Stress in the kidney is the road to pERdition: Is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy?

Journal of Endocrinology

Volumn 222, Issue 3, 2014, Pages

  Zhuang, Aowen ^a   Forbes, Josephine M ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Diabetic nephropathy; Endoplasmic reticulum stress; mTORC1; Podocyte; Proximal tubule cell

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 12; CHAPERONE; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; INSULIN RECEPTOR; PROTEIN IRE1; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SODIUM GLUCOSE COTRANSPORTER 2; THIOCTIC ACID; X BOX BINDING PROTEIN 1;

APOPTOSIS; AUTOPHAGY; CELL DEATH; CYTOTOXICITY; DIABETIC NEPHROPATHY; DISEASE COURSE; ENDOPLASMIC RETICULUM STRESS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GLOMERULAR FILTRATION BARRIER; GLOMERULOPATHY; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; KIDNEY CELL; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY INJURY; LIPID STORAGE; LONG TERM EXPOSURE; METABOLIC CAPACITY; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PHYSIOLOGICAL PROCESS; PODOCYTE; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; ANIMAL; BIOLOGICAL MODEL; COMPLICATION; DIABETIC NEPHROPATHIES; DRUG EFFECTS; KIDNEY; METABOLISM; MOUSE; PATHOLOGY;

ANIMALS; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; ENDOPLASMIC RETICULUM STRESS; HUMANS; KIDNEY; MICE; MODELS, BIOLOGICAL; PODOCYTES; UNFOLDED PROTEIN RESPONSE;

EID: 84907374264     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-13-0517     Document Type: Review

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