The acyltransferase homologue from the initiation module of the R1128 polyketide synthase is an Acyl-ACP thioesterase that edits acetyl primer units

Biochemistry

Volumn 43, Issue 29, 2004, Pages 9546-9555

  Tang, Yi ^a,c   Koppisch, Andrew T ^a   Khosla, Chaitan ^a,b  

^a Stanford University   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BIOSYNTHESIS; ENZYME KINETICS; ENZYMES;

ACYL CARRIER PROTEINS (ACP); DECARBOXYLATION;

BIOCHEMISTRY;

ACETIC ACID; ACETIC ACID DERIVATIVE; ACETYL ACYL CARRIER PROTEIN; ACETYL COENZYME A; ACYL CARRIER PROTEIN; ACYL CARRIER PROTEIN THIOESTERASE; ACYLTRANSFERASE; DOXORUBICIN; HEXANOYL ACETYL COENZYME A; HEXANOYL ACYL CARRIER PROTEIN; KETOSYNTHASE 3; MALONYL ACYL CARRIER PROTEIN; OCTANOYL ACYL CARRIER PROTEIN; POLYKETIDE SYNTHASE; PROPIONYL ACYL CARRIER PROTEIN; PROTEIN ZHUC; TETRACENOMYCIN C; THIOL ESTER HYDROLASE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CATALYSIS; DECARBOXYLATION; ENZYME MECHANISM; IN VIVO STUDY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN MODIFICATION; SEQUENCE HOMOLOGY;

ACYLATION; CATALYSIS; HYDROLYSIS; MULTIENZYME COMPLEXES; THIOLESTER HYDROLASES;

EID: 3242738305     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049157k     Document Type: Article

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