Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure

Journal of Neuroscience

Volumn 22, Issue 4, 2002, Pages 1316-1327

  Carter, Alexandre R ^a   Chen, Chinfei ^b   Schwartz, Phillip M ^a   Segal, Rosalind A ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

BDNF; Cerebellum; Facilitation; Neurotrophin; Presynaptic plasticity; Trk receptor; Ultrastructure

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NEUROTROPHIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL SURVIVAL; CEREBELLUM; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; FACILITATION; FEMALE; GENE DELETION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MOUSE MUTANT; NERVE CELL PLASTICITY; NEWBORN; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PURKINJE CELL; SYNAPSE; SYNAPSE VESICLE; ULTRASTRUCTURE;

EID: 0037083578     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-04-01316.2002     Document Type: Article

References (66)

1. Delayed release of neurotransmitter from cerebellar granule cells
2. Synaptic reliability correlates with reduced susceptibility to synaptic potentiation by brain-derived neurotrophic factor
3. The synaptic vesicle cycle
4. Regulation of hippocampal transmitter release during development and long-term potentiation
5. Myosin Va movements in normal and dilute-lethal axons provide support for a dual filament motor complex
6. Neurotrophin release by neurotrophins: Implications for activity-dependent neuronal plasticity
7. The mechanism of cAMP-mediated enhancement at a cerebellar synapse
8. The effect on synaptic physiology of synaptotagmin mutations in Drosophila
9. Heterogeneity of release probability, facilitation, and depletion at central synapses
10. The actin cytoskeleton and neurotransmitter release: An overview
11. Mice lacking brain-derived neurotrophic factor develop with sensory deficits
12. Subcellular localization of myosin V in nerve growth cones and outgrowth from dilute-lethal neurons
13. Genetics of synaptic vesicle function: Toward the complete functional anatomy of an organelle
14. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
15. Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampus
16. BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons
17. Synapsins as regulators of neurotransmitter release
18. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
19. Membrane fusion and exocytosis
20. Use-dependent decline of paired-pulse facilitation at Aplysia sensory neuron synapses suggests a distinct vesicle pool or release mechanism
21. Neurotrophin-evoked rapid excitation through TrkB receptors
22. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus
23. Neurotrophin-induced modulation of synaptic transmission in the adult hippocampus
24. The role of calcium in neuromuscular facilitation
25. Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system
26. Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
27. Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice
28. The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments
29. Modulation of transmission during trains at a cerebellar synapse
30. Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells
31. Griscelli syndrome: Rare neonatal syndrome of recurrent hemophagocytosis
32. Differential localization of δ glutamate receptors in the rat cerebellum: Coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses
33. BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones
34. Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors
35. Genetic evidence for an equilibrium between docked and undocked vesicles
36. Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons
37. Neurotrophins and hippocampal synaptic transmission and plasticity
38. Role of neurotrophins in synapse development and plasticity
39. Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors
40. Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate
41. TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections
42. Neurotrophins and synaptic plasticity
43. Granule neuron regulation of Purkinje cell development: Striking a balance between neurotrophin and glutamate signaling
44. Heterogeneous release properties of visualized individual hippocampal synapses
45. Neurotrophin-elicited short-term glutamate release from cultured cerebellar granule neurons
46. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
47. Distinct pools of synaptic vesicles in neurotransmitter release
48. Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knock-out mice
49. Brain myosin V is a synaptic vesicle-associated motor protein: Evidence for a Ca2+-dependent interaction with the synaptobrevin-synaptophysin complex
50. Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila
51. Short-term synaptic plasticity is altered in mice lacking synapsin I
52. Definition of the readily releasable pool of vesicles at hippocampal synapses
53. Control of neurotransmitter release by presynaptic waveform at the granule cell to Purkinje cell synapse
54. Quantitative fine-structural analysis of olfactory cortical synapses
55. Changes in paired-pulse facilitation suggest presynaptic involvement in long-term potentiation
56. Neurotrophin regulation of synaptic transmission
57. Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning
58. Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells
59. TrkB signaling modulates spine density and morphology independent of dendrite structure in cultured neonatal Purkinje cells
60. Synaptic modulation by neurotrophic factors: Differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor
61. The synaptic vesicle cycle: A cascade of protein-protein interactions
62. The synaptic vesicle cycle revisited
63. Synapsin I deficiency results in the structural change in the presynaptic terminals in the murine nervous system
64. BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses
65. Increased exocytotic capability of rat cerebellar granule neurons cultured under depolarizing conditions
66. Short-term synaptic plasticity