Ethnic Difference of the BDNF 196G/A (val66met) Polymorphism Frequencies: The Possibility to Explain Ethnic Mental Traits [2]

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 126 B, Issue 1, 2004, Pages 122-123

  Shimizu, Eiji ^a   Hashimoto, Kenji ^a   Iyo, Masaomi ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; METHIONINE; VALINE;

ALLELE; DNA POLYMORPHISM; ETHNOLOGY; GENOTYPE; HOMOZYGOSITY; HUMAN; ITALY; JAPAN; LETTER; MENTAL FUNCTION; PERSONALITY; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; UNITED STATES;

ALZHEIMER DISEASE; BRAIN-DERIVED NEUROTROPHIC FACTOR; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ITALY; JAPAN; POLYMORPHISM, GENETIC; UNITED STATES;

EID: 1842486891     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: None     Document Type: Letter

References (6)

1. Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, Zaitsev E, Gold B, Goldman D, Dean M, Lu B, Weinberger DR. 2003. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112:257-269.
2. Itoh K, Hashimoto K, Kumakiri C, Shimizu E, Iyo M. Association between brain-derived neurotrophic factor 196 A/G polymorphism and personality traits in healthy subjects. Am J Med Genet (Neuropsychiatr Genet) (in press).
3. Kumakiri C, Kodama K, Shimizu E, Yamanouchi N, Okada S, Noda S, Okamoto H, Sato T, Shirasawa H. 1999. Study of the association between the serotonin transporter gene regulatory region polymorphism and personality traits in a Japanese population. Neurosci Lett 263:205-207.
4. Mossner R, Daniel S, Albert D, Heils A, Okladnova O, Schmitt A, Lesch KP. 2000. Serotonin transporter function is modulated by brain-derived neurotrophic factor (BDNF) but not nerve growth factor (NGF). Neurochem Int 36:197-202.
5. Suh GH, Shah A. 2001. A review of the epidemiological transition in dementia-Cross-national comparisons of the indices related to Alzheimer's disease and vascular dementia. Acta Psychiatr Scand 104:4-11.
6. Ventriglia M, Bocchio Chiavetto L, Benussi L, Binetti G, Zanetti O, Riva MA, Gennarelli M. 2002. Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease. Mol Psychiatry 7:136-137.