Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei

Cell

Volumn 154, Issue 1, 2013, Pages 47-

  Hatch, Emily M ^a   Fischer, Andrew H ^b   Deerinck, Thomas J ^c   Hetzer, Martin W ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CALRETICULIN; LAMIN B;

ANEUPLOIDY; ARTICLE; CANCER CELL CULTURE; CELL COMPARTMENTALIZATION; CELL JUNCTION; CELL NUCLEUS MEMBRANE; CHROMATIN; DNA DAMAGE; ENDOPLASMIC RETICULUM; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERPHASE; LUNG NON SMALL CELL CANCER; MICRONUCLEUS; MITOSIS; NUCLEAR EXPORT SIGNAL; NUCLEAR LAMINA; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATIC CELL;

EID: 84879956366     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.06.007     Document Type: Article

References (50)

1. M.D. Abràmoff, I. Hospitals, P.J. Magalhães, and M. Abràmoff Image processing with ImageJ Biophotonics International 11 2004 36 42
2. D.J. Anderson, and M.W. Hetzer Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum Nat. Cell Biol. 9 2007 1160 1166
3. D.J. Anderson, and M.W. Hetzer Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation J. Cell Biol. 182 2008 911 924
4. D.J. Anderson, and M.W. Hetzer Shaping the endoplasmic reticulum into the nuclear envelope J. Cell Sci. 121 2008 137 142
5. N.J. Birkbak, A.C. Eklund, Q. Li, S.E. McClelland, D. Endesfelder, P. Tan, I.B. Tan, A.L. Richardson, Z. Szallasi, and C. Swanton Paradoxical relationship between chromosomal instability and survival outcome in cancer Cancer Res. 71 2011 3447 3452
6. B. Burke, and J. Ellenberg Remodelling the walls of the nucleus Nat. Rev. Mol. Cell Biol. 3 2002 487 497
7. A. Ciccia, and S.J. Elledge The DNA damage response: making it safe to play with knives Mol. Cell 40 2010 179 204
8. D. Cimini, B. Howell, P. Maddox, A. Khodjakov, F. Degrassi, and E.D. Salmon Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells J. Cell Biol. 153 2001 517 527
9. C. Coffinier, S.Y. Chang, C. Nobumori, Y. Tu, E.A. Farber, J.I. Toth, L.G. Fong, and S.G. Young Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency Proc. Natl. Acad. Sci. USA 107 2010 5076 5081
10. K. Crasta, N.J. Ganem, R. Dagher, A.B. Lantermann, E.V. Ivanova, Y. Pan, L. Nezi, A. Protopopov, D. Chowdhury, and D. Pellman DNA breaks and chromosome pulverization from errors in mitosis Nature 482 2012 53 58
11. M. Fenech Cytokinesis-block micronucleus cytome assay Nat. Protoc. 2 2007 1084 1104
12. A.H. Fischer, K.A. Jacobson, J. Rose, and R. Zeller Paraffin embedding tissue samples for sectioning CSH Protoc. 2008 2008 pdb.prot4989-pdb.prot4989. 10.1101/pdb.prot4989
13. J.V. Forment, A. Kaidi, and S.P. Jackson Chromothripsis and cancer: causes and consequences of chromosome shattering Nat. Rev. Cancer 12 2012 663 670
14. P. Frosst, T. Guan, C. Subauste, K. Hahn, and L. Gerace Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export J. Cell Biol. 156 2002 617 630
15. T.M. Gant, and K.L. Wilson Nuclear assembly Annu. Rev. Cell Dev. Biol. 13 1997 669 695
16. M.W. Hetzer The nuclear envelope Cold Spring Harb. Perspect. Biol. 2 2010 a000539
17. D.R. Hoffelder, L. Luo, N.A. Burke, S.C. Watkins, S.M. Gollin, and W.S. Saunders Resolution of anaphase bridges in cancer cells Chromosoma 112 2004 389 397
18. N. Holland, C. Bolognesi, M. Kirsch-Volders, S. Bonassi, E. Zeiger, S. Knasmueller, and M. Fenech The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps Mutat. Res. 659 2008 93 108
19. J.-M. Lemaitre, G. Géraud, and M. Méchali Dynamics of the genome during early Xenopus laevis development: karyomeres as independent units of replication J. Cell Biol. 142 1998 1159 1166
20. M. Li, X. Fang, D.J. Baker, L. Guo, X. Gao, Z. Wei, S. Han, J.M. van Deursen, and P. Zhang The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis Proc. Natl. Acad. Sci. USA 107 2010 14188 14193
21. L. Lu, M.S. Ladinsky, and T. Kirchhausen Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly J. Cell Biol. 194 2011 425 440
22. D.R. Mackay, S.W. Elgort, and K.S. Ullman The nucleoporin Nup153 has separable roles in both early mitotic progression and the resolution of mitosis Mol. Biol. Cell 20 2009 1652 1660
23. T. Misteli, and E. Soutoglou The emerging role of nuclear architecture in DNA repair and genome maintenance Nat. Rev. Mol. Cell Biol. 10 2009 243 254
24. H. Nakamura, H. Saji, A. Idiris, N. Kawasaki, M. Hosaka, A. Ogata, T. Saijo, and H. Kato Chromosomal instability detected by fluorescence in situ hybridization in surgical specimens of non-small cell lung cancer is associated with poor survival Clin. Cancer Res. 9 2003 2294 2299
25. Z. Ni, B.E. Schwartz, J. Werner, J.-R. Suarez, and J.T. Lis Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes Mol. Cell 13 2004 55 65
26. M. Paulin-Levasseur, D.L. Blake, M. Julien, and L. Rouleau The MAN antigens are non-lamin constituents of the nuclear lamina in vertebrate cells Chromosoma 104 1996 367 379
27. E. Petermann, M.L. Orta, N. Issaeva, N. Schultz, and T. Helleday Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair Mol. Cell 37 2010 492 502
28. K. Ramadan, R. Bruderer, F.M. Spiga, O. Popp, T. Baur, M. Gotta, and H.H. Meyer Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin Nature 450 2007 1258 1262
29. T. Rausch, D.T.W. Jones, M. Zapatka, A.M. Stütz, T. Zichner, J. Weischenfeldt, N. Jäger, M. Remke, D. Shih, and P.A. Northcott Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations Cell 148 2012 59 71
30. J. Schumacher, M. Reichenzeller, T. Kempf, M. Schnölzer, and H. Herrmann Identification of a novel, highly variable amino-terminal amino acid sequence element in the nuclear intermediate filament protein lamin B(2) from higher vertebrates FEBS Lett. 580 2006 6211 6216
31. T.P. Spann, R.D. Moir, A.E. Goldman, R. Stick, and R.D. Goldman Disruption of nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis J. Cell Biol. 136 1997 1201 1212
32. T.P. Spann, A.E. Goldman, C. Wang, S. Huang, and R.D. Goldman Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription J. Cell Biol. 156 2002 603 608
33. P.J. Stephens, C.D. Greenman, B. Fu, F. Yang, G.R. Bignell, L.J. Mudie, E.D. Pleasance, K.W. Lau, D. Beare, and L.A. Stebbings Massive genomic rearrangement acquired in a single catastrophic event during cancer development Cell 144 2011 27 40
34. C.W. Tang, A. Maya-Mendoza, C. Martin, K. Zeng, S. Chen, D. Feret, S.A. Wilson, and D.A. Jackson The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells J. Cell Sci. 121 2008 1014 1024
35. M. Terradas, M. Martín, L. Tusell, and A. Genescà DNA lesions sequestered in micronuclei induce a local defective-damage response DNA Repair (Amst.) 8 2009 1225 1234
36. M. Terradas, M. Martín, L. Hernández, L. Tusell, and A. Genescà Nuclear envelope defects impede a proper response to micronuclear DNA lesions Mutat. Res. 729 2012 35 40
37. S.L. Thompson, and D.A. Compton Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors Proc. Natl. Acad. Sci. USA 108 2011 17974 17978
38. J.D. Vargas, E.M. Hatch, D.J. Anderson, and M.W. Hetzer Transient nuclear envelope rupturing during interphase in human cancer cells Nucleus 3 2012 88 100
39. L. Vergnes, M. Péterfy, M.O. Bergo, S.G. Young, and K. Reue Lamin B1 is required for mouse development and nuclear integrity Proc. Natl. Acad. Sci. USA 101 2004 10428 10433
40. G.K. Voeltz, W.A. Prinz, Y. Shibata, J.M. Rist, and T.A. Rapoport A class of membrane proteins shaping the tubular endoplasmic reticulum Cell 124 2006 573 586
41. B. Xu, Z. Sun, Z. Liu, H. Guo, Q. Liu, H. Jiang, Y. Zou, Y. Gong, J.A. Tischfield, and C. Shao Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks PLoS ONE 6 2011 e18618
42. D.J. Anderson, J.D. Vargas, J.P. Hsiao, and M.W. Hetzer Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo J. Cell Biol. 186 2009 183 191
43. K. Bodoor, S. Shaikh, D. Salina, W.H. Raharjo, R. Bastos, M. Lohka, and B. Burke Sequential recruitment of NPC proteins to the nuclear periphery at the end of mitosis J. Cell Sci. 112 1999 2253 2264
44. C.M. Doucet, J.A. Talamas, and M.W. Hetzer Cell cycle-dependent differences in nuclear pore complex assembly in metazoa Cell 141 2010 1030 1041
45. D.B. Hoffman, C.G. Pearson, T.J. Yen, B.J. Howell, and E.D. Salmon Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores Mol. Biol. Cell 12 2001 1995 2009
46. T. Kuga, N. Nozaki, K. Matsushita, F. Nomura, and T. Tomonaga Phosphorylation statuses at different residues of lamin B2, B1, and A/C dynamically and independently change throughout the cell cycle Exp. Cell Res. 316 2010 2301 2312
47. J. Pines, and T. Hunter Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B Nature 346 1990 760 763
48. M.H.A. Schmitz, M. Held, V. Janssens, J.R.A. Hutchins, O. Hudecz, E. Ivanova, J. Goris, L. Trinkle-Mulcahy, A.I. Lamond, and I. Poser Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells Nat. Cell Biol. 12 2010 886 893
49. P. Steigemann, C. Wurzenberger, M.H.A. Schmitz, M. Held, J. Guizetti, S. Maar, and D.W. Gerlich Aurora B-mediated abscission checkpoint protects against tetraploidization Cell 136 2009 473 484
50. J.D. Vargas, E.M. Hatch, D.J. Anderson, and M.W. Hetzer Transient nuclear envelope rupturing during interphase in human cancer cells Nucleus 3 2012 88 100