Biochemical and genetic insights into asukamycin biosynthesis

Journal of Biological Chemistry

Volumn 285, Issue 32, 2010, Pages 24915-24924

  Rui, Zhe ^a   Petříčková, Kateřina ^b   Škanta, František ^b   Pospíšil, Stanislav ^b   Yang, Yanling ^a   Chen, Chung Yung ^c   Tsai, Shih Feng ^d   Floss, Heinz G ^e   Petříček, Miroslav ^b   Yu, Tin Wein ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL AGENTS; BACTERIA; BIOCHEMISTRY; BIOSYNTHESIS; CLONING; DRUG PRODUCTS; GENES; KETONES; METABOLITES;

3-AMINO-4-HYDROXYBENZOIC ACIDS; BIOINFORMATIC ANALYSIS; BIOSYNTHETIC GENE CLUSTER; BIOSYNTHETIC PATHWAY; CELLULAR FATTY ACIDS; CELLULAR MEMBRANES; POLYKETIDE SYNTHASES; STREPTOMYCES LIVIDANS;

FATTY ACIDS;

2 AMINO 3 HYDROXYCYCLOPENT 2 ENONE; 3 AMINO 4 HYDROXYBENZOIC ACID; 4 HYDROXYPROTOASUKAMYCIN; ACYL COENZYME A; ASUKAMYCIN; BACTERIAL PROTEIN; BENZOIC ACID DERIVATIVE; CHEMICAL COMPOUND; CYCLOHEXANE; FATTY ACID SYNTHASE; ISOLEUCINE; LEUCINE; NATURAL PRODUCT; POLYKETIDE; POLYKETIDE SYNTHASE; POLYKETIDE SYNTHASE III; PROTEIN ASUA; PROTEIN ASUB; PROTEIN ASUC; PROTEIN ASUC15; PROTEIN ASUC3; PROTEIN ASUC4; PROTEIN ASUD; PROTEIN ASUE1; PROTEIN ASUE2; PROTEIN ASUE3; PROTEIN FABH; PROTOASUKAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALINE; ANTINEOPLASTIC AGENT; FATTY ACID; POLYENE;

ARTICLE; BIOCHEMISTRY; BIOSYNTHESIS; CELL MEMBRANE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HOMEOSTASIS; MOLECULAR CLONING; MOLECULAR GENETICS; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOMYCES LIVIDANS; BIOLOGICAL MODEL; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; DRUG DESIGN; ENZYMOLOGY; GENETIC RECOMBINATION; MEDICINAL CHEMISTRY; METABOLISM; MULTIGENE FAMILY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPEN READING FRAME; PROCEDURES; STREPTOMYCES;

ANTINEOPLASTIC AGENTS; CATALYSIS; CHEMISTRY, PHARMACEUTICAL; CLONING, MOLECULAR; DRUG DESIGN; FATTY ACID SYNTHASES; FATTY ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, GENETIC; MULTIGENE FAMILY; OPEN READING FRAMES; POLYENES; RECOMBINATION, GENETIC; STREPTOMYCES;

EID: 77955301196     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.128850     Document Type: Article

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