-
1
-
-
84884182859
-
FA1 induces pro-inflammatory and anti-adipogenic pathways/markers in human myotubes established from lean, obese, and type 2 diabetic subjects but not insulin resistance.
-
doi: 10.3389/fendo.2013.00045.
-
Abdallah, B. M., Beck-Nielsen, H., and Gaster, M. (2013). FA1 induces pro-inflammatory and anti-adipogenic pathways/markers in human myotubes established from lean, obese, and type 2 diabetic subjects but not insulin resistance. Front. Endocrinol. (Lausanne) 4:45. doi: 10.3389/fendo.2013.00045
-
(2013)
Front. Endocrinol. (Lausanne)
, vol.4
, pp. 45
-
-
Abdallah, B.M.1
Beck-Nielsen, H.2
Gaster, M.3
-
2
-
-
0028292032
-
Isodisomy of chromosome 6 in a newborn with methylmalonic acidemia and agenesis of pancreatic beta cells causing diabetes mellitus
-
doi: 10.1172/JCI117339
-
Abramowicz, M. J., Andrien, M., Dupont, E., Dorchy, H., Parma, J., Duprez, L., et al. (1994). Isodisomy of chromosome 6 in a newborn with methylmalonic acidemia and agenesis of pancreatic beta cells causing diabetes mellitus. J. Clin. Invest. 94, 418-421. doi: 10.1172/JCI117339
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 418-421
-
-
Abramowicz, M.J.1
Andrien, M.2
Dupont, E.3
Dorchy, H.4
Parma, J.5
Duprez, L.6
-
3
-
-
84873524564
-
Conditional deletions refine the embryonic requirement for Dlk1
-
doi: 10.1016/j.mod.2012.09.010
-
Appelbe, O. K., Yevtodiyenko, A., Muniz-Talavera, H., and Schmidt, J. V. (2013). Conditional deletions refine the embryonic requirement for Dlk1. Mech. Dev. 130, 143-159. doi: 10.1016/j.mod.2012.09.010
-
(2013)
Mech. Dev.
, vol.130
, pp. 143-159
-
-
Appelbe, O.K.1
Yevtodiyenko, A.2
Muniz-Talavera, H.3
Schmidt, J.V.4
-
4
-
-
0034253796
-
A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC
-
doi: 10.1006/geno.2000.6266
-
Arima, T., Drewell, R. A., Oshimura, M., Wake, N., and Surani, M. A. (2000). A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC. Genomics 67, 248-255. doi: 10.1006/geno.2000.6266
-
(2000)
Genomics
, vol.67
, pp. 248-255
-
-
Arima, T.1
Drewell, R.A.2
Oshimura, M.3
Wake, N.4
Surani, M.A.5
-
5
-
-
18744406710
-
ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome
-
doi: 10.1093/nar/gki555
-
Arima, T., Kamikihara, T., Hayashida, T., Kato, K., Inoue, T., Shirayoshi, Y., et al. (2005). ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome. Nucleic Acids Res. 33, 2650-2660. doi: 10.1093/nar/gki555
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 2650-2660
-
-
Arima, T.1
Kamikihara, T.2
Hayashida, T.3
Kato, K.4
Inoue, T.5
Shirayoshi, Y.6
-
6
-
-
84975856269
-
Economic costs of diabetes in the U.S. in 2012
-
doi: 10.2337/dc12-2625
-
Association, A. D. (2013). Economic costs of diabetes in the U.S. in 2012. Diabetes Care 36, 1033-1046. doi: 10.2337/dc12-2625
-
(2013)
Diabetes Care
, vol.36
, pp. 1033-1046
-
-
Association, A.D.1
-
7
-
-
84893870589
-
Targeting the cell cycle inhibitor p57Kip2 promotes adult human Β cell replication
-
doi: 10.1172/JCI69519
-
Avrahami, D., Li, C., Yu, M., Jiao, Y., Zhang, J., Naji, A., et al. (2014). Targeting the cell cycle inhibitor p57Kip2 promotes adult human Β cell replication. J. Clin. Invest. 124, 670-674. doi: 10.1172/JCI69519
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 670-674
-
-
Avrahami, D.1
Li, C.2
Yu, M.3
Jiao, Y.4
Zhang, J.5
Naji, A.6
-
8
-
-
80755187797
-
Genomic imprinting: a mammalian epigenetic discovery model
-
doi: 10.1146/annurev-genet-110410-132459
-
Barlow, D. P. (2011). Genomic imprinting: a mammalian epigenetic discovery model. Annu. Rev. Genet. 45, 379-403. doi: 10.1146/annurev-genet-110410-132459
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 379-403
-
-
Barlow, D.P.1
-
9
-
-
67349199566
-
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
-
doi: 10.1038/ng.381
-
Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., et al. (2009). Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat. Genet. 41, 703-707. doi: 10.1038/ng.381
-
(2009)
Nat. Genet.
, vol.41
, pp. 703-707
-
-
Barrett, J.C.1
Clayton, D.G.2
Concannon, P.3
Akolkar, B.4
Cooper, J.D.5
Erlich, H.A.6
-
10
-
-
80455173456
-
Mammalian genomic imprinting. Cold Spring Harb.
-
doi: 10.1101/cshperspect.a002592.
-
Bartolomei, M. S., and Ferguson-Smith, A. C. (2011). Mammalian genomic imprinting. Cold Spring Harb. Perspect. Biol. 3:a002592. doi: 10.1101/cshperspect.a002592
-
(2011)
Perspect. Biol.
, vol.3
-
-
Bartolomei, M.S.1
Ferguson-Smith, A.C.2
-
11
-
-
0025809321
-
Parental imprinting of the mouse H19 gene
-
doi: 10.1038/351153a0
-
Bartolomei, M. S., Zemel, S., and Tilghman, S. M. (1991). Parental imprinting of the mouse H19 gene. Nature 351, 153-155. doi: 10.1038/351153a0
-
(1991)
Nature
, vol.351
, pp. 153-155
-
-
Bartolomei, M.S.1
Zemel, S.2
Tilghman, S.M.3
-
12
-
-
84875200257
-
Long noncoding RNAs: cellular address codes in development and disease
-
doi: 10.1016/j.cell.2013.02.012
-
Batista, P. J., and Chang, H. Y. (2013). Long noncoding RNAs: cellular address codes in development and disease. Cell 152, 1298-1307. doi: 10.1016/j.cell.2013.02.012
-
(2013)
Cell
, vol.152
, pp. 1298-1307
-
-
Batista, P.J.1
Chang, H.Y.2
-
13
-
-
0034713375
-
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
-
doi: 10.1038/35013100
-
Bell, A. C., and Felsenfeld, G. (2000). Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 405, 482-485. doi: 10.1038/35013100
-
(2000)
Nature
, vol.405
, pp. 482-485
-
-
Bell, A.C.1
Felsenfeld, G.2
-
14
-
-
49649119726
-
Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene in multiple myeloma
-
doi: 10.3816/CLM.2008.n.021
-
Benetatos, L., Dasoula, A., Hatzimichael, E., Georgiou, I., Syrrou, M., and Bourantas, K. L. (2008). Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene in multiple myeloma. Clin. Lymphoma Myeloma 8, 171-175. doi: 10.3816/CLM.2008.n.021
-
(2008)
Clin. Lymphoma Myeloma
, vol.8
, pp. 171-175
-
-
Benetatos, L.1
Dasoula, A.2
Hatzimichael, E.3
Georgiou, I.4
Syrrou, M.5
Bourantas, K.L.6
-
15
-
-
79959695174
-
MEG3 imprinted gene contribution in tumorigenesis
-
doi: 10.1002/ijc.26052
-
Benetatos, L., Vartholomatos, G., and Hatzimichael, E. (2011). MEG3 imprinted gene contribution in tumorigenesis. Int. J. Cancer 129, 773-779. doi: 10.1002/ijc.26052
-
(2011)
Int. J. Cancer
, vol.129
, pp. 773-779
-
-
Benetatos, L.1
Vartholomatos, G.2
Hatzimichael, E.3
-
16
-
-
23044437498
-
RNA meets chromatin
-
doi: 10.1101/gad.1324305
-
Bernstein, E., and Allis, C. D. (2005). RNA meets chromatin. Genes Dev. 19, 1635-1655. doi: 10.1101/gad.1324305
-
(2005)
Genes Dev.
, vol.19
, pp. 1635-1655
-
-
Bernstein, E.1
Allis, C.D.2
-
17
-
-
84874626174
-
Epigenomic plasticity enables human pancreatic a to Β cell reprogramming
-
doi: 10.1172/JCI66514
-
Bramswig, N. C., Everett, L. J., Schug, J., Dorrell, C., Liu, C., Luo, Y., et al. (2013). Epigenomic plasticity enables human pancreatic a to Β cell reprogramming. J. Clin. Invest. 123, 1275-1284. doi: 10.1172/JCI66514
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1275-1284
-
-
Bramswig, N.C.1
Everett, L.J.2
Schug, J.3
Dorrell, C.4
Liu, C.5
Luo, Y.6
-
18
-
-
84861683155
-
Epigenetics and diabetes treatment: an unrealized promise? Trends Endocrinol
-
doi: 10.1016/j.tem.2012.02.002
-
Bramswig, N. C., and Kaestner, K. H. (2012). Epigenetics and diabetes treatment: an unrealized promise? Trends Endocrinol. Metab. 23, 286-291. doi: 10.1016/j.tem.2012.02.002
-
(2012)
Metab.
, vol.23
, pp. 286-291
-
-
Bramswig, N.C.1
Kaestner, K.H.2
-
19
-
-
0025012640
-
The product of the H19 gene may function as an RNA
-
Brannan, C. I., Dees, E. C., Ingram, R. S., and Tilghman, S. M. (1990). The product of the H19 gene may function as an RNA. Mol. Cell. Biol. 10, 28-36.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 28-36
-
-
Brannan, C.I.1
Dees, E.C.2
Ingram, R.S.3
Tilghman, S.M.4
-
20
-
-
0025961771
-
A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
-
doi: 10.1038/349038a0
-
Brown, C. J., Ballabio, A., Rupert, J. L., Lafreniere, R. G., Grompe, M., Tonlorenzi, R., et al. (1991). A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 349, 38-44. doi: 10.1038/349038a0
-
(1991)
Nature
, vol.349
, pp. 38-44
-
-
Brown, C.J.1
Ballabio, A.2
Rupert, J.L.3
Lafreniere, R.G.4
Grompe, M.5
Tonlorenzi, R.6
-
21
-
-
80052978224
-
Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
-
doi: 10.1101/gad.17446611
-
Cabili, M. N., Trapnell, C., Goff, L., Koziol, M., Tazon-Vega, B., Regev, A., et al. (2011). Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 25, 1915-1927. doi: 10.1101/gad.17446611
-
(2011)
Genes Dev.
, vol.25
, pp. 1915-1927
-
-
Cabili, M.N.1
Trapnell, C.2
Goff, L.3
Koziol, M.4
Tazon-Vega, B.5
Regev, A.6
-
22
-
-
0030744676
-
Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas
-
doi: 10.1210/endo.138.9.5408
-
Carlsson, C., Tornehave, D., Lindberg, K., Galante, P., Billestrup, N., Michelsen, B., et al. (1997). Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas. Endocrinology 138, 3940-3948. doi: 10.1210/endo.138.9.5408
-
(1997)
Endocrinology
, vol.138
, pp. 3940-3948
-
-
Carlsson, C.1
Tornehave, D.2
Lindberg, K.3
Galante, P.4
Billestrup, N.5
Michelsen, B.6
-
23
-
-
24644519490
-
The transcriptional landscape of the mammalian genome
-
doi: 10.1126/science.1112014
-
Carninci, P., Kasukawa, T., Katayama, S., Gough, J., Frith, M. C., Maeda, N., et al. (2005). The transcriptional landscape of the mammalian genome. Science 309, 1559-1563. doi: 10.1126/science.1112014
-
(2005)
Science
, vol.309
, pp. 1559-1563
-
-
Carninci, P.1
Kasukawa, T.2
Katayama, S.3
Gough, J.4
Frith, M.C.5
Maeda, N.6
-
24
-
-
84897128298
-
The noncoding RNA revolution-trashing old rules to forge new ones
-
doi: 10.1016/j.cell.2014.03.008
-
Cech, T. R., and Steitz, J. A. (2014). The noncoding RNA revolution-trashing old rules to forge new ones. Cell 157, 77-94. doi: 10.1016/j.cell.2014.03.008
-
(2014)
Cell
, vol.157
, pp. 77-94
-
-
Cech, T.R.1
Steitz, J.A.2
-
25
-
-
84655162045
-
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
-
doi: 10.1038/ng.1019
-
Cho, Y. S., Chen, C.-H., Hu, C., Long, J., Ong, R. T. H., Sim, X., et al. (2012). Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat. Genet. 44, 67-72. doi: 10.1038/ng.1019
-
(2012)
Nat. Genet.
, vol.44
, pp. 67-72
-
-
Cho, Y.S.1
Chen, C.-H.2
Hu, C.3
Long, J.4
Ong, R.T.H.5
Sim, X.6
-
26
-
-
0033055126
-
Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac
-
doi: 10.1016/S0169-328X(99)00116-3
-
Ciani, E., Hoffmann, A., Schmidt, P., Journot, L., and Spengler, D. (1999). Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac. Brain Res. Mol. Brain Res. 69, 290-294. doi: 10.1016/S0169-328X(99)00116-3
-
(1999)
Brain Res. Mol. Brain Res.
, vol.69
, pp. 290-294
-
-
Ciani, E.1
Hoffmann, A.2
Schmidt, P.3
Journot, L.4
Spengler, D.5
-
27
-
-
0030760633
-
Inactivation of H19, an imprinted and putative tumor repressor gene, is a preneoplastic event during Wilms' tumorigenesis
-
Cui, H., Hedborg, F., He, L., Nordenskjöld, A., Sandstedt, B., Pfeifer-Ohlsson, S., et al. (1997). Inactivation of H19, an imprinted and putative tumor repressor gene, is a preneoplastic event during Wilms' tumorigenesis. Cancer Res. 57, 4469-4473.
-
(1997)
Cancer Res.
, vol.57
, pp. 4469-4473
-
-
Cui, H.1
Hedborg, F.2
He, L.3
Nordenskjöld, A.4
Sandstedt, B.5
Pfeifer-Ohlsson, S.6
-
28
-
-
44149101388
-
Genomic imprinting at the mammalian Dlk1-Dio3 domain
-
doi: 10.1016/j.tig.2008.03.011
-
da Rocha, S. T., Edwards, C. A., Ito, M., Ogata, T., and Ferguson-Smith, A. C. (2008). Genomic imprinting at the mammalian Dlk1-Dio3 domain. Trends Genet. 24, 306-316. doi: 10.1016/j.tig.2008.03.011
-
(2008)
Trends Genet.
, vol.24
, pp. 306-316
-
-
da Rocha, S.T.1
Edwards, C.A.2
Ito, M.3
Ogata, T.4
Ferguson-Smith, A.C.5
-
29
-
-
84897452599
-
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
-
doi: 10.1371/journal.pgen.1004160.
-
Dayeh, T., Volkov, P., Salö, S., Hall, E., Nilsson, E., Olsson, A. H., et al. (2014). Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion. PLoS Genet. 10:e1004160. doi: 10.1371/journal.pgen.1004160
-
(2014)
PLoS Genet.
, vol.10
-
-
Dayeh, T.1
Volkov, P.2
Salö, S.3
Hall, E.4
Nilsson, E.5
Olsson, A.H.6
-
30
-
-
0025320906
-
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
-
doi: 10.1038/345078a0
-
DeChiara, T. M., Efstratiadis, A., and Robertson, E. J. (1990). A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345, 78-80. doi: 10.1038/345078a0
-
(1990)
Nature
, vol.345
, pp. 78-80
-
-
DeChiara, T.M.1
Efstratiadis, A.2
Robertson, E.J.3
-
31
-
-
0030880778
-
Somatic deletion of the imprinted 11p15 region in sporadic persistent hyperinsulinemic hypoglycemia of infancy is specific of focal adenomatous hyperplasia and endorses partial pancreatectomy
-
doi: 10.1172/JCI119594
-
de Lonlay, P., Fournet, J. C., Rahier, J., Gross-Morand, M. S., Poggi-Travert, F., Foussier, V., et al. (1997). Somatic deletion of the imprinted 11p15 region in sporadic persistent hyperinsulinemic hypoglycemia of infancy is specific of focal adenomatous hyperplasia and endorses partial pancreatectomy. J. Clin. Invest. 100, 802-807. doi: 10.1172/JCI119594
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 802-807
-
-
de Lonlay, P.1
Fournet, J.C.2
Rahier, J.3
Gross-Morand, M.S.4
Poggi-Travert, F.5
Foussier, V.6
-
32
-
-
84865727393
-
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
-
doi: 10.1101/gr.132159.111
-
Derrien, T., Johnson, R., Bussotti, G., Tanzer, A., Djebali, S., Tilgner, H., et al. (2012). The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 22, 1775-1789. doi: 10.1101/gr.132159.111
-
(2012)
Genome Res.
, vol.22
, pp. 1775-1789
-
-
Derrien, T.1
Johnson, R.2
Bussotti, G.3
Tanzer, A.4
Djebali, S.5
Tilgner, H.6
-
33
-
-
0034063375
-
Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes
-
doi: 10.1172/JCI5656
-
Devedjian, J. C., George, M., Casellas, A., Pujol, A., Visa, J., Pelegrín, M., et al. (2000). Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes. J. Clin. Invest. 105, 731-740. doi: 10.1172/JCI5656
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 731-740
-
-
Devedjian, J.C.1
George, M.2
Casellas, A.3
Pujol, A.4
Visa, J.5
Pelegrín, M.6
-
34
-
-
84860599353
-
Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia
-
doi: 10.2337/db11-1314
-
Ding, G.-L., Wang, F.-F., Shu, J., Tian, S., Jiang, Y., Zhang, D., et al. (2012). Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia. Diabetes 61, 1133-1142. doi: 10.2337/db11-1314
-
(2012)
Diabetes
, vol.61
, pp. 1133-1142
-
-
Ding, G.-L.1
Wang, F.-F.2
Shu, J.3
Tian, S.4
Jiang, Y.5
Zhang, D.6
-
35
-
-
84865757142
-
Landscape of transcription in human cells
-
doi: 10.1038/nature11233
-
Djebali, S., Davis, C. A., Merkel, A., Dobin, A., Lassmann, T., Mortazavi, A., et al. (2012). Landscape of transcription in human cells. Nature 489, 101-108. doi: 10.1038/nature11233
-
(2012)
Nature
, vol.489
, pp. 101-108
-
-
Djebali, S.1
Davis, C.A.2
Merkel, A.3
Dobin, A.4
Lassmann, T.5
Mortazavi, A.6
-
36
-
-
80054682732
-
Transcriptomes of the major human pancreatic cell types
-
doi: 10.1007/s00125-011-2283-5
-
Dorrell, C., Schug, J., Lin, C. F., Canaday, P. S., Fox, A. J., Smirnova, O., et al. (2011). Transcriptomes of the major human pancreatic cell types. Diabetologia 54, 2832-2844. doi: 10.1007/s00125-011-2283-5
-
(2011)
Diabetologia
, vol.54
, pp. 2832-2844
-
-
Dorrell, C.1
Schug, J.2
Lin, C.F.3
Canaday, P.S.4
Fox, A.J.5
Smirnova, O.6
-
37
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
doi: 10.1038/ng.520
-
Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., et al. (2010). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat. Genet. 42, 105-116. doi: 10.1038/ng.520
-
(2010)
Nat. Genet.
, vol.42
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
Saxena, R.4
Soranzo, N.5
Jackson, A.U.6
-
38
-
-
79954493958
-
Differential expression pattern of ZAC in developing mouse and human pancreas
-
doi: 10.1007/s10735-011-9315-9
-
Du, X., Rousseau, M., Ounissi-Benkalha, H., Marchand, L., Jetha, A., Paraskevas, S., et al. (2011). Differential expression pattern of ZAC in developing mouse and human pancreas. J. Mol. Histol. 42, 129-136. doi: 10.1007/s10735-011-9315-9
-
(2011)
J. Mol. Histol.
, vol.42
, pp. 129-136
-
-
Du, X.1
Rousseau, M.2
Ounissi-Benkalha, H.3
Marchand, L.4
Jetha, A.5
Paraskevas, S.6
-
39
-
-
84864047695
-
Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development
-
doi: 10.4161/rna.21089
-
Eißmann, M., Gutschner, T., Hämmerle, M., Günther, S., Caudron-Herger, M., Groβ, M., et al. (2012). Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development. RNA Biol. 9, 1076-1087. doi: 10.4161/rna.21089
-
(2012)
RNA Biol.
, vol.9
, pp. 1076-1087
-
-
Eißmann, M.1
Gutschner, T.2
Hämmerle, M.3
Günther, S.4
Caudron-Herger, M.5
Groß, M.6
-
40
-
-
3543010196
-
Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations
-
doi: 10.1038/ng1399
-
Engel, N., West, A. G., Felsenfeld, G., and Bartolomei, M. S. (2004). Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations. Nat. Genet. 36, 883-888. doi: 10.1038/ng1399
-
(2004)
Nat. Genet.
, vol.36
, pp. 883-888
-
-
Engel, N.1
West, A.G.2
Felsenfeld, G.3
Bartolomei, M.S.4
-
41
-
-
0035960122
-
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
-
doi: 10.1056/NEJMra002168
-
Fajans, S. S., Bell, G. I., and Polonsky, K. S. (2001). Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N. Engl. J. Med. 345, 971-980. doi: 10.1056/NEJMra002168
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
42
-
-
84859098510
-
Possible roles of DLK1 in the Notch pathway during development and disease
-
doi: 10.1016/j.bbadis.2012.02.003
-
Falix, F. A., Aronson, D. C., Lamers, W. H., and Gaemers, I. C. (2012). Possible roles of DLK1 in the Notch pathway during development and disease. Biochim. Biophys. Acta 1822, 988-995. doi: 10.1016/j.bbadis.2012.02.003
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 988-995
-
-
Falix, F.A.1
Aronson, D.C.2
Lamers, W.H.3
Gaemers, I.C.4
-
43
-
-
84890559595
-
Long non-coding RNAs: new players in cell differentiation and development
-
doi: 10.1038/nrg3606
-
Fatica, A., and Bozzoni, I. (2014). Long non-coding RNAs: new players in cell differentiation and development. Nat. Rev. Genet. 15, 7-21. doi: 10.1038/nrg3606
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 7-21
-
-
Fatica, A.1
Bozzoni, I.2
-
44
-
-
0036831864
-
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1
-
doi: 10.1038/ng988
-
Fitzpatrick, G. V., Soloway, P. D., and Higgins, M. J. (2002). Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat. Genet. 32, 426-431. doi: 10.1038/ng988
-
(2002)
Nat. Genet.
, vol.32
, pp. 426-431
-
-
Fitzpatrick, G.V.1
Soloway, P.D.2
Higgins, M.J.3
-
45
-
-
0034970925
-
Unbalanced expression of 11p15 imprinted genes in focal forms of congenital hyperinsulinism: association with a reduction to homozygosity of a mutation in ABCC8 or KCNJ11
-
doi: 10.1016/S0002-9440(10)64689-5
-
Fournet, J. C., Mayaud, C., de Lonlay, P., Gross-Morand, M. S., Verkarre, V., Castanet, M., et al. (2001). Unbalanced expression of 11p15 imprinted genes in focal forms of congenital hyperinsulinism: association with a reduction to homozygosity of a mutation in ABCC8 or KCNJ11. Am. J. Pathol. 158, 2177-2184. doi: 10.1016/S0002-9440(10)64689-5
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 2177-2184
-
-
Fournet, J.C.1
Mayaud, C.2
de Lonlay, P.3
Gross-Morand, M.S.4
Verkarre, V.5
Castanet, M.6
-
46
-
-
0037291014
-
Expression, biosynthesis and release of preadipocyte factor-1/delta-like protein/fetal antigen-1 in pancreatic beta-cells: possible physiological implications
-
doi: 10.1677/joe.0.1760257
-
Friedrichsen, B. N., Carlsson, C., Møldrup, A., Michelsen, B., Jensen, C. H., Teisner, B., et al. (2003). Expression, biosynthesis and release of preadipocyte factor-1/delta-like protein/fetal antigen-1 in pancreatic beta-cells: possible physiological implications. J. Endocrinol. 176, 257-266. doi: 10.1677/joe.0.1760257
-
(2003)
J. Endocrinol.
, vol.176
, pp. 257-266
-
-
Friedrichsen, B.N.1
Carlsson, C.2
Møldrup, A.3
Michelsen, B.4
Jensen, C.H.5
Teisner, B.6
-
47
-
-
0034163575
-
An imprinted locus associated with transient neonatal diabetes mellitus
-
doi: 10.1093/hmg/9.4.589
-
Gardner, R. J., Mackay, D. J., Mungall, A. J., Polychronakos, C., Siebert, R., Shield, J. P., et al. (2000). An imprinted locus associated with transient neonatal diabetes mellitus. Hum. Mol. Genet. 9, 589-596. doi: 10.1093/hmg/9.4.589
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 589-596
-
-
Gardner, R.J.1
Mackay, D.J.2
Mungall, A.J.3
Polychronakos, C.4
Siebert, R.5
Shield, J.P.6
-
48
-
-
77649086970
-
A map of open chromatin in human pancreatic islets
-
doi: 10.1038/ng.530
-
Gaulton, K. J., Nammo, T., Pasquali, L., Simon, J. M., Giresi, P. G., Fogarty, M. P., et al. (2010). A map of open chromatin in human pancreatic islets. Nat. Genet. 42, 255-259. doi: 10.1038/ng.530
-
(2010)
Nat. Genet.
, vol.42
, pp. 255-259
-
-
Gaulton, K.J.1
Nammo, T.2
Pasquali, L.3
Simon, J.M.4
Giresi, P.G.5
Fogarty, M.P.6
-
49
-
-
25144454048
-
Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome
-
doi: 10.1038/ng1629
-
Gicquel, C., Rossignol, S., Cabrol, S., Houang, M., Steunou, V., Barbu, V., et al. (2005). Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome. Nat. Genet. 37, 1003-1007. doi: 10.1038/ng1629
-
(2005)
Nat. Genet.
, vol.37
, pp. 1003-1007
-
-
Gicquel, C.1
Rossignol, S.2
Cabrol, S.3
Houang, M.4
Steunou, V.5
Barbu, V.6
-
50
-
-
84873829893
-
The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
-
doi: 10.1016/j.devcel.2012.12.012
-
Grote, P., Wittler, L., Hendrix, D., Koch, F., Währisch, S., Beisaw, A., et al. (2013). The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse. Dev. Cell 24, 206-214. doi: 10.1016/j.devcel.2012.12.012
-
(2013)
Dev. Cell
, vol.24
, pp. 206-214
-
-
Grote, P.1
Wittler, L.2
Hendrix, D.3
Koch, F.4
Währisch, S.5
Beisaw, A.6
-
51
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
doi: 10.1038/nature08975
-
Gupta, R. A., Shah, N., Wang, K. C., Kim, J., Horlings, H. M., Wong, D. J., et al. (2010). Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 464, 1071-1076. doi: 10.1038/nature08975
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
Shah, N.2
Wang, K.C.3
Kim, J.4
Horlings, H.M.5
Wong, D.J.6
-
52
-
-
84879837310
-
MALAT1 - a paradigm for long noncoding RNA function in cancer
-
doi: 10.1007/s00109-013-1028-y
-
Gutschner, T., Hämmerle, M., and Diederichs, S. (2013). MALAT1 - a paradigm for long noncoding RNA function in cancer. J. Mol. Med. 91, 791-801. doi: 10.1007/s00109-013-1028-y
-
(2013)
J. Mol. Med.
, vol.91
, pp. 791-801
-
-
Gutschner, T.1
Hämmerle, M.2
Diederichs, S.3
-
53
-
-
62249133709
-
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
-
doi: 10.1038/nature07672
-
Guttman, M., Amit, I., Garber, M., French, C., Lin, M. F., Feldser, D., et al. (2009). Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 458, 223-227. doi: 10.1038/nature07672
-
(2009)
Nature
, vol.458
, pp. 223-227
-
-
Guttman, M.1
Amit, I.2
Garber, M.3
French, C.4
Lin, M.F.5
Feldser, D.6
-
54
-
-
80052869283
-
lincRNAs act in the circuitry controlling pluripotency and differentiation
-
doi: 10.1038/nature10398
-
Guttman, M., Donaghey, J., Carey, B. W., Garber, M., Grenier, J. K., Munson, G., et al. (2011). lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature 477, 295-300. doi: 10.1038/nature10398
-
(2011)
Nature
, vol.477
, pp. 295-300
-
-
Guttman, M.1
Donaghey, J.2
Carey, B.W.3
Garber, M.4
Grenier, J.K.5
Munson, G.6
-
55
-
-
84857066786
-
Modular regulatory principles of large non-coding RNAs
-
doi: 10.1038/nature10887
-
Guttman, M., and Rinn, J. L. (2012). Modular regulatory principles of large non-coding RNAs. Nature 482, 339-346. doi: 10.1038/nature10887
-
(2012)
Nature
, vol.482
, pp. 339-346
-
-
Guttman, M.1
Rinn, J.L.2
-
56
-
-
0035704552
-
The thrifty phenotype hypothesis
-
doi: 10.1093/bmb/60.1.5
-
Hales, C. N. (2001). The thrifty phenotype hypothesis. Br. Med. Bull. 60, 5-20. doi: 10.1093/bmb/60.1.5
-
(2001)
Br. Med. Bull.
, vol.60
, pp. 5-20
-
-
Hales, C.N.1
-
57
-
-
0027442239
-
Tumour-suppressor activity of H19 RNA
-
doi: 10.1038/365764a0
-
Hao, Y., Crenshaw, T., Moulton, T., Newcomb, E., and Tycko, B. (1993). Tumour-suppressor activity of H19 RNA. Nature 365, 764-767. doi: 10.1038/365764a0
-
(1993)
Nature
, vol.365
, pp. 764-767
-
-
Hao, Y.1
Crenshaw, T.2
Moulton, T.3
Newcomb, E.4
Tycko, B.5
-
58
-
-
55949137722
-
Persistent epigenetic differences associated with prenatal exposure to famine in humans
-
doi: 10.1073/pnas.0806560105
-
Heijmans, B. T., Tobi, E. W., Stein, A. D., Putter, H., Blauw, G. J., Susser, E. S., et al. (2008). Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc. Natl. Acad. Sci. U.S.A. 105, 17046-17049. doi: 10.1073/pnas.0806560105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 17046-17049
-
-
Heijmans, B.T.1
Tobi, E.W.2
Stein, A.D.3
Putter, H.4
Blauw, G.J.5
Susser, E.S.6
-
59
-
-
84876935138
-
Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding
-
doi: 10.1016/j.cell.2013.03.043
-
Helwak, A., Kudla, G., Dudnakova, T., and Tollervey, D. (2013). Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding. Cell 153, 654-665. doi: 10.1016/j.cell.2013.03.043
-
(2013)
Cell
, vol.153
, pp. 654-665
-
-
Helwak, A.1
Kudla, G.2
Dudnakova, T.3
Tollervey, D.4
-
60
-
-
23044498447
-
Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels
-
doi: 10.1210/jc.2005-0158
-
Hussain, K., Cosgrove, K. E., Shepherd, R. M., Luharia, A., Smith, V. V., Kassem, S., et al. (2005). Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels. J. Clin. Endocrinol. Metab. 90, 4376-4382. doi: 10.1210/jc.2005-0158
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 4376-4382
-
-
Hussain, K.1
Cosgrove, K.E.2
Shepherd, R.M.3
Luharia, A.4
Smith, V.V.5
Kassem, S.6
-
61
-
-
33847185603
-
A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains.
-
doi: 10.1186/1471-2164-8-39.
-
Hutchinson, J. N., Ensminger, A. W., Clemson, C. M., Lynch, C. R., Lawrence, J. B., and Chess, A. (2007). A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics 8:39. doi: 10.1186/1471-2164-8-39
-
(2007)
BMC Genomics
, vol.8
, pp. 39
-
-
Hutchinson, J.N.1
Ensminger, A.W.2
Clemson, C.M.3
Lynch, C.R.4
Lawrence, J.B.5
Chess, A.6
-
62
-
-
0345505676
-
Genetic liability of type 1 diabetes and the onset age among 22, 650 young Finnish twin pairs: a nationwide follow-up study
-
doi: 10.2337/diabetes.52.4.1052
-
Hyttinen, V., Kaprio, J., Kinnunen, L., Koskenvuo, M., and Tuomilehto, J. (2003). Genetic liability of type 1 diabetes and the onset age among 22, 650 young Finnish twin pairs: a nationwide follow-up study. Diabetes 52, 1052-1055. doi: 10.2337/diabetes.52.4.1052
-
(2003)
Diabetes
, vol.52
, pp. 1052-1055
-
-
Hyttinen, V.1
Kaprio, J.2
Kinnunen, L.3
Koskenvuo, M.4
Tuomilehto, J.5
-
63
-
-
55949131420
-
Genomic imprinting mechanisms in mammals
-
doi: 10.1016/j.mrfmmm.2008.08.008
-
Ideraabdullah, F. Y., Vigneau, S., and Bartolomei, M. S. (2008). Genomic imprinting mechanisms in mammals. Mutat. Res. 647, 77-85. doi: 10.1016/j.mrfmmm.2008.08.008
-
(2008)
Mutat. Res.
, vol.647
, pp. 77-85
-
-
Ideraabdullah, F.Y.1
Vigneau, S.2
Bartolomei, M.S.3
-
64
-
-
0344429906
-
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
-
doi: 10.1038/sj.onc.1206928
-
Ji, P., Diederichs, S., Wang, W., Böing, S., Metzger, R., Schneider, P. M., et al. (2003). MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene 22, 8031-8041. doi: 10.1038/sj.onc.1206928
-
(2003)
Oncogene
, vol.22
, pp. 8031-8041
-
-
Ji, P.1
Diederichs, S.2
Wang, W.3
Böing, S.4
Metzger, R.5
Schneider, P.M.6
-
65
-
-
77954156503
-
The IG-DMR and the MEG3-DMR at human chromosome 14q32.2: hierarchical interaction and distinct functional properties as imprinting control centers.
-
doi: 10.1371/journal.pgen.1000992.s006.
-
Kagami, M., O'Sullivan, M. J., Green, A. J., Watabe, Y., Arisaka, O., Masawa, N., et al. (2010). The IG-DMR and the MEG3-DMR at human chromosome 14q32.2: hierarchical interaction and distinct functional properties as imprinting control centers. PLoS Genet. 6:e1000992. doi: 10.1371/journal.pgen.1000992.s006
-
(2010)
PLoS Genet.
, vol.6
-
-
Kagami, M.1
O'Sullivan, M.J.2
Green, A.J.3
Watabe, Y.4
Arisaka, O.5
Masawa, N.6
-
66
-
-
38649135702
-
Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes
-
doi: 10.1038/ng.2007.56
-
Kagami, M., Sekita, Y., Nishimura, G., Irie, M., Kato, F., Okada, M., et al. (2008). Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes. Nat. Genet. 40, 237-242. doi: 10.1038/ng.2007.56
-
(2008)
Nat. Genet.
, vol.40
, pp. 237-242
-
-
Kagami, M.1
Sekita, Y.2
Nishimura, G.3
Irie, M.4
Kato, F.5
Okada, M.6
-
67
-
-
84891856209
-
Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets
-
doi: 10.1016/j.cmet.2013.11.016
-
Kameswaran, V., Bramswig, N. C., McKenna, L. B., Penn, M., Schug, J., Hand, N. J., et al. (2014). Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets. Cell Metab. 19, 135-145. doi: 10.1016/j.cmet.2013.11.016
-
(2014)
Cell Metab.
, vol.19
, pp. 135-145
-
-
Kameswaran, V.1
Bramswig, N.C.2
McKenna, L.B.3
Penn, M.4
Schug, J.5
Hand, N.J.6
-
68
-
-
0034639657
-
The cell cycle control gene ZAC/PLAGL1 is imprinted - a strong candidate gene for transient neonatal diabetes
-
doi: 10.1093/hmg/9.3.453
-
Kamiya, M., Judson, H., Okazaki, Y., Kusakabe, M., Muramatsu, M., Takada, S., et al. (2000). The cell cycle control gene ZAC/PLAGL1 is imprinted - a strong candidate gene for transient neonatal diabetes. Hum. Mol. Genet. 9, 453-460. doi: 10.1093/hmg/9.3.453
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 453-460
-
-
Kamiya, M.1
Judson, H.2
Okazaki, Y.3
Kusakabe, M.4
Muramatsu, M.5
Takada, S.6
-
69
-
-
84892889808
-
Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin
-
doi: 10.1016/j.molcel.2013.11.012
-
Kaneko, S., Bonasio, R., Saldaña-Meyer, R., Yoshida, T., Son, J., Nishino, K., et al. (2014). Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin. Mol. Cell 53, 290-300. doi: 10.1016/j.molcel.2013.11.012
-
(2014)
Mol. Cell
, vol.53
, pp. 290-300
-
-
Kaneko, S.1
Bonasio, R.2
Saldaña-Meyer, R.3
Yoshida, T.4
Son, J.5
Nishino, K.6
-
70
-
-
71949099797
-
Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression
-
doi: 10.1128/MCB.01259-09
-
Kang, H. S., Kim, Y.-S., ZeRuth, G., Beak, J. Y., Gerrish, K., Kilic, G., et al. (2009). Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol. Cell. Biol. 29, 6366-6379. doi: 10.1128/MCB.01259-09
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 6366-6379
-
-
Kang, H.S.1
Kim, Y.-S.2
ZeRuth, G.3
Beak, J.Y.4
Gerrish, K.5
Kilic, G.6
-
71
-
-
33644749370
-
Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma
-
doi: 10.1093/hmg/ddl001
-
Kawakami, T., Chano, T., Minami, K., Okabe, H., Okada, Y., and Okamoto, K. (2006). Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma. Hum. Mol. Genet. 15, 821-830. doi: 10.1093/hmg/ddl001
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 821-830
-
-
Kawakami, T.1
Chano, T.2
Minami, K.3
Okabe, H.4
Okada, Y.5
Okamoto, K.6
-
72
-
-
67650921949
-
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
-
doi: 10.1073/pnas.0904715106
-
Khalil, A. M., Guttman, M., Huarte, M., Garber, M., Raj, A., Rivea Morales, D., et al. (2009). Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc. Natl. Acad. Sci. U.S.A. 106, 11667-11672. doi: 10.1073/pnas.0904715106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 11667-11672
-
-
Khalil, A.M.1
Guttman, M.2
Huarte, M.3
Garber, M.4
Raj, A.5
Rivea Morales, D.6
-
73
-
-
72449122779
-
Parental origin of sequence variants associated with complex diseases
-
doi: 10.1038/nature08625
-
Kong, A., Steinthorsdottir, V., Masson, G., Thorleifsson, G., Sulem, P., Besenbacher, S., et al. (2009). Parental origin of sequence variants associated with complex diseases. Nature 462, 868-874. doi: 10.1038/nature08625
-
(2009)
Nature
, vol.462
, pp. 868-874
-
-
Kong, A.1
Steinthorsdottir, V.2
Masson, G.3
Thorleifsson, G.4
Sulem, P.5
Besenbacher, S.6
-
74
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
doi: 10.1038/nbt1393
-
Kroon, E., Martinson, L. A., Kadoya, K., Bang, A. G., Kelly, O. G., Eliazer, S., et al. (2008). Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 26, 443-452. doi: 10.1038/nbt1393
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
Bang, A.G.4
Kelly, O.G.5
Eliazer, S.6
-
75
-
-
84866977211
-
Research resource: RNA-Seq reveals unique features of the pancreatic Β-cell transcriptome
-
doi: 10.1210/me.2012-1176
-
Ku, G. M., Kim, H., Vaughn, I. W., Hangauer, M. J., Myung Oh, C., German, M. S., et al. (2012). Research resource: RNA-Seq reveals unique features of the pancreatic Β-cell transcriptome. Mol. Endocrinol. 26, 1783-1792. doi: 10.1210/me.2012-1176
-
(2012)
Mol. Endocrinol.
, vol.26
, pp. 1783-1792
-
-
Ku, G.M.1
Kim, H.2
Vaughn, I.W.3
Hangauer, M.J.4
Myung Oh, C.5
German, M.S.6
-
76
-
-
84871060911
-
Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing
-
doi: 10.1126/science.1228110
-
Latos, P. A., Pauler, F. M., Koerner, M. V., Senergin, H. B., Hudson, Q. J., Stocsits, R. R., et al. (2012). Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing. Science 338, 1469-1472. doi: 10.1126/science.1228110
-
(2012)
Science
, vol.338
, pp. 1469-1472
-
-
Latos, P.A.1
Pauler, F.M.2
Koerner, M.V.3
Senergin, H.B.4
Hudson, Q.J.5
Stocsits, R.R.6
-
77
-
-
84875177348
-
X-inactivation, imprinting, and long noncoding RNAs in health and disease
-
doi: 10.1016/j.cell.2013.02.016
-
Lee, J. T., and Bartolomei, M. S. (2013). X-inactivation, imprinting, and long noncoding RNAs in health and disease. Cell 152, 1308-1323. doi: 10.1016/j.cell.2013.02.016
-
(2013)
Cell
, vol.152
, pp. 1308-1323
-
-
Lee, J.T.1
Bartolomei, M.S.2
-
78
-
-
0033609117
-
Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting
-
doi: 10.1073/pnas.96.9.5203
-
Lee, M. P., DeBaun, M. R., Mitsuya, K., Galonek, H. L., Brandenburg, S., Oshimura, M., et al. (1999). Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting. Proc. Natl. Acad. Sci. U.S.A. 96, 5203-5208. doi: 10.1073/pnas.96.9.5203
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 5203-5208
-
-
Lee, M.P.1
DeBaun, M.R.2
Mitsuya, K.3
Galonek, H.L.4
Brandenburg, S.5
Oshimura, M.6
-
79
-
-
0031046285
-
Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements
-
doi: 10.1038/ng0297-181
-
Lee, M. P., Hu, R. J., Johnson, L. A., and Feinberg, A. P. (1997). Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements. Nat. Genet. 15, 181-185. doi: 10.1038/ng0297-181
-
(1997)
Nat. Genet.
, vol.15
, pp. 181-185
-
-
Lee, M.P.1
Hu, R.J.2
Johnson, L.A.3
Feinberg, A.P.4
-
80
-
-
84898432405
-
Long non-coding RNA in health and disease
-
doi: 10.1007/s00109-014-1131-8
-
Maass, P. G., Luft, F. C., and Bähring, S. (2014). Long non-coding RNA in health and disease. J. Mol. Med. 92, 337-346. doi: 10.1007/s00109-014-1131-8
-
(2014)
J. Mol. Med.
, vol.92
, pp. 337-346
-
-
Maass, P.G.1
Luft, F.C.2
Bähring, S.3
-
81
-
-
84864688599
-
DGCR8 HITS-CLIP reveals novel functions for the Microprocessor
-
doi: 10.1038/nsmb.2344
-
Macias, S., Plass, M., Stajuda, A., Michlewski, G., Eyras, E., and Cáceres, J. F. (2012). DGCR8 HITS-CLIP reveals novel functions for the Microprocessor. Nat. Struct. Mol. Biol. 19, 760-766. doi: 10.1038/nsmb.2344
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 760-766
-
-
Macias, S.1
Plass, M.2
Stajuda, A.3
Michlewski, G.4
Eyras, E.5
Cáceres, J.F.6
-
82
-
-
0036487987
-
Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus
-
doi: 10.1007/s00439-001-0671-5
-
Mackay, D. J. G., Coupe, A.-M., Shield, J. P. H., Storr, J. N. P., Temple, I. K., and Robinson, D. O. (2002). Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus. Hum. Genet. 110, 139-144. doi: 10.1007/s00439-001-0671-5
-
(2002)
Hum. Genet.
, vol.110
, pp. 139-144
-
-
Mackay, D.J.G.1
Coupe, A.-M.2
Shield, J.P.H.3
Storr, J.N.P.4
Temple, I.K.5
Robinson, D.O.6
-
83
-
-
79960622503
-
Biogenesis and function of nuclear bodies
-
doi: 10.1016/j.tig.2011.05.006
-
Mao, Y. S., Zhang, B., and Spector, D. L. (2011). Biogenesis and function of nuclear bodies. Trends Genet. 27, 295-306. doi: 10.1016/j.tig.2011.05.006
-
(2011)
Trends Genet.
, vol.27
, pp. 295-306
-
-
Mao, Y.S.1
Zhang, B.2
Spector, D.L.3
-
84
-
-
2942560254
-
Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene
-
doi: 10.1038/nature02538
-
Martens, J. A., Laprade, L., and Winston, F. (2004). Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene. Nature 429, 571-574. doi: 10.1038/nature02538
-
(2004)
Nature
, vol.429
, pp. 571-574
-
-
Martens, J.A.1
Laprade, L.2
Winston, F.3
-
85
-
-
33646782348
-
Non-coding RNA
-
doi: 10.1093/hmg/ddl046
-
Mattick, J. S., and Makunin, I. V. (2006). Non-coding RNA. Hum. Mol. Genet. 15, R17-R29. doi: 10.1093/hmg/ddl046
-
(2006)
Hum. Mol. Genet.
, vol.15
-
-
Mattick, J.S.1
Makunin, I.V.2
-
86
-
-
78649842241
-
Genomics, type 2 diabetes, and obesity
-
doi: 10.1056/NEJMra0906948
-
McCarthy, M. I. (2010). Genomics, type 2 diabetes, and obesity. N. Engl. J. Med. 363, 2339-2350. doi: 10.1056/NEJMra0906948
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2339-2350
-
-
McCarthy, M.I.1
-
87
-
-
0032896076
-
Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis
-
doi: 10.1007/s001250051132
-
Medici, F., Hawa, M., Ianari, A., Pyke, D. A., and Leslie, R. D. (1999). Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis. Diabetologia 42, 146-150. doi: 10.1007/s001250051132
-
(1999)
Diabetologia
, vol.42
, pp. 146-150
-
-
Medici, F.1
Hawa, M.2
Ianari, A.3
Pyke, D.A.4
Leslie, R.D.5
-
88
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
doi: 10.1016/j.cell.2012.02.005
-
Mendell, J. T., and Olson, E. N. (2012). MicroRNAs in stress signaling and human disease. Cell 148, 1172-1187. doi: 10.1016/j.cell.2012.02.005
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
89
-
-
38649114329
-
Specific expression of long noncoding RNAs in the mouse brain
-
doi: 10.1073/pnas.0706729105
-
Mercer, T. R., Dinger, M. E., Sunkin, S. M., Mehler, M. F., and Mattick, J. S. (2008). Specific expression of long noncoding RNAs in the mouse brain. Proc. Natl. Acad. Sci. U.S.A. 105, 716-721. doi: 10.1073/pnas.0706729105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 716-721
-
-
Mercer, T.R.1
Dinger, M.E.2
Sunkin, S.M.3
Mehler, M.F.4
Mattick, J.S.5
-
91
-
-
33646265537
-
Limited evolutionary conservation of imprinting in the human placenta
-
doi: 10.1073/pnas.0511031103
-
Monk, D., Arnaud, P., Apostolidou, S., Hills, F. A., Kelsey, G., Stanier, P., et al. (2006). Limited evolutionary conservation of imprinting in the human placenta. Proc. Natl. Acad. Sci. U.S.A. 103, 6623-6628. doi: 10.1073/pnas.0511031103
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 6623-6628
-
-
Monk, D.1
Arnaud, P.2
Apostolidou, S.3
Hills, F.A.4
Kelsey, G.5
Stanier, P.6
-
92
-
-
84867070330
-
Human Β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
-
doi: 10.1016/j.cmet.2012.08.010
-
Morán, I., Akerman, I., van de Bunt, M., Xie, R., Benazra, M., Nammo, T., et al. (2012). Human Β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metab. 16, 435-448. doi: 10.1016/j.cmet.2012.08.010
-
(2012)
Cell Metab.
, vol.16
, pp. 435-448
-
-
Morán, I.1
Akerman, I.2
van de Bunt, M.3
Xie, R.4
Benazra, M.5
Nammo, T.6
-
93
-
-
84864033675
-
Malat1 is not an essential component of nuclear speckles in mice
-
doi: 10.1261/rna.033217.112
-
Nakagawa, S., Ip, J. Y., Shioi, G., Tripathi, V., Zong, X., Hirose, T., et al. (2012). Malat1 is not an essential component of nuclear speckles in mice. RNA 18, 1487-1499. doi: 10.1261/rna.033217.112
-
(2012)
RNA
, vol.18
, pp. 1487-1499
-
-
Nakagawa, S.1
Ip, J.Y.2
Shioi, G.3
Tripathi, V.4
Zong, X.5
Hirose, T.6
-
94
-
-
17744388101
-
Characterization of the genomic Xist locus in rodents reveals conservation of overall gene structure and tandem repeats but rapid evolution of unique sequence
-
doi: 10.1101/gr.174901
-
Nesterova, T. B., Slobodyanyuk, S. Y., Elisaphenko, E. A., Shevchenko, A. I., Johnston, C., Pavlova, M. E., et al. (2001). Characterization of the genomic Xist locus in rodents reveals conservation of overall gene structure and tandem repeats but rapid evolution of unique sequence. Genome Res. 11, 833-849. doi: 10.1101/gr.174901
-
(2001)
Genome Res.
, vol.11
, pp. 833-849
-
-
Nesterova, T.B.1
Slobodyanyuk, S.Y.2
Elisaphenko, E.A.3
Shevchenko, A.I.4
Johnston, C.5
Pavlova, M.E.6
-
95
-
-
84878507398
-
GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim.
-
doi: 10.1371/journal.pgen.1003532.
-
Nogueira, T. C., Paula, F. M., Villate, O., Colli, M. L., Moura, R. F., Cunha, D. A., et al. (2013). GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim. PLoS Genet. 9:e1003532. doi: 10.1371/journal.pgen.1003532
-
(2013)
PLoS Genet.
, vol.9
-
-
Nogueira, T.C.1
Paula, F.M.2
Villate, O.3
Colli, M.L.4
Moura, R.F.5
Cunha, D.A.6
-
96
-
-
0027322519
-
IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndrome
-
doi: 10.1038/ng0593-94
-
Ohlsson, R., Nyström, A., Pfeifer-Ohlsson, S., Töhönen, V., Hedborg, F., Schofield, P., et al. (1993). IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndrome. Nat. Genet. 4, 94-97. doi: 10.1038/ng0593-94
-
(1993)
Nat. Genet.
, vol.4
, pp. 94-97
-
-
Ohlsson, R.1
Nyström, A.2
Pfeifer-Ohlsson, S.3
Töhönen, V.4
Hedborg, F.5
Schofield, P.6
-
97
-
-
70450193472
-
Human genetics illuminates the paths to metabolic disease
-
doi: 10.1038/nature08532
-
O'Rahilly, S. (2009). Human genetics illuminates the paths to metabolic disease. Nature 462, 307-314. doi: 10.1038/nature08532
-
(2009)
Nature
, vol.462
, pp. 307-314
-
-
O'Rahilly, S.1
-
98
-
-
34249724529
-
Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.
-
doi: 10.1371/journal.pgen.0030065.
-
Parker-Katiraee, L., Carson, A. R., Yamada, T., Arnaud, P., Feil, R., Abu-Amero, S. N., et al. (2007). Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet. 3:e65. doi: 10.1371/journal.pgen.0030065
-
(2007)
PLoS Genet.
, vol.3
-
-
Parker-Katiraee, L.1
Carson, A.R.2
Yamada, T.3
Arnaud, P.4
Feil, R.5
Abu-Amero, S.N.6
-
99
-
-
45549097738
-
Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
-
doi: 10.1172/JCI33655
-
Park, J. H., Stoffers, D. A., Nicholls, R. D., and Simmons, R. A. (2008). Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J. Clin. Invest. 118, 2316-2324. doi: 10.1172/JCI33655
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2316-2324
-
-
Park, J.H.1
Stoffers, D.A.2
Nicholls, R.D.3
Simmons, R.A.4
-
100
-
-
84895806401
-
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
-
doi: 10.1038/ng.2870
-
Pasquali, L., Gaulton, K. J., Rodríguez-Seguí, S. A., Mularoni, L., Miguel-Escalada, I., Akerman, I., et al. (2014). Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants. Nat. Genet. 46, 136-143. doi: 10.1038/ng.2870
-
(2014)
Nat. Genet.
, vol.46
, pp. 136-143
-
-
Pasquali, L.1
Gaulton, K.J.2
Rodríguez-Seguí, S.A.3
Mularoni, L.4
Miguel-Escalada, I.5
Akerman, I.6
-
101
-
-
34248162440
-
Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs
-
doi: 10.1101/gr.6036807
-
Ponjavic, J., Ponting, C. P., and Lunter, G. (2007). Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs. Genome Res. 17, 556-565. doi: 10.1101/gr.6036807
-
(2007)
Genome Res.
, vol.17
, pp. 556-565
-
-
Ponjavic, J.1
Ponting, C.P.2
Lunter, G.3
-
102
-
-
80052343967
-
A genetically engineered human pancreatic Β cell line exhibiting glucose-inducible insulin secretion
-
doi: 10.1172/JCI58447
-
Ravassard, P., Hazhouz, Y., Pechberty, S., Bricout-Neveu, E., Armanet, M., Czernichow, P., et al. (2011). A genetically engineered human pancreatic Β cell line exhibiting glucose-inducible insulin secretion. J. Clin. Invest. 121, 3589-3597. doi: 10.1172/JCI58447
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3589-3597
-
-
Ravassard, P.1
Hazhouz, Y.2
Pechberty, S.3
Bricout-Neveu, E.4
Armanet, M.5
Czernichow, P.6
-
103
-
-
0032539468
-
Glucose tolerance in adults after prenatal exposure to famine
-
doi: 10.1016/S0140-6736(97)07244-9
-
Ravelli, A. C., van der Meulen, J. H., Michels, R. P., Osmond, C., Barker, D. J., Hales, C. N., et al. (1998). Glucose tolerance in adults after prenatal exposure to famine. Lancet 351, 173-177. doi: 10.1016/S0140-6736(97)07244-9
-
(1998)
Lancet
, vol.351
, pp. 173-177
-
-
Ravelli, A.C.1
van der Meulen, J.H.2
Michels, R.P.3
Osmond, C.4
Barker, D.J.5
Hales, C.N.6
-
104
-
-
84861904178
-
Genome regulation by long noncoding RNAs
-
doi: 10.1146/annurev-biochem-051410-092902
-
Rinn, J. L., and Chang, H. Y. (2012). Genome regulation by long noncoding RNAs. Annu. Rev. Biochem. 81, 145-166. doi: 10.1146/annurev-biochem-051410-092902
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 145-166
-
-
Rinn, J.L.1
Chang, H.Y.2
-
105
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
doi: 10.1016/j.cell.2007.05.022
-
Rinn, J. L., Kertesz, M., Wang, J. K., Squazzo, S. L., Xu, X., Brugmann, S. A., et al. (2007). Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129, 1311-1323. doi: 10.1016/j.cell.2007.05.022
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
Kertesz, M.2
Wang, J.K.3
Squazzo, S.L.4
Xu, X.5
Brugmann, S.A.6
-
106
-
-
33746911576
-
The Dutch famine and its long-term consequences for adult health
-
doi: 10.1016/j.earlhumdev.2006.07.001
-
Roseboom, T., de Rooij, S., and Painter, R. (2006). The Dutch famine and its long-term consequences for adult health. Early Hum. Dev. 82, 485-491. doi: 10.1016/j.earlhumdev.2006.07.001
-
(2006)
Early Hum. Dev.
, vol.82
, pp. 485-491
-
-
Roseboom, T.1
de Rooij, S.2
Painter, R.3
-
107
-
-
84863207933
-
Reduced insulin exocytosis in human pancreatic Β-cells with gene variants linked to type 2 diabetes
-
doi: 10.2337/db11-1516
-
Rosengren, A. H., Braun, M., Mahdi, T., Andersson, S. A., Travers, M. E., Shigeto, M., et al. (2012). Reduced insulin exocytosis in human pancreatic Β-cells with gene variants linked to type 2 diabetes. Diabetes 61, 1726-1733. doi: 10.2337/db11-1516
-
(2012)
Diabetes
, vol.61
, pp. 1726-1733
-
-
Rosengren, A.H.1
Braun, M.2
Mahdi, T.3
Andersson, S.A.4
Travers, M.E.5
Shigeto, M.6
-
108
-
-
0034663920
-
The Dlk1 and Gtl2 genes are linked and reciprocally imprinted
-
doi: 10.1101/gad.14.16.1997
-
Schmidt, J. V., Matteson, P. G., Jones, B. K., Guan, X. J., and Tilghman, S. M. (2000). The Dlk1 and Gtl2 genes are linked and reciprocally imprinted. Genes Dev. 14, 1997-2002. doi: 10.1101/gad.14.16.1997
-
(2000)
Genes Dev.
, vol.14
, pp. 1997-2002
-
-
Schmidt, J.V.1
Matteson, P.G.2
Jones, B.K.3
Guan, X.J.4
Tilghman, S.M.5
-
109
-
-
77957342306
-
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.
-
DIAGRAM Consortium MAGIC investigators doi: 10.1371/journal.pgen.1001058.
-
Segrè, A. V., DIAGRAM Consortium, MAGIC investigators, Groop, L., Mootha, V. K., Daly, M. J., et al. (2010). Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet. 6:e1001058. doi: 10.1371/journal.pgen.1001058
-
(2010)
PLoS Genet.
, vol.6
-
-
Segrè, A.V.1
Groop, L.2
Mootha, V.K.3
Daly, M.J.4
-
110
-
-
4644253753
-
A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain
-
doi: 10.1101/gr.2743304
-
Seitz, H., Royo, H., Bortolin, M.-L., Lin, S.-P., Ferguson-Smith, A. C., and Cavaille, J. (2004). A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res. 14, 1741-1748. doi: 10.1101/gr.2743304
-
(2004)
Genome Res.
, vol.14
, pp. 1741-1748
-
-
Seitz, H.1
Royo, H.2
Bortolin, M.-L.3
Lin, S.-P.4
Ferguson-Smith, A.C.5
Cavaille, J.6
-
111
-
-
38649091005
-
Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta
-
doi: 10.1038/ng.2007.51
-
Sekita, Y., Wagatsuma, H., Nakamura, K., Ono, R., Kagami, M., Wakisaka, N., et al. (2008). Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta. Nat. Genet. 40, 243-248. doi: 10.1038/ng.2007.51
-
(2008)
Nat. Genet.
, vol.40
, pp. 243-248
-
-
Sekita, Y.1
Wagatsuma, H.2
Nakamura, K.3
Ono, R.4
Kagami, M.5
Wakisaka, N.6
-
112
-
-
0031394680
-
Aetiopathology and genetic basis of neonatal diabetes
-
doi: 10.1136/fn.76.1.F39
-
Shield, J. P., Gardner, R. J., Wadsworth, E. J., Whiteford, M. L., James, R. S., Robinson, D. O., et al. (1997). Aetiopathology and genetic basis of neonatal diabetes. Arch. Dis. Child. Fetal Neonatal Ed. 76, F39-F42. doi: 10.1136/fn.76.1.F39
-
(1997)
Arch. Dis. Child. Fetal Neonatal Ed.
, vol.76
-
-
Shield, J.P.1
Gardner, R.J.2
Wadsworth, E.J.3
Whiteford, M.L.4
James, R.S.5
Robinson, D.O.6
-
113
-
-
79957607662
-
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
-
doi: 10.1038/ng.833
-
Small, K. S., Hedman, A. K., Grundberg, E., Nica, A. C., Thorleifsson, G., Kong, A., et al. (2011). Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat. Genet. 43, 561-564. doi: 10.1038/ng.833
-
(2011)
Nat. Genet.
, vol.43
, pp. 561-564
-
-
Small, K.S.1
Hedman, A.K.2
Grundberg, E.3
Nica, A.C.4
Thorleifsson, G.5
Kong, A.6
-
114
-
-
0027245963
-
Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation
-
doi: 10.1016/0092-8674(93)90252-L
-
Smas, C. M., and Sul, H. S. (1993). Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell 73, 725-734. doi: 10.1016/0092-8674(93)90252-L
-
(1993)
Cell
, vol.73
, pp. 725-734
-
-
Smas, C.M.1
Sul, H.S.2
-
115
-
-
0030955765
-
Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain
-
doi: 10.1093/emboj/16.10.2814
-
Spengler, D., Villalba, M., Hoffmann, A., Pantaloni, C., Houssami, S., Bockaert, J., et al. (1997). Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain. EMBO J. 16, 2814-2825. doi: 10.1093/emboj/16.10.2814
-
(1997)
EMBO J.
, vol.16
, pp. 2814-2825
-
-
Spengler, D.1
Villalba, M.2
Hoffmann, A.3
Pantaloni, C.4
Houssami, S.5
Bockaert, J.6
-
116
-
-
0033043426
-
Role of a 461-bp G-rich repetitive element in H19 transgene imprinting
-
doi: 10.1007/s004270050248
-
Stadnick, M. P., Pieracci, F. M., Cranston, M. J., Taksel, E., Thorvaldsen, J. L., and Bartolomei, M. S. (1999). Role of a 461-bp G-rich repetitive element in H19 transgene imprinting. Dev. Genes Evol. 209, 239-248. doi: 10.1007/s004270050248
-
(1999)
Dev. Genes Evol.
, vol.209
, pp. 239-248
-
-
Stadnick, M.P.1
Pieracci, F.M.2
Cranston, M.J.3
Taksel, E.4
Thorvaldsen, J.L.5
Bartolomei, M.S.6
-
117
-
-
77952425747
-
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
-
doi: 10.1038/nature09017
-
Stadtfeld, M., Apostolou, E., Akutsu, H., Fukuda, A., Follett, P., Natesan, S., et al. (2010). Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 465, 175-181. doi: 10.1038/nature09017
-
(2010)
Nature
, vol.465
, pp. 175-181
-
-
Stadtfeld, M.1
Apostolou, E.2
Akutsu, H.3
Fukuda, A.4
Follett, P.5
Natesan, S.6
-
118
-
-
33847698971
-
The relationship between non-protein-coding DNA and eukaryotic complexity
-
doi: 10.1002/bies.20544
-
Taft, R. J., Pheasant, M., and Mattick, J. S. (2007). The relationship between non-protein-coding DNA and eukaryotic complexity. Bioessays 29, 288-299. doi: 10.1002/bies.20544
-
(2007)
Bioessays
, vol.29
, pp. 288-299
-
-
Taft, R.J.1
Pheasant, M.2
Mattick, J.S.3
-
119
-
-
0033860008
-
Transient neonatal diabetes: widening the understanding of the etiopathogenesis of diabetes
-
doi: 10.2337/diabetes.49.8.1359
-
Temple, I. K., Gardner, R. J., Mackay, D. J., Barber, J. C., Robinson, D. O., and Shield, J. P. (2000). Transient neonatal diabetes: widening the understanding of the etiopathogenesis of diabetes. Diabetes 49, 1359-1366. doi: 10.2337/diabetes.49.8.1359
-
(2000)
Diabetes
, vol.49
, pp. 1359-1366
-
-
Temple, I.K.1
Gardner, R.J.2
Mackay, D.J.3
Barber, J.C.4
Robinson, D.O.5
Shield, J.P.6
-
120
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
doi: 10.1038/nature09270
-
Teslovich, T. M., Musunuru, K., Smith, A. V., Edmondson, A. C., Stylianou, I. M., Koseki, M., et al. (2010). Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713. doi: 10.1038/nature09270
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
Edmondson, A.C.4
Stylianou, I.M.5
Koseki, M.6
-
121
-
-
34548208608
-
SnapShot: imprinted gene clusters.
-
doi: 10.1016/j.cell.2007.08.033.
-
Thorvaldsen, J. L., and Bartolomei, M. S. (2007). SnapShot: imprinted gene clusters. Cell 130:958. doi: 10.1016/j.cell.2007.08.033
-
(2007)
Cell
, vol.130
, pp. 958
-
-
Thorvaldsen, J.L.1
Bartolomei, M.S.2
-
122
-
-
30944440220
-
High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12
-
doi: 10.1016/j.ygeno.2005.09.018
-
Tierling, S., Dalbert, S., Schoppenhorst, S., Tsai, C.-E., Oliger, S., Ferguson-Smith, A. C., et al. (2006). High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12. Genomics 87, 225-235. doi: 10.1016/j.ygeno.2005.09.018
-
(2006)
Genomics
, vol.87
, pp. 225-235
-
-
Tierling, S.1
Dalbert, S.2
Schoppenhorst, S.3
Tsai, C.-E.4
Oliger, S.5
Ferguson-Smith, A.C.6
-
123
-
-
0030457199
-
FA1 immunoreactivity in endocrine tumours and during development of the human fetal pancreas; negative correlation with glucagon expression
-
doi: 10.1007/BF02473268
-
Tornehave, D., Jensen, C. H., Teisner, B., and Larsson, L. I. (1996). FA1 immunoreactivity in endocrine tumours and during development of the human fetal pancreas; negative correlation with glucagon expression. Histochem. Cell Biol. 106, 535-542. doi: 10.1007/BF02473268
-
(1996)
Histochem. Cell Biol.
, vol.106
, pp. 535-542
-
-
Tornehave, D.1
Jensen, C.H.2
Teisner, B.3
Larsson, L.I.4
-
124
-
-
84874427659
-
Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets
-
doi: 10.2337/db12-0819/-/DC1
-
Travers, M. E., Mackay, D. J. G., Dekker Nitert, M., Morris, A. P., Lindgren, C. M., Berry, A., et al. (2013). Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets. Diabetes 62, 987-992. doi: 10.2337/db12-0819/-/DC1
-
(2013)
Diabetes
, vol.62
, pp. 987-992
-
-
Travers, M.E.1
Mackay, D.J.G.2
Dekker Nitert, M.3
Morris, A.P.4
Lindgren, C.M.5
Berry, A.6
-
125
-
-
77956927823
-
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
-
doi: 10.1016/j.molcel.2010.08.011
-
Tripathi, V., Ellis, J. D., Shen, Z., Song, D. Y., Pan, Q., Watt, A. T., et al. (2010). The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol. Cell 39, 925-938. doi: 10.1016/j.molcel.2010.08.011
-
(2010)
Mol. Cell
, vol.39
, pp. 925-938
-
-
Tripathi, V.1
Ellis, J.D.2
Shen, Z.3
Song, D.Y.4
Pan, Q.5
Watt, A.T.6
-
126
-
-
84455206362
-
Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
-
doi: 10.1016/j.cell.2011.11.055
-
Ulitsky, I., Shkumatava, A., Jan, C. H., Sive, H., and Bartel, D. P. (2011). Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell 147, 1537-1550. doi: 10.1016/j.cell.2011.11.055
-
(2011)
Cell
, vol.147
, pp. 1537-1550
-
-
Ulitsky, I.1
Shkumatava, A.2
Jan, C.H.3
Sive, H.4
Bartel, D.P.5
-
127
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
doi: 10.1038/ng.208
-
Unoki, H., Takahashi, A., Kawaguchi, T., Hara, K., Horikoshi, M., Andersen, G., et al. (2008). SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat. Genet. 40, 1098-1102. doi: 10.1038/ng.208
-
(2008)
Nat. Genet.
, vol.40
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
Hara, K.4
Horikoshi, M.5
Andersen, G.6
-
128
-
-
34447322033
-
Tissue-specific imprinting of the ZAC/PLAGL1 tumour suppressor gene results from variable utilization of monoallelic and biallelic promoters
-
doi: 10.1093/hmg/ddm041
-
Valleley, E. M., Cordery, S. F., and Bonthron, D. T. (2007). Tissue-specific imprinting of the ZAC/PLAGL1 tumour suppressor gene results from variable utilization of monoallelic and biallelic promoters. Hum. Mol. Genet. 16, 972-981. doi: 10.1093/hmg/ddm041
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 972-981
-
-
Valleley, E.M.1
Cordery, S.F.2
Bonthron, D.T.3
-
129
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
doi: 10.1038/ng.609
-
Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., et al. (2010). Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat. Genet. 42, 579-589. doi: 10.1038/ng.609
-
(2010)
Nat. Genet.
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
Morris, A.P.4
Dina, C.5
Welch, R.P.6
-
130
-
-
73349115848
-
The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
-
doi: 10.1038/ng.493
-
Wallace, C., Smyth, D. J., Maisuria-Armer, M., Walker, N. M., Todd, J. A., and Clayton, D. G. (2010). The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes. Nat. Genet. 42, 68-71. doi: 10.1038/ng.493
-
(2010)
Nat. Genet.
, vol.42
, pp. 68-71
-
-
Wallace, C.1
Smyth, D.J.2
Maisuria-Armer, M.3
Walker, N.M.4
Todd, J.A.5
Clayton, D.G.6
-
131
-
-
59349087552
-
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs
-
doi: 10.1016/j.cell.2008.12.023
-
Weinmann, L., Höck, J., Ivacevic, T., Ohrt, T., Mütze, J., Schwille, P., et al. (2009). Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell 136, 496-507. doi: 10.1016/j.cell.2008.12.023
-
(2009)
Cell
, vol.136
, pp. 496-507
-
-
Weinmann, L.1
Höck, J.2
Ivacevic, T.3
Ohrt, T.4
Mütze, J.5
Schwille, P.6
-
132
-
-
0028054862
-
Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells
-
Yada, T., Sakurada, M., Ihida, K., Nakata, M., Murata, F., Arimura, A., et al. (1994). Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells. J. Biol. Chem. 269, 1290-1293.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1290-1293
-
-
Yada, T.1
Sakurada, M.2
Ihida, K.3
Nakata, M.4
Murata, F.5
Arimura, A.6
-
133
-
-
81055140863
-
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs
-
doi: 10.1016/j.cell.2011.08.054
-
Yang, L., Lin, C., Liu, W., Zhang, J., Ohgi, K. A., Grinstein, J. D., et al. (2011). ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell 147, 773-788. doi: 10.1016/j.cell.2011.08.054
-
(2011)
Cell
, vol.147
, pp. 773-788
-
-
Yang, L.1
Lin, C.2
Liu, W.3
Zhang, J.4
Ohgi, K.A.5
Grinstein, J.D.6
-
134
-
-
50449085998
-
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
-
doi: 10.1038/ng.207
-
Yasuda, K., Miyake, K., Horikawa, Y., Hara, K., Osawa, H., Furuta, H., et al. (2008). Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat. Genet. 40, 1092-1097. doi: 10.1038/ng.207
-
(2008)
Nat. Genet.
, vol.40
, pp. 1092-1097
-
-
Yasuda, K.1
Miyake, K.2
Horikawa, Y.3
Hara, K.4
Osawa, H.5
Furuta, H.6
-
135
-
-
84884765608
-
The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription
-
doi: 10.1210/me.2013-1117
-
ZeRuth, G. T., Takeda, Y., and Jetten, A. M. (2013). The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription. Mol. Endocrinol. 27, 1692-1705. doi: 10.1210/me.2013-1117
-
(2013)
Mol. Endocrinol.
, vol.27
, pp. 1692-1705
-
-
ZeRuth, G.T.1
Takeda, Y.2
Jetten, A.M.3
-
136
-
-
84864315112
-
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult
-
doi: 10.1016/j.celrep.2012.06.003
-
Zhang, B., Arun, G., Mao, Y. S., Lazar, Z., and Hung, G. (2012). The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. Cell Rep. 2, 111-123. doi: 10.1016/j.celrep.2012.06.003
-
(2012)
Cell Rep.
, vol.2
, pp. 111-123
-
-
Zhang, B.1
Arun, G.2
Mao, Y.S.3
Lazar, Z.4
Hung, G.5
-
137
-
-
84891898005
-
Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus
-
doi: 10.1083/jcb.201304152
-
Zhang, H., Zeitz, M. J., Wang, H., Niu, B., Ge, S., Li, W., et al. (2014). Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus. J. Cell Biol. 204, 61-75. doi: 10.1083/jcb.201304152
-
(2014)
J. Cell Biol.
, vol.204
, pp. 61-75
-
-
Zhang, H.1
Zeitz, M.J.2
Wang, H.3
Niu, B.4
Ge, S.5
Li, W.6
-
138
-
-
17844397712
-
Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors
-
doi: 10.1210/jc.2004-1848
-
Zhao, J., Dahle, D., Zhou, Y., Zhang, X., and Klibanski, A. (2005). Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. J. Clin. Endocrinol. Metab. 90, 2179-2186. doi: 10.1210/jc.2004-1848
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 2179-2186
-
-
Zhao, J.1
Dahle, D.2
Zhou, Y.3
Zhang, X.4
Klibanski, A.5
-
139
-
-
78650253763
-
Genome-wide identification of polycomb-associated RNAs by RIP-seq
-
doi: 10.1016/j.molcel.2010.12.011
-
Zhao, J., Ohsumi, T. K., Kung, J. T., Ogawa, Y., Grau, D. J., Sarma, K., et al. (2010). Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol. Cell 40, 939-953. doi: 10.1016/j.molcel.2010.12.011
-
(2010)
Mol. Cell
, vol.40
, pp. 939-953
-
-
Zhao, J.1
Ohsumi, T.K.2
Kung, J.T.3
Ogawa, Y.4
Grau, D.J.5
Sarma, K.6
-
140
-
-
84861156701
-
MEG3 noncoding RNA: a tumor suppressor
-
doi: 10.1530/JME-12-0008
-
Zhou, Y., Zhang, X., and Klibanski, A. (2012). MEG3 noncoding RNA: a tumor suppressor. J. Mol. Endocrinol. 48, R45-R53. doi: 10.1530/JME-12-0008
-
(2012)
J. Mol. Endocrinol.
, vol.48
-
-
Zhou, Y.1
Zhang, X.2
Klibanski, A.3
-
141
-
-
34548304069
-
Activation of p53 by MEG3 non-coding RNA
-
doi: 10.1074/jbc.M702029200
-
Zhou, Y., Zhong, Y., Wang, Y., Zhang, X., Batista, D. L., Gejman, R., et al. (2007). Activation of p53 by MEG3 non-coding RNA. J. Biol. Chem. 282, 24731-24742. doi: 10.1074/jbc.M702029200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24731-24742
-
-
Zhou, Y.1
Zhong, Y.2
Wang, Y.3
Zhang, X.4
Batista, D.L.5
Gejman, R.6
-
142
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
doi: 10.1038/414782a
-
Zimmet, P., Alberti, K. G., and Shaw, J. (2001). Global and societal implications of the diabetes epidemic. Nature 414, 782-787. doi: 10.1038/414782a
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
|