Role of a 461-bp G-rich repetitive element in H19 transgene imprinting

Development Genes and Evolution

Volumn 209, Issue 4, 1999, Pages 239-248

  Stadnick, Michael P ^a   Pieracci, Fredric M ^a   Cranston, Melanie J ^a   Taksel, Eva ^a   Thorvaldsen, Joanne L ^a   Bartolomei, Marisa S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

DNA methylation; H19; Imprinting; Repetitive elements; Transgenes

Indexed keywords

DNA; GUANINE; REPETITIVE DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; EMBRYO; FEMALE; GENETIC CONSERVATION; GENOME IMPRINTING; HUMAN; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; TRANSGENE;

ANIMALS; BASE COMPOSITION; BASE SEQUENCE; DNA; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOMIC IMPRINTING; GUANINE; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED STRAINS; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, UNTRANSLATED; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSGENES;

ANIMALIA; MAMMALIA;

EID: 0033043426     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004270050248     Document Type: Article

References (42)

1. Ainscough JF-X, Koide T, Tuda M, Barton S, Surani MA (1997) Imprinting of Igf2 and H19 from a 130 kb YAC transgene. Development 124: 3621-3632
2. Auffray C, Rougeon F (1980) Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur J Biochem 107: 303-314
3. Bartolomei MS, Tilghman SM (1997) Genomic imprinting in mammals. Annu Rev Genet 31: 493-525
4. Bartolomei MS, Zemel S, Tilghman SM (1991) Parental imprinting of the mouse H19 gene. Nature 351: 153-155
5. Bartolomei MS, Webber AL, Brunkow ME, Tilghman SM (1993) Epigenetic mechanisms underlying the imprinting of the mouse H19 gene. Genes Dev 7: 1663-1673
6. Brockdorff N, Ashworth A, Kay GF, McCabe VM, Norris DP, Cooper PJ, Swift S, Rastan S (1992) The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 71: 515-526
7. Brown CJ, Hendrich BD, Rupert JL, Lafreniere RG, Xing Y, Lawrence J, Williard HF (1992) The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell 71: 527-542
8. Brunkow ME, Tilghman SM (1991) Ectopic expression of the H19 gene in mice causes prenatal lethality. Genes Dev 5: 1092-1101
9. Dorer DR, Henikoff S (1994) Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila. Cell 77: 993-1002
10. Efstratiadis A (1994) Parental imprinting of autosomal mammalian genes. Curr Opin Genet Dev 4: 265-280
11. Elson DA, Bartolomei MS (1997) A 5' differentially methylated sequence and the 3' flanking region are necessary for H19 transgene imprinting. Mol Cell Biol 17: 309-317
12. Ferguson-Smith AS, Sasaki H, Cattanach BM, Surani MA (1993) Parental-origin-specific epigenetic modification of the mouse H19 gene. Nature 362: 751-754
13. Garrick D, Fiering S, Martin DIK, Whitelaw E (1998) Repeat-induced gene silencing in mammals. Nat Genet 18: 56-59
14. Gottschling DE, Aparicio OM, Billington BL, Zakian VA (1990) Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription. Cell 63: 751-762
15. Hammond-Kosack MCU, Kilpatrick MW, Docherty K (1993) The human insulin gene-linked polymorphic region adopts a G-quartet structure in chromatin assembled in vitro. J Mol Endocrin 10: 121-126
16. Hatada I, Mukai T (1995) Genomic imprinting of p57/KIP2, a cyclin-dependent kinase inhibitor, in mouse. Nat Genet 11: 204-206
17. Hayashizaki Y, Shibata H, Hirotsune S, Sugino H, Okazaki Y, Sasaki N, Hirose K, Imoto H, Okuizumi H, Muramatsu M, Komatsubara H, Shiroishi T, Moriwaki K, Katsuki M, Hatano N, Sasaki H, Ueda T, Mise N, Takagi N, Plass C, Chapman VM (1994) Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method. Nat Genet 6: 33-40
18. Jinno Y, Sengoku K, Nakao M, Tamate K, Miyamoto T, Matsuzaka T, Sutcliffe JS, Anan T, Takuma N, Nishiwaki K, Ikeda Y, Ishimaru T, Ishikawa M, Niikawa N (1996) Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locus. Hum Mol Genet 5: 1155-1161
19. Leighton PA, Ingram RS, Eggenschwiler J, Efstratiadis A, Tilghman SM (1995) Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 375: 34-39
20. Li E, Beard C, Jaenisch R (1993) Role for DNA methylation in genomic imprinting. Nature 366: 362-365
21. Lyko F, Brenton JD, Surani MA, Paro R (1997) An imprinting element from the mouse H19 locus functions as a silencer in Drosophila. Nat Genet 16: 171-173
22. Moore T, Constancia M, Zubair M, Bailleul B, Feil R, Sasaki H, Reik W (1997) Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2. Proc Natl Acad Sci USA 94: 12509-12514
23. Murchie AIH, Lilley DMJ (1992) Retinoblastoma susceptibility genes contain 5' sequences with a high propensity to form guanine-tetra structures. Nucleic Acids Res 20: 49-53
24. Neumann B, Kubicka P, Barlow DP (1995) Characteristics of imprinted genes. Nat Genet 9: 12-13
25. Olek A, Walter J (1997) The pre-implantation ontogeny of the H19 methylation imprint. Nat Genet 17: 275-276
26. Overall M, Bakker M, Spencer J, Parker N, Smith P, Dziadek M (1997) Genomic imprinting in the rat: linkages of Igf2 and H19 genes and opposite parental allele-specific expression during embryogenesis. Genomics 45: 416-420
27. Pal-Bhadra M, Bhadra U, Birchler JA (1997) Cosuppression in Drosophila: gene silencing of alcohol dehydrogenase by white-Adh transgenes is polycomb dependent. Cell 90: 479-490
28. Pfeifer K, Leighton P, Tilghman SM (1996) The structural gene of H19 is required for transgene imprinting. Proc Natl Acad Sci USA 93: 13876-13883
29. Rachmilewitz J, Goshen R, Ariel I, Schneider T, de Groot N, Hochberg A (1992) Parental imprinting of the human H19 gene. FEBS 309: 25-28
30. Razin A, Cedar H (1994) DNA methylation and genomic imprinting. Cell 77: 473-476
31. Ripoche M-A, Chantai K, Poirier F, Dandolo L (1997) Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element. Genes Dev 11: 1596-1604
32. Sen W, Gilbert W (1988) Formation of parallel four-stranded complexes by guanine-rich motifs for meiosis. Nature 334: 364-366
33. Solter D (1988) Differential imprinting and expression of maternal and paternal genomes. Ann Rev Genet 22: 127-146
34. Southern EM (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 98: 503-517
35. Stoger R, Kubicka P, Liu C-G, Kafri T, Razin A, Cedar H, Barlow DP (1993) Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 73: 61-71
36. Tremblay KD, Saam JR, Ingram RS, Tilghman SM, Bartolomei MS (1995) A paternal-specific methylation imprint marks the alleles of the mouse H19 gene. Nat Genet 9: 407-413
37. Tremblay KD, Duran KL, Bartolomei MS (1997) A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development. Mol Cell Biol 17: 4322-4329
38. Wolffe AP (1998) When more is less. Nat Genet 18: 5-6
39. Wutz A, Smrzka OW, Schweifer N, Schellander K, Wagner EF, Barlow DP (1997) Imprinted expression of the Igf2r gene depends on an intronic CpG island. Nature 389: 745-749
40. Yoo-Warren H, Pachnis V, Ingram RS, Tilghman SM (1988) Two regulatory domains flank the mouse H19 gene. Mol Cell Biol 8: 4707-4715
41. Zhang Y, Tycko B (1992) Monoallelic expression of the human H19 gene. Nat Genet 1: 40-44
42. Zhang Y, Shields T, Crenshaw T, Hao Y, Moulton T, Tycko B (1993) Imprinting of human H19; allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am J Hum Genet 53: 113-124