The Dlk1 and Gtl2 genes are linked and reciprocally imprinted

Genes and Development

Volumn 14, Issue 16, 2000, Pages 1997-2002

  Schmidt, Jennifer V ^a,b   Matteson, Paul G ^a   Jones, Beverly K ^a   Guan, Xiao Juan ^a   Tilghman, Shirley M ^a  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Dlk1; Genomic imprinting; Gtl2

Indexed keywords

CELL DNA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRICETIDAE; DNA METHYLATION; EMBRYO; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE LOCATION; GENE MAPPING; GENE SEQUENCE; GENETIC LINKAGE; GENOME IMPRINTING; HUMAN; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 0034663920     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.14.16.1997     Document Type: Article

References (34)

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3. Competition - A common motif for the imprinting mechanism?
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6. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
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14. CTCF mediates methylation-sensitive enhancer blocking activity at the H19/Igf2 locus
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19. An enhancer deletion affects both H19 and Igf2 expression
20. The role of DNA methylation in genomic imprinting
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25. Gtl2lacZ, an insertional mutation on mouse chromosome 12 with parental origin-dependent phenotype
26. Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern
27. Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation
28. Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation
29. Maternal uniparental disomy for chromosome 14
30. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
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34. Imprinted expression of the Igf2r gene depends on an intronic CpG island