Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner

Cell Metabolism

Volumn 13, Issue 5, 2011, Pages 562-572

  Rousso Noori, Liat ^a   Knobler, Hilla ^b   Levy Apter, Einat ^a   Kuperman, Yael ^a   Neufeld Cohen, Adi ^a   Keshet, Yonat ^a   Akepati, Vasudheva R ^a   Klinghoffer, Richard A ^c,d   Chen, Alon ^a   Elson, Ari ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b KAPLAN MEDICAL CENTER   (Israel)

^c CEPTYR Inc   (United States)

^d Presage Biosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; PROTEIN TYROSINE PHOSPHATASE EPSILON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOWN REGULATION; ENERGY EXPENDITURE; FEMALE; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HYPERSENSITIVITY; IN VIVO STUDY; LIPID DIET; MALE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OBESITY; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WEIGHT GAIN;

ANIMALS; BODY WEIGHT; CELLS, CULTURED; DIET, ATHEROGENIC; DOWN-REGULATION; FEMALE; GLUCOSE; HOMEOSTASIS; HUMANS; HYPOTHALAMUS; IMMUNOBLOTTING; JANUS KINASE 2; LEPTIN; MICE; MICE, KNOCKOUT; OBESITY; PHOSPHORYLATION; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 4; RECEPTORS, LEPTIN; SIGNAL TRANSDUCTION;

MUS;

EID: 79955599937     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2011.02.017     Document Type: Article

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