-
1
-
-
0038452658
-
Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity
-
Abramov AY, Canevari L, Duchen MR (2003) Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity. J Neurosci 23:5088-5095 (Pubitemid 36793236)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.12
, pp. 5088-5095
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
2
-
-
84866148510
-
Calcium signaling and gliotransmission in normal vs. reactive astrocytes
-
Agulhon C, Sun MY, Murphy T, Myers T, Lauderdale K, Fiacco TA (2012) Calcium signaling and gliotransmission in normal vs. reactive astrocytes. Front Pharmacol 3:139
-
(2012)
Front Pharmacol
, vol.3
, pp. 139
-
-
Agulhon, C.1
Sun, M.Y.2
Murphy, T.3
Myers, T.4
Lauderdale, K.5
Fiacco, T.A.6
-
3
-
-
0035487313
-
Cytokines and acute neurodegeneration
-
DOI 10.1038/35094583
-
Allan SM, Rothwell NJ (2001) Cytokines and acute neurodegeneration. Nat Rev Neurosci 2:734-744 (Pubitemid 33674819)
-
(2001)
Nature Reviews Neuroscience
, vol.2
, Issue.10
, pp. 734-744
-
-
Allan, S.M.1
Rothwell, N.J.2
-
5
-
-
55249116379
-
Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling
-
Avignone E, Ulmann L, Levavasseur F, Rassendren F, Audinat E (2008) Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling. J Neurosci 28:9133-9144
-
(2008)
J Neurosci
, vol.28
, pp. 9133-9144
-
-
Avignone, E.1
Ulmann, L.2
Levavasseur, F.3
Rassendren, F.4
Audinat, E.5
-
6
-
-
75949127404
-
Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders
-
Bernhardi R von, Tichauer JE, Eugenin J (2010) Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders. J Neurochem 112:1099-1114
-
(2010)
J Neurochem
, vol.112
, pp. 1099-1114
-
-
Bernhardi, R.1
Von Tichauer, J.E.2
Eugenin, J.3
-
7
-
-
0038125598
-
Calcium signalling: Dynamics, homeostasis and remodelling
-
DOI 10.1038/nrm1155
-
Berridge MJ, Bootman MD, Roderick HL (2003) Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4:517-529 (Pubitemid 36773404)
-
(2003)
Nature Reviews Molecular Cell Biology
, vol.4
, Issue.7
, pp. 517-529
-
-
Berridge, M.J.1
Bootman, M.D.2
Roderick, H.L.3
-
8
-
-
50249135503
-
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
-
Bezprozvanny I, Mattson MP (2008) Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci 31:454-463
-
(2008)
Trends Neurosci
, vol.31
, pp. 454-463
-
-
Bezprozvanny, I.1
Mattson, M.P.2
-
9
-
-
0034960228
-
CXCR4-activated astrocyte glutamate release via TNFa: Amplification by microglia triggers neurotoxicity
-
DOI 10.1038/89490
-
Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E, Vescovi A, Bagetta G, Kollias G, Meldolesi J, Volterra A (2001) CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci 4:702-710 (Pubitemid 32595408)
-
(2001)
Nature Neuroscience
, vol.4
, Issue.7
, pp. 702-710
-
-
Bezzi, P.1
Domercq, M.2
Brambilla, L.3
Galli, R.4
Schols, D.5
De Clercq, E.6
Vescovi, A.7
Bagetta, G.8
Kollias, G.9
Meldolesi, J.10
Volterra, A.11
-
10
-
-
0031717546
-
Increased release of ATP from endothelial cells during acute inflammation
-
DOI 10.1007/s000110050341
-
Bodin P, Burnstock G (1998) Increased release of ATP from endothelial cells during acute inflammation. Inflamm Res 47:351-354 (Pubitemid 28425167)
-
(1998)
Inflammation Research
, vol.47
, Issue.8
, pp. 351-354
-
-
Bodin, P.1
Burnstock, G.2
-
11
-
-
84875272285
-
Microglial calcium signaling in the adult, aged and diseased brain
-
Brawek B, Garaschuk O (2013)Microglial calcium signaling in the adult, aged and diseased brain. Cell Calcium 53:159-169
-
(2013)
Cell Calcium
, vol.53
, pp. 159-169
-
-
Brawek, B.1
Garaschuk, O.2
-
12
-
-
23944444806
-
Molecular, structural, and functional characterization of Alzheimer's disease: Evidence for a relationship between default activity, amyloid, and memory
-
DOI 10.1523/JNEUROSCI.2177-05.2005
-
Buckner RL, Snyder AZ, Shannon BJ, LaRossa G, Sachs R, Fotenos AF, Sheline YI, Klunk WE, Mathis CA, Morris JC, Mintun MA (2005) Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci 25:7709-7717 (Pubitemid 41208641)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.34
, pp. 7709-7717
-
-
Buckner, R.L.1
Snyder, A.Z.2
Shannon, B.J.3
LaRossa, G.4
Sachs, R.5
Fotenos, A.F.6
Sheline, Y.I.7
Klunk, W.E.8
Mathis, C.A.9
Morris, J.C.10
Mintun, M.A.11
-
13
-
-
52249115856
-
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
-
Busche MA, Eichhoff G, Adelsberger H, Abramowski D, Wiederhold KH, Haass C, Staufenbiel M, Konnerth A, Garaschuk O (2008) Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science 321:1686-1689
-
(2008)
Science
, vol.321
, pp. 1686-1689
-
-
Busche, M.A.1
Eichhoff, G.2
Adelsberger, H.3
Abramowski, D.4
Wiederhold, K.H.5
Haass, C.6
Staufenbiel, M.7
Konnerth, A.8
Garaschuk, O.9
-
14
-
-
84861844315
-
Critical role of soluble amyloidbeta for early hippocampal hyperactivity in a mouse model of Alzheimer 's disease
-
Busche MA, Chen X, Henning HA, Reichwald J, Staufenbiel M, Sakmann B, Konnerth A (2012) Critical role of soluble amyloidbeta for early hippocampal hyperactivity in a mouse model of Alzheimer 's disease. Proc Natl Acad Sci U S A 109:8740-8745
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 8740-8745
-
-
Busche, M.A.1
Chen, X.2
Henning, H.A.3
Reichwald, J.4
Staufenbiel, M.5
Sakmann, B.6
Konnerth, A.7
-
15
-
-
84861743669
-
Oligomers of beta-amyloid protein (Abeta1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1beta, tumour necrosis factoralpha, and a nuclear factor kappa-B mechanism in the rat brain
-
Carrero I, Gonzalo MR, Martin B, Sanz-Anquela JM, Arevalo-Serrano J, Gonzalo-Ruiz A (2012) Oligomers of beta-amyloid protein (Abeta1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1beta, tumour necrosis factoralpha, and a nuclear factor kappa-B mechanism in the rat brain. Exp Neurol 236:215-227
-
(2012)
Exp Neurol
, vol.236
, pp. 215-227
-
-
Carrero, I.1
Gonzalo, M.R.2
Martin, B.3
Sanz-Anquela, J.M.4
Arevalo-Serrano, J.5
Gonzalo-Ruiz, A.6
-
16
-
-
84871355082
-
2+ channel function as an early preventative strategy for Alzheimer's disease
-
2+ channel function as an early preventative strategy for Alzheimer's disease. PLoS One 7:e52056
-
(2012)
PLoS One
, vol.7
-
-
Chakroborty, S.1
Briggs, C.2
Miller, M.B.3
Goussakov, I.4
Schneider, C.5
Kim, J.6
Wicks, J.7
Richardson, J.C.8
Conklin, V.9
Cameransi, B.G.10
Stutzmann, G.E.11
-
17
-
-
84862261275
-
Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer 's disease mice
-
Chakroborty S, Kim J, Schneider C, Jacobson C, Molgo J, Stutzmann GE (2012b) Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer 's disease mice. J Neurosci 32:8341-8353
-
(2012)
J Neurosci
, vol.32
, pp. 8341-8353
-
-
Chakroborty, S.1
Kim, J.2
Schneider, C.3
Jacobson, C.4
Molgo, J.5
Stutzmann, G.E.6
-
18
-
-
45249117227
-
3 receptor channel gating
-
3 receptor channel gating. Neuron 58:871-883
-
(2008)
Neuron
, vol.58
, pp. 871-883
-
-
Cheung, K.H.1
Shineman, D.2
Muller, M.3
Cardenas, C.4
Mei, L.5
Yang, J.6
Tomita, T.7
Iwatsubo, T.8
Lee, V.M.9
Foskett, J.K.10
-
19
-
-
29144487182
-
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo
-
DOI 10.1016/j.neuron.2005.10.028, PII S0896627305009396
-
Cirrito JR, Yamada KA, Finn MB, Sloviter RS, Bales KR, May PC, Schoepp DD, Paul SM, Mennerick S, Holtzman DM (2005) Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. Neuron 48:913-922 (Pubitemid 41814696)
-
(2005)
Neuron
, vol.48
, Issue.6
, pp. 913-922
-
-
Cirrito, J.R.1
Yamada, K.A.2
Finn, M.B.3
Sloviter, R.S.4
Bales, K.R.5
May, P.C.6
Schoepp, D.D.7
Paul, S.M.8
Mennerick, S.9
Holtzman, D.M.10
-
20
-
-
41549155927
-
Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-beta In Vivo
-
DOI 10.1016/j.neuron.2008.02.003, PII S0896627308001244
-
Cirrito JR, Kang JE, Lee J, Stewart FR, Verges DK, Silverio LM, Bu G, Mennerick S, Holtzman DM (2008) Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo. Neuron 58:42-51 (Pubitemid 351467029)
-
(2008)
Neuron
, vol.58
, Issue.1
, pp. 42-51
-
-
Cirrito, J.R.1
Kang, J.-E.2
Lee, J.3
Stewart, F.R.4
Verges, D.K.5
Silverio, L.M.6
Bu, G.7
Mennerick, S.8
Holtzman, D.M.9
-
21
-
-
22244464662
-
ATP mediates rapid microglial response to local brain injury in vivo
-
DOI 10.1038/nn1472, PII NN1472
-
Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, Littman DR, Dustin ML, Gan WB (2005) ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci 8:752-758 (Pubitemid 43085841)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.6
, pp. 752-758
-
-
Davalos, D.1
Grutzendler, J.2
Yang, G.3
Kim, J.V.4
Zuo, Y.5
Jung, S.6
Littman, D.R.7
Dustin, M.L.8
Gan, W.-B.9
-
22
-
-
34249672242
-
Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
-
DOI 10.1074/jbc.M607483200
-
De Felice FG, Velasco PT, Lambert MP, Viola K, Fernandez SJ, Ferreira ST, Klein WL (2007) Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drugmemantine. J Biol Chem 282:11590-11601 (Pubitemid 47100810)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.15
, pp. 11590-11601
-
-
De Felice, F.G.1
Velasco, P.T.2
Lambert, M.P.3
Viola, K.4
Fernandez, S.J.5
Ferreira, S.T.6
Klein, W.L.7
-
23
-
-
84874590326
-
2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate
-
2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate. J Neurosci 33:3824-3833
-
(2013)
J Neurosci
, vol.33
, pp. 3824-3833
-
-
Demuro, A.1
Parker, I.2
-
24
-
-
20444496481
-
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
-
DOI 10.1074/jbc.M500997200
-
Demuro A, Mina E, Kayed R, Milton SC, Parker I, Glabe CG (2005) Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J Biol Chem 280:17294-17300 (Pubitemid 41389198)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 17294-17300
-
-
Demuro, A.1
Mina, E.2
Kayed, R.3
Milton, S.C.4
Parker, I.5
Glabe, C.G.6
-
26
-
-
34547653708
-
Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice
-
DOI 10.1016/j.nlm.2007.03.010, PII S1074742707000494
-
Dineley KT, Hogan D, Zhang WR, Taglialatela G (2007) Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice. Neurobiol Learn Mem 88:217-224 (Pubitemid 47223751)
-
(2007)
Neurobiology of Learning and Memory
, vol.88
, Issue.2
, pp. 217-224
-
-
Dineley, K.T.1
Hogan, D.2
Zhang, W.-R.3
Taglialatela, G.4
-
27
-
-
33750052586
-
P2Y1 receptor-evoked glutamate exocytosis from astrocytes: Control by tumor necrosis factor-alpha and prostaglandins
-
DOI 10.1074/jbc.M606429200
-
Domercq M, Brambilla L, Pilati E, Marchaland J, Volterra A, Bezzi P (2006) P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandins. J Biol Chem 281:30684-30696 (Pubitemid 44582124)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.41
, pp. 30684-30696
-
-
Domercq, M.1
Brambilla, L.2
Pilati, E.3
Marchaland, J.4
Volterra, A.5
Bezzi, P.6
-
28
-
-
79955661936
-
Microglial calcium signal acts as a rapid sensor of single neuron damage in vivo
-
Eichhoff G, Brawek B, Garaschuk O (2011) Microglial calcium signal acts as a rapid sensor of single neuron damage in vivo. Biochim Biophys Acta 1813:1014-1024
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1014-1024
-
-
Eichhoff, G.1
Brawek, B.2
Garaschuk, O.3
-
29
-
-
0036850023
-
Neuroinflammation in Alzheimer's disease and prion disease
-
DOI 10.1002/glia.10146
-
Eikelenboom P, Bate C, Van Gool WA, Hoozemans JJ, Rozemuller JM, Veerhuis R, Williams A (2002) Neuroinflammation in Alzheimer's disease and prion disease. Glia 40:232-239 (Pubitemid 35337380)
-
(2002)
GLIA
, vol.40
, Issue.2
, pp. 232-239
-
-
Eikelenboom, P.1
Bate, C.2
Van Gool, W.A.3
Hoozemans, J.J.M.4
Rozemuller, J.M.5
Veerhuis, R.6
Williams, A.7
-
30
-
-
33750305578
-
Functional role of calcium signals for microglial function
-
DOI 10.1002/glia.20412
-
Färber K, Kettenmann H (2006) Functional role of calcium signals for microglial function. Glia 54:656-665 (Pubitemid 44629629)
-
(2006)
GLIA
, vol.54
, Issue.7
, pp. 656-665
-
-
Farber, K.1
Kettenmann, H.2
-
31
-
-
60749104683
-
The inflammasome: A caspase-1-activation platform that regulates immune responses and disease pathogenesis
-
Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G (2009) The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 10:241-247
-
(2009)
Nat Immunol
, vol.10
, pp. 241-247
-
-
Franchi, L.1
Eigenbrod, T.2
Munoz-Planillo, R.3
Nunez, G.4
-
33
-
-
84860304777
-
Staged decline of neuronal function in vivo in an animal model of Alzheimer's disease
-
Grienberger C, Rochefort NL, Adelsberger H, Henning HA, Hill DN, Reichwald J, Staufenbiel M, Konnerth A (2012) Staged decline of neuronal function in vivo in an animal model of Alzheimer's disease. Nat Commun 3:774
-
(2012)
Nat Commun
, vol.3
, pp. 774
-
-
Grienberger, C.1
Rochefort, N.L.2
Adelsberger, H.3
Henning, H.A.4
Hill, D.N.5
Reichwald, J.6
Staufenbiel, M.7
Konnerth, A.8
-
34
-
-
84879353571
-
Amyloid-beta and Alzheimer 's disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions
-
Grolla AA, Sim JA, Lim D, Rodriguez JJ, Genazzani AA, Verkhratsky A (2013) Amyloid-beta and Alzheimer 's disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions. Cell Death Dis 4:e623
-
(2013)
Cell Death Dis
, vol.4
-
-
Grolla, A.A.1
Sim, J.A.2
Lim, D.3
Rodriguez, J.J.4
Genazzani, A.A.5
Verkhratsky, A.6
-
35
-
-
77951929051
-
Integrated brain circuits: Astrocytic networks modulate neuronal activity and behavior
-
Halassa MM, Haydon PG (2010) Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu Rev Physiol 72:335-355
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 335-355
-
-
Halassa, M.M.1
Haydon, P.G.2
-
36
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT (2008) The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol 9:857-865
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
37
-
-
35548986304
-
Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
-
Hanisch UK, Kettenmann H (2007)Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10: 1387-1394
-
(2007)
Nat Neurosci
, vol.10
, pp. 1387-1394
-
-
Hanisch, U.K.1
Kettenmann, H.2
-
38
-
-
84873087532
-
NLRP3 is activated in Alzheimer 's disease and contributes to pathology in APP/PS1 mice
-
Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT (2013) NLRP3 is activated in Alzheimer 's disease and contributes to pathology in APP/PS1 mice. Nature 493:674-678
-
(2013)
Nature
, vol.493
, pp. 674-678
-
-
Heneka, M.T.1
Kummer, M.P.2
Stutz, A.3
Delekate, A.4
Schwartz, S.5
Vieira-Saecker, A.6
Griep, A.7
Axt, D.8
Remus, A.9
Tzeng, T.C.10
Gelpi, E.11
Halle, A.12
Korte, M.13
Latz, E.14
Golenbock, D.T.15
-
39
-
-
74549135360
-
Long-term potentiation depends on release of D-serine from astrocytes
-
Henneberger C, Papouin T, Oliet SH, Rusakov DA (2010) Long-term potentiation depends on release of D-serine from astrocytes. Nature 463:232-236
-
(2010)
Nature
, vol.463
, pp. 232-236
-
-
Henneberger, C.1
Papouin, T.2
Oliet, S.H.3
Rusakov, D.A.4
-
40
-
-
0033836116
-
Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia
-
DOI 10.1046/j.1471-4159.2000.0750965.x
-
Hide I, Tanaka M, Inoue A, Nakajima K, Kohsaka S, Inoue K, Nakata Y (2000) Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. J Neurochem 75:965-972 (Pubitemid 30660484)
-
(2000)
Journal of Neurochemistry
, vol.75
, Issue.3
, pp. 965-972
-
-
Hide, I.1
Tanaka, M.2
Inoue, A.3
Nakajima, K.4
Kohsaka, S.5
Inoue, K.6
Nakata, Y.7
-
42
-
-
0038795206
-
Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): Suppression of receptor-evoked calcium signaling and control of release function
-
Hoffmann A, Kann O, Ohlemeyer C, Hanisch UK, Kettenmann H (2003) Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function. J Neurosci 23:4410-4419 (Pubitemid 36706171)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.11
, pp. 4410-4419
-
-
Hoffmann, A.1
Kann, O.2
Ohlemeyer, C.3
Hanisch, U.-K.4
Kettenmann, H.5
-
43
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
DOI 10.1126/science.274.5284.99
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99-102 (Pubitemid 26332733)
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
44
-
-
84881085639
-
2+ channels mediates TNF-alpha release from microglial cells under chronic purinergic stimulation
-
2+ channels mediates TNF-alpha release from microglial cells under chronic purinergic stimulation. Biochim Biophys Acta 1833:2573-2585
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 2573-2585
-
-
Ikeda, M.1
Tsuno, S.2
Sugiyama, T.3
Hashimoto, A.4
Yamoto, K.5
Takeuchi, K.6
Kishi, H.7
Mizuguchi, H.8
Kohsaka, S.I.9
Yoshioka, T.10
-
45
-
-
84880699775
-
Microglia release ATP by exocytosis
-
Imura Y, Morizawa Y, Komatsu R, Shibata K, Shinozaki Y, Kasai H, Moriishi K, Moriyama Y, Koizumi S (2013) Microglia release ATP by exocytosis. Glia 61:1320-1330
-
(2013)
Glia
, vol.61
, pp. 1320-1330
-
-
Imura, Y.1
Morizawa, Y.2
Komatsu, R.3
Shibata, K.4
Shinozaki, Y.5
Kasai, H.6
Moriishi, K.7
Moriyama, Y.8
Koizumi, S.9
-
46
-
-
0024436506
-
Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease
-
DOI 10.1016/0165-5728(89)90115-X
-
Itagaki S, McGeer PL, Akiyama H, Zhu S, Selkoe D (1989) Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease. J Neuroimmunol 24:173-182 (Pubitemid 19271472)
-
(1989)
Journal of Neuroimmunology
, vol.24
, Issue.3
, pp. 173-182
-
-
Itagaki, S.1
McGeer, P.L.2
Akiyama, H.3
Zhu, S.4
Selkoe, D.5
-
47
-
-
0028179578
-
2+ mobilization is altered in fibroblasts from patients with Alzheimer disease
-
2+ mobilization is altered in fibroblasts from patients with Alzheimer disease. Proc Natl Acad Sci U S A 91:534-538
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 534-538
-
-
Ito, E.1
Oka, K.2
Etcheberrigaray, R.3
Nelson, T.J.4
McPhie, D.L.5
Tofel-Grehl, B.6
Gibson, G.E.7
Alkon, D.L.8
-
48
-
-
0344672942
-
APP Processing and Synaptic Function
-
DOI 10.1016/S0896-6273(03)00124-7
-
Kamenetz F, Tomita T, Hsieh H, Seabrook G, Borchelt D, Iwatsubo T, Sisodia S, Malinow R (2003)APP processing and synaptic function. Neuron 37:925-937 (Pubitemid 36398299)
-
(2003)
Neuron
, vol.37
, Issue.6
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrook, G.4
Borchelt, D.5
Iwatsubo, T.6
Sisodia, S.7
Malinow, R.8
-
49
-
-
0028651951
-
Calcium hypothesis of Alzheimer's disease and brain aging
-
Khachaturian ZS (1994) Calcium hypothesis of Alzheimer's disease and brain aging. Ann N YAcad Sci 747:1-11
-
(1994)
Ann N YAcad Sci
, vol.747
, pp. 1-11
-
-
Khachaturian, Z.S.1
-
50
-
-
34247637676
-
6 receptors is a mediator of microglial phagocytosis
-
DOI 10.1038/nature05704, PII NATURE05704
-
Koizumi S, Shigemoto-Mogami Y, Nasu-Tada K, Shinozaki Y, Ohsawa K, Tsuda M, Joshi BV, Jacobson KA, Kohsaka S, Inoue K (2007) UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis. Nature 446:1091-1095 (Pubitemid 46676051)
-
(2007)
Nature
, vol.446
, Issue.7139
, pp. 1091-1095
-
-
Koizumi, S.1
Shigemoto-Mogami, Y.2
Nasu-Tada, K.3
Shinozaki, Y.4
Ohsawa, K.5
Tsuda, M.6
Joshi, B.V.7
Jacobson, K.A.8
Kohsaka, S.9
Inoue, K.10
-
51
-
-
47749113650
-
Abeta Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks
-
DOI 10.1016/j.neuron.2008.06.008, PII S0896627308005011
-
Kuchibhotla KV, Goldman ST, Lattarulo CR, Wu HY, Hyman BT, Bacskai BJ (2008) Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks. Neuron 59:214-225 (Pubitemid 352033686)
-
(2008)
Neuron
, vol.59
, Issue.2
, pp. 214-225
-
-
Kuchibhotla, K.V.1
Goldman, S.T.2
Lattarulo, C.R.3
Wu, H.-Y.4
Hyman, B.T.5
Bacskai, B.J.6
-
52
-
-
61349096009
-
Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
-
Kuchibhotla KV, Lattarulo CR, Hyman BT, Bacskai BJ (2009) Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 323:1211-1215
-
(2009)
Science
, vol.323
, pp. 1211-1215
-
-
Kuchibhotla, K.V.1
Lattarulo, C.R.2
Hyman, B.T.3
Bacskai, B.J.4
-
53
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla FM (2002) Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci 3:862-872
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 862-872
-
-
LaFerla, F.M.1
-
54
-
-
84870508924
-
2+ and cAMP
-
2+ and cAMP. Nature 492:123-127
-
(2012)
Nature
, vol.492
, pp. 123-127
-
-
Lee, G.S.1
Subramanian, N.2
Kim, A.I.3
Aksentijevich, I.4
Goldbach-Mansky, R.5
Sacks, D.B.6
Germain, R.N.7
Kastner, D.L.8
Chae, J.J.9
-
55
-
-
78349279184
-
Astrocytes are GABAergic cells that modulate microglial activity
-
Lee M, Schwab C, McGeer PL (2011) Astrocytes are GABAergic cells that modulate microglial activity. Glia 59:152-165
-
(2011)
Glia
, vol.59
, pp. 152-165
-
-
Lee, M.1
Schwab, C.2
McGeer, P.L.3
-
56
-
-
84879605797
-
Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB
-
Lim D, Iyer A, Ronco V, Grolla AA, Canonico PL, Aronica E, Genazzani AA (2013) Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB. Glia 61:1134-1145
-
(2013)
Glia
, vol.61
, pp. 1134-1145
-
-
Lim, D.1
Iyer, A.2
Ronco, V.3
Grolla, A.A.4
Canonico, P.L.5
Aronica, E.6
Genazzani, A.A.7
-
57
-
-
84873407062
-
Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen
-
Mathiesen C, Brazhe A, Thomsen K, Lauritzen M (2013) Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen. J Cereb Blood Flow Metab 33:161-169
-
(2013)
J Cereb Blood Flow Metab
, vol.33
, pp. 161-169
-
-
Mathiesen, C.1
Brazhe, A.2
Thomsen, K.3
Lauritzen, M.4
-
58
-
-
77953634580
-
ER calcium and Alzheimer's disease: In a state of flux
-
Mattson MP (2010) ER calcium and Alzheimer's disease: in a state of flux. Sci Signal 3:pe10
-
(2010)
Sci Signal
, vol.3
-
-
Mattson, M.P.1
-
59
-
-
0042536471
-
Neuronal and glial calcium signaling in Alzheimer's disease
-
DOI 10.1016/S0143-4160(03)00128-3
-
Mattson MP, Chan SL (2003) Neuronal and glial calcium signaling in Alzheimer 's disease. Cell Calcium 34:385-397 (Pubitemid 37021231)
-
(2003)
Cell Calcium
, vol.34
, Issue.4-5
, pp. 385-397
-
-
Mattson, M.P.1
Chan, S.L.2
-
60
-
-
84885456046
-
The amyloid cascade-inflammatory hypothesis of Alzheimer disease: Implications for therapy
-
McGeer PL, McGeer EG (2013) The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy. Acta Neuropathol 126:479-497
-
(2013)
Acta Neuropathol
, vol.126
, pp. 479-497
-
-
McGeer, P.L.1
McGeer, E.G.2
-
61
-
-
25444473871
-
Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients
-
DOI 10.1002/jnr.20487
-
McLarnon JG, Choi HB, Lue LF, Walker DG, Kim SU (2005) Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients. J Neurosci Res 81:426-435 (Pubitemid 41359297)
-
(2005)
Journal of Neuroscience Research
, vol.81
, Issue.3
, pp. 426-435
-
-
McLarnon, J.G.1
Choi, H.B.2
Lue, L.-F.3
Walker, D.G.4
Kim, S.U.5
-
62
-
-
33750601018
-
Upregulated expression of purinergic P2X7 receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus
-
DOI 10.1097/01.jnen.0000240470.97295.d3, PII 0000507220061100000008
-
McLarnon JG, Ryu JK, Walker DG, Choi HB (2006) Upregulated expression of purinergic P2X7 receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus. J Neuropathol Exp Neurol 65:1090-1097 (Pubitemid 44684667)
-
(2006)
Journal of Neuropathology and Experimental Neurology
, vol.65
, Issue.11
, pp. 1090-1097
-
-
McLarnon, J.G.1
Ryu, J.K.2
Walker, D.G.3
Choi, H.B.4
-
63
-
-
84868252916
-
Astrocytes: Conductors of the Alzheimer disease neuroinflammatory symphony
-
Medeiros R, LaFerla FM (2013) Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony. Exp Neurol 239:133-138
-
(2013)
Exp Neurol
, vol.239
, pp. 133-138
-
-
Medeiros, R.1
LaFerla, F.M.2
-
64
-
-
0141761520
-
Seizures in elderly patients with dementia: Epidemiology and management
-
DOI 10.2165/00002512-200320110-00001
-
Mendez M, Lim G (2003) Seizures in elderly patients with dementia: epidemiology and management. Drugs Aging 20:791-803 (Pubitemid 37159597)
-
(2003)
Drugs and Aging
, vol.20
, Issue.11
, pp. 791-803
-
-
Mendez, M.F.1
Lim, G.T.H.2
-
65
-
-
84882665749
-
Inflammatory process in Alzheimer's Disease
-
Meraz-Rios MA, Toral-Rios D, Franco-Bocanegra D, Villeda-Hernandez J, Campos-Pena V (2013) Inflammatory process in Alzheimer's Disease. Front Integr Neurosci 7:59
-
(2013)
Front Integr Neurosci
, vol.7
, pp. 59
-
-
Meraz-Rios, M.A.1
Toral-Rios, D.2
Franco-Bocanegra, D.3
Villeda-Hernandez, J.4
Campos-Pena, V.5
-
66
-
-
38949123792
-
Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease
-
DOI 10.1038/nature06616, PII NATURE06616
-
Meyer-Luehmann M, Spires-Jones TL, Prada C, Garcia-Alloza M, Calignon A de, Rozkalne A, Koenigsknecht-Talboo J, Holtzman DM, Bacskai BJ, Hyman BT (2008) Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease. Nature 451:720-724 (Pubitemid 351220570)
-
(2008)
Nature
, vol.451
, Issue.7179
, pp. 720-724
-
-
Meyer-Luehmann, M.1
Spires-Jones, T.L.2
Prada, C.3
Garcia-Alloza, M.4
De Calignon, A.5
Rozkalne, A.6
Koenigsknecht-Talboo, J.7
Holtzman, D.M.8
Bacskai, B.J.9
Hyman, B.T.10
-
67
-
-
42649097901
-
The effects of aging, injury and disease on microglial function: A case for cellular senescence
-
DOI 10.1017/S1740925X08000136, PII S1740925X08000136
-
Miller KR, Streit WJ (2007) The effects of aging, injury and disease on microglial function: a case for cellular senescence. Neuron Glia Biol 3:245-253 (Pubitemid 351594233)
-
(2007)
Neuron Glia Biology
, vol.3
, Issue.3
, pp. 245-253
-
-
Miller, K.R.1
Streit, W.J.2
-
68
-
-
84860274847
-
Astrocyte signaling controls spike timing-dependent depression at neocortical synapses
-
Min R, Nevian T (2012) Astrocyte signaling controls spike timing-dependent depression at neocortical synapses. Nat Neurosci 15:746-753
-
(2012)
Nat Neurosci
, vol.15
, pp. 746-753
-
-
Min, R.1
Nevian, T.2
-
69
-
-
84868108811
-
The computational power of astrocyte mediated synaptic plasticity
-
Min R, Santello M, Nevian T (2012) The computational power of astrocyte mediated synaptic plasticity. Front Comput Neurosci 6:93
-
(2012)
Front Comput Neurosci
, vol.6
, pp. 93
-
-
Min, R.1
Santello, M.2
Nevian, T.3
-
70
-
-
0036847845
-
Calcium signaling in microglial cells
-
Möller T (2002) Calcium signaling in microglial cells. Glia 40:184-194
-
(2002)
Glia
, vol.40
, pp. 184-194
-
-
Möller, T.1
-
72
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami T, Ockinger J, Yu J, Byles V, McColl A, Hofer AM, Horng T (2012) Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc Natl Acad Sci U S A 109:11282-11287
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
Horng, T.7
-
73
-
-
77957299242
-
Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes
-
Navarrete M, Araque A (2010) Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes. Neuron 68:113-126
-
(2010)
Neuron
, vol.68
, pp. 113-126
-
-
Navarrete, M.1
Araque, A.2
-
74
-
-
65249181309
-
Astrocytes going live: Advances and challenges
-
Nimmerjahn A (2009) Astrocytes going live: advances and challenges. J Physiol (Lond) 587:1639-1647
-
(2009)
J Physiol (Lond)
, vol.587
, pp. 1639-1647
-
-
Nimmerjahn, A.1
-
75
-
-
19744380563
-
Neuroscience: Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
DOI 10.1126/science.1110647
-
Nimmerjahn A, Kirchhoff F, Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308:1314-1318 (Pubitemid 40746128)
-
(2005)
Science
, vol.308
, Issue.5726
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
76
-
-
0042697305
-
Triple-transgenic model of Alzheimer's Disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
DOI 10.1016/S0896-6273(03)00434-3
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM (2003) Triple-transgenic model of Alzheimer 's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39:409-421 (Pubitemid 36937044)
-
(2003)
Neuron
, vol.39
, Issue.3
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
77
-
-
18144394715
-
2+-permeable alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate (AMPA)/kainate (Ca-A/K) channels in a subset of hippocampal pyramidal neurons
-
2+-permeable alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate (AMPA)/kainate (Ca-A/K) channels in a subset of hippocampal pyramidal neurons. Exp Neurol 193:384-393
-
(2005)
Exp Neurol
, vol.193
, pp. 384-393
-
-
Ogoshi, F.1
Yin, H.Z.2
Kuppumbatti, Y.3
Song, B.4
Amindari, S.5
Weiss, J.H.6
-
78
-
-
84865254936
-
Ryanodine receptor blockade reduces amyloid-beta load and memory impairments in Tg2576 mouse model of Alzheimer disease
-
Oules B, Del Prete D, Greco B, Zhang X, Lauritzen I, Sevalle J, Moreno S, Paterlini-Brechot P, Trebak M, Checler F, Benfenati F, Chami M (2012) Ryanodine receptor blockade reduces amyloid-beta load and memory impairments in Tg2576 mouse model of Alzheimer disease. J Neurosci 32:11820-11834
-
(2012)
J Neurosci
, vol.32
, pp. 11820-11834
-
-
Oules, B.1
Del Prete, D.2
Greco, B.3
Zhang, X.4
Lauritzen, I.5
Sevalle, J.6
Moreno, S.7
Paterlini-Brechot, P.8
Trebak, M.9
Checler, F.10
Benfenati, F.11
Chami, M.12
-
79
-
-
65249091454
-
Epilepsy and cognitive impairments in Alzheimer disease
-
Palop JJ, Mucke L (2009) Epilepsy and cognitive impairments in Alzheimer disease. Arch Neurol 66:435-440
-
(2009)
Arch Neurol
, vol.66
, pp. 435-440
-
-
Palop, J.J.1
Mucke, L.2
-
80
-
-
77954132249
-
Amyloid-beta-induced neuronal dysfunction in Alzheimer 's disease: From synapses toward neural networks
-
Palop JJ, Mucke L (2010) Amyloid-beta-induced neuronal dysfunction in Alzheimer 's disease: from synapses toward neural networks. Nat Neurosci 13:812-818
-
(2010)
Nat Neurosci
, vol.13
, pp. 812-818
-
-
Palop, J.J.1
Mucke, L.2
-
81
-
-
80052633284
-
Synaptic pruning by microglia is necessary for normal brain development
-
Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, Giustetto M, Ferreira TA, Guiducci E, Dumas L, Ragozzino D, Gross CT (2011) Synaptic pruning by microglia is necessary for normal brain development. Science 333:1456-1458
-
(2011)
Science
, vol.333
, pp. 1456-1458
-
-
Paolicelli, R.C.1
Bolasco, G.2
Pagani, F.3
Maggi, L.4
Scianni, M.5
Panzanelli, P.6
Giustetto, M.7
Ferreira, T.A.8
Guiducci, E.9
Dumas, L.10
Ragozzino, D.11
Gross, C.T.12
-
82
-
-
84858704600
-
Glial cells in (patho)physiology
-
Parpura V, Heneka MT, Montana V, Oliet SH, Schousboe A, Haydon PG, Stout RF Jr, Spray DC, Reichenbach A, Pannicke T, Pekny M, Pekna M, Zorec R, Verkhratsky A (2012) Glial cells in (patho)physiology. J Neurochem 121:4-27
-
(2012)
J Neurochem
, vol.121
, pp. 4-27
-
-
Parpura, V.1
Heneka, M.T.2
Montana, V.3
Oliet, S.H.4
Schousboe, A.5
Haydon, P.G.6
Stout Jr., R.F.7
Spray, D.C.8
Reichenbach, A.9
Pannicke, T.10
Pekny, M.11
Pekna, M.12
Zorec, R.13
Verkhratsky, A.14
-
83
-
-
0038143359
-
7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
-
DOI 10.1074/jbc.M209478200
-
Parvathenani LK, Tertyshnikova S, Greco CR, Roberts SB, Robertson B, Posmantur R (2003) P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer 's disease. J Biol Chem 278:13309-13317 (Pubitemid 36800102)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.15
, pp. 13309-13317
-
-
Parvathenani, L.K.1
Tertyshnikova, S.2
Greco, C.R.3
Roberts, S.B.4
Robertson, B.5
Posmantur, R.6
-
84
-
-
84856384517
-
Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission
-
Pascual O, Ben Achour S, Rostaing P, Triller A, Bessis A (2012) Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission. Proc Natl Acad Sci U S A 109:E197-E205
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
-
-
Pascual, O.1
Ben Achour, S.2
Rostaing, P.3
Triller, A.4
Bessis, A.5
-
85
-
-
84860439512
-
Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice
-
Peng J, Liang G, Inan S, Wu Z, Joseph DJ, Meng Q, Peng Y, Eckenhoff MF, Wei H (2012) Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice. Neurosci Lett 516:274-279
-
(2012)
Neurosci Lett
, vol.516
, pp. 274-279
-
-
Peng, J.1
Liang, G.2
Inan, S.3
Wu, Z.4
Joseph, D.J.5
Meng, Q.6
Peng, Y.7
Eckenhoff, M.F.8
Wei, H.9
-
87
-
-
67650844275
-
Epidemiology of Alzheimer's disease: Occurrence, determinants, and strategies toward intervention
-
Qiu C, Kivipelto M, Strauss E von (2009) Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. Dialogues Clin Neurosci 11:111-128
-
(2009)
Dialogues Clin Neurosci
, vol.11
, pp. 111-128
-
-
Qiu, C.1
Kivipelto, M.2
Von Strauss, E.3
-
88
-
-
0028204224
-
Calcium ionophore increases amyloid beta peptide production by cultured cells
-
Querfurth HW, Selkoe DJ (1994) Calcium ionophore increases amyloid beta peptide production by cultured cells. Biochemistry 33:4550-4561 (Pubitemid 24145103)
-
(1994)
Biochemistry
, vol.33
, Issue.15
, pp. 4550-4561
-
-
Querfurth, H.W.1
Selkoe, D.J.2
-
89
-
-
0030987603
-
Caffeine stimulates amyloid beta-peptide release from beta-amyloid precursor protein-transfected HEK293 cells
-
Querfurth HW, Jiang J, Geiger JD, Selkoe DJ (1997) Caffeine stimulates amyloid beta-peptide release from beta-amyloid precursor protein-transfected HEK293 cells. J Neurochem 69:1580-1591 (Pubitemid 27406959)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.4
, pp. 1580-1591
-
-
Querfurth, H.W.1
Jiang, J.2
Geiger, J.D.3
Selkoe, D.J.4
-
90
-
-
55949107105
-
Microglial activation and TNFalpha production mediate altered CNS excitability following peripheral inflammation
-
Riazi K, Galic MA, Kuzmiski JB, Ho W, Sharkey KA, Pittman QJ (2008) Microglial activation and TNFalpha production mediate altered CNS excitability following peripheral inflammation. Proc Natl Acad Sci U S A 105:17151-17156
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17151-17156
-
-
Riazi, K.1
Galic, M.A.2
Kuzmiski, J.B.3
Ho, W.4
Sharkey, K.A.5
Pittman, Q.J.6
-
91
-
-
0028875687
-
Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer 's disease
-
Rockenstein EM, McConlogue L, Tan H, Power M, Masliah E, Mucke L (1995) Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer 's disease. J Biol Chem 270:28257-28267
-
(1995)
J Biol Chem
, vol.270
, pp. 28257-28267
-
-
Rockenstein, E.M.1
McConlogue, L.2
Tan, H.3
Power, M.4
Masliah, E.5
Mucke, L.6
-
92
-
-
71549171171
-
The cortical innate immune response increases local neuronal excitability leading to seizures
-
Rodgers KM, Hutchinson MR, Northcutt A, Maier SF, Watkins LR, Barth DS (2009) The cortical innate immune response increases local neuronal excitability leading to seizures. Brain 132:2478-2486
-
(2009)
Brain
, vol.132
, pp. 2478-2486
-
-
Rodgers, K.M.1
Hutchinson, M.R.2
Northcutt, A.3
Maier, S.F.4
Watkins, L.R.5
Barth, D.S.6
-
93
-
-
29644434681
-
Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease
-
DOI 10.1074/jbc.M504124200
-
Rossi D, Brambilla L, Valori CF, Crugnola A, Giaccone G, Capobianco R, Mangieri M, Kingston AE, Bloc A, Bezzi P, Volterra A (2005) Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease. J Biol Chem 280:42088-42096 (Pubitemid 43023177)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.51
, pp. 42088-42096
-
-
Rossi, D.1
Brambilla, L.2
Valori, C.F.3
Crugnola, A.4
Giaccone, G.5
Capobianco, R.6
Mangieri, M.7
Kingston, A.E.8
Bloc, A.9
Bezzi, P.10
Volterra, A.11
-
94
-
-
84861078831
-
A review: Inflammatory process in Alzheimer 's disease, role of cytokines
-
Rubio-Perez JM, Morillas-Ruiz JM (2012) A review: inflammatory process in Alzheimer 's disease, role of cytokines. Sci World J 2012: 756357
-
(2012)
Sci World J
, vol.2012
, pp. 756357
-
-
Rubio-Perez, J.M.1
Morillas-Ruiz, J.M.2
-
95
-
-
84888205087
-
Calcium dysregulation and neuroinflammation: Discrete and integrated mechanisms for age-related synaptic dysfunction
-
Sama DM, Norris CM (2013) Calcium dysregulation and neuroinflammation: discrete and integrated mechanisms for age-related synaptic dysfunction. Ageing Res Rev 12:982-995
-
(2013)
Ageing Res Rev
, vol.12
, pp. 982-995
-
-
Sama, D.M.1
Norris, C.M.2
-
96
-
-
84867645474
-
Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model
-
Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu GQ, Palop JJ, Mucke L (2012) Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proc Natl Acad Sci U S A 109:E2895-E2903
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
-
-
Sanchez, P.E.1
Zhu, L.2
Verret, L.3
Vossel, K.A.4
Orr, A.G.5
Cirrito, J.R.6
Devidze, N.7
Ho, K.8
Yu, G.Q.9
Palop, J.J.10
Mucke, L.11
-
97
-
-
84866751526
-
TNFalpha in synaptic function: Switching gears
-
Santello M, Volterra A (2012) TNFalpha in synaptic function: switching gears. Trends Neurosci 35:638-647
-
(2012)
Trends Neurosci
, vol.35
, pp. 638-647
-
-
Santello, M.1
Volterra, A.2
-
98
-
-
0035853828
-
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation
-
Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E, Moechars D, Van Leuven F, Herms J (2001) Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. J Biol Chem 276:11539-11544
-
(2001)
J Biol Chem
, vol.276
, pp. 11539-11544
-
-
Schneider, I.1
Reverse, D.2
Dewachter, I.3
Ris, L.4
Caluwaerts, N.5
Kuiperi, C.6
Gilis, M.7
Geerts, H.8
Kretzschmar, H.9
Godaux, E.10
Moechars, D.11
Van Leuven, F.12
Herms, J.13
-
99
-
-
84864754077
-
High resolution in vivo imaging of microglia using a versatile nongeneticallyencoded marker
-
Schwendele B, Brawek B, Hermes M, Garaschuk O (2012) High resolution in vivo imaging of microglia using a versatile nongeneticallyencoded marker. Eur J Immunol 42:2193-2196
-
(2012)
Eur J Immunol
, vol.42
, pp. 2193-2196
-
-
Schwendele, B.1
Brawek, B.2
Hermes, M.3
Garaschuk, O.4
-
102
-
-
28944432753
-
Novel presenilin 1 mutation (S170F) causing Alzheimer disease with lewy bodies in the third decade of life
-
DOI 10.1001/archneur.62.12.1821
-
Snider BJ, Norton J, Coats MA, Chakraverty S, Hou CE, Jervis R, Lendon CL, Goate AM, McKeel DW Jr, Morris JC (2005) Novel presenilin 1mutation (S170F) causing Alzheimer diseasewith Lewy bodies in the third decade of life. Arch Neurol 62:1821-1830 (Pubitemid 41785075)
-
(2005)
Archives of Neurology
, vol.62
, Issue.12
, pp. 1821-1830
-
-
Snider, B.J.1
Norton, J.2
Coats, M.A.3
Chakraverty, S.4
Hou, C.E.5
Jervis, R.6
Lendon, C.L.7
Goate, A.M.8
McKeel Jr., D.W.9
Morris, J.C.10
-
103
-
-
67650875899
-
Amyloid deposition is associated with impaired default network function in older persons without dementia
-
Sperling RA, Laviolette PS, O ' Keefe K, O' Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA (2009) Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 63:178-188
-
(2009)
Neuron
, vol.63
, pp. 178-188
-
-
Sperling, R.A.1
Laviolette, P.S.2
'Keefe K, O.3
O'Brien, J.4
Rentz, D.M.5
Pihlajamaki, M.6
Marshall, G.7
Hyman, B.T.8
Selkoe, D.J.9
Hedden, T.10
Buckner, R.L.11
Becker, J.A.12
Johnson, K.A.13
-
104
-
-
15244352734
-
3 signaling, and Alzheimer 's disease
-
3 signaling, and Alzheimer 's disease. Neuroscientist 11:110-115
-
(2005)
Neuroscientist
, vol.11
, pp. 110-115
-
-
Stutzmann, G.E.1
-
105
-
-
1342288871
-
2+ Signals and Altered Membrane Excitability
-
DOI 10.1523/JNEUROSCI.4386-03.2004
-
Stutzmann GE, Caccamo A, LaFerla FM, Parker I (2004) Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer 's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and alteredmembrane excitability. J Neurosci 24:508-513 (Pubitemid 38112383)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.2
, pp. 508-513
-
-
Stutzmann, G.E.1
Caccamo, A.2
LaFerla, F.M.3
Parker, I.4
-
106
-
-
33646945317
-
2+ disruptions in young, adult, and aged Alzheimer's disease mice
-
2+ disruptions in young, adult, and aged Alzheimer's disease mice. J Neurosci 26:5180-5189
-
(2006)
J Neurosci
, vol.26
, pp. 5180-5189
-
-
Stutzmann, G.E.1
Smith, I.2
Caccamo, A.3
Oddo, S.4
Laferla, F.M.5
Parker, I.6
-
107
-
-
34247621471
-
Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models
-
DOI 10.1196/annals.1379.025, Imaging and the Aging Brain
-
Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, Laferla F (2007) Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer 's mouse models. Ann N Y Acad Sci 1097:265-277 (Pubitemid 47084900)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1097
, pp. 265-277
-
-
Stutzmann, G.E.1
Smith, I.2
Caccamo, A.3
Oddo, S.4
Parker, I.5
Laferla, F.6
-
108
-
-
84872165563
-
Glutamate-dependent neuroglial calcium signaling differs between young and adult brain
-
Sun W, McConnell E, Pare JF, Xu Q, Chen M, Peng W, Lovatt D, Han X, Smith Y, Nedergaard M (2013) Glutamate-dependent neuroglial calcium signaling differs between young and adult brain. Science 339:197-200
-
(2013)
Science
, vol.339
, pp. 197-200
-
-
Sun, W.1
McConnell, E.2
Pare, J.F.3
Xu, Q.4
Chen, M.5
Peng, W.6
Lovatt, D.7
Han, X.8
Smith, Y.9
Nedergaard, M.10
-
109
-
-
62649147319
-
Intermediateand long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition
-
Taglialatela G, Hogan D, Zhang WR, Dineley KT (2009) Intermediateand long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition. Behav Brain Res 200:95-99
-
(2009)
Behav Brain Res
, vol.200
, pp. 95-99
-
-
Taglialatela, G.1
Hogan, D.2
Zhang, W.R.3
Dineley, K.T.4
-
110
-
-
34250174806
-
Prion infection correlates with hypersensitivity of P2X7 nucleotide receptor in a mouse microglial cell line
-
DOI 10.1016/j.febslet.2007.05.057, PII S0014579307005935
-
Takenouchi T, Iwamaru Y, Imamura M, Kato N, Sugama S, Fujita M, Hashimoto M, Sato M, Okada H, Yokoyama T, Mohri S, Kitani H (2007) Prion infection correlates with hypersensitivity of P2X7 nucleotide receptor in a mouse microglial cell line. FEBS Lett 581:3019-3026 (Pubitemid 46899044)
-
(2007)
FEBS Letters
, vol.581
, Issue.16
, pp. 3019-3026
-
-
Takenouchi, T.1
Iwamaru, Y.2
Imamura, M.3
Kato, N.4
Sugama, S.5
Fujita, M.6
Hashimoto, M.7
Sato, M.8
Okada, H.9
Yokoyama, T.10
Mohri, S.11
Kitani, H.12
-
112
-
-
62349114041
-
Extracellular ATP in the immune system: More than just a "danger signal"
-
Trautmann A (2009) Extracellular ATP in the immune system: more than just a "danger signal". Sci Signal 2:pe6
-
(2009)
Sci Signal
, vol.2
-
-
Trautmann, A.1
-
113
-
-
78649976052
-
Microglial interactions with synapses are modulated by visual experience
-
Tremblay ME, Lowery RL, Majewska AK (2010)Microglial interactions with synapses are modulated by visual experience. PLoS Biol 8: e1000527
-
(2010)
PLoS Biol
, vol.8
-
-
Tremblay, M.E.1
Lowery, R.L.2
Majewska, A.K.3
-
114
-
-
33748140720
-
2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations
-
2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 126:981-993
-
(2006)
Cell
, vol.126
, pp. 981-993
-
-
Tu, H.1
Nelson, O.2
Bezprozvanny, A.3
Wang, Z.4
Lee, S.F.5
Hao, Y.H.6
Serneels, L.7
De Strooper, B.8
Yu, G.9
Bezprozvanny, I.10
-
115
-
-
0029411573
-
Presenilins and Alzheimer disease
-
Van Broeckhoven C (1995) Presenilins and Alzheimer disease. Nat Genet 11:230-232
-
(1995)
Nat Genet
, vol.11
, pp. 230-232
-
-
Van Broeckhoven, C.1
-
116
-
-
78751703506
-
ATP in neuron-glia bidirectional signalling
-
Verderio C, Matteoli M (2011) ATP in neuron-glia bidirectional signalling. Brain Res Rev 66:106-114
-
(2011)
Brain Res Rev
, vol.66
, pp. 106-114
-
-
Verderio, C.1
Matteoli, M.2
-
117
-
-
77956378268
-
Recent advances in (patho)physiology of astroglia
-
Verkhratsky A, Parpura V (2010) Recent advances in (patho)physiology of astroglia. Acta Pharmacol Sin 31:1044-1054
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 1044-1054
-
-
Verkhratsky, A.1
Parpura, V.2
-
118
-
-
23044435896
-
Astrocytes, from brain glue to communication elements: The revolution continues
-
DOI 10.1038/nrn1722
-
Volterra A, Meldolesi J (2005) Astrocytes, from brain glue to communication elements: the revolution continues. Nat Rev Neurosci 6:626-640 (Pubitemid 41059337)
-
(2005)
Nature Reviews Neuroscience
, vol.6
, Issue.8
, pp. 626-640
-
-
Volterra, A.1
Meldolesi, J.2
-
119
-
-
65249157852
-
Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
-
Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J (2009) Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J Neurosci 29:3974-3980
-
(2009)
J Neurosci
, vol.29
, pp. 3974-3980
-
-
Wake, H.1
Moorhouse, A.J.2
Jinno, S.3
Kohsaka, S.4
Nabekura, J.5
-
120
-
-
77249158836
-
Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation
-
Wu HY, Hudry E, Hashimoto T, Kuchibhotla K, Rozkalne A, Fan Z, Spires-Jones T, Xie H, Arbel-Ornath M, Grosskreutz CL, Bacskai BJ, Hyman BT (2010) Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation. J Neurosci 30:2636-2649
-
(2010)
J Neurosci
, vol.30
, pp. 2636-2649
-
-
Wu, H.Y.1
Hudry, E.2
Hashimoto, T.3
Kuchibhotla, K.4
Rozkalne, A.5
Fan, Z.6
Spires-Jones, T.7
Xie, H.8
Arbel-Ornath, M.9
Grosskreutz, C.L.10
Bacskai, B.J.11
Hyman, B.T.12
-
121
-
-
84875655895
-
Inflammation in Alzheimer disease - A brief review of the basic science and clinical literature
-
Wyss-Coray T, Rogers J (2012) Inflammation in Alzheimer disease - a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med 2:a006346
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
-
-
Wyss-Coray, T.1
Rogers, J.2
|