Roles of type II thioesterases and their application for secondary metabolite yield improvement

Applied Microbiology and Biotechnology

Volumn 98, Issue 18, 2014, Pages 7735-7746

  Kotowska, Magdalena ^a   Pawlik, Krzysztof ^a,b  

^a INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Nonribosomal peptide synthetase; NRPS; PKS; Polyketide synthase; Synthetic biology; Type II thioesterase

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; KETONES; PEPTIDES; PLANTS (BOTANY); SUBSTRATES; SYNTHETIC BIOLOGY;

HYDROLYTIC ENZYME; NONRIBOSOMAL PEPTIDE SYNTHETASES; NRPS; POLYKETIDE SYNTHASES; SECONDARY METABOLITES; SUBSTRATE SELECTION; THIOESTERASES; YIELD IMPROVEMENT;

METABOLITES;

MONENSIN; NANCHANGMYCIN; NIGERICIN; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYKETIDE SYNTHASE; THIOL ESTER HYDROLASE; UNCLASSIFIED DRUG; FATTY ACID SYNTHASE; MULTIENZYME COMPLEX; PEPTIDE SYNTHASE; THIOESTERASE II;

AMINO ACID; CARBOXYLIC ACID; ENZYME ACTIVITY; HYDROLYSIS; PEPTIDE; PROTEIN; SECONDARY METABOLITE;

DECARBOXYLATION; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME SYNTHESIS; FATTY ACID SYNTHESIS; GENE CLUSTER; HYDROLYSIS; NONHUMAN; NONRIBOSOMAL PEPTIDE SYNTHESIS; PROTEIN DOMAIN; PROTEIN FUNCTION; SHORT SURVEY; SYNTHETIC BIOLOGY; BIOTECHNOLOGY; METABOLISM;

BIOTECHNOLOGY; FATTY ACID SYNTHASES; MULTIENZYME COMPLEXES; PEPTIDE SYNTHASES; POLYKETIDE SYNTHASES; SUBSTRATE SPECIFICITY; THIOLESTER HYDROLASES;

EID: 84906951494     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-5952-8     Document Type: Short Survey

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