Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac

Molecular Brain Research

Volumn 69, Issue 2, 1999, Pages 290-294

  Ciani, Elisabetta ^a   Hoffmann, Anke ^a   Schmidt, Peer ^a   Journot, Laurent ^b   Spengler, Dietmar ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b CCIPE   (France)

Author keywords

Apoptosis; Differentiation; Ischemia; p53; PAC1 R; Zac

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; PROTEIN P53; SECRETIN; VASOACTIVE INTESTINAL POLYPEPTIDE; ZINC FINGER PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL DIFFERENTIATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE INDUCTION; NONHUMAN; PRIORITY JOURNAL; SWINE; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CELL CYCLE; CELL DIFFERENTIATION; GENES, P53; HUMANS; NERVE TISSUE PROTEINS; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; RECEPTORS, PITUITARY HORMONE; ZINC FINGERS;

EID: 0033055126     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00116-3     Document Type: Article

References (19)

1. Arimura A. Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous system. Jpn. J. Physiol. 48:1998;301-331.
2. Arimura A., Shioda S. Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interactions. Front. Neuroendocrinol. 16:1995;53-88.
3. Arimura A., Somogyvari-Vigh A. PACAP functions as a neurotrophic factor. Ann. NY Acad. Sci. 739:1994;228-243.
4. Deutsch P., Sun Y. The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth. J. Biol. Chem. 267:1992;5108-5113.
5. DiCicco-Bloom E., Deutsch P. Pituitary adenylate cyclase activating polypeptide (PACAP) potently stimulates mitosis, neuritogenesis and survival in cultured rat sympathetic neuroblasts. Regul. Pept. 37:1992;319-325.
6. Du C., Hu R., Csernansky C., Hsu C., Choi D. Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis? J. Cereb. Blood Flow Metab. 16:1996;195-210.
7. Gillardon F., Hata R., Hossmann K.-A. Delayed up-regulation of Zac1 and PACAP type I receptor after transient focal cerebral ischemia in mice. Mol. Brain Res. 61:1998;207-210.
8. Hughes P., Alexi T., Schreiber S. A role for the tumour suppressor gene p53 in regulating neuronal apoptosis. NeuroReport. 8:1997;V-XII.
9. Kass S.U., Pruss D., Wolffe A.P. How does DNA methylation repress transcription? Trends Genet. 13:1997;444-449.
10. Koistinaho J., Hökfelt T. Altered gene expression in brain ischemia. NeuroReport. 8:1997;I-VIII.
11. Lu N.R., DiCicco-Bloom E.M. Pituitary adenylate cyclase-activating polypeptide is an autocrine inhibitor of mitosis in cultured cortical precursor cells. Proc. Natl. Acad. Sci. U.S.A. 94:1997;3357-3362.
12. MacManus J., Linnik M. Gene expression induced by cerebral ischemia: an apoptotic perspective. J. Cereb. Blood Flow Metab. 17:1997;815-832.
13. Rogel A., Popliker M., Webb C.G., Oren M. p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors. Mol. Cell Biol. 5:1985;2851-2855.
14. Ross M. Cell division and the nervous system: regulating the cycle from neural differentiation to death. Trends Neurosci. 19:1996;62-68.
15. Sakhi S., Bruce A., Sun N., Tocco G., Baudry M., Schreiber S. p53 induction is associated with neuronal damage in the central nervous system. Proc. Natl. Acad. Sci. U.S.A. 91:1994;7525-7529.
16. Spengler D., Villaba M., Hoffmann A., Pantaloni C., Houssami S., Bockaert J., Journot L. Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain. EMBO J. 16:1997;2814-2825.
17. Spengler D., Waeber C., Pantaloni C., Holsboer F., Bockaert J., Seeburg P., Journot L. Differential signal transduction by five splice variants of the PACAP receptor. Nature. 365:1993;170-175.
18. Uchida D., Arimura A., Somogyvari-Vigh A., Shioda S., Banks W. Prevention of ischemia-induced death of hippocampal neurons by pituitary adenylate cyclase activating polypeptide. Brain Res. 736:1996;280-286.
19. Waschek J.A., Casillas R.A., Nguyen T.B., DiCicco-Bloom E.M., Carpenter E.M., Rodriguez W.I. Neural tube expression of pituitary adenylate cyclase-activating peptide (PACAP) and receptor: potential role in patterning and neurogenesis. Proc. Natl. Acad. Sci. U.S.A. 95:1998;9602-9607.