메뉴 건너뛰기




Volumn 98, Issue 6, 1996, Pages 1481-1492

Kidney, splanchnic, and leg protein turnover in humans: Insight from leucine and phenylalanine kinetics

Author keywords

kidney; leucine kinetics; muscle; organ catheterization; splanchnic bed

Indexed keywords

LEUCINE; PHENYLALANINE;

EID: 0029744010     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118937     Document Type: Article
Times cited : (96)

References (66)
  • 2
    • 0018214611 scopus 로고
    • Carbohydrate metabolism in man. Speculation and some quantitative consideration
    • Bjorntorp, P., and L. Sjostrom. 1978. Carbohydrate metabolism in man. Speculation and some quantitative consideration. Metab. Clin. Exp. 27:1853-1863.
    • (1978) Metab. Clin. Exp. , vol.27 , pp. 1853-1863
    • Bjorntorp, P.1    Sjostrom, L.2
  • 3
    • 0024546622 scopus 로고
    • The in vivo study of cardiac and skeletal muscle protein turnover
    • Barrett, E.J., and R.A. Gelfand. 1989. The in vivo study of cardiac and skeletal muscle protein turnover. Diabetes Metab. Rev. 5:133-148.
    • (1989) Diabetes Metab. Rev. , vol.5 , pp. 133-148
    • Barrett, E.J.1    Gelfand, R.A.2
  • 4
    • 0002755273 scopus 로고
    • The proteins and amino acids
    • M.E. Shils and V.R. Young, editors. Lea & Febiger, Philadelphia
    • Munro, H.N., and M.C. Crim. 1988. The proteins and amino acids. In Modern Nutrition in Health and Disease. M.E. Shils and V.R. Young, editors. Lea & Febiger, Philadelphia. 1-37.
    • (1988) Modern Nutrition in Health and Disease , pp. 1-37
    • Munro, H.N.1    Crim, M.C.2
  • 5
    • 0027316051 scopus 로고
    • An in vitro method for the determination of protein turnover in incubated proximal tubule segments
    • May, R., B. Logue, B. Edwards, and S. Patel. 1993. An in vitro method for the determination of protein turnover in incubated proximal tubule segments. Kidney Int. 43:1156-1159.
    • (1993) Kidney Int. , vol.43 , pp. 1156-1159
    • May, R.1    Logue, B.2    Edwards, B.3    Patel, S.4
  • 6
    • 0021318982 scopus 로고
    • Protein turnover and growth in the whole body, liver and kidney of the rat from the foetus to senility
    • Goldspink, D.F., and F.J. Kelly. 1984. Protein turnover and growth in the whole body, liver and kidney of the rat from the foetus to senility. Biochem. J. 217:507-516.
    • (1984) Biochem. J. , vol.217 , pp. 507-516
    • Goldspink, D.F.1    Kelly, F.J.2
  • 7
    • 0020606967 scopus 로고
    • Consequences of renal donation in man
    • Ogden, D.A. 1983. Consequences of renal donation in man. Am. J. Kidney Dis. 2:501-511.
    • (1983) Am. J. Kidney Dis. , vol.2 , pp. 501-511
    • Ogden, D.A.1
  • 8
    • 0015856451 scopus 로고
    • Increased kidney size and glomerular filtration rate in early juvenile diabetes
    • Mogensen, C.E., and M.J.F. Andersen. 1973. Increased kidney size and glomerular filtration rate in early juvenile diabetes. Diabetes. 22:706-712.
    • (1973) Diabetes , vol.22 , pp. 706-712
    • Mogensen, C.E.1    Andersen, M.J.F.2
  • 9
    • 0018953706 scopus 로고
    • Renal metabolism of amino acids and ammonia in subjects with normal renal function and in patients with chronic renal insufficiency
    • Tizianello, A., G. Deferrari, G. Garibotto, G. Gurreri, and C. Robaudo. 1980. Renal metabolism of amino acids and ammonia in subjects with normal renal function and in patients with chronic renal insufficiency. J. Clin. Invest. 65: 1162-1173.
    • (1980) J. Clin. Invest. , vol.65 , pp. 1162-1173
    • Tizianello, A.1    Deferrari, G.2    Garibotto, G.3    Gurreri, G.4    Robaudo, C.5
  • 10
    • 0016799231 scopus 로고
    • Renal substrate exchange in human diabetes mellitus
    • Wahren, J., and P. Felig. 1975. Renal substrate exchange in human diabetes mellitus. Diabetes. 24:730-734.
    • (1975) Diabetes , vol.24 , pp. 730-734
    • Wahren, J.1    Felig, P.2
  • 13
    • 0028287003 scopus 로고
    • Whole body and splanchnic leucine, phenylalanine and glucose kinetics during endotoxemia in humans
    • Fong, Y., D.E. Matthews, W. He, M.A. Marano, L.L. Moldawer, and S.F. Lowry. 1994. Whole body and splanchnic leucine, phenylalanine and glucose kinetics during endotoxemia in humans. Am. J. Physiol. 266:R419-R425.
    • (1994) Am. J. Physiol. , vol.266
    • Fong, Y.1    Matthews, D.E.2    He, W.3    Marano, M.A.4    Moldawer, L.L.5    Lowry, S.F.6
  • 14
    • 0017083862 scopus 로고
    • Branched-chain amino acid oxidation by isolated rat tissue preparations
    • Shinnick, F.L., and A.E. Harper. 1976. Branched-chain amino acid oxidation by isolated rat tissue preparations. Biochim. Biophys. Acta. 437:477-486.
    • (1976) Biochim. Biophys. Acta. , vol.437 , pp. 477-486
    • Shinnick, F.L.1    Harper, A.E.2
  • 15
    • 0017030928 scopus 로고
    • Aspects of the regulation of the metabolism of branched chain amino acids
    • Krebs, H.A., and P. Lund. 1977. Aspects of the regulation of the metabolism of branched chain amino acids. Adv. Enzyme Regul. 15:375-394.
    • (1977) Adv. Enzyme Regul. , vol.15 , pp. 375-394
    • Krebs, H.A.1    Lund, P.2
  • 16
    • 0000564517 scopus 로고
    • Disorders of amino acid metabolism
    • P.K. Bondy and L.E. Rosenberg, editors. Saunders, Philadelphia
    • Rosenberg, L.E., and C.R. Scriver. 1980. Disorders of amino acid metabolism. In Metabolic Control and Disease. P.K. Bondy and L.E. Rosenberg, editors. Saunders, Philadelphia. 707-710.
    • (1980) Metabolic Control and Disease , pp. 707-710
    • Rosenberg, L.E.1    Scriver, C.R.2
  • 17
    • 0029073033 scopus 로고
    • Protein dynamics in whole body and in splanchnic and leg tissues in type 1 diabetic patients
    • Nair, K.S., C. Ford, K. Ekberg, E. Fernqvist-Forbes, and J. Wahren. 1995. Protein dynamics in whole body and in splanchnic and leg tissues in type 1 diabetic patients. J. Clin. Invest. 95:2926-2937.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2926-2937
    • Nair, K.S.1    Ford, C.2    Ekberg, K.3    Fernqvist-Forbes, E.4    Wahren, J.5
  • 18
    • 0003181431 scopus 로고
    • Metropolitan height and weight tables
    • Metropolitan Life Foundation. 1983. Metropolitan height and weight tables. Stat. Bull. Metrop. Life Insur. Co. 64:2-17.
    • (1983) Stat. Bull. Metrop. Life Insur. Co. , vol.64 , pp. 2-17
  • 20
    • 0024535295 scopus 로고
    • Intrinsically difficult problems: The kinetics of body proteins and amino acids in man
    • Bier, D.M. 1989. Intrinsically difficult problems: the kinetics of body proteins and amino acids in man. Diabetes Metab. Rev. 5:111-152.
    • (1989) Diabetes Metab. Rev. , vol.5 , pp. 111-152
    • Bier, D.M.1
  • 21
    • 0028122884 scopus 로고
    • Effects of insulin on whole-body and regional amino acid kinetics
    • Tessari, P. 1994. Effects of insulin on whole-body and regional amino acid kinetics. Diabetes Metab. Rev. 10:253-285.
    • (1994) Diabetes Metab. Rev. , vol.10 , pp. 253-285
    • Tessari, P.1
  • 22
    • 0024445455 scopus 로고
    • Determination of leucine and α-ketoisocaproic acid concentrations and specific activity in plasma and of leucine specific activity in proteins using high performance liquid chromatography
    • Horber, F.F., J. Kahl, L. Lecavalier, B. Krom, and M.W. Haymond. 1989. Determination of leucine and α-ketoisocaproic acid concentrations and specific activity in plasma and of leucine specific activity in proteins using high performance liquid chromatography. J. Chromatogr. 495:81-94.
    • (1989) J. Chromatogr. , vol.495 , pp. 81-94
    • Horber, F.F.1    Kahl, J.2    Lecavalier, L.3    Krom, B.4    Haymond, M.W.5
  • 23
    • 0026075779 scopus 로고
    • A fast HPLC method for the measurement of plasma concentration and specific activity of phenylalanine
    • Tessari, P., S. Inchiostro, M. Vettore, L. Sabadin, and G. Biolo. 1991. A fast HPLC method for the measurement of plasma concentration and specific activity of phenylalanine. Clin. Biochem. 24:425-428.
    • (1991) Clin. Biochem. , vol.24 , pp. 425-428
    • Tessari, P.1    Inchiostro, S.2    Vettore, M.3    Sabadin, L.4    Biolo, G.5
  • 24
    • 0021763961 scopus 로고
    • Use of t-butyldimethylsilylation in the GC/MS analysis of physiologic compounds found in plasma using electron impact ionization
    • Schwenk, W.F., P.J. Berg, B. Beaufrere, J.M. Miles, and M.W. Haymond. 1984. Use of t-butyldimethylsilylation in the GC/MS analysis of physiologic compounds found in plasma using electron impact ionization. Anal. Biochem. 141:101-109.
    • (1984) Anal. Biochem. , vol.141 , pp. 101-109
    • Schwenk, W.F.1    Berg, P.J.2    Beaufrere, B.3    Miles, J.M.4    Haymond, M.W.5
  • 25
    • 0028833354 scopus 로고
    • A model of skeletal muscle leucine kinetics measured across the human forearm
    • Tessari, P., S. Inchiostro, M. Zanetti, and R. Barazzoni. 1995. A model of skeletal muscle leucine kinetics measured across the human forearm. Am. J. Physiol. 269:E127-E136.
    • (1995) Am. J. Physiol. , vol.269
    • Tessari, P.1    Inchiostro, S.2    Zanetti, M.3    Barazzoni, R.4
  • 27
    • 0000802118 scopus 로고
    • Glucagon
    • B.M. Jaffe and H.R. Behrmann, editors. Academic Press, New York
    • Faloona, G.R., and R.H. Unger. 1985. Glucagon. In Methods in Hormone Radioimmunoassay. B.M. Jaffe and H.R. Behrmann, editors. Academic Press, New York. 317-330.
    • (1985) Methods in Hormone Radioimmunoassay , pp. 317-330
    • Faloona, G.R.1    Unger, R.H.2
  • 28
    • 84924843289 scopus 로고
    • Measurement of hepatic blood flow
    • Bradley, S.E. 1948. Measurement of hepatic blood flow. Methods Med. Res. 1:199-207.
    • (1948) Methods Med. Res. , vol.1 , pp. 199-207
    • Bradley, S.E.1
  • 29
    • 0015382336 scopus 로고
    • Net metabolism of plasma amino acids by liver and portal-drained viscera
    • Wolff, J.E., E.N. Bergman, and H.H. Williams. 1972. Net metabolism of plasma amino acids by liver and portal-drained viscera. Am. J. Physiol. 223: 438-446.
    • (1972) Am. J. Physiol. , vol.223 , pp. 438-446
    • Wolff, J.E.1    Bergman, E.N.2    Williams, H.H.3
  • 30
    • 0017278690 scopus 로고
    • Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus
    • Wahren, J., P. Felig, and L. Hagenfeldt. 1986. Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus. J. Clin. Invest. 57:987-999.
    • (1986) J. Clin. Invest. , vol.57 , pp. 987-999
    • Wahren, J.1    Felig, P.2    Hagenfeldt, L.3
  • 33
    • 0024470819 scopus 로고
    • Plasma reciprocal pool specific activity predicts that of intracellular free leucine for protein synthesis
    • Horber, F.F., C.M. Horber-Feyder, S. Krayer, W.F. Schwenk, and M.W. Haymond. 1989. Plasma reciprocal pool specific activity predicts that of intracellular free leucine for protein synthesis. Am. J. Physiol. 257:E385-E399.
    • (1989) Am. J. Physiol. , vol.257
    • Horber, F.F.1    Horber-Feyder, C.M.2    Krayer, S.3    Schwenk, W.F.4    Haymond, M.W.5
  • 34
    • 0026702573 scopus 로고
    • Stimulation of protein synthesis in pig skeletal muscle by infusion of amino acids during constant insulin availability
    • Watt, P.W., M.E. Corbett, and M.J. Rennie. 1992. Stimulation of protein synthesis in pig skeletal muscle by infusion of amino acids during constant insulin availability. Am. J. Physiol. 263:E453-E460.
    • (1992) Am. J. Physiol. , vol.263
    • Watt, P.W.1    Corbett, M.E.2    Rennie, M.J.3
  • 36
    • 0023638757 scopus 로고
    • Sample site selection for tracer studies applying a unidirectional circulatory approach
    • Layman, D.K., and R.R. Wolfe. 1987. Sample site selection for tracer studies applying a unidirectional circulatory approach. Am. J. Physiol. 253: E173-E178.
    • (1987) Am. J. Physiol. , vol.253
    • Layman, D.K.1    Wolfe, R.R.2
  • 38
    • 0025739878 scopus 로고
    • Determination of kinetic parameters of apolipoprotein B metabolism using amino acids labeled with stable isotopes
    • Parhofer, K.G., P. Hugh, R. Barrett, D.M. Bier, and G. Schonfeld. 1991. Determination of kinetic parameters of apolipoprotein B metabolism using amino acids labeled with stable isotopes. J. Lipid Res. 32:1311-1323.
    • (1991) J. Lipid Res. , vol.32 , pp. 1311-1323
    • Parhofer, K.G.1    Hugh, P.2    Barrett, R.3    Bier, D.M.4    Schonfeld, G.5
  • 39
    • 0022513837 scopus 로고
    • Direct measurement of apolipoprotein B synthesis in human very low density lipoprotein using stable isotopes and mass spectrometry
    • Cryer, D.R., T. Matsushima, J.B. Marsh, M. Yudkoff, P.M. Coates, and J.A. Cortner. 1986. Direct measurement of apolipoprotein B synthesis in human very low density lipoprotein using stable isotopes and mass spectrometry. J. Lipid Res. 27:508-516.
    • (1986) J. Lipid Res. , vol.27 , pp. 508-516
    • Cryer, D.R.1    Matsushima, T.2    Marsh, J.B.3    Yudkoff, M.4    Coates, P.M.5    Cortner, J.A.6
  • 40
    • 0027950135 scopus 로고
    • Protein synthesis and breakdown in skin and muscle: A leg model of amino acid kinetics
    • Biolo, G., A. Gastaldelli, X. Zhang, and R.R. Wolfe. 1994. Protein synthesis and breakdown in skin and muscle: a leg model of amino acid kinetics. Am. J. Physiol. 267:E467-E474.
    • (1994) Am. J. Physiol. , vol.267
    • Biolo, G.1    Gastaldelli, A.2    Zhang, X.3    Wolfe, R.R.4
  • 41
    • 0022294449 scopus 로고
    • Use of reciprocal pool specific activities to model leucine metabolism in humans
    • Schwenk, W.F., B. Beaufrere, and M.W. Haymond. 1985. Use of reciprocal pool specific activities to model leucine metabolism in humans. Am. J. Physiol. 249:E646-E650.
    • (1985) Am. J. Physiol. , vol.249
    • Schwenk, W.F.1    Beaufrere, B.2    Haymond, M.W.3
  • 44
    • 0026316130 scopus 로고
    • Proteolysis in skeletal muscle and whole body in response to euglycemic hyperinsulinemia in normal adults
    • Denne, S.C., E.A. Litchely, Y.M. Liu, G. Brechtel, and A.D. Baron. 1981. Proteolysis in skeletal muscle and whole body in response to euglycemic hyperinsulinemia in normal adults. Am. J. Physiol. 261:E809-E814.
    • (1981) Am. J. Physiol. , vol.261
    • Denne, S.C.1    Litchely, E.A.2    Liu, Y.M.3    Brechtel, G.4    Baron, A.D.5
  • 46
    • 0027518331 scopus 로고
    • Splanchnic bed utilization of leucine and phenylalanine in humans
    • Matthews, D.E., M.A. Marano, and R.G. Campbell. 1993. Splanchnic bed utilization of leucine and phenylalanine in humans. Am. J. Physiol. 264: E109-E118.
    • (1993) Am. J. Physiol. , vol.264
    • Matthews, D.E.1    Marano, M.A.2    Campbell, R.G.3
  • 47
    • 0013881117 scopus 로고
    • Transaminase of branched-chain amino acids
    • Ichihara, A., and E. Koyama. 1966. Transaminase of branched-chain amino acids. J. Biochem. 59:160-169.
    • (1966) J. Biochem. , vol.59 , pp. 160-169
    • Ichihara, A.1    Koyama, E.2
  • 48
    • 0345966540 scopus 로고
    • Renal metabolism: Relation to renal function
    • B. Brenner and F.C. Rector, editors Saunders, Philadelphia.
    • Cohen Julius, J., and E. Kamm-Donald. 1976. Renal metabolism: relation to renal function. In The Kidney. B. Brenner and F.C. Rector, editors. Saunders, Philadelphia. 126-205.
    • (1976) The Kidney , pp. 126-205
    • Cohen Julius, J.1    Kamm-Donald, E.2
  • 49
    • 0000556087 scopus 로고
    • The role of skeletal and cardiac muscle in the regulation of protein metabolism
    • H.N. Munro and J.B. Allison, editors. Academic Press, New York. Chapter 40
    • Young, V.R. 1964. The role of skeletal and cardiac muscle in the regulation of protein metabolism. In Mammalian Protein Metabolism. H.N. Munro and J.B. Allison, editors. Vol. 4. Academic Press, New York. Chapter 40:585-659.
    • (1964) Mammalian Protein Metabolism , vol.4 , pp. 585-659
    • Young, V.R.1
  • 51
    • 0002430462 scopus 로고
    • Metabolic basis of energy expenditure with particular reference to protein
    • Man. J.S. Garrow and D. Halliday, editors. John Libbey, London, Paris
    • Reeds, P.J., M.F. Fuller, and B.A. Nicholson. 1985. Metabolic basis of energy expenditure with particular reference to protein. In Substrate and Energy Metabolism in Man. J.S. Garrow and D. Halliday, editors. John Libbey, London, Paris. 45-57.
    • (1985) Substrate and Energy Metabolism , pp. 45-57
    • Reeds, P.J.1    Fuller, M.F.2    Nicholson, B.A.3
  • 52
    • 10144246608 scopus 로고
    • General composition of the animal body and its tissues
    • W.H. Freeman and Co. San Francisco. Section I, Chapter 4
    • Lloyd, L.E., B.E. McDonald, and E.W. Crampton. 1978. General composition of the animal body and its tissues. In Fundamentals of Nutrition. 2nd Ed. W.H. Freeman and Co. San Francisco. Section I, Chapter 4:36-46.
    • (1978) Fundamentals of Nutrition. 2nd Ed. , pp. 36-46
    • Lloyd, L.E.1    McDonald, B.E.2    Crampton, E.W.3
  • 53
    • 0016431403 scopus 로고
    • Renal handling of low molecular weight proteins
    • Maak, T. 1975. Renal handling of low molecular weight proteins. Am. J. Med. 58:57-64.
    • (1975) Am. J. Med. , vol.58 , pp. 57-64
    • Maak, T.1
  • 54
    • 0023897276 scopus 로고
    • Contribution of leucine to oxidative metabolism of the rat medullary thick ascending limb
    • Tring-Trang-Tan, M.M., O. Levillain, and L. Bankir. 1988. Contribution of leucine to oxidative metabolism of the rat medullary thick ascending limb. Pflügers Archiv. 411:676-680.
    • (1988) Pflügers Archiv. , vol.411 , pp. 676-680
    • Tring-Trang-Tan, M.M.1    Levillain, O.2    Bankir, L.3
  • 57
    • 0020619682 scopus 로고
    • Leucine uptake by splanchnic and leg tissues in man: Relative independence of insulin levels
    • Eriksson, L.S., L. Hagelfeldt, P. Felig, and J. Wahren. 1983. Leucine uptake by splanchnic and leg tissues in man: relative independence of insulin levels. Clin. Sci. 65:491-498.
    • (1983) Clin. Sci. , vol.65 , pp. 491-498
    • Eriksson, L.S.1    Hagelfeldt, L.2    Felig, P.3    Wahren, J.4
  • 58
    • 0025878636 scopus 로고
    • Effects of acute systemic hyperinsulinemia on forearm muscle proteolysis in healthy man
    • Tessari, P., S. Inchiostro, G. Biolo, E. Vincenti, and L. Sabadin. 1991. Effects of acute systemic hyperinsulinemia on forearm muscle proteolysis in healthy man. J. Clin. Invest. 88:27-33.
    • (1991) J. Clin. Invest. , vol.88 , pp. 27-33
    • Tessari, P.1    Inchiostro, S.2    Biolo, G.3    Vincenti, E.4    Sabadin, L.5
  • 59
    • 0023196951 scopus 로고
    • Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man
    • Gelfand, R.A., and E.J. Barrett. 1987. Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man. J. Clin. Invest. 80:1-6.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1-6
    • Gelfand, R.A.1    Barrett, E.J.2
  • 61
    • 0026636463 scopus 로고
    • Effect of hyperinsulinemia on whole body and skeletal muscle leucine carbon kinetics in humans
    • Heslin, M.J.E., E. Newman, R.F. Wolf, and P.W.T. Pisters. 1992. Effect of hyperinsulinemia on whole body and skeletal muscle leucine carbon kinetics in humans. Am. J. Physiol. 262:E911-E918.
    • (1992) Am. J. Physiol. , vol.262
    • Heslin, M.J.E.1    Newman, E.2    Wolf, R.F.3    Pisters, P.W.T.4
  • 62
    • 0000427175 scopus 로고
    • Analysis of tissues and body fluids for nitrogenous constituents
    • H.N. Munro, editor. Academic Press, New York
    • Munro, H.N., and A. Fleck. 1969. Analysis of tissues and body fluids for nitrogenous constituents. In Mammalian Protein Metabolism. H.N. Munro, editor. Academic Press, New York. 424-508.
    • (1969) Mammalian Protein Metabolism , pp. 424-508
    • Munro, H.N.1    Fleck, A.2
  • 63
    • 0017371791 scopus 로고
    • Measurement of half life of cardiac myosin heavy chain with leucyl-tRNA used as a precursor pool
    • Martin, A.F., M. Rabinowitz, R. Blough, G. Prior, and R. Zak. 1977. Measurement of half life of cardiac myosin heavy chain with leucyl-tRNA used as a precursor pool. J. Biol. Chem. 252:3422-3429.
    • (1977) J. Biol. Chem. , vol.252 , pp. 3422-3429
    • Martin, A.F.1    Rabinowitz, M.2    Blough, R.3    Prior, G.4    Zak, R.5
  • 64
    • 0014499067 scopus 로고
    • Phenylalanine hydroxylase activity in mammalian cells
    • Tourian, A., A.J. Goddart, and T.T. Puck. 1969. Phenylalanine hydroxylase activity in mammalian cells. J. Cell. Physiol. 73:159-165.
    • (1969) J. Cell. Physiol. , vol.73 , pp. 159-165
    • Tourian, A.1    Goddart, A.J.2    Puck, T.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.