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Volumn 15, Issue 5, 2008, Pages 449-458

Mechanism of Thioesterase-Catalyzed Chain Release in the Biosynthesis of the Polyether Antibiotic Nanchangmycin

Author keywords

CHEMBIO; MICROBIO

Indexed keywords

STREPTOMYCES; STREPTOMYCES NANCHANGENSIS;

EID: 43149097376     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2008.04.006     Document Type: Article
Times cited : (37)

References (29)
  • 2
    • 21244484972 scopus 로고    scopus 로고
    • Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide
    • C.C. Aldrich L. Venkatraman D.H. Sherman R.A. Fecik Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide J. Am. Chem. Soc. 127 2005 8910 8911
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 8910-8911
    • Aldrich, C.C.1    Venkatraman, L.2    Sherman, D.H.3    Fecik, R.A.4
  • 4
    • 0023584120 scopus 로고
    • Polyether biosynthesis. 3. Origin of the carbon skeleton and oxygen atoms of lenoremycin
    • D.E. Cane B.R. Hubbard Polyether biosynthesis. 3. Origin of the carbon skeleton and oxygen atoms of lenoremycin J. Am. Chem. Soc. 109 1987 6533 6535
    • (1987) J. Am. Chem. Soc. , vol.109 , pp. 6533-6535
    • Cane, D.E.1    Hubbard, B.R.2
  • 5
    • 0019839728 scopus 로고
    • Polyether biosynthesis. Origin of the oxygen atoms of monensin A
    • D.E. Cane T.-C. Liang H. Hasler Polyether biosynthesis. Origin of the oxygen atoms of monensin A J. Am. Chem. Soc. 103 1981 5962 5965
    • (1981) J. Am. Chem. Soc. , vol.103 , pp. 5962-5965
    • Cane, D.E.1    Liang, T.-C.2    Hasler, H.3
  • 6
    • 0020424744 scopus 로고
    • Polyether biosynthesis. 2. Origin of the oxygen atoms of monensin A
    • D.E. Cane T.C. Liang H. Hasler Polyether biosynthesis. 2. Origin of the oxygen atoms of monensin A J. Am. Chem. Soc. 104 1982 7274 7281
    • (1982) J. Am. Chem. Soc. , vol.104 , pp. 7274-7281
    • Cane, D.E.1    Liang, T.C.2    Hasler, H.3
  • 7
    • 0020774684 scopus 로고
    • A unified stereochemical model of polyether structure and biogenesis
    • D.E. Cane W.D. Celmer J.W. Westley A unified stereochemical model of polyether structure and biogenesis J. Am. Chem. Soc. 105 1983 3594 3600
    • (1983) J. Am. Chem. Soc. , vol.105 , pp. 3594-3600
    • Cane, D.E.1    Celmer, W.D.2    Westley, J.W.3
  • 8
    • 33748631825 scopus 로고    scopus 로고
    • Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms
    • M.A. Fischbach C.T. Walsh Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms Chem. Rev. 106 2006 3468 3496
    • (2006) Chem. Rev. , vol.106 , pp. 3468-3496
    • Fischbach, M.A.1    Walsh, C.T.2
  • 10
    • 0031019131 scopus 로고    scopus 로고
    • Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds
    • C. Gumila M.L. Ancelin A.M. Delort G. Jeminet H.J. Vial Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds Antimicrob. Agents Chemother. 41 1997 523 529
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 523-529
    • Gumila, C.1    Ancelin, M.L.2    Delort, A.M.3    Jeminet, G.4    Vial, H.J.5
  • 11
    • 0037452723 scopus 로고    scopus 로고
    • PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
    • B. Gust G.L. Challis K. Fowler T. Kieser K.F. Chater PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin Proc. Natl. Acad. Sci. USA 100 2003 1541 1546
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1541-1546
    • Gust, B.1    Challis, G.L.2    Fowler, K.3    Kieser, T.4    Chater, K.F.5
  • 13
    • 34250309503 scopus 로고    scopus 로고
    • Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137
    • B.M. Harvey T. Mironenko Y. Sun H. Hong Z. Deng P.F. Leadlay K.J. Weissman S.F. Haydock Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137 Chem. Biol. 14 2007 703 714
    • (2007) Chem. Biol. , vol.14 , pp. 703-714
    • Harvey, B.M.1    Mironenko, T.2    Sun, Y.3    Hong, H.4    Deng, Z.5    Leadlay, P.F.6    Weissman, K.J.7    Haydock, S.F.8
  • 14
    • 28044470997 scopus 로고    scopus 로고
    • Macrolactonization to 10-deoxymethynolide catalyzed by the recombinant thioesterase of the picromycin/methymycin polyketide synthase
    • W. He J. Wu C. Khosla D.E. Cane Macrolactonization to 10-deoxymethynolide catalyzed by the recombinant thioesterase of the picromycin/methymycin polyketide synthase Bioorg. Med. Chem. Lett. 16 2006 391 394
    • (2006) Bioorg. Med. Chem. Lett. , vol.16 , pp. 391-394
    • He, W.1    Wu, J.2    Khosla, C.3    Cane, D.E.4
  • 17
    • 33748528639 scopus 로고    scopus 로고
    • Identification of NanE as the thioesterase for polyether chain release in nanchangmycin biosynthesis
    • T. Liu D. You C. Valenzano Y. Sun J. Li Q. Yu X. Zhou D.E. Cane Z. Deng Identification of NanE as the thioesterase for polyether chain release in nanchangmycin biosynthesis Chem. Biol. 13 2006 945 955
    • (2006) Chem. Biol. , vol.13 , pp. 945-955
    • Liu, T.1    You, D.2    Valenzano, C.3    Sun, Y.4    Li, J.5    Yu, Q.6    Zhou, X.7    Cane, D.E.8    Deng, Z.9
  • 18
    • 0037159192 scopus 로고    scopus 로고
    • Expression, site-directed mutagenesis, and steady state kinetic analysis of the terminal thioesterase domain of the methymycin/picromycin polyketide synthase
    • H. Lu S.C. Tsai C. Khosla D.E. Cane Expression, site-directed mutagenesis, and steady state kinetic analysis of the terminal thioesterase domain of the methymycin/picromycin polyketide synthase Biochemistry 41 2002 12590 12597
    • (2002) Biochemistry , vol.41 , pp. 12590-12597
    • Lu, H.1    Tsai, S.C.2    Khosla, C.3    Cane, D.E.4
  • 20
    • 0141789847 scopus 로고    scopus 로고
    • Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization
    • M. Oliynyk C.B. Stark A. Bhatt M.A. Jones Z.A. Hughes-Thomas C. Wilkinson Z. Oliynyk Y. Demydchuk J. Staunton P.F. Leadlay Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization Mol. Microbiol. 49 2003 1179 1190
    • (2003) Mol. Microbiol. , vol.49 , pp. 1179-1190
    • Oliynyk, M.1    Stark, C.B.2    Bhatt, A.3    Jones, M.A.4    Hughes-Thomas, Z.A.5    Wilkinson, C.6    Oliynyk, Z.7    Demydchuk, Y.8    Staunton, J.9    Leadlay, P.F.10
  • 24
    • 0036175076 scopus 로고    scopus 로고
    • ‘Streptomyces nanchangensis’, a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters
    • Y. Sun X. Zhou J. Liu K. Bao G. Zhang G. Tu T. Kieser Z. Deng ‘ Streptomyces nanchangensis ’, a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters Microbiology 148 2002 361 371
    • (2002) Microbiology , vol.148 , pp. 361-371
    • Sun, Y.1    Zhou, X.2    Liu, J.3    Bao, K.4    Zhang, G.5    Tu, G.6    Kieser, T.7    Deng, Z.8
  • 25
    • 0037846116 scopus 로고    scopus 로고
    • A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin
    • Y. Sun X. Zhou H. Dong G. Tu M. Wang B. Wang Z. Deng A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin Chem. Biol. 10 2003 431 441
    • (2003) Chem. Biol. , vol.10 , pp. 431-441
    • Sun, Y.1    Zhou, X.2    Dong, H.3    Tu, G.4    Wang, M.5    Wang, B.6    Deng, Z.7
  • 27
    • 0037159232 scopus 로고    scopus 로고
    • Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases
    • S.-C. Tsai H. Lu D.E. Cane C. Khosla R.M. Stroud Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry 41 2002 12598 12606
    • (2002) Biochemistry , vol.41 , pp. 12598-12606
    • Tsai, S.-C.1    Lu, H.2    Cane, D.E.3    Khosla, C.4    Stroud, R.M.5
  • 28
    • 0035957047 scopus 로고    scopus 로고
    • Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules
    • S.Y. Tsuji D.E. Cane C. Khosla Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules Biochemistry 40 2001 2326 2331
    • (2001) Biochemistry , vol.40 , pp. 2326-2331
    • Tsuji, S.Y.1    Cane, D.E.2    Khosla, C.3
  • 29
    • 0032483753 scopus 로고    scopus 로고
    • Total synthesis of (+)-amphidinolide J
    • D.R. Williams W.S. Kissel Total synthesis of (+)-amphidinolide J J. Am. Chem. Soc. 120 1998 11198 11199
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 11198-11199
    • Williams, D.R.1    Kissel, W.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.