메뉴 건너뛰기




Volumn 220, Issue , 2014, Pages 283-307

Neurotrophins and the regulation of energy balance and body weight

Author keywords

BDNF; CNTF; Dopamine; Energy balance; Energy expenditure; Food intake; GDNF; Hindbrain; Hypothalamus; Mesolimbic; Neurotrophins; NT 4; Obesity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CILIARY NEUROTROPHIC FACTOR; DOPAMINE; GHRELIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MELANOCORTIN; NERVE GROWTH FACTOR; NEUROPEPTIDE Y; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN 4; PROOPIOMELANOCORTIN; BRAIN DERIVED NEUROTROPHIC FACTOR;

EID: 84906544487     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-642-45106-5_11     Document Type: Article
Times cited : (19)

References (142)
  • 1
    • 78650190642 scopus 로고    scopus 로고
    • Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism
    • Akkermann K, Hiio K, Villa I, Harro J (2011) Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism. Psychiatry Res 185:39–43
    • (2011) Psychiatry Res , vol.185 , pp. 39-43
    • Akkermann, K.1    Hiio, K.2    Villa, I.3    Harro, J.4
  • 3
    • 84964125510 scopus 로고
    • Localization of a “feeding center” in the hypothalamus of the rat
    • Anand BK, Brobeck JR (1951) Localization of a “feeding center” in the hypothalamus of the rat. Proc Soc Exp Biol Med 77:323–324
    • (1951) Proc Soc Exp Biol Med , vol.77 , pp. 323-324
    • Anand, B.K.1    Brobeck, J.R.2
  • 5
    • 0034526219 scopus 로고    scopus 로고
    • Single or continuous injection of glial cell line-derived neurotrophic factor in the striatum induces recovery of the nigrostriatal dopaminergic system
    • Aoi M, Date I, Tomita S, Ohmoto T (2000) Single or continuous injection of glial cell line-derived neurotrophic factor in the striatum induces recovery of the nigrostriatal dopaminergic system. Neurol Res 22:832–836
    • (2000) Neurol Res , vol.22 , pp. 832-836
    • Aoi, M.1    Date, I.2    Tomita, S.3    Ohmoto, T.4
  • 6
    • 0842330416 scopus 로고    scopus 로고
    • Activation of a subpopulation of orexin/hypocretin-containing hypothalamic neurons by GABAA receptormediated inhibition of the nucleus accumbens shell, but not by exposure to a novel environment
    • Baldo BA, Gual-Bonilla L, Sijapati K, Daniel RA, Landry CF, Kelley AE (2004) Activation of a subpopulation of orexin/hypocretin-containing hypothalamic neurons by GABAA receptormediated inhibition of the nucleus accumbens shell, but not by exposure to a novel environment. Eur J Neurosci 19:376–386
    • (2004) Eur J Neurosci , vol.19 , pp. 376-386
    • Baldo, B.A.1    Gual-Bonilla, L.2    Sijapati, K.3    Daniel, R.A.4    Landry, C.F.5    Kelley, A.E.6
  • 7
    • 21544446985 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta
    • Baquet ZC, Bickford PC, Jones KR (2005) Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta. J Neurosci 25:6251–6259
    • (2005) J Neurosci , vol.25 , pp. 6251-6259
    • Baquet, Z.C.1    Bickford, P.C.2    Jones, K.R.3
  • 8
    • 27844512893 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor plays a role as an anorexigenic factor in the dorsal vagal complex
    • Bariohay B, Lebrun B, Moyse E, Jean A (2005) Brain-derived neurotrophic factor plays a role as an anorexigenic factor in the dorsal vagal complex. Endocrinology 146:5612–5620
    • (2005) Endocrinology , vol.146 , pp. 5612-5620
    • Bariohay, B.1    Lebrun, B.2    Moyse, E.3    Jean, A.4
  • 9
    • 66649122305 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor/tropomyosin-related kinase receptor type B signaling is a downstream effector of the brainstem melanocortin system in food intake control
    • Bariohay B, Roux J, Tardivel C, Trouslard J, Jean A, Lebrun B (2009) Brain-derived neurotrophic factor/tropomyosin-related kinase receptor type B signaling is a downstream effector of the brainstem melanocortin system in food intake control. Endocrinology 150:2646–2653
    • (2009) Endocrinology , vol.150 , pp. 2646-2653
    • Bariohay, B.1    Roux, J.2    Tardivel, C.3    Trouslard, J.4    Jean, A.5    Lebrun, B.6
  • 10
    • 0031021193 scopus 로고    scopus 로고
    • Differential influence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum
    • Bassareo V, Di Chiara G (1997) Differential influence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum. J Neurosci 17:851–861
    • (1997) J Neurosci , vol.17 , pp. 851-861
    • Bassareo, V.1    Di Chiara, G.2
  • 11
    • 0033406776 scopus 로고    scopus 로고
    • Modulation of feeding-induced activation of mesolimbic dopamine transmission by appetitive stimuli and its relation to motivational state
    • Bassareo V, Di Chiara G (1999) Modulation of feeding-induced activation of mesolimbic dopamine transmission by appetitive stimuli and its relation to motivational state. Eur J Neurosci 11:4389–4397
    • (1999) Eur J Neurosci , vol.11 , pp. 4389-4397
    • Bassareo, V.1    Di Chiara, G.2
  • 12
    • 0036616876 scopus 로고    scopus 로고
    • Differential expression of motivational stimulus properties by dopamine in nucleus accumbens shell versus core and prefrontal cortex
    • Bassareo V, De Luca MA, Di Chiara G (2002) Differential expression of motivational stimulus properties by dopamine in nucleus accumbens shell versus core and prefrontal cortex. J Neurosci 22:4709–4719
    • (2002) J Neurosci , vol.22 , pp. 4709-4719
    • Bassareo, V.1    De Luca, M.A.2    Di Chiara, G.3
  • 15
    • 68649118810 scopus 로고    scopus 로고
    • Liking and ‘wanting’ food rewards: Brain substrates and roles in eating disorders
    • Berridge KC (2009) ‘Liking’ and ‘wanting’ food rewards: brain substrates and roles in eating disorders. Physiol Behav 97:537–550
    • (2009) Physiol Behav , vol.97 , pp. 537-550
    • Berridge, K.C.1
  • 16
    • 7444253376 scopus 로고    scopus 로고
    • Neural control of appetite: Cross-talk between homeostatic and non-homeostatic systems
    • Berthoud HR (2004) Neural control of appetite: cross-talk between homeostatic and non-homeostatic systems. Appetite 43:315–317
    • (2004) Appetite , vol.43 , pp. 315-317
    • Berthoud, H.R.1
  • 17
    • 0033963072 scopus 로고    scopus 로고
    • Dopaminergic agonists normalize elevated hypothalamic neuropeptide Y and corticotropin-releasing hormone, body weight gain, and hyperglycemia in ob/ob mice
    • Bina KG, Cincotta AH (2000) Dopaminergic agonists normalize elevated hypothalamic neuropeptide Y and corticotropin-releasing hormone, body weight gain, and hyperglycemia in ob/ob mice. Neuroendocrinology 71:68–78
    • (2000) Neuroendocrinology , vol.71 , pp. 68-78
    • Bina, K.G.1    Cincotta, A.H.2
  • 18
    • 0026766094 scopus 로고
    • The melanin-concentrating hormone system of the rat brain: An immuno- and hybridization histochemical characterization
    • Bittencourt JC, Presse F, Arias C, Peto C, Vaughan J, Nahon JL, Vale W, Sawchenko PE (1992) The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J Comp Neurol 319:218–245
    • (1992) J Comp Neurol , vol.319 , pp. 218-245
    • Bittencourt, J.C.1    Presse, F.2    Arias, C.3    Peto, C.4    Vaughan, J.5    Nahon, J.L.6    Vale, W.7    Sawchenko, P.E.8
  • 20
    • 33747191480 scopus 로고    scopus 로고
    • High-fat hyperphagia in neurotrophin-4 deficient mice reveals potential role of vagal intestinal sensory innervation in long-term controls of food intake
    • Byerly MS, Fox EA (2006) High-fat hyperphagia in neurotrophin-4 deficient mice reveals potential role of vagal intestinal sensory innervation in long-term controls of food intake. Neurosci Lett 400:240–245
    • (2006) Neurosci Lett , vol.400 , pp. 240-245
    • Byerly, M.S.1    Fox, E.A.2
  • 21
    • 0028133318 scopus 로고
    • Organization of projections from the ventromedial nucleus of the hypothalamus: A Phaseolus vulgaris-leucoagglutinin study in the rat
    • Canteras NS, Simerly RB, Swanson LW (1994) Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat. J Comp Neurol 348:41–79
    • (1994) J Comp Neurol , vol.348 , pp. 41-79
    • Canteras, N.S.1    Simerly, R.B.2    Swanson, L.W.3
  • 22
    • 80052739107 scopus 로고    scopus 로고
    • White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamicadipocyte axis
    • Cao L, Choi EY, Liu X, Martin A, Wang C, Xu X, During MJ (2011) White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamicadipocyte axis. Cell Metab 14:324–338
    • (2011) Cell Metab , vol.14 , pp. 324-338
    • Cao, L.1    Choi, E.Y.2    Liu, X.3    Martin, A.4    Wang, C.5    Xu, X.6    During, M.J.7
  • 23
    • 0037083578 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure
    • Carter AR, Chen C, Schwartz PM, Segal RA (2002) Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. J Neurosci 22:1316–1327
    • (2002) J Neurosci , vol.22 , pp. 1316-1327
    • Carter, A.R.1    Chen, C.2    Schwartz, P.M.3    Segal, R.A.4
  • 25
    • 34447526711 scopus 로고    scopus 로고
    • NT-4-deficient mice lack sensitivity to meal-associated preabsorptive feedback from lipids
    • Chi MM, Powley TL (2007) NT-4-deficient mice lack sensitivity to meal-associated preabsorptive feedback from lipids. Am J Physiol Regul Integr Comp Physiol 292:R2124–R2135
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , pp. 2124-2135
    • Chi, M.M.1    Powley, T.L.2
  • 27
    • 0031004888 scopus 로고    scopus 로고
    • Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: Evidence for anterograde axonal transport
    • Conner JM, Lauterborn JC, Yan Q, Gall CM, Varon S (1997) Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J Neurosci 17:2295–2313
    • (1997) J Neurosci , vol.17 , pp. 2295-2313
    • Conner, J.M.1    Lauterborn, J.C.2    Yan, Q.3    Gall, C.M.4    Varon, S.5
  • 28
    • 11144241044 scopus 로고    scopus 로고
    • Control of hyperphagia prevents obesity in BDNF heterozygous mice
    • Coppola V, Tessarollo L (2004) Control of hyperphagia prevents obesity in BDNF heterozygous mice. Neuroreport 15:2665–2668
    • (2004) Neuroreport , vol.15 , pp. 2665-2668
    • Coppola, V.1    Tessarollo, L.2
  • 29
    • 77249134520 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system
    • Cordeira JW, Frank L, Sena-Esteves M, Pothos EN, Rios M (2010) Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system. J Neurosci 30: 2533–2541
    • (2010) J Neurosci , vol.30 , pp. 2533-2541
    • Cordeira, J.W.1    Frank, L.2    Sena-Esteves, M.3    Pothos, E.N.4    Rios, M.5
  • 32
    • 70350774226 scopus 로고    scopus 로고
    • Feeding signals and brain circuitry
    • Dietrich MO, Horvath TL (2009) Feeding signals and brain circuitry. Eur J Neurosci 30: 1688–1696
    • (2009) Eur J Neurosci , vol.30 , pp. 1688-1696
    • Dietrich, M.O.1    Horvath, T.L.2
  • 34
    • 0034038168 scopus 로고    scopus 로고
    • Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities
    • Fan G, Egles C, Sun Y, Minichiello L, Renger JJ, Klein R, Liu G, Jaenisch R (2000) Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nat Neurosci 3:350–357
    • (2000) Nat Neurosci , vol.3 , pp. 350-357
    • Fan, G.1    Egles, C.2    Sun, Y.3    Minichiello, L.4    Renger, J.J.5    Klein, R.6    Liu, G.7    Jaenisch, R.8
  • 35
    • 1842560331 scopus 로고    scopus 로고
    • Cholecystokininmediated suppression of feeding involves the brainstem melanocortin system
    • Fan W, Ellacott KL, Halatchev IG, Takahashi K, Yu P, Cone RD (2004) Cholecystokininmediated suppression of feeding involves the brainstem melanocortin system. Nat Neurosci 7:335–336
    • (2004) Nat Neurosci , vol.7 , pp. 335-336
    • Fan, W.1    Ellacott, K.L.2    Halatchev, I.G.3    Takahashi, K.4    Yu, P.5    Cone, R.D.6
  • 38
    • 2442663015 scopus 로고    scopus 로고
    • A mechanism underlying mature-onset obesity: Evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants
    • Fox EA, Byerly MS (2004) A mechanism underlying mature-onset obesity: evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants. Am J Physiol Regul Integr Comp Physiol 286:R994–R1004
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286 , pp. 994-1004
    • Fox, E.A.1    Byerly, M.S.2
  • 39
    • 0035503048 scopus 로고    scopus 로고
    • Neurotrophin-4 deficient mice have a loss of vagal intraganglionic mechanoreceptors from the small intestine and a disruption of short-term satiety
    • Fox EA, Phillips RJ, Baronowsky EA, Byerly MS, Jones S, Powley TL (2001) Neurotrophin-4 deficient mice have a loss of vagal intraganglionic mechanoreceptors from the small intestine and a disruption of short-term satiety. J Neurosci 21:8602–8615
    • (2001) J Neurosci , vol.21 , pp. 8602-8615
    • Fox, E.A.1    Phillips, R.J.2    Baronowsky, E.A.3    Byerly, M.S.4    Jones, S.5    Powley, T.L.6
  • 40
    • 0345073736 scopus 로고    scopus 로고
    • Tyrosine kinase B and C receptors in the neostriatum and nucleus accumbens are co-localized in enkephalin-positive and enkephalinnegative neuronal profiles and their expression is influenced by cocaine
    • Freeman AY, Soghomonian JJ, Pierce RC (2003) Tyrosine kinase B and C receptors in the neostriatum and nucleus accumbens are co-localized in enkephalin-positive and enkephalinnegative neuronal profiles and their expression is influenced by cocaine. Neuroscience 117:147–156
    • (2003) Neuroscience , vol.117 , pp. 147-156
    • Freeman, A.Y.1    Soghomonian, J.J.2    Pierce, R.C.3
  • 47
    • 0031963436 scopus 로고    scopus 로고
    • Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus
    • Hakansson ML, Brown H, Ghilardi N, Skoda RC, Meister B (1998) Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus. J Neurosci 18:559–572
    • (1998) J Neurosci , vol.18 , pp. 559-572
    • Hakansson, M.L.1    Brown, H.2    Ghilardi, N.3    Skoda, R.C.4    Meister, B.5
  • 49
    • 39149129347 scopus 로고    scopus 로고
    • Autoradiographic analysis of ghrelin receptors in the rat hypothalamus
    • Harrold JA, Dovey T, Cai XJ, Halford JC, Pinkney J (2008) Autoradiographic analysis of ghrelin receptors in the rat hypothalamus. Brain Res 1196:59–64
    • (2008) Brain Res , vol.1196 , pp. 59-64
    • Harrold, J.A.1    Dovey, T.2    Cai, X.J.3    Halford, J.C.4    Pinkney, J.5
  • 50
    • 0025411637 scopus 로고
    • From dietary restraint to binge eating: Attaching causes to effects
    • discussion 142–123
    • Herman CP, Polivy J (1990) From dietary restraint to binge eating: attaching causes to effects. Appetite 14:123–125, discussion 142–123
    • (1990) Appetite , vol.14 , pp. 123-125
    • Herman, C.P.1    Polivy, J.2
  • 51
    • 0023946717 scopus 로고
    • Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis
    • Hernandez L, Hoebel BG (1988) Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life Sci 42:1705–1712
    • (1988) Life Sci , vol.42 , pp. 1705-1712
    • Hernandez, L.1    Hoebel, B.G.2
  • 52
    • 0032751734 scopus 로고    scopus 로고
    • Differential in vivo effects of neurturin and glial cell-line-derived neurotrophic factor
    • Hoane MR, Gulwadi AG, Morrison S, Hovanesian G, Lindner MD, Tao W (1999) Differential in vivo effects of neurturin and glial cell-line-derived neurotrophic factor. Exp Neurol 160: 235–243
    • (1999) Exp Neurol , vol.160 , pp. 235-243
    • Hoane, M.R.1    Gulwadi, A.G.2    Morrison, S.3    Hovanesian, G.4    Lindner, M.D.5    Tao, W.6
  • 53
    • 0033799293 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression
    • Hock C, Heese K, Muller-Spahn F, Huber P, Riesen W, Nitsch RM, Otten U (2000) Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression. Mol Psychiatry 5:510–513
    • (2000) Mol Psychiatry , vol.5 , pp. 510-513
    • Hock, C.1    Heese, K.2    Muller-Spahn, F.3    Huber, P.4    Riesen, W.5    Nitsch, R.M.6    Otten, U.7
  • 55
    • 0029940555 scopus 로고    scopus 로고
    • The neurotrophins and CNTF: Two families of collaborative neurotrophic factors
    • Ip NY, Yancopoulos GD (1996) The neurotrophins and CNTF: two families of collaborative neurotrophic factors. Annu Rev Neurosci 19:491–515
    • (1996) Annu Rev Neurosci , vol.19 , pp. 491-515
    • Ip, N.Y.1    Yancopoulos, G.D.2
  • 56
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • Kernie SG, Liebl DJ, Parada LF (2000) BDNF regulates eating behavior and locomotor activity in mice. EMBO J 19:1290–1300
    • (2000) EMBO J , vol.19 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 57
    • 27344441682 scopus 로고    scopus 로고
    • Neurogenesis in the hypothalamus of adult mice: potential role in energy balance
    • Kokoeva MV, Yin H, Flier JS (2005) Neurogenesis in the hypothalamus of adult mice: potential role in energy balance. Science 310:679–683
    • (2005) Science , vol.310 , pp. 679-683
    • Kokoeva, M.V.1    Yin, H.2    Flier, J.S.3
  • 58
    • 33646139871 scopus 로고    scopus 로고
    • Induction of brain-derived neurotrophic factor by leptin in the ventromedial hypothalamus
    • Komori T, Morikawa Y, Nanjo K, Senba E (2006) Induction of brain-derived neurotrophic factor by leptin in the ventromedial hypothalamus. Neuroscience 139:1107–1115
    • (2006) Neuroscience , vol.139 , pp. 1107-1115
    • Komori, T.1    Morikawa, Y.2    Nanjo, K.3    Senba, E.4
  • 59
    • 0029021177 scopus 로고
    • Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
    • Korte M, Carroll P, Wolf E, Brem G, Thoenen H, Bonhoeffer T (1995) Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A 92:8856–8860
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8856-8860
    • Korte, M.1    Carroll, P.2    Wolf, E.3    Brem, G.4    Thoenen, H.5    Bonhoeffer, T.6
  • 61
    • 46349095132 scopus 로고    scopus 로고
    • Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice
    • Kublaoui BM, Gemelli T, Tolson KP, Wang Y, Zinn AR (2008) Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice. Mol Endocrinol 22:1723–1734
    • (2008) Mol Endocrinol , vol.22 , pp. 1723-1734
    • Kublaoui, B.M.1    Gemelli, T.2    Tolson, K.P.3    Wang, Y.4    Zinn, A.R.5
  • 63
    • 0032903415 scopus 로고    scopus 로고
    • Effects of osmotic pressure and brain-derived neurotrophic factor on the survival of postnatal hypothalamic oxytocinergic and vasopressinergic neurons in dissociated cell culture
    • Kusano K, House SB, Gainer H (1999) Effects of osmotic pressure and brain-derived neurotrophic factor on the survival of postnatal hypothalamic oxytocinergic and vasopressinergic neurons in dissociated cell culture. J Neuroendocrinol 11:145–152
    • (1999) J Neuroendocrinol , vol.11 , pp. 145-152
    • Kusano, K.1    House, S.B.2    Gainer, H.3
  • 64
    • 0026625201 scopus 로고
    • BDNF and NGF treatment in lesioned rats: Effects on cholinergic function and weight gain
    • Lapchak PA, Hefti F (1992) BDNF and NGF treatment in lesioned rats: effects on cholinergic function and weight gain. Neuroreport 3:405–408
    • (1992) Neuroreport , vol.3 , pp. 405-408
    • Lapchak, P.A.1    Hefti, F.2
  • 65
    • 0031589698 scopus 로고    scopus 로고
    • Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson’s disease
    • Lapchak PA, Araujo DM, Hilt DC, Sheng J, Jiao S (1997) Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson’s disease. Brain Res 777:153–160
    • (1997) Brain Res , vol.777 , pp. 153-160
    • Lapchak, P.A.1    Araujo, D.M.2    Hilt, D.C.3    Sheng, J.4    Jiao, S.5
  • 66
    • 0027481601 scopus 로고
    • Associated factors for self-reported binge eating among male and female adolescents
    • Ledoux S, Choquet M, Manfredi R (1993) Associated factors for self-reported binge eating among male and female adolescents. J Adolesc 16:75–91
    • (1993) J Adolesc , vol.16 , pp. 75-91
    • Ledoux, S.1    Choquet, M.2    Manfredi, R.3
  • 68
    • 0032848721 scopus 로고    scopus 로고
    • Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived neurotrophic functions
    • Lommatzsch M, Braun A, Mannsfeldt A, Botchkarev VA, Botchkareva NV, Paus R, Fischer A, Lewin GR, Renz H (1999) Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived neurotrophic functions. Am J Pathol 155:1183–1193
    • (1999) Am J Pathol , vol.155 , pp. 1183-1193
    • Lommatzsch, M.1    Braun, A.2    Mannsfeldt, A.3    Botchkarev, V.A.4    Botchkareva, N.V.5    Paus, R.6    Fischer, A.7    Lewin, G.R.8    Renz, H.9
  • 69
    • 0018830458 scopus 로고
    • Interrelations between lateral, dorsomedial and ventromedial hypothalamic nuclei in the rat. An HRP study
    • Luiten PG, Room P (1980) Interrelations between lateral, dorsomedial and ventromedial hypothalamic nuclei in the rat. An HRP study. Brain Res 190:321–332
    • (1980) Brain Res , vol.190 , pp. 321-332
    • Luiten, P.G.1    Room, P.2
  • 71
    • 0030045757 scopus 로고    scopus 로고
    • Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system
    • MacLennan AJ, Vinson EN, Marks L, McLaurin DL, Pfeifer M, Lee N (1996) Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system. J Neurosci 16:621–630
    • (1996) J Neurosci , vol.16 , pp. 621-630
    • Maclennan, A.J.1    Vinson, E.N.2    Marks, L.3    McLaurin, D.L.4    Pfeifer, M.5    Lee, N.6
  • 73
    • 0028265181 scopus 로고
    • Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: Interactions with amphetamine
    • Martin-Iverson MT, Todd KG, Altar CA (1994) Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine. J Neurosci 14:1262–1270
    • (1994) J Neurosci , vol.14 , pp. 1262-1270
    • Martin-Iverson, M.T.1    Todd, K.G.2    Altar, C.A.3
  • 74
    • 0031470983 scopus 로고    scopus 로고
    • Synergy between leptin and cholecystokinin (CCK) to control daily caloric intake
    • Matson CA, Wiater MF, Kuijper JL, Weigle DS (1997) Synergy between leptin and cholecystokinin (CCK) to control daily caloric intake. Peptides 18:1275–1278
    • (1997) Peptides , vol.18 , pp. 1275-1278
    • Matson, C.A.1    Wiater, M.F.2    Kuijper, J.L.3    Weigle, D.S.4
  • 75
    • 0030920912 scopus 로고    scopus 로고
    • Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth
    • McAllister AK, Katz LC, Lo DC (1997) Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron 18:767–778
    • (1997) Neuron , vol.18 , pp. 767-778
    • McAllister, A.K.1    Katz, L.C.2    Lo, D.C.3
  • 77
    • 33747785881 scopus 로고    scopus 로고
    • The 196G/A (Val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder
    • Monteleone P, Zanardini R, Tortorella A, Gennarelli M, Castaldo E, Canestrelli B, Maj M (2006) The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder. Neurosci Lett 406:133–137
    • (2006) Neurosci Lett , vol.406 , pp. 133-137
    • Monteleone, P.1    Zanardini, R.2    Tortorella, A.3    Gennarelli, M.4    Castaldo, E.5    Canestrelli, B.6    Maj, M.7
  • 78
    • 79951720709 scopus 로고    scopus 로고
    • In vitro functionality of isolated embryonic hypothalamic vasopressinergic and oxytocinergic neurons: Modulatory effects of brain-derived neurotrophic factor and angiotensin II
    • Moreno G, Piermaria J, Gaillard RC, Spinedi E (2011) In vitro functionality of isolated embryonic hypothalamic vasopressinergic and oxytocinergic neurons: modulatory effects of brain-derived neurotrophic factor and angiotensin II. Endocrine 39:83–88
    • (2011) Endocrine , vol.39 , pp. 83-88
    • Moreno, G.1    Piermaria, J.2    Gaillard, R.C.3    Spinedi, E.4
  • 80
    • 36248944567 scopus 로고    scopus 로고
    • Melanocortin-4 receptor activation stimulates hypothalamic brain-derived neurotrophic factor release to regulate food intake, body temperature and cardiovascular function
    • Nicholson JR, Peter JC, Lecourt AC, Barde YA, Hofbauer KG (2007) Melanocortin-4 receptor activation stimulates hypothalamic brain-derived neurotrophic factor release to regulate food intake, body temperature and cardiovascular function. J Neuroendocrinol 19:974–982
    • (2007) J Neuroendocrinol , vol.19 , pp. 974-982
    • Nicholson, J.R.1    Peter, J.C.2    Lecourt, A.C.3    Barde, Y.A.4    Hofbauer, K.G.5
  • 81
    • 0035200051 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor regulates energy expenditure through the central nervous system in obese diabetic mice
    • Nonomura T, Tsuchida A, Ono-Kishino M, Nakagawa T, Taiji M, Noguchi H (2001) Brainderived neurotrophic factor regulates energy expenditure through the central nervous system in obese diabetic mice. Int J Exp Diabetes Res 2:201–209
    • (2001) Int J Exp Diabetes Res , vol.2 , pp. 201-209
    • Nonomura, T.1    Tsuchida, A.2    Ono-Kishino, M.3    Nakagawa, T.4    Taiji, M.5    Noguchi, H.6
  • 82
    • 0033579839 scopus 로고    scopus 로고
    • Expression of trkB and trkC mRNAs by adult midbrain dopamine neurons: A double-label in situ hybridization study
    • Numan S, Seroogy KB (1999) Expression of trkB and trkC mRNAs by adult midbrain dopamine neurons: a double-label in situ hybridization study. J Comp Neurol 403:295–308
    • (1999) J Comp Neurol , vol.403 , pp. 295-308
    • Numan, S.1    Seroogy, K.B.2
  • 83
    • 0032535430 scopus 로고    scopus 로고
    • Differential regulation of neurotrophin and trk receptor mRNAs in catecholaminergic nuclei during chronic opiate treatment and withdrawal
    • Numan S, Lane-Ladd SB, Zhang L, Lundgren KH, Russell DS, Seroogy KB, Nestler EJ (1998) Differential regulation of neurotrophin and trk receptor mRNAs in catecholaminergic nuclei during chronic opiate treatment and withdrawal. J Neurosci 18:10700–10708
    • (1998) J Neurosci , vol.18 , pp. 10700-10708
    • Numan, S.1    Lane-Ladd, S.B.2    Zhang, L.3    Lundgren, K.H.4    Russell, D.S.5    Seroogy, K.B.6    Nestler, E.J.7
  • 84
    • 0026486342 scopus 로고
    • Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum
    • Okazawa H, Murata M, Watanabe M, Kamei M, Kanazawa I (1992) Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum. FEBS Lett 313:138–142
    • (1992) FEBS Lett , vol.313 , pp. 138-142
    • Okazawa, H.1    Murata, M.2    Watanabe, M.3    Kamei, M.4    Kanazawa, I.5
  • 85
    • 82855175142 scopus 로고    scopus 로고
    • A food restriction protocol that increases drug reward decreases tropomyosin receptor kinase B in the ventral tegmental area, with no effect on brain-derived neurotrophic factor or tropomyosin receptor kinase B protein levels in dopaminergic forebrain regions
    • Pan Y, Chau L, Liu S, Avshalumov MV, Rice ME, Carr KD (2011) A food restriction protocol that increases drug reward decreases tropomyosin receptor kinase B in the ventral tegmental area, with no effect on brain-derived neurotrophic factor or tropomyosin receptor kinase B protein levels in dopaminergic forebrain regions. Neuroscience 197:330–338
    • (2011) Neuroscience , vol.197 , pp. 330-338
    • Pan, Y.1    Chau, L.2    Liu, S.3    Avshalumov, M.V.4    Rice, M.E.5    Carr, K.D.6
  • 86
    • 0035369840 scopus 로고    scopus 로고
    • Trk receptors: Mediators of neurotrophin action
    • Patapoutian A, Reichardt LF (2001) Trk receptors: mediators of neurotrophin action. Curr Opin Neurobiol 11:272–280
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 272-280
    • Patapoutian, A.1    Reichardt, L.F.2
  • 88
    • 0020823798 scopus 로고
    • Endocrine basis for weight gain after fasting or VMH lesion in rats
    • Penicaud L, Larue-Achagiotis C, Le Magnen J (1983) Endocrine basis for weight gain after fasting or VMH lesion in rats. Am J Physiol 245:E246–E252
    • (1983) Am J Physiol , vol.245 , pp. 246-252
    • Penicaud, L.1    Larue-Achagiotis, C.2    Le Magnen, J.3
  • 91
    • 0028824239 scopus 로고
    • Restricted eating with weight loss selectively decreases extracellular dopamine in the nucleus accumbens and alters dopamine response to amphetamine, morphine, and food intake
    • Pothos EN, Creese I, Hoebel BG (1995a) Restricted eating with weight loss selectively decreases extracellular dopamine in the nucleus accumbens and alters dopamine response to amphetamine, morphine, and food intake. J Neurosci 15:6640–6650
    • (1995) J Neurosci , vol.15 , pp. 6640-6650
    • Pothos, E.N.1    Creese, I.2    Hoebel, B.G.3
  • 92
    • 0029400286 scopus 로고
    • Chronic food deprivation decreases extracellular dopamine in the nucleus accumbens: Implications for a possible neurochemical link between weight loss and drug abuse
    • Pothos EN, Hernandez L, Hoebel BG (1995b) Chronic food deprivation decreases extracellular dopamine in the nucleus accumbens: implications for a possible neurochemical link between weight loss and drug abuse. Obes Res 3(Suppl 4):525S–529S
    • (1995) Obes Res , vol.3 , pp. 525-529
    • Pothos, E.N.1    Hernandez, L.2    Hoebel, B.G.3
  • 93
    • 33745740035 scopus 로고    scopus 로고
    • BDNF-dependent synaptic sensitization in midbrain dopamine neurons after cocaine withdrawal
    • Pu L, Liu QS, Poo MM (2006) BDNF-dependent synaptic sensitization in midbrain dopamine neurons after cocaine withdrawal. Nat Neurosci 9:605–607
    • (2006) Nat Neurosci , vol.9 , pp. 605-607
    • Pu, L.1    Liu, Q.S.2    Poo, M.M.3
  • 94
    • 23644445840 scopus 로고    scopus 로고
    • Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell
    • Rada P, Avena NM, Hoebel BG (2005) Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell. Neuroscience 134:737–744
    • (2005) Neuroscience , vol.134 , pp. 737-744
    • Rada, P.1    Avena, N.M.2    Hoebel, B.G.3
  • 95
    • 13644266295 scopus 로고    scopus 로고
    • The mesolimbic dopaminergic response to novel palatable food consumption increases dopamine-D1 receptor-mediated signalling with complex modifications of the DARPP-32 phosphorylation pattern
    • Rauggi R, Scheggi S, Cassanelli A, De Montis MG, Tagliamonte A, Gambarana C (2005) The mesolimbic dopaminergic response to novel palatable food consumption increases dopamine-D1 receptor-mediated signalling with complex modifications of the DARPP-32 phosphorylation pattern. J Neurochem 92:867–877
    • (2005) J Neurochem , vol.92 , pp. 867-877
    • Rauggi, R.1    Scheggi, S.2    Cassanelli, A.3    De Montis, M.G.4    Tagliamonte, A.5    Gambarana, C.6
  • 96
    • 33749010358 scopus 로고    scopus 로고
    • Neurotrophin-regulated signalling pathways
    • Reichardt LF (2006) Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 361:1545–1564
    • (2006) Philos Trans R Soc Lond B Biol Sci , vol.361 , pp. 1545-1564
    • Reichardt, L.F.1
  • 97
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM, Jaenisch R (2001) Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 15:1748–1757
    • (2001) Mol Endocrinol , vol.15 , pp. 1748-1757
    • Rios, M.1    Fan, G.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 98
    • 0018790626 scopus 로고
    • An autoradiographic study of the efferent connections of the lateral hypothalamic area in the rat
    • Saper CB, Swanson LW, Cowan WM (1979) An autoradiographic study of the efferent connections of the lateral hypothalamic area in the rat. J Comp Neurol 183:689–706
    • (1979) J Comp Neurol , vol.183 , pp. 689-706
    • Saper, C.B.1    Swanson, L.W.2    Cowan, W.M.3
  • 99
    • 0033780625 scopus 로고    scopus 로고
    • The role of gastrointestinal vagal afferents in the control of food intake: Current prospects
    • Schwartz GJ (2000) The role of gastrointestinal vagal afferents in the control of food intake: current prospects. Nutrition 16:866–873
    • (2000) Nutrition , vol.16 , pp. 866-873
    • Schwartz, G.J.1
  • 103
    • 1842486891 scopus 로고    scopus 로고
    • Ethnic difference of the BDNF 196G/A (Val66met) polymorphism frequencies: The possibility to explain ethnic mental traits
    • Shimizu E, Hashimoto K, Iyo M (2004) Ethnic difference of the BDNF 196G/A (val66met) polymorphism frequencies: the possibility to explain ethnic mental traits. Am J Med Genet B Neuropsychiatr Genet 126:122–123
    • (2004) Am J Med Genet B Neuropsychiatr Genet , vol.126 , pp. 122-123
    • Shimizu, E.1    Hashimoto, K.2    Iyo, M.3
  • 104
    • 67649406272 scopus 로고    scopus 로고
    • Hypothalamic regulation of food intake and clinical therapeutic applications
    • Simpson KA, Martin NM, Bloom SR (2009) Hypothalamic regulation of food intake and clinical therapeutic applications. Arq Bras Endocrinol Metabol 53:120–128
    • (2009) Arq Bras Endocrinol Metabol , vol.53 , pp. 120-128
    • Simpson, K.A.1    Martin, N.M.2    Bloom, S.R.3
  • 108
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH ! arcuate nucleus microcircuits and their reorganization by fasting
    • Sternson SM, Shepherd GM, Friedman JM (2005) Topographic mapping of VMH ! arcuate nucleus microcircuits and their reorganization by fasting. Nat Neurosci 8:1356–1363
    • (2005) Nat Neurosci , vol.8 , pp. 1356-1363
    • Sternson, S.M.1    Shepherd, G.M.2    Friedman, J.M.3
  • 109
    • 56849092405 scopus 로고    scopus 로고
    • Relation of reward from food intake and anticipated food intake to obesity: A functional magnetic resonance imaging study
    • Stice E, Spoor S, Bohon C, Veldhuizen MG, Small DM (2008) Relation of reward from food intake and anticipated food intake to obesity: a functional magnetic resonance imaging study. J Abnorm Psychol 117:924–935
    • (2008) J Abnorm Psychol , vol.117 , pp. 924-935
    • Stice, E.1    Spoor, S.2    Bohon, C.3    Veldhuizen, M.G.4    Small, D.M.5
  • 110
    • 0038411327 scopus 로고    scopus 로고
    • Temporal changes in the expression of brain-derived neurotrophic factor mRNA in the ventromedial nucleus of the hypothalamus of the developing rat brain
    • Sugiyama N, Kanba S, Arita J (2003) Temporal changes in the expression of brain-derived neurotrophic factor mRNA in the ventromedial nucleus of the hypothalamus of the developing rat brain. Brain Res Mol Brain Res 115:69–77
    • (2003) Brain Res Mol Brain Res , vol.115 , pp. 69-77
    • Sugiyama, N.1    Kanba, S.2    Arita, J.3
  • 111
    • 55349106519 scopus 로고    scopus 로고
    • Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet
    • Teegarden SL, Nestler EJ, Bale TL (2008) Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet. Biol Psychiatry 64:941–950
    • (2008) Biol Psychiatry , vol.64 , pp. 941-950
    • Teegarden, S.L.1    Nestler, E.J.2    Bale, T.L.3
  • 113
    • 0027765548 scopus 로고
    • Neuroendocrine regulation of thyrotropin-releasing hormone (TRH) in the tuberoinfundibular system
    • Toni R, Lechan RM (1993) Neuroendocrine regulation of thyrotropin-releasing hormone (TRH) in the tuberoinfundibular system. J Endocrinol Invest 16:715–753
    • (1993) J Endocrinol Invest , vol.16 , pp. 715-753
    • Toni, R.1    Lechan, R.M.2
  • 114
    • 0033005143 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor improves blood glucose control and alleviates fasting hyperglycemia in C57BLKS-Lepr(Db)/lepr(db) mice
    • Tonra JR, Ono M, Liu X, Garcia K, Jackson C, Yancopoulos GD, Wiegand SJ, Wong V (1999) Brain-derived neurotrophic factor improves blood glucose control and alleviates fasting hyperglycemia in C57BLKS-Lepr(db)/lepr(db) mice. Diabetes 48:588–594
    • (1999) Diabetes , vol.48 , pp. 588-594
    • Tonra, J.R.1    Ono, M.2    Liu, X.3    Garcia, K.4    Jackson, C.5    Yancopoulos, G.D.6    Wiegand, S.J.7    Wong, V.8
  • 115
    • 77956005564 scopus 로고    scopus 로고
    • Long-term infusion of brain-derived neurotrophic factor reduces food intake and body weight via a corticotrophin-releasing hormone pathway in the paraventricular nucleus of the hypothalamus
    • Toriya M, Maekawa F, Maejima Y, Onaka T, Fujiwara K, Nakagawa T, Nakata M, Yada T (2010) Long-term infusion of brain-derived neurotrophic factor reduces food intake and body weight via a corticotrophin-releasing hormone pathway in the paraventricular nucleus of the hypothalamus. J Neuroendocrinol 22:987–995
    • (2010) J Neuroendocrinol , vol.22 , pp. 987-995
    • Toriya, M.1    Maekawa, F.2    Maejima, Y.3    Onaka, T.4    Fujiwara, K.5    Nakagawa, T.6    Nakata, M.7    Yada, T.8
  • 117
    • 33748454310 scopus 로고    scopus 로고
    • Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage
    • Tran PV, Akana SF, Malkovska I, Dallman MF, Parada LF, Ingraham HA (2006) Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage. J Comp Neurol 498:637–648
    • (2006) J Comp Neurol , vol.498 , pp. 637-648
    • Tran, P.V.1    Akana, S.F.2    Malkovska, I.3    Dallman, M.F.4    Parada, L.F.5    Ingraham, H.A.6
  • 122
    • 37549055474 scopus 로고    scopus 로고
    • Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity
    • Unger TJ, Calderon GA, Bradley LC, Sena-Esteves M, Rios M (2007) Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. J Neurosci 27:14265–14274
    • (2007) J Neurosci , vol.27 , pp. 14265-14274
    • Unger, T.J.1    Calderon, G.A.2    Bradley, L.C.3    Sena-Esteves, M.4    Rios, M.5
  • 123
    • 0033927916 scopus 로고    scopus 로고
    • Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
    • Vaisse C, Clement K, Durand E, Hercberg S, Guy-Grand B, Froguel P (2000) Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J Clin Invest 106:253–262
    • (2000) J Clin Invest , vol.106 , pp. 253-262
    • Vaisse, C.1    Clement, K.2    Durand, E.3    Hercberg, S.4    Guy-Grand, B.5    Froguel, P.6
  • 124
    • 34548451564 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rate
    • Wang C, Bomberg E, Billington C, Levine A, Kotz CM (2007a) Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rate. Am J Physiol Regul Integr Comp Physiol 293(3):R992–R1002
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293 , Issue.3 , pp. 992-1002
    • Wang, C.1    Bomberg, E.2    Billington, C.3    Levine, A.4    Kotz, C.M.5
  • 125
    • 34548381683 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reduces energy intake
    • Wang C, Bomberg E, Billington C, Levine A, Kotz CM (2007b) Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reduces energy intake. Am J Physiol Regul Integr Comp Physiol 293:R1003–R1012
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293 , pp. 1003-1012
    • Wang, C.1    Bomberg, E.2    Billington, C.3    Levine, A.4    Kotz, C.M.5
  • 126
    • 34548462036 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in the ventromedial nucleus of the hypothalamus reduces energy intake
    • Wang C, Bomberg E, Levine A, Billington C, Kotz CM (2007c) Brain-derived neurotrophic factor in the ventromedial nucleus of the hypothalamus reduces energy intake. Am J Physiol Regul Integr Comp Physiol 293:R1037–R1045
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293 , pp. 1037-1045
    • Wang, C.1    Bomberg, E.2    Levine, A.3    Billington, C.4    Kotz, C.M.5
  • 127
    • 77952243631 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure
    • Wang C, Bomberg E, Billington CJ, Levine AS, Kotz CM (2010a) Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure. Brain Res 1336:66–77
    • (2010) Brain Res , vol.1336 , pp. 66-77
    • Wang, C.1    Bomberg, E.2    Billington, C.J.3    Levine, A.S.4    Kotz, C.M.5
  • 128
    • 77951743757 scopus 로고    scopus 로고
    • Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet
    • Wang C, Godar RJ, Billington CJ, Kotz CM (2010b) Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet. Am J Physiol Regul Integr Comp Physiol 298:R1320–R1332
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298 , pp. 1320-1332
    • Wang, C.1    Godar, R.J.2    Billington, C.J.3    Kotz, C.M.4
  • 131
    • 0025816941 scopus 로고
    • Hypophagia is induced by intracerebroventricular administration of nerve growth factor
    • Williams LR (1991) Hypophagia is induced by intracerebroventricular administration of nerve growth factor. Exp Neurol 113:31–37
    • (1991) Exp Neurol , vol.113 , pp. 31-37
    • Williams, L.R.1
  • 132
    • 0034456725 scopus 로고    scopus 로고
    • The role of the dorsal vagal complex and the vagus nerve in feeding effects of melanocortin-3/4 receptor stimulation
    • Williams DL, Kaplan JM, Grill HJ (2000) The role of the dorsal vagal complex and the vagus nerve in feeding effects of melanocortin-3/4 receptor stimulation. Endocrinology 141: 1332–1337
    • (2000) Endocrinology , vol.141 , pp. 1332-1337
    • Williams, D.L.1    Kaplan, J.M.2    Grill, H.J.3
  • 133
    • 70449635660 scopus 로고    scopus 로고
    • Hindbrain leptin receptor stimulation enhances the anorexic response to cholecystokinin
    • Williams DL, Baskin DG, Schwartz MW (2009) Hindbrain leptin receptor stimulation enhances the anorexic response to cholecystokinin. Am J Physiol Regul Integr Comp Physiol 297: R1238–R1246
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297 , pp. 1238-1246
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 134
    • 0031788012 scopus 로고    scopus 로고
    • Anorectic effects of the cytokine, ciliary neurotropic factor, are mediated by hypothalamic neuropeptide Y: Comparison with leptin
    • Xu B, Dube MG, Kalra PS, Farmerie WG, Kaibara A, Moldawer LL, Martin D, Kalra SP (1998) Anorectic effects of the cytokine, ciliary neurotropic factor, are mediated by hypothalamic neuropeptide Y: comparison with leptin. Endocrinology 139:466–473
    • (1998) Endocrinology , vol.139 , pp. 466-473
    • Xu, B.1    Dube, M.G.2    Kalra, P.S.3    Farmerie, W.G.4    Kaibara, A.5    Moldawer, L.L.6    Martin, D.7    Kalra, S.P.8
  • 136
    • 33845867730 scopus 로고    scopus 로고
    • Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding
    • Xu AW, Ste-Marie L, Kaelin CB, Barsh GS (2007) Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding. Endocrinology 148:72–80
    • (2007) Endocrinology , vol.148 , pp. 72-80
    • Xu, A.W.1    Ste-Marie, L.2    Kaelin, C.B.3    Barsh, G.S.4
  • 138
    • 0035706917 scopus 로고    scopus 로고
    • GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons
    • Yang F, Feng L, Zheng F, Johnson SW, Du J, Shen L, Wu CP, Lu B (2001) GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons. Nat Neurosci 4:1071–1078
    • (2001) Nat Neurosci , vol.4 , pp. 1071-1078
    • Yang, F.1    Feng, L.2    Zheng, F.3    Johnson, S.W.4    Du, J.5    Shen, L.6    Wu, C.P.7    Lu, B.8
  • 140
    • 0022453435 scopus 로고
    • Distribution of immunoreactive melaninconcentrating hormone in the central nervous system of the rat
    • Zamir N, Skofitsch G, Jacobowitz DM (1986) Distribution of immunoreactive melaninconcentrating hormone in the central nervous system of the rat. Brain Res 373:240–245
    • (1986) Brain Res , vol.373 , pp. 240-245
    • Zamir, N.1    Skofitsch, G.2    Jacobowitz, D.M.3
  • 141
    • 0038521147 scopus 로고    scopus 로고
    • Peptides that regulate food intake: Appetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons
    • Zheng H, Corkern M, Stoyanova I, Patterson LM, Tian R, Berthoud HR (2003) Peptides that regulate food intake: appetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons. Am J Physiol Regul Integr Comp Physiol 284: R1436–R1444
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284 , pp. 1436-1444
    • Zheng, H.1    Corkern, M.2    Stoyanova, I.3    Patterson, L.M.4    Tian, R.5    Berthoud, H.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.