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Volumn 18, Issue 1, 2013, Pages 21-28

Metabolic pitfalls of CNS cre-based technology

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CRE RECOMBINASE; NESTIN; NEUROGENIN 3; NEUROPEPTIDE Y; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA;

EID: 84879868603     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.05.019     Document Type: Review
Times cited : (166)

References (63)
  • 5
    • 5444275097 scopus 로고    scopus 로고
    • Immune responses to gene therapy vectors: Influence on vector function and effector mechanisms
    • N. Bessis, F.J. GarciaCozar, and M.C. Boissier Immune responses to gene therapy vectors: influence on vector function and effector mechanisms Gene Ther. 11 Suppl 1 2004 S10 S17
    • (2004) Gene Ther. , vol.11 , Issue.SUPPL. 1
    • Bessis, N.1    Garciacozar, F.J.2    Boissier, M.C.3
  • 6
    • 0346503889 scopus 로고    scopus 로고
    • Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice
    • C.S. Branda, and S.M. Dymecki Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice Dev. Cell 6 2004 7 28
    • (2004) Dev. Cell , vol.6 , pp. 7-28
    • Branda, C.S.1    Dymecki, S.M.2
  • 7
    • 78650071301 scopus 로고    scopus 로고
    • Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance
    • N. Briancon, D.E. McNay, E. Maratos-Flier, and J.S. Flier Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance Diabetes 59 2010 3074 3084
    • (2010) Diabetes , vol.59 , pp. 3074-3084
    • Briancon, N.1    McNay, D.E.2    Maratos-Flier, E.3    Flier, J.S.4
  • 8
    • 84919691300 scopus 로고    scopus 로고
    • Transgenesis
    • J.M. Walker, R. Rapley, Royal Society of Chemistry Cambridge
    • E.J. Cartwright, and X. Wang Transgenesis J.M. Walker, R. Rapley, Molecular Biology and Biotechnology 2009 Royal Society of Chemistry Cambridge 390 491
    • (2009) Molecular Biology and Biotechnology , pp. 390-491
    • Cartwright, E.J.1    Wang, X.2
  • 9
    • 0019855228 scopus 로고
    • Introduction of a rabbit beta-globin gene into the mouse germ line
    • F. Costantini, and E. Lacy Introduction of a rabbit beta-globin gene into the mouse germ line Nature 294 1981 92 94
    • (1981) Nature , vol.294 , pp. 92-94
    • Costantini, F.1    Lacy, E.2
  • 11
    • 84861326894 scopus 로고    scopus 로고
    • The advent of AAV9 expands applications for brain and spinal cord gene delivery
    • R.D. Dayton, D.B. Wang, and R.L. Klein The advent of AAV9 expands applications for brain and spinal cord gene delivery Expert Opin. Biol. Ther. 12 2012 757 766
    • (2012) Expert Opin. Biol. Ther. , vol.12 , pp. 757-766
    • Dayton, R.D.1    Wang, D.B.2    Klein, R.L.3
  • 12
    • 0345736922 scopus 로고    scopus 로고
    • Nestin expression in pancreatic exocrine cell lineages
    • A. Delacour, V. Nepote, A. Trumpp, and P.L. Herrera Nestin expression in pancreatic exocrine cell lineages Mech. Dev. 121 2004 3 14
    • (2004) Mech. Dev. , vol.121 , pp. 3-14
    • Delacour, A.1    Nepote, V.2    Trumpp, A.3    Herrera, P.L.4
  • 13
    • 77954593040 scopus 로고    scopus 로고
    • A chemical-genetic approach for precise spatio-temporal control of cellular signaling
    • S. Dong, J.A. Allen, M. Farrell, and B.L. Roth A chemical-genetic approach for precise spatio-temporal control of cellular signaling Mol. Biosyst. 6 2010 1376 1380
    • (2010) Mol. Biosyst. , vol.6 , pp. 1376-1380
    • Dong, S.1    Allen, J.A.2    Farrell, M.3    Roth, B.L.4
  • 14
    • 33748655865 scopus 로고    scopus 로고
    • Nestin-Cre transgenic mouse line Nes-Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite-derived tissues
    • N.C. Dubois, D. Hofmann, K. Kaloulis, J.M. Bishop, and A. Trumpp Nestin-Cre transgenic mouse line Nes-Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite-derived tissues Genesis 44 2006 355 360
    • (2006) Genesis , vol.44 , pp. 355-360
    • Dubois, N.C.1    Hofmann, D.2    Kaloulis, K.3    Bishop, J.M.4    Trumpp, A.5
  • 16
    • 77955405459 scopus 로고    scopus 로고
    • Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland
    • C. Galichet, R. Lovell-Badge, and K. Rizzoti Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland PLoS ONE 5 2010 e11443
    • (2010) PLoS ONE , vol.5 , pp. 11443
    • Galichet, C.1    Lovell-Badge, R.2    Rizzoti, K.3
  • 17
    • 0034114786 scopus 로고    scopus 로고
    • Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter
    • M. Gannon, P.L. Herrera, and C.V. Wright Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter Genesis 26 2000 143 144
    • (2000) Genesis , vol.26 , pp. 143-144
    • Gannon, M.1    Herrera, P.L.2    Wright, C.V.3
  • 18
    • 1842584949 scopus 로고    scopus 로고
    • Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
    • Q. Gao, M.J. Wolfgang, S. Neschen, K. Morino, T.L. Horvath, G.I. Shulman, and X.Y. Fu Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation Proc. Natl. Acad. Sci. USA 101 2004 4661 4666
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4661-4666
    • Gao, Q.1    Wolfgang, M.J.2    Neschen, S.3    Morino, K.4    Horvath, T.L.5    Shulman, G.I.6    Fu, X.Y.7
  • 21
    • 84862225653 scopus 로고    scopus 로고
    • A pink mouse reports the switch from red to green fluorescence upon Cre-mediated recombination
    • H. Hartwich, S.V. Satheesh, and H.G. Nothwang A pink mouse reports the switch from red to green fluorescence upon Cre-mediated recombination BMC Res. Notes 5 2012 296
    • (2012) BMC Res. Notes , vol.5 , pp. 296
    • Hartwich, H.1    Satheesh, S.V.2    Nothwang, H.G.3
  • 22
    • 0027375278 scopus 로고
    • The 5′-flanking region of the rat synapsin i gene directs neuron-specific and developmentally regulated reporter gene expression in transgenic mice
    • C. Hoesche, A. Sauerwald, R.W. Veh, B. Krippl, and M.W. Kilimann The 5′-flanking region of the rat synapsin I gene directs neuron-specific and developmentally regulated reporter gene expression in transgenic mice J. Biol. Chem. 268 1993 26494 26502
    • (1993) J. Biol. Chem. , vol.268 , pp. 26494-26502
    • Hoesche, C.1    Sauerwald, A.2    Veh, R.W.3    Krippl, B.4    Kilimann, M.W.5
  • 23
    • 77957889131 scopus 로고    scopus 로고
    • Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line
    • G. Honig, A. Liou, M. Berger, M.S. German, and L.H. Tecott Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line J. Biomed. Sci. 17 2010 82
    • (2010) J. Biomed. Sci. , vol.17 , pp. 82
    • Honig, G.1    Liou, A.2    Berger, M.3    German, M.S.4    Tecott, L.H.5
  • 25
    • 84865191020 scopus 로고    scopus 로고
    • Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity
    • H.E. Kocalis, M.K. Turney, R.L. Printz, G.N. Laryea, L.J. Muglia, S.S. Davies, G.D. Stanwood, O.P. McGuinness, and K.D. Niswender Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity PLoS ONE 7 2012 e42981
    • (2012) PLoS ONE , vol.7 , pp. 42981
    • Kocalis, H.E.1    Turney, M.K.2    Printz, R.L.3    Laryea, G.N.4    Muglia, L.J.5    Davies, S.S.6    Stanwood, G.D.7    McGuinness, O.P.8    Niswender, K.D.9
  • 29
    • 84964900657 scopus 로고    scopus 로고
    • A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors
    • H. Liang, S. Hippenmeyer, and H.T. Ghashghaei A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors Biol. Open 1 2012 1200 1203
    • (2012) Biol. Open , vol.1 , pp. 1200-1203
    • Liang, H.1    Hippenmeyer, S.2    Ghashghaei, H.T.3
  • 32
    • 84879878335 scopus 로고    scopus 로고
    • Pancreas-Specific Cre Driver Lines and Considerations for Their Prudent Use
    • this issue
    • M.A. Magnuson, and A.B. Osipovich Pancreas-Specific Cre Driver Lines and Considerations for Their Prudent Use Cell Metab. 18 2013 9 20 this issue
    • (2013) Cell Metab. , vol.18 , pp. 9-20
    • Magnuson, M.A.1    Osipovich, A.B.2
  • 33
    • 76749118930 scopus 로고    scopus 로고
    • Ectopic recombination in the central and peripheral nervous system by aP2/FABP4-Cre mice: Implications for metabolism research
    • K. Martens, A. Bottelbergs, and M. Baes Ectopic recombination in the central and peripheral nervous system by aP2/FABP4-Cre mice: implications for metabolism research FEBS Lett. 584 2010 1054 1058
    • (2010) FEBS Lett. , vol.584 , pp. 1054-1058
    • Martens, K.1    Bottelbergs, A.2    Baes, M.3
  • 34
    • 34447293288 scopus 로고    scopus 로고
    • Genetically manipulated mice: A powerful tool with unsuspected caveats
    • K.I. Matthaei Genetically manipulated mice: a powerful tool with unsuspected caveats J. Physiol. 582 2007 481 488
    • (2007) J. Physiol. , vol.582 , pp. 481-488
    • Matthaei, K.I.1
  • 35
    • 78149447091 scopus 로고    scopus 로고
    • Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo
    • P.K. Mazur, B.M. Grüner, H. Nakhai, B. Sipos, U. Zimber-Strobl, L.J. Strobl, F. Radtke, R.M. Schmid, and J.T. Siveke Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo PLoS ONE 5 2010 e13578
    • (2010) PLoS ONE , vol.5 , pp. 13578
    • Mazur, P.K.1    Grüner, B.M.2    Nakhai, H.3    Sipos, B.4    Zimber-Strobl, U.5    Strobl, L.J.6    Radtke, F.7    Schmid, R.M.8    Siveke, J.T.9
  • 36
    • 34249729339 scopus 로고    scopus 로고
    • Conditional gene targeting on the pure C57BL/6 genetic background
    • M. Mishina, and K. Sakimura Conditional gene targeting on the pure C57BL/6 genetic background Neurosci. Res. 58 2007 105 112
    • (2007) Neurosci. Res. , vol.58 , pp. 105-112
    • Mishina, M.1    Sakimura, K.2
  • 37
    • 84871750212 scopus 로고    scopus 로고
    • A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods
    • S.E. Mullican, T. Tomaru, C.A. Gaddis, L.C. Peed, A. Sundaram, and M.A. Lazar A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods Mol. Endocrinol. 27 2013 127 134
    • (2013) Mol. Endocrinol. , vol.27 , pp. 127-134
    • Mullican, S.E.1    Tomaru, T.2    Gaddis, C.A.3    Peed, L.C.4    Sundaram, A.5    Lazar, M.A.6
  • 38
    • 38549123928 scopus 로고    scopus 로고
    • Cre activity causes widespread apoptosis and lethal anemia during embryonic development
    • L.A. Naiche, and V.E. Papaioannou Cre activity causes widespread apoptosis and lethal anemia during embryonic development Genesis 45 2007 768 775
    • (2007) Genesis , vol.45 , pp. 768-775
    • Naiche, L.A.1    Papaioannou, V.E.2
  • 39
    • 77950547451 scopus 로고    scopus 로고
    • Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits
    • S.L. Padilla, J.S. Carmody, and L.M. Zeltser Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits Nat. Med. 16 2010 403 405
    • (2010) Nat. Med. , vol.16 , pp. 403-405
    • Padilla, S.L.1    Carmody, J.S.2    Zeltser, L.M.3
  • 40
    • 84857418715 scopus 로고    scopus 로고
    • Defining POMC neurons using transgenic reagents: Impact of transient Pomc expression in diverse immature neuronal populations
    • S.L. Padilla, D. Reef, and L.M. Zeltser Defining POMC neurons using transgenic reagents: impact of transient Pomc expression in diverse immature neuronal populations Endocrinology 153 2012 1219 1231
    • (2012) Endocrinology , vol.153 , pp. 1219-1231
    • Padilla, S.L.1    Reef, D.2    Zeltser, L.M.3
  • 41
    • 0035949704 scopus 로고    scopus 로고
    • Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo
    • A. Pfeifer, E.P. Brandon, N. Kootstra, F.H. Gage, and I.M. Verma Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo Proc. Natl. Acad. Sci. USA 98 2001 11450 11455
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11450-11455
    • Pfeifer, A.1    Brandon, E.P.2    Kootstra, N.3    Gage, F.H.4    Verma, I.M.5
  • 42
    • 84872615923 scopus 로고    scopus 로고
    • Conditional deletion of histone deacetylase-4 in the central nervous system has no major effect on brain architecture or neuronal viability
    • V. Price, L. Wang, and S.R. D'Mello Conditional deletion of histone deacetylase-4 in the central nervous system has no major effect on brain architecture or neuronal viability J. Neurosci. Res. 91 2013 407 415
    • (2013) J. Neurosci. Res. , vol.91 , pp. 407-415
    • Price, V.1    Wang, L.2    D'Mello, S.R.3
  • 43
    • 79955908536 scopus 로고    scopus 로고
    • A non-specific effect associated with conditional transgene expression based on Cre-loxP strategy in mice
    • L. Qiu, J.A. Rivera-Pérez, and Z. Xu A non-specific effect associated with conditional transgene expression based on Cre-loxP strategy in mice PLoS ONE 6 2011 e18778
    • (2011) PLoS ONE , vol.6 , pp. 18778
    • Qiu, L.1    Rivera-Pérez, J.A.2    Xu, Z.3
  • 46
    • 32344441180 scopus 로고    scopus 로고
    • Synapsin i Cre transgene expression in male mice produces germline recombination in progeny
    • D. Rempe, G. Vangeison, J. Hamilton, Y. Li, M. Jepson, and H.J. Federoff Synapsin I Cre transgene expression in male mice produces germline recombination in progeny Genesis 44 2006 44 49
    • (2006) Genesis , vol.44 , pp. 44-49
    • Rempe, D.1    Vangeison, G.2    Hamilton, J.3    Li, Y.4    Jepson, M.5    Federoff, H.J.6
  • 49
    • 2942615168 scopus 로고    scopus 로고
    • Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types
    • S.E. Schonhoff, M. Giel-Moloney, and A.B. Leiter Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types Dev. Biol. 270 2004 443 454
    • (2004) Dev. Biol. , vol.270 , pp. 443-454
    • Schonhoff, S.E.1    Giel-Moloney, M.2    Leiter, A.B.3
  • 50
    • 0036291255 scopus 로고    scopus 로고
    • Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract
    • X. Shao, S. Somlo, and P. Igarashi Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract J. Am. Soc. Nephrol. 13 2002 1837 1846
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 1837-1846
    • Shao, X.1    Somlo, S.2    Igarashi, P.3
  • 51
    • 78049445907 scopus 로고    scopus 로고
    • Brain expression of Cre recombinase driven by pancreas-specific promoters
    • J. Song, Y. Xu, X. Hu, B. Choi, and Q. Tong Brain expression of Cre recombinase driven by pancreas-specific promoters Genesis 48 2010 628 634
    • (2010) Genesis , vol.48 , pp. 628-634
    • Song, J.1    Xu, Y.2    Hu, X.3    Choi, B.4    Tong, Q.5
  • 52
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • P. Soriano Generalized lacZ expression with the ROSA26 Cre reporter strain Nat. Genet. 21 1999 70 71
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 53
    • 0019888362 scopus 로고
    • Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites
    • N. Sternberg, and D. Hamilton Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites J. Mol. Biol. 150 1981 467 486
    • (1981) J. Mol. Biol. , vol.150 , pp. 467-486
    • Sternberg, N.1    Hamilton, D.2
  • 55
    • 0035430280 scopus 로고    scopus 로고
    • Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes
    • A. Takano, T. Haruta, M. Iwata, I. Usui, T. Uno, J. Kawahara, E. Ueno, T. Sasaoka, and M. Kobayashi Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes Diabetes 50 2001 1891 1900
    • (2001) Diabetes , vol.50 , pp. 1891-1900
    • Takano, A.1    Haruta, T.2    Iwata, M.3    Usui, I.4    Uno, T.5    Kawahara, J.6    Ueno, E.7    Sasaoka, T.8    Kobayashi, M.9
  • 56
    • 0024494423 scopus 로고
    • Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells
    • S. Thompson, A.R. Clarke, A.M. Pow, M.L. Hooper, and D.W. Melton Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells Cell 56 1989 313 321
    • (1989) Cell , vol.56 , pp. 313-321
    • Thompson, S.1    Clarke, A.R.2    Pow, A.M.3    Hooper, M.L.4    Melton, D.W.5
  • 57
    • 0343415768 scopus 로고    scopus 로고
    • Mammalian genomes contain active recombinase recognition sites
    • B. Thyagarajan, M.J. Guimarães, A.C. Groth, and M.P. Calos Mammalian genomes contain active recombinase recognition sites Gene 244 2000 47 54
    • (2000) Gene , vol.244 , pp. 47-54
    • Thyagarajan, B.1    Guimarães, M.J.2    Groth, A.C.3    Calos, M.P.4
  • 59
    • 0020036242 scopus 로고
    • Deficiency of corpus callosum varies with strain and supplier of the mice
    • D. Wahlsten Deficiency of corpus callosum varies with strain and supplier of the mice Brain Res. 239 1982 329 347
    • (1982) Brain Res. , vol.239 , pp. 329-347
    • Wahlsten, D.1
  • 60
    • 37349055356 scopus 로고    scopus 로고
    • Fate mapping Nkx2.1-lineage cells in the mouse telencephalon
    • Q. Xu, M. Tam, and S.A. Anderson Fate mapping Nkx2.1-lineage cells in the mouse telencephalon J. Comp. Neurol. 506 2008 16 29
    • (2008) J. Comp. Neurol. , vol.506 , pp. 16-29
    • Xu, Q.1    Tam, M.2    Anderson, S.A.3
  • 61
    • 75949085585 scopus 로고    scopus 로고
    • Sonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates
    • Q. Xu, L. Guo, H. Moore, R.R. Waclaw, K. Campbell, and S.A. Anderson Sonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates Neuron 65 2010 328 340
    • (2010) Neuron , vol.65 , pp. 328-340
    • Xu, Q.1    Guo, L.2    Moore, H.3    Waclaw, R.R.4    Campbell, K.5    Anderson, S.A.6
  • 63
    • 84863012490 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality
    • J. Zhang, Y. Wang, Z. Gao, Z. Yun, and J. Ye Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality Clin. Exp. Pharmacol. Physiol. 39 2012 145 150
    • (2012) Clin. Exp. Pharmacol. Physiol. , vol.39 , pp. 145-150
    • Zhang, J.1    Wang, Y.2    Gao, Z.3    Yun, Z.4    Ye, J.5


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