Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets

Diabetes

Volumn 62, Issue 3, 2013, Pages 987-992

  Travers, Mary E ^a   Mackay, Deborah J G ^a   Nitert, Marloes Dekker ^b,c   Morris, Andrew P ^d   Lindgren, Cecilia M ^a,c,d   Berry, Andrew ^e,f   Johnson, Paul R ^a,f   Hanley, Neil ^e,f   Groop, Leif C ^c   McCarthy, Mark I ^a,d,f   Gloyna, Anna L ^a,f  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c LUND UNIVERSITY DIABETES CENTRE   (Sweden)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1C; POTASSIUM CHANNEL KCNQ1;

ALLELE; ARTICLE; CHROMOSOME; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA METHYLATION; FETUS; GENE EXPRESSION; GENE LOCUS; GENETIC VARIABILITY; GENOME IMPRINTING; GENOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PYROSEQUENCING; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; CHROMOSOMES, HUMAN, PAIR 11; COHORT STUDIES; CYCLIN-DEPENDENT KINASE INHIBITOR P57; DIABETES MELLITUS, TYPE 2; DNA METHYLATION; FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC ASSOCIATION STUDIES; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GREAT BRITAIN; HUMANS; INTRONS; ISLETS OF LANGERHANS; KCNQ1 POTASSIUM CHANNEL; PANCREAS; POLYMORPHISM, SINGLE NUCLEOTIDE; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 84874427659     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0819     Document Type: Article

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