, G.3    Debatisse, M.4
  • 52
    • 0033563004 scopus 로고    scopus 로고
    • Micronuclei formation with chromosome breaks and gene amplification caused by Vpr, an accessory gene of human immunodeficiency virus
    • Shimura, M., Onozuka, Y., Yamaguchi, T., Hatake, K., Takaku, F. and Ishizaka, Y. (1999) Micronuclei formation with chromosome breaks and gene amplification caused by Vpr, an accessory gene of human immunodeficiency virus. Cancer Res., 59, 2259-2264. (Pubitemid 29242264)
    • (1999) Cancer Research , vol.59 , Issue.10 , pp. 2259-2264
    • Shimura, M.1    Onozuka, Y.2    Yamaguchi, T.3    Hatake, K.4    Takaku, F.5    Ishizaka, Y.6
  • 53
    • 0027152244 scopus 로고
    • Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells
    • Ma, C., Martin, S., Trask, B. and Hamlin, J. L. (1993) Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells. Genes Dev., 7, 605-620.
    • (1993) Genes Dev. , vol.7 , pp. 605-620
    • Ma, C.1    Martin, S.2    Trask, B.3    Hamlin, J.L.4
  • 54
    • 0032559796 scopus 로고    scopus 로고
    • Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase
    • Shimizu, N., Itoh, N., Utiyama, H. and Wahl, G. M. (1998) Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase. J. Cell Biol., 140, 1307-1320.
    • (1998) J. Cell Biol. , vol.140 , pp. 1307-1320
    • Shimizu, N.1    Itoh, N.2    Utiyama, H.3    Wahl, G.M.4
  • 55
    • 0034646365 scopus 로고    scopus 로고
    • Selective elimination of acentric double minutes from cancer cells through the extrusion of micronuclei
    • Shimizu, N., Shimuara, T. and Tanaka, T. (2000) Selective elimination of acentric double minutes from cancer cells through the extrusion of micronuclei. Mutat. Res., 448, 81-90.
    • (2000) Mutat. Res. , vol.448 , pp. 81-90
    • Shimizu, N.1    Shimuara, T.2    Tanaka, T.3
  • 57
    • 0034892585 scopus 로고    scopus 로고
    • Micronuclei and chromatid buds are the result of related genotoxic events
    • Serrano-Garcia, L. and Montero-Montaya, R. (2001) Micronuclei and chromatid buds are the result of related genotoxic events. Environ. Mol. Mutagen., 38, 38-45.
    • (2001) Environ. Mol. Mutagen. , vol.38 , pp. 38-45
    • Serrano-Garcia, L.1    Montero-Montaya, R.2
  • 58
    • 0034936018 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro
    • Crott, J. W., Mashiyama, S. T., Ames, B. N. and Fenech, M. (2001) Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro. Carcinogenesis, 22, 1019-1025.
    • (2001) Carcinogenesis , vol.22 , pp. 1019-1025
    • Crott, J.W.1    Mashiyama, S.T.2    Ames, B.N.3    Fenech, M.4
  • 59
    • 0034792891 scopus 로고    scopus 로고
    • Folic acid deficiency increases chromosome breakage and rearrangement, gene amplification and DNA-uracil content in human lymphocytes in vitro: Effect of MTHFR C677T polymorphism
    • Crott, J. W., Mashiyama, S. T., Ames, B. N. and Fenech, M. (2001) Folic acid deficiency increases chromosome breakage and rearrangement, gene amplification and DNA-uracil content in human lymphocytes in vitro: effect of MTHFR C677T polymorphism. Cancer Epidemiol. Biomarkers Prev., 10, 1089-1096.
    • (2001) Cancer Epidemiol. Biomarkers Prev. , vol.10 , pp. 1089-1096
    • Crott, J.W.1    Mashiyama, S.T.2    Ames, B.N.3    Fenech, M.4
  • 60
    • 0346726185 scopus 로고    scopus 로고
    • MTHFR C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes
    • Kimura, M., Umegaki, K., Higuchi, M., Thomas, P. and Fenech, M. (2004) MTHFR C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes. J. Nutr., 134, 48-56.
    • (2004) J. Nutr. , vol.134 , pp. 48-56
    • Kimura, M.1    Umegaki, K.2    Higuchi, M.3    Thomas, P.4    Fenech, M.5
  • 61
    • 54349097938 scopus 로고    scopus 로고
    • Multiple origins of spontaneously arising micronuclei in HeLa cells: Direct evidence from long-term live cell imaging
    • Rao, X., Zhang, Y., Yi, Q. et al. (2008) Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat. Res., 646, 41-49.
    • (2008) Mutat. Res. , vol.646 , pp. 41-49
    • Rao, X.1    Zhang, Y.2    Yi, Q.3
  • 62
    • 67349257415 scopus 로고    scopus 로고
    • A nuclear budding mechanism in transiently arrested cells generates drug-sensitive and drug-resistant cells
    • Mansilla, S., Bataller, M. and Portugal, J. (2009) A nuclear budding mechanism in transiently arrested cells generates drug-sensitive and drug-resistant cells. Biochem. Pharmacol., 78, 123-132.
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 123-132
    • Mansilla, S.1    Bataller, M.2    Portugal, J.3
  • 63
    • 71549118520 scopus 로고    scopus 로고
    • Telomere dysfunction and chromosome structure modulate the contribution of individual chromosomes in abnormal nuclear morphologies
    • Pampalona, J., Soler, D., Genescà, A. and Tusell, L. (2010) Telomere dysfunction and chromosome structure modulate the contribution of individual chromosomes in abnormal nuclear morphologies. Mutat. Res., 683, 16-22.
    • (2010) Mutat. Res. , vol.683 , pp. 16-22
    • Pampalona, J.1    Soler, D.2    Genescà, A.3    Tusell, L.4
  • 64
    • 77956315785 scopus 로고    scopus 로고
    • Emergence of micronuclei and their effects on the fate of cells under replication stress
    • Utani, K., Kohno, Y., Okamoto, A. and Shimizu, N. (2010) Emergence of micronuclei and their effects on the fate of cells under replication stress. PLoS One, 5, e10089.
    • (2010) PLoS One , vol.5
    • Utani, K.1    Kohno, Y.2    Okamoto, A.3    Shimizu, N.4
  • 65
    • 33847749516 scopus 로고    scopus 로고
    • Origin of nuclear buds and micronuclei in normal and folate-deprived human lymphocytes
    • Lindberg, H. K., Wang, X., Järventaus, H., Falck, G. C., Norppa, H. and Fenech, M. (2007) Origin of nuclear buds and micronuclei in normal and folate-deprived human lymphocytes. Mutat. Res., 617, 33-45.
    • (2007) Mutat. Res. , vol.617 , pp. 33-45
    • Lindberg, H.K.1    Wang, X.2    Järventaus, H.3    Falck, G.C.4    Norppa, H.5    Fenech, M.6
  • 67
    • 3042591660 scopus 로고    scopus 로고
    • Folate deficiency induces aneuploidy in human lymphocytes in vitro-evidence using cytokinesis-blocked cells and probes specific for chromosomes 17 and 21
    • Wang, X., Thomas, P., Xue, J. and Fenech, M. (2004) Folate deficiency induces aneuploidy in human lymphocytes in vitro-evidence using cytokinesis-blocked cells and probes specific for chromosomes 17 and 21. Mutat. Res., 551, 167-180.
    • (2004) Mutat. Res. , vol.551 , pp. 167-180
    • Wang, X.1    Thomas, P.2    Xue, J.3    Fenech, M.4
  • 69
    • 40049102810 scopus 로고    scopus 로고
    • Abnormal nuclear structures (micronuclei, nucleo-plasmic bridges, and nuclear buds) in a pleomorphic giant cell carcinoma of the stomach
    • Caruso, R. A., Fedele, F., Consolo, P., Luigiano, C., Venuti, A. and Cavallari, V. (2008) Abnormal nuclear structures (micronuclei, nucleo-plasmic bridges, and nuclear buds) in a pleomorphic giant cell carcinoma of the stomach. Ultrastruct. Pathol., 32, 11-15.
    • (2008) Ultrastruct. Pathol. , vol.32 , pp. 11-15
    • Caruso, R.A.1    Fedele, F.2    Consolo, P.3    Luigiano, C.4    Venuti, A.5    Cavallari, V.6
  • 73
    • 43149090300 scopus 로고    scopus 로고
    • Genetic polymorphisms and micronucleus formation: A review of the literature
    • Iarmarcovai, G., Bonassi, S., Botta, A., Baan, R. A. and Orsière, T. (2008) Genetic polymorphisms and micronucleus formation: a review of the literature. Mutat. Res., 658, 215-233.
    • (2008) Mutat. Res. , vol.658 , pp. 215-233
    • Iarmarcovai, G.1    Bonassi, S.2    Botta, A.3    Baan, R.A.4    Orsière, T.5


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