Neurogenesis in the hypothalamus of adult mice: Potential role in energy balance

Science

Volumn 310, Issue 5748, 2005, Pages 679-683

  Kokoeva, Maia V ^a   Yin, Huali ^a   Flier, Jeffrey S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DISEASES; GENETIC ENGINEERING; NEUROLOGY; TRANSDUCERS;

CILIARY NEUROTROPHIC FACTOR (CNTF); ENERGY-BALANCE CONTROL; HYPOTHALAMIC NEUROGENESIS; SIGNAL TRANSDUCER;

GENES;

BETA TUBULIN; BROXURIDINE; CYTARABINE; DNA; DOUBLECORTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; LEPTIN; MESSENGER RNA; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; RECOMBINANT CILIARY NEUROTROPHIC FACTOR; STAT3 PROTEIN;

NEUROLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; DIETARY INTAKE; ENERGY BALANCE; FAT INTAKE; FEEDING BEHAVIOR; GENE EXPRESSION; GLIA CELL; HYPOTHALAMUS; IN SITU HYBRIDIZATION; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; OBESITY; OSMOTIC MINIPUMP; PHENOTYPE; PRIORITY JOURNAL; TREATMENT OUTCOME; WEIGHT REDUCTION;

ANIMALS; BODY WEIGHT; BROMODEOXYURIDINE; CELL PROLIFERATION; CILIARY NEUROTROPHIC FACTOR; CYTARABINE; ENERGY METABOLISM; HYPOTHALAMUS; INJECTIONS, INTRAVENTRICULAR; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; NEUROPEPTIDE Y; NEUROPEPTIDES; PRO-OPIOMELANOCORTIN; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR;

ANIMALIA; ARA; MURINAE; RODENTIA;

EID: 27344441682     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1115360     Document Type: Article

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41. We thank J. K. Elmquist, C. A. Walsh, V. L. Sheen and R. H. Friedel for critical reading of the manuscript and helpful comments; A. C. Budde for help with the gold thioglucose experiment; and K.-F. Storch for many valuable discussions during the course of this work. Confocal microscope analyses were carried out at the Harvard Center for Neurodegeneration and Repair. This work was supported by grant DKR3728082 from the NIH (J.S.F.).