메뉴 건너뛰기




Volumn 23, Issue 11, 2003, Pages 4410-4419

Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): Suppression of receptor-evoked calcium signaling and control of release function

Author keywords

BAPTA; C5a; CD88; Fura 2; Ionomycin; UTP

Indexed keywords

CALCIUM; CHELATING AGENT; CHEMOKINE; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; IONOMYCIN; NITRIC OXIDE;

EID: 0038795206     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-11-04410.2003     Document Type: Article
Times cited : (226)

References (52)
  • 1
    • 0029000480 scopus 로고
    • Effect of bacterial wall lipopolysaccharide (LPS) on morphology, motility, and cytoskeletal organization of microglia in cultures
    • abd-el-Basset E, Fedoroff S (1995) Effect of bacterial wall lipopolysaccharide (LPS) on morphology, motility, and cytoskeletal organization of microglia in cultures. J Neurosci Res 41:222-237.
    • (1995) J Neurosci Res , vol.41 , pp. 222-237
    • Abd-El-Basset, E.1    Fedoroff, S.2
  • 2
    • 0029041609 scopus 로고
    • Calcium-dependent nitric oxide formation in glial cells
    • Agullo L, Baltrons MA, Garcia A (1995) Calcium-dependent nitric oxide formation in glial cells. Brain Res 686:160-168.
    • (1995) Brain Res , vol.686 , pp. 160-168
    • Agullo, L.1    Baltrons, M.A.2    Garcia, A.3
  • 4
    • 0035129651 scopus 로고    scopus 로고
    • Activation an anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive
    • Benschop RJ, Aviszus K, Zhang X, Manser T, Cambier JC, Wysocki LJ (2001) Activation an anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. Immunity 14:33-43.
    • (2001) Immunity , vol.14 , pp. 33-43
    • Benschop, R.J.1    Aviszus, K.2    Zhang, X.3    Manser, T.4    Cambier, J.C.5    Wysocki, L.J.6
  • 5
    • 0035224759 scopus 로고    scopus 로고
    • The versatility and complexity of calcium signalling
    • Berridge MJ (2001) The versatility and complexity of calcium signalling. Novartis Found Symp 239:52-64.
    • (2001) Novartis Found Symp , vol.239 , pp. 52-64
    • Berridge, M.J.1
  • 7
    • 0037013740 scopus 로고    scopus 로고
    • Effect of hyperglycemia on the basal cytosolic free calcium level, calcium signal and tyrosine-phosphorylation in human T cells
    • Boldizsar F, Berki T, Miseta A, Nemeth P (2002) Effect of hyperglycemia on the basal cytosolic free calcium level, calcium signal and tyrosine-phosphorylation in human T cells. Immunol Lett 82:159-164.
    • (2002) Immunol Lett , vol.82 , pp. 159-164
    • Boldizsar, F.1    Berki, T.2    Miseta, A.3    Nemeth, P.4
  • 9
    • 0031031213 scopus 로고    scopus 로고
    • Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system
    • Gasque P, Singhrao SK, Neal JW, Gotze O, Morgan BP (1997) Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. Am J Pathol 150:31-41.
    • (1997) Am J Pathol , vol.150 , pp. 31-41
    • Gasque, P.1    Singhrao, S.K.2    Neal, J.W.3    Gotze, O.4    Morgan, B.P.5
  • 10
    • 0028978604 scopus 로고
    • 2+ selectively suppresses IL-1-induced NO production by reducing iNOS mRNA stability
    • 2+ selectively suppresses IL-1-induced NO production by reducing iNOS mRNA stability. J Cell Biol 129:1651-1657.
    • (1995) J Cell Biol , vol.129 , pp. 1651-1657
    • Geng, Y.1    Lotz, M.2
  • 11
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 12
    • 0035104119 scopus 로고    scopus 로고
    • LPS induction of gene expression in human monocytes
    • Guha M, Mackman N (2001) LPS induction of gene expression in human monocytes. Cell Signal 13:85-94.
    • (2001) Cell Signal , vol.13 , pp. 85-94
    • Guha, M.1    Mackman, N.2
  • 13
    • 0002473706 scopus 로고    scopus 로고
    • Microglia as a source and target of cytokine activities in the brain
    • Streit WJ, ed. New York: Springer
    • Hanisch UK (2001) Microglia as a source and target of cytokine activities in the brain. In: Microglia in the degenerating and regenerating CNS (Streit WJ, ed), pp 79-124. New York: Springer.
    • (2001) Microglia in the Degenerating and Regenerating CNS , pp. 79-124
    • Hanisch, U.K.1
  • 14
    • 0036849018 scopus 로고    scopus 로고
    • Microlgia as a source and target of cytokines
    • Hanisch UK (2002) Microlgia as a source and target of cytokines. Glia 40:140-155.
    • (2002) Glia , vol.40 , pp. 140-155
    • Hanisch, U.K.1
  • 15
    • 0034945260 scopus 로고    scopus 로고
    • The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls
    • Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR (2001) The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls. Eur J Immunol 31:2104-2115.
    • (2001) Eur J Immunol , vol.31 , pp. 2104-2115
    • Hanisch, U.K.1    Prinz, M.2    Angstwurm, K.3    Hausler, K.G.4    Kann, O.5    Kettenmann, H.6    Weber, J.R.7
  • 17
    • 18744390011 scopus 로고    scopus 로고
    • Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages
    • Häusler KG, Prinz M, Nolte C, Weber JR, Schumann RR, Kettenmann H, Hanisch UK (2002) Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages. Eur J Neurosci 16:2113-2122.
    • (2002) Eur J Neurosci , vol.16 , pp. 2113-2122
    • Häusler, K.G.1    Prinz, M.2    Nolte, C.3    Weber, J.R.4    Schumann, R.R.5    Kettenmann, H.6    Hanisch, U.K.7
  • 20
    • 0028800715 scopus 로고
    • Cytokines and the nervous system. I. Expression and recognition
    • Hopkins SJ, Rothwell NJ (1995) Cytokines and the nervous system. I. Expression and recognition. Trends Neurosci 18:83-88.
    • (1995) Trends Neurosci , vol.18 , pp. 83-88
    • Hopkins, S.J.1    Rothwell, N.J.2
  • 21
    • 0031774181 scopus 로고    scopus 로고
    • Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
    • Kirschning CJ, Wesche H, Merrill AT, Rothe M (1998) Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med 188:2091-2097.
    • (1998) J Exp Med , vol.188 , pp. 2091-2097
    • Kirschning, C.J.1    Wesche, H.2    Merrill, A.T.3    Rothe, M.4
  • 22
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 24
    • 0033015299 scopus 로고    scopus 로고
    • Treatment of the macrophage-like P388D.1 cells with bacterial lipopolysaccharide and interferongamma causes long-term alterations in calcium metabolism
    • Lowry MA, Goldberg JI, Belosevic M (1999) Treatment of the macrophage-like P388D.1 cells with bacterial lipopolysaccharide and interferongamma causes long-term alterations in calcium metabolism. Dev Comp Immunol 23:253-261.
    • (1999) Dev Comp Immunol , vol.23 , pp. 253-261
    • Lowry, M.A.1    Goldberg, J.I.2    Belosevic, M.3
  • 25
    • 0031717069 scopus 로고    scopus 로고
    • Differential kinetics for induction of interleukin-6 mRNA expression in murine peritoneal macrophages: Evidence for calcium-dependent and independent signalling pathways
    • Marriott I, Bost KL, Mason MJ (1998) Differential kinetics for induction of interleukin-6 mRNA expression in murine peritoneal macrophages: evidence for calcium-dependent and independent signalling pathways. J Cell Physiol 177:232-240.
    • (1998) J Cell Physiol , vol.177 , pp. 232-240
    • Marriott, I.1    Bost, K.L.2    Mason, M.J.3
  • 26
    • 0030056101 scopus 로고    scopus 로고
    • Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery
    • Martinez MC, Muller B, Stoclet JC, Andriantsitohaina R (1996) Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery. Br J Pharmacol 118:1218-1222.
    • (1996) Br J Pharmacol , vol.118 , pp. 1218-1222
    • Martinez, M.C.1    Muller, B.2    Stoclet, J.C.3    Andriantsitohaina, R.4
  • 27
    • 0026570528 scopus 로고
    • β-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE (1992) β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 12:376-389.
    • (1992) J Neurosci , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.E.6
  • 28
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE, Benveniste EN (1996) Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 19:331-338.
    • (1996) Trends Neurosci , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 30
    • 0033822556 scopus 로고    scopus 로고
    • Thrombin-induced activation of cultured rodent microglia
    • Möller T, Hanisch UK, Ransom BR (2000a) Thrombin-induced activation of cultured rodent microglia. J Neurochem 75:1539-1547.
    • (2000) J Neurochem , vol.75 , pp. 1539-1547
    • Möller, T.1    Hanisch, U.K.2    Ransom, B.R.3
  • 31
    • 0141769473 scopus 로고    scopus 로고
    • Activation of mouse microglial cells affects P2 receptor signaling
    • Möller T, Kann O, Verkhratsky A, Kettenmann H (2000b) Activation of mouse microglial cells affects P2 receptor signaling. Brain Res 853:49-59.
    • (2000) Brain Res , vol.853 , pp. 49-59
    • Möller, T.1    Kann, O.2    Verkhratsky, A.3    Kettenmann, H.4
  • 32
    • 0033198678 scopus 로고    scopus 로고
    • Complement anaphylatoxin receptors on neurons: New tricks for old receptors?
    • Nataf S, Stahel PF, Davoust N, Barnum SR (1999) Complement anaphylatoxin receptors on neurons: new tricks for old receptors? Trends Neurosci 22:397-402.
    • (1999) Trends Neurosci , vol.22 , pp. 397-402
    • Nataf, S.1    Stahel, P.F.2    Davoust, N.3    Barnum, S.R.4
  • 33
    • 0034001914 scopus 로고    scopus 로고
    • AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia
    • Noda M, Nakanishi H, Nabekura J, Akaike N (2000). AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia. J Neurosci 20:251-258.
    • (2000) J Neurosci , vol.20 , pp. 251-258
    • Noda, M.1    Nakanishi, H.2    Nabekura, J.3    Akaike, N.4
  • 34
    • 0342592138 scopus 로고    scopus 로고
    • Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton
    • Nolte C, Moller T, Walter T, Kettenmann H (1996) Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton. Neuroscience 73:1091-1107.
    • (1996) Neuroscience , vol.73 , pp. 1091-1107
    • Nolte, C.1    Moller, T.2    Walter, T.3    Kettenmann, H.4
  • 35
    • 0028203597 scopus 로고
    • Voltage-dependent potassium channels in activated rat microglia
    • Nörenberg W, Gebicke-Haerter PJ, Illes P (1994) Voltage-dependent potassium channels in activated rat microglia. J Physiol (Lond) 475:15-32.
    • (1994) J Physiol (Lond) , vol.475 , pp. 15-32
    • Nörenberg, W.1    Gebicke-Haerter, P.J.2    Illes, P.3
  • 36
    • 0032866588 scopus 로고    scopus 로고
    • Microglial activation by components of Gram-positive and -negative bacteria: Distinct and common routes to the induction of ion channels and cytokines
    • Prinz M, Kann O, Draheim HJ, Schumann RR, Kettenmann H, Weber JR, Hanisch UK (1999) Microglial activation by components of Gram-positive and -negative bacteria: distinct and common routes to the induction of ion channels and cytokines. J Neuropathol Exp Neurol 58:1078-1089.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 1078-1089
    • Prinz, M.1    Kann, O.2    Draheim, H.J.3    Schumann, R.R.4    Kettenmann, H.5    Weber, J.R.6    Hanisch, U.K.7
  • 37
    • 0035957814 scopus 로고    scopus 로고
    • β-adrenergic receptor stimulation selectively inhibits IL-12p40 release in microglia
    • Prinz M, Häusler KG, Kettenmann H, Hanisch UK (2001) β-adrenergic receptor stimulation selectively inhibits IL-12p40 release in microglia. Brain Res 899:264-270.
    • (2001) Brain Res , vol.899 , pp. 264-270
    • Prinz, M.1    Häusler, K.G.2    Kettenmann, H.3    Hanisch, U.K.4
  • 38
    • 0028327718 scopus 로고
    • Role of calcium in the activation of mouse peritoneal macrophages: Induction of NO synthase by calcium ionophores and thapsigargin
    • Raddassi K, Berthon B, Petit JF, Lemaire G (1994) Role of calcium in the activation of mouse peritoneal macrophages: induction of NO synthase by calcium ionophores and thapsigargin. Cell Immunol 153:443-455.
    • (1994) Cell Immunol , vol.153 , pp. 443-455
    • Raddassi, K.1    Berthon, B.2    Petit, J.F.3    Lemaire, G.4
  • 39
    • 0032496710 scopus 로고    scopus 로고
    • Regulation of MCSF receptors on microglia in the normal and injured mouse central nervous system: A quantitative immunofluorescence study using confocal laser microscopy
    • Raivich G, Haas S, Werner A, Klein MA, Kloss C, Kreutzberg GW (1998) Regulation of MCSF receptors on microglia in the normal and injured mouse central nervous system: a quantitative immunofluorescence study using confocal laser microscopy. J Comp Neurol 395:342-358.
    • (1998) J Comp Neurol , vol.395 , pp. 342-358
    • Raivich, G.1    Haas, S.2    Werner, A.3    Klein, M.A.4    Kloss, C.5    Kreutzberg, G.W.6
  • 40
    • 0032814562 scopus 로고    scopus 로고
    • Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function
    • Raivich G, Bohatschek M, Kloss CU, Werner A, Jones LL, Kreutzberg GW (1999a) Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 30:77-105.
    • (1999) Brain Res Brain Res Rev , vol.30 , pp. 77-105
    • Raivich, G.1    Bohatschek, M.2    Kloss, C.U.3    Werner, A.4    Jones, L.L.5    Kreutzberg, G.W.6
  • 42
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413-492.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 47
    • 0032519934 scopus 로고    scopus 로고
    • Lipopolysaccharide regulates both serotonin- and thrombin-induced intracellular calcium mobilization in rat C6 glioma cells: Possible involvement of nitric oxide synthase-mediated pathway
    • Tawara Y, Kagaya A, Uchitomi Y, Horiguchi I, Yamawaki S (1998) Lipopolysaccharide regulates both serotonin- and thrombin-induced intracellular calcium mobilization in rat C6 glioma cells: possible involvement of nitric oxide synthase-mediated pathway. J Neurosci Res 51:517-525.
    • (1998) J Neurosci Res , vol.51 , pp. 517-525
    • Tawara, Y.1    Kagaya, A.2    Uchitomi, Y.3    Horiguchi, I.4    Yamawaki, S.5
  • 49
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • Ulevitch RJ, Tobias PS (1995) Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu Rev Immunol 13:437-457.
    • (1995) Annu Rev Immunol , vol.13 , pp. 437-457
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 50
    • 0034052110 scopus 로고    scopus 로고
    • Expression of receptors for complement anaphylatoxins C3a and C5a following permanent focal cerebral ischemia in the mouse
    • Van Beek J, Bernaudin M, Petit E, Gasque P, Nouvelot A, MacKenzie ET, Fontaine M (2000) Expression of receptors for complement anaphylatoxins C3a and C5a following permanent focal cerebral ischemia in the mouse. Exp Neurol 161:373-382.
    • (2000) Exp Neurol , vol.161 , pp. 373-382
    • Van Beek, J.1    Bernaudin, M.2    Petit, E.3    Gasque, P.4    Nouvelot, A.5    MacKenzie, E.T.6    Fontaine, M.7
  • 52
    • 0031893563 scopus 로고    scopus 로고
    • Glial calcium: Homeostasis and signaling function
    • Verkhratsky A, Orkand RK, Kettenmann H (1998) Glial calcium: homeostasis and signaling function. Physiol Rev 78:99-141.
    • (1998) Physiol Rev , vol.78 , pp. 99-141
    • Verkhratsky, A.1    Orkand, R.K.2    Kettenmann, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.