Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity

Molecular Metabolism

Volumn 3, Issue 6, 2014, Pages 608-618

  Pedroso, João A B ^a   Buonfiglio, Daniella C ^a   Cardinali, Lais I ^a   Furigo, Isadora C ^a   Ramos Lobo, Angela M ^a   Tirapegui, Julio ^a   Elias, Carol F ^b,c,d   Donato, Jose ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

High fat diet; Hypothalamus; Leptin resistance; POMC; Suppressor of cytokine signaling 3; Type 2 diabetes mellitus

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CRE RECOMBINASE; LEPTIN; LEPTIN RECEPTOR; NESTIN; PROOPIOMELANOCORTIN; PROTEIN C FOS; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; GENE EXPRESSION; GENETIC RECOMBINATION; GLUCOSE HOMEOSTASIS; GLYCEMIC CONTROL; HYPOTHALAMUS; INSULIN RESISTANCE; MALE; MOUSE; MOUSE MODEL; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOCS3 GENE; TRANSGENE;

MUS;

EID: 84906275240     PISSN: 22128778     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmet.2014.06.001     Document Type: Article

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