-
1
-
-
34548402098
-
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells
-
Intlekofer AM, Takemoto N, Kao C, Banerjee A, Schambach F, et al. (2007) Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells. The Journal of experimental medicine 204: 2015-2021.
-
(2007)
The Journal of Experimental Medicine
, vol.204
, pp. 2015-2021
-
-
Intlekofer, A.M.1
Takemoto, N.2
Kao, C.3
Banerjee, A.4
Schambach, F.5
-
2
-
-
30044440799
-
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
-
Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, et al. (2005) Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nature immunology 6: 1236-1244.
-
(2005)
Nature Immunology
, vol.6
, pp. 1236-1244
-
-
Intlekofer, A.M.1
Takemoto, N.2
Wherry, E.J.3
Longworth, S.A.4
Northrup, J.T.5
-
3
-
-
0242410712
-
Control of effector CD8+ T cell function by the transcription factor Eomesodermin
-
Pearce EL, Mullen AC, Martins GA, Krawczyk CM, Hutchins AS, et al. (2003) Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science 302: 1041-1043.
-
(2003)
Science
, vol.302
, pp. 1041-1043
-
-
Pearce, E.L.1
Mullen, A.C.2
Martins, G.A.3
Krawczyk, C.M.4
Hutchins, A.S.5
-
4
-
-
78149490392
-
Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche
-
Banerjee A, Gordon SM, Intlekofer AM, Paley MA, Mooney EC, et al. (2010) Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche. Journal of immunology 185: 4988-4992.
-
(2010)
Journal of Immunology
, vol.185
, pp. 4988-4992
-
-
Banerjee, A.1
Gordon, S.M.2
Intlekofer, A.M.3
Paley, M.A.4
Mooney, E.C.5
-
5
-
-
34548027000
-
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
-
Joshi NS, Cui W, Chandele A, Lee HK, Urso DR, et al. (2007) Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 27: 281-295.
-
(2007)
Immunity
, vol.27
, pp. 281-295
-
-
Joshi, N.S.1
Cui, W.2
Chandele, A.3
Lee, H.K.4
Urso, D.R.5
-
6
-
-
80054722812
-
Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells
-
Joshi NS, Cui W, Dominguez CX, Chen JH, Hand TW, et al. (2011) Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells. Journal of immunology 187: 4068-4076.
-
(2011)
Journal of Immunology
, vol.187
, pp. 4068-4076
-
-
Joshi, N.S.1
Cui, W.2
Dominguez, C.X.3
Chen, J.H.4
Hand, T.W.5
-
7
-
-
77955869484
-
Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1
-
Zhou X, Yu S, Zhao DM, Harty JT, Badovinac VP, et al. (2010) Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1. Immunity 33: 229-240.
-
(2010)
Immunity
, vol.33
, pp. 229-240
-
-
Zhou, X.1
Yu, S.2
Zhao, D.M.3
Harty, J.T.4
Badovinac, V.P.5
-
8
-
-
84867896903
-
Transcriptional control of effector and memory CD8+ T cell differentiation
-
Kaech SM, Cui W, (2012) Transcriptional control of effector and memory CD8+ T cell differentiation. Nature reviews Immunology 12: 749-761.
-
(2012)
Nature Reviews Immunology
, vol.12
, pp. 749-761
-
-
Kaech, S.M.1
Cui, W.2
-
9
-
-
0037383592
-
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
-
Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R, (2003) Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. Journal of virology 77: 4911-4927.
-
(2003)
Journal of Virology
, vol.77
, pp. 4911-4927
-
-
Wherry, E.J.1
Blattman, J.N.2
Murali-Krishna, K.3
van der Most, R.4
Ahmed, R.5
-
10
-
-
0032416085
-
Viral immune evasion due to persistence of activated T cells without effector function
-
Zajac AJ, Blattman JN, Murali-Krishna K, Sourdive DJ, Suresh M, et al. (1998) Viral immune evasion due to persistence of activated T cells without effector function. The Journal of experimental medicine 188: 2205-2213.
-
(1998)
The Journal of Experimental Medicine
, vol.188
, pp. 2205-2213
-
-
Zajac, A.J.1
Blattman, J.N.2
Murali-Krishna, K.3
Sourdive, D.J.4
Suresh, M.5
-
11
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, et al. (2006) Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
-
12
-
-
57849168934
-
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
-
Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, et al. (2009) Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nature immunology 10: 29-37.
-
(2009)
Nature Immunology
, vol.10
, pp. 29-37
-
-
Blackburn, S.D.1
Shin, H.2
Haining, W.N.3
Zou, T.4
Workman, C.J.5
-
13
-
-
33749009709
-
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
-
Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, et al. (2006) Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nature medicine 12: 1198-1202.
-
(2006)
Nature Medicine
, vol.12
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
-
14
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, et al. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350-354.
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
-
15
-
-
33749338938
-
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
-
Petrovas C, Casazza JP, Brenchley JM, Price DA, Gostick E, et al. (2006) PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. The Journal of experimental medicine 203: 2281-2292.
-
(2006)
The Journal of Experimental Medicine
, vol.203
, pp. 2281-2292
-
-
Petrovas, C.1
Casazza, J.P.2
Brenchley, J.M.3
Price, D.A.4
Gostick, E.5
-
16
-
-
79955955402
-
Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection
-
Yamamoto T, Price DA, Casazza JP, Ferrari G, Nason M, et al. (2011) Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. Blood 117: 4805-4815.
-
(2011)
Blood
, vol.117
, pp. 4805-4815
-
-
Yamamoto, T.1
Price, D.A.2
Casazza, J.P.3
Ferrari, G.4
Nason, M.5
-
17
-
-
33750691709
-
PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
-
Urbani S, Amadei B, Tola D, Massari M, Schivazappa S, et al. (2006) PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion. Journal of virology 80: 11398-11403.
-
(2006)
Journal of Virology
, vol.80
, pp. 11398-11403
-
-
Urbani, S.1
Amadei, B.2
Tola, D.3
Massari, M.4
Schivazappa, S.5
-
18
-
-
33947407689
-
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression
-
Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, et al. (2007) Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. Journal of virology 81: 2545-2553.
-
(2007)
Journal of Virology
, vol.81
, pp. 2545-2553
-
-
Radziewicz, H.1
Ibegbu, C.C.2
Fernandez, M.L.3
Workowski, K.A.4
Obideen, K.5
-
19
-
-
33947421722
-
Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection
-
Penna A, Pilli M, Zerbini A, Orlandini A, Mezzadri S, et al. (2007) Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection. Hepatology 45: 588-601.
-
(2007)
Hepatology
, vol.45
, pp. 588-601
-
-
Penna, A.1
Pilli, M.2
Zerbini, A.3
Orlandini, A.4
Mezzadri, S.5
-
20
-
-
84892727073
-
Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors
-
Kroy DC, Ciuffreda D, Cooperider JH, Tomlinson M, Hauck GD, et al. (2013) Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors. Gastroenterology 146: 550-61.
-
(2013)
Gastroenterology
, vol.146
, pp. 550-561
-
-
Kroy, D.C.1
Ciuffreda, D.2
Cooperider, J.H.3
Tomlinson, M.4
Hauck, G.D.5
-
21
-
-
34247117935
-
Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection
-
Boni C, Fisicaro P, Valdatta C, Amadei B, Di Vincenzo P, et al. (2007) Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection. Journal of virology 81: 4215-4225.
-
(2007)
Journal of Virology
, vol.81
, pp. 4215-4225
-
-
Boni, C.1
Fisicaro, P.2
Valdatta, C.3
Amadei, B.4
Di Vincenzo, P.5
-
22
-
-
35648968689
-
PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
-
Peng G, Li S, Wu W, Tan X, Chen Y, et al. (2008) PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients. Molecular immunology 45: 963-970.
-
(2008)
Molecular Immunology
, vol.45
, pp. 963-970
-
-
Peng, G.1
Li, S.2
Wu, W.3
Tan, X.4
Chen, Y.5
-
23
-
-
78649625973
-
The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function
-
Raziorrouh B, Schraut W, Gerlach T, Nowack D, Gruner NH, et al. (2010) The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function. Hepatology 52: 1934-1947.
-
(2010)
Hepatology
, vol.52
, pp. 1934-1947
-
-
Raziorrouh, B.1
Schraut, W.2
Gerlach, T.3
Nowack, D.4
Gruner, N.H.5
-
24
-
-
34948906159
-
Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
-
Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
-
(2007)
J Exp Med
, vol.204
, pp. 2473-2485
-
-
Almeida, J.R.1
Price, D.A.2
Papagno, L.3
Arkoub, Z.A.4
Sauce, D.5
-
25
-
-
33646686040
-
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
-
Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, et al. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107: 4781-4789.
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
De Rosa, S.C.4
Migueles, S.A.5
-
26
-
-
0036109159
-
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections
-
Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, et al. (2002) Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nature medicine 8: 379-385.
-
(2002)
Nature Medicine
, vol.8
, pp. 379-385
-
-
Appay, V.1
Dunbar, P.R.2
Callan, M.3
Klenerman, P.4
Gillespie, G.M.5
-
27
-
-
0035282444
-
Skewed maturation of memory HIV-specific CD8 T lymphocytes
-
Champagne P, Ogg GS, King AS, Knabenhans C, Ellefsen K, et al. (2001) Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 410: 106-111.
-
(2001)
Nature
, vol.410
, pp. 106-111
-
-
Champagne, P.1
Ogg, G.S.2
King, A.S.3
Knabenhans, C.4
Ellefsen, K.5
-
28
-
-
84870922385
-
Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory
-
Doering TA, Crawford A, Angelosanto JM, Paley MA, Ziegler CG, et al. (2012) Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory. Immunity 37: 1130-1144.
-
(2012)
Immunity
, vol.37
, pp. 1130-1144
-
-
Doering, T.A.1
Crawford, A.2
Angelosanto, J.M.3
Paley, M.A.4
Ziegler, C.G.5
-
29
-
-
77957781776
-
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
-
Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, et al. (2010) Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF. Nature medicine 16: 1147-1151.
-
(2010)
Nature Medicine
, vol.16
, pp. 1147-1151
-
-
Quigley, M.1
Pereyra, F.2
Nilsson, B.3
Porichis, F.4
Fonseca, C.5
-
30
-
-
84866176745
-
CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction
-
Peretz Y, He Z, Shi Y, Yassine-Diab B, Goulet JP, et al. (2012) CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction. PLoS pathogens 8: e1002840.
-
(2012)
PLoS Pathogens
, vol.8
-
-
Peretz, Y.1
He, Z.2
Shi, Y.3
Yassine-Diab, B.4
Goulet, J.P.5
-
31
-
-
84870230232
-
Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection
-
Paley MA, Kroy DC, Odorizzi PM, Johnnidis JB, Dolfi DV, et al. (2012) Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection. Science 338: 1220-1225.
-
(2012)
Science
, vol.338
, pp. 1220-1225
-
-
Paley, M.A.1
Kroy, D.C.2
Odorizzi, P.M.3
Johnnidis, J.B.4
Dolfi, D.V.5
-
32
-
-
79959375167
-
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
-
Kao C, Oestreich KJ, Paley MA, Crawford A, Angelosanto JM, et al. (2011) Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection. Nature immunology 12: 663-671.
-
(2011)
Nature Immunology
, vol.12
, pp. 663-671
-
-
Kao, C.1
Oestreich, K.J.2
Paley, M.A.3
Crawford, A.4
Angelosanto, J.M.5
-
33
-
-
79953815120
-
Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression
-
Hersperger AR, Martin JN, Shin LY, Sheth PM, Kovacs CM, et al. (2011) Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression. Blood 117: 3799-3808.
-
(2011)
Blood
, vol.117
, pp. 3799-3808
-
-
Hersperger, A.R.1
Martin, J.N.2
Shin, L.Y.3
Sheth, P.M.4
Kovacs, C.M.5
-
34
-
-
0142185336
-
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
-
Betts MR, Brenchley JM, Price DA, De Rosa SC, Douek DC, et al. (2003) Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. Journal of immunological methods 281: 65-78.
-
(2003)
Journal of Immunological Methods
, vol.281
, pp. 65-78
-
-
Betts, M.R.1
Brenchley, J.M.2
Price, D.A.3
De Rosa, S.C.4
Douek, D.C.5
-
35
-
-
84901267835
-
Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression
-
Buggert M, Norstrom MM, Salemi M, Hecht FM, Karlsson AC, (2014) Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression. Journal of immunology 192: 4685-4696.
-
(2014)
Journal of Immunology
, vol.192
, pp. 4685-4696
-
-
Buggert, M.1
Norstrom, M.M.2
Salemi, M.3
Hecht, F.M.4
Karlsson, A.C.5
-
36
-
-
84866150144
-
Combination of immune and viral factors distinguishes low-risk versus high-risk HIV-1 disease progression in HLA-B*5701 subjects
-
Norstrom MM, Buggert M, Tauriainen J, Hartogensis W, Prosperi MC, et al. (2012) Combination of immune and viral factors distinguishes low-risk versus high-risk HIV-1 disease progression in HLA-B*5701 subjects. Journal of virology 86: 9802-9816.
-
(2012)
Journal of Virology
, vol.86
, pp. 9802-9816
-
-
Norstrom, M.M.1
Buggert, M.2
Tauriainen, J.3
Hartogensis, W.4
Prosperi, M.C.5
-
37
-
-
84863304598
-
-
R Core Team, R Foundation for Statistical Computing V, Austria. ISBN 3-900051-07-0, URL
-
R Core Team (2012). R: A language and environment for statistical computing. R Foundation for Statistical Computing V, Austria. ISBN 3-900051-07-0, URL http://www.R-project.org/.
-
(2012)
R: A language and environment for statistical computing
-
-
-
39
-
-
79961006794
-
Responsiveness of HIV-specific CD4 T cells to PD-1 blockade
-
Porichis F, Kwon DS, Zupkosky J, Tighe DP, McMullen A, et al. (2011) Responsiveness of HIV-specific CD4 T cells to PD-1 blockade. Blood 118: 965-974.
-
(2011)
Blood
, vol.118
, pp. 965-974
-
-
Porichis, F.1
Kwon, D.S.2
Zupkosky, J.3
Tighe, D.P.4
McMullen, A.5
-
40
-
-
58149277359
-
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, et al. (2008) Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. The Journal of experimental medicine 205: 2763-2779.
-
(2008)
The Journal of Experimental Medicine
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
Ndhlovu, L.C.2
Barbour, J.D.3
Sheth, P.M.4
Jha, A.R.5
-
41
-
-
84868088804
-
Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells
-
Smith C, Elhassen D, Gras S, Wynn KK, Dasari V, et al. (2012) Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells. Blood 120: 3237-3245.
-
(2012)
Blood
, vol.120
, pp. 3237-3245
-
-
Smith, C.1
Elhassen, D.2
Gras, S.3
Wynn, K.K.4
Dasari, V.5
-
42
-
-
84863615191
-
Characterization of HIV-specific CD4+ T cell responses against peptides selected with broad population and pathogen coverage
-
Buggert M, Norstrom MM, Czarnecki C, Tupin E, Luo M, et al. (2012) Characterization of HIV-specific CD4+ T cell responses against peptides selected with broad population and pathogen coverage. PloS one 7: e39874.
-
(2012)
PloS One
, vol.7
-
-
Buggert, M.1
Norstrom, M.M.2
Czarnecki, C.3
Tupin, E.4
Luo, M.5
-
43
-
-
63149122367
-
Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure
-
Harari A, Enders FB, Cellerai C, Bart PA, Pantaleo G, (2009) Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure. Journal of virology 83: 2862-2871.
-
(2009)
Journal of Virology
, vol.83
, pp. 2862-2871
-
-
Harari, A.1
Enders, F.B.2
Cellerai, C.3
Bart, P.A.4
Pantaleo, G.5
-
44
-
-
77950422606
-
Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells
-
Makedonas G, Hutnick N, Haney D, Amick AC, Gardner J, et al. (2010) Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells. PLoS pathogens 6: e1000798.
-
(2010)
PLoS Pathogens
, vol.6
-
-
Makedonas, G.1
Hutnick, N.2
Haney, D.3
Amick, A.C.4
Gardner, J.5
-
45
-
-
44449117504
-
Broadly immunogenic HLA class I supertype-restricted elite CTL epitopes recognized in a diverse population infected with different HIV-1 subtypes
-
Perez CL, Larsen MV, Gustafsson R, Norstrom MM, Atlas A, et al. (2008) Broadly immunogenic HLA class I supertype-restricted elite CTL epitopes recognized in a diverse population infected with different HIV-1 subtypes. Journal of immunology 180: 5092-5100.
-
(2008)
Journal of Immunology
, vol.180
, pp. 5092-5100
-
-
Perez, C.L.1
Larsen, M.V.2
Gustafsson, R.3
Norstrom, M.M.4
Atlas, A.5
-
46
-
-
84896519361
-
Multiparametric bioinformatics distinguish the CD4/CD8 ratio as a suitable laboratory predictor of combined T cell pathogenesis in HIV infection
-
Buggert M, Frederiksen J, Noyan K, Svard J, Barqasho B, et al. (2014) Multiparametric bioinformatics distinguish the CD4/CD8 ratio as a suitable laboratory predictor of combined T cell pathogenesis in HIV infection. Journal of immunology 192: 2099-2108.
-
(2014)
Journal of Immunology
, vol.192
, pp. 2099-2108
-
-
Buggert, M.1
Frederiksen, J.2
Noyan, K.3
Svard, J.4
Barqasho, B.5
-
47
-
-
33751584436
-
Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation
-
Takemoto N, Intlekofer AM, Northrup JT, Wherry EJ, Reiner SL, (2006) Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation. Journal of immunology 177: 7515-7519.
-
(2006)
Journal of Immunology
, vol.177
, pp. 7515-7519
-
-
Takemoto, N.1
Intlekofer, A.M.2
Northrup, J.T.3
Wherry, E.J.4
Reiner, S.L.5
-
48
-
-
84885156779
-
Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-beta1 signaling
-
Grange M, Verdeil G, Arnoux F, Griffon A, Spicuglia S, et al. (2013) Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-beta1 signaling. Journal of immunology 191: 3712-3724.
-
(2013)
Journal of Immunology
, vol.191
, pp. 3712-3724
-
-
Grange, M.1
Verdeil, G.2
Arnoux, F.3
Griffon, A.4
Spicuglia, S.5
-
49
-
-
84879301315
-
CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis
-
Demers KR, Reuter MA, Betts MR, (2013) CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis. Immunological reviews 254: 190-206.
-
(2013)
Immunological Reviews
, vol.254
, pp. 190-206
-
-
Demers, K.R.1
Reuter, M.A.2
Betts, M.R.3
-
50
-
-
84875465622
-
Differential localization of T-bet and Eomes in CD8 T cell memory populations
-
McLane LM, Banerjee PP, Cosma GL, Makedonas G, Wherry EJ, et al. (2013) Differential localization of T-bet and Eomes in CD8 T cell memory populations. Journal of immunology 190: 3207-3215.
-
(2013)
Journal of Immunology
, vol.190
, pp. 3207-3215
-
-
McLane, L.M.1
Banerjee, P.P.2
Cosma, G.L.3
Makedonas, G.4
Wherry, E.J.5
-
51
-
-
84861485733
-
Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors
-
Ribeiro-dos-Santos P, Turnbull EL, Monteiro M, Legrand A, Conrod K, et al. (2012) Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors. Blood 119: 4928-4938.
-
(2012)
Blood
, vol.119
, pp. 4928-4938
-
-
Ribeiro-dos-Santos, P.1
Turnbull, E.L.2
Monteiro, M.3
Legrand, A.4
Conrod, K.5
-
52
-
-
57449109484
-
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control
-
Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, et al. (2008) Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity 29: 1009-1021.
-
(2008)
Immunity
, vol.29
, pp. 1009-1021
-
-
Migueles, S.A.1
Osborne, C.M.2
Royce, C.3
Compton, A.A.4
Joshi, R.P.5
-
53
-
-
77954080011
-
Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control
-
Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, et al. (2010) Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. PLoS pathogens 6: e1000917.
-
(2010)
PLoS Pathogens
, vol.6
-
-
Hersperger, A.R.1
Pereyra, F.2
Nason, M.3
Demers, K.4
Sheth, P.5
-
54
-
-
0036852179
-
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
-
Migueles SA, Laborico AC, Shupert WL, Sabbaghian MS, Rabin R, et al. (2002) HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. Nature immunology 3: 1061-1068.
-
(2002)
Nature Immunology
, vol.3
, pp. 1061-1068
-
-
Migueles, S.A.1
Laborico, A.C.2
Shupert, W.L.3
Sabbaghian, M.S.4
Rabin, R.5
-
55
-
-
1842631484
-
Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells
-
Wolint P, Betts MR, Koup RA, Oxenius A, (2004) Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells. The Journal of experimental medicine 199: 925-936.
-
(2004)
The Journal of Experimental Medicine
, vol.199
, pp. 925-936
-
-
Wolint, P.1
Betts, M.R.2
Koup, R.A.3
Oxenius, A.4
-
56
-
-
70449571945
-
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
-
Jenner RG, Townsend MJ, Jackson I, Sun K, Bouwman RD, et al. (2009) The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proceedings of the National Academy of Sciences of the United States of America 106: 17876-17881.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 17876-17881
-
-
Jenner, R.G.1
Townsend, M.J.2
Jackson, I.3
Sun, K.4
Bouwman, R.D.5
-
58
-
-
80053652092
-
Immunogenic and tolerogenic signatures in human immunodeficiency virus (HIV)-infected controllers compared with progressors and a conversion strategy of virus control
-
Whittall T, Peters B, Rahman D, Kingsley CI, Vaughan R, et al. (2011) Immunogenic and tolerogenic signatures in human immunodeficiency virus (HIV)-infected controllers compared with progressors and a conversion strategy of virus control. Clinical and experimental immunology 166: 208-217.
-
(2011)
Clinical and Experimental Immunology
, vol.166
, pp. 208-217
-
-
Whittall, T.1
Peters, B.2
Rahman, D.3
Kingsley, C.I.4
Vaughan, R.5
-
59
-
-
70350322293
-
Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy
-
Migueles SA, Weeks KA, Nou E, Berkley AM, Rood JE, et al. (2009) Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy. Journal of virology 83: 11876-11889.
-
(2009)
Journal of Virology
, vol.83
, pp. 11876-11889
-
-
Migueles, S.A.1
Weeks, K.A.2
Nou, E.3
Berkley, A.M.4
Rood, J.E.5
-
60
-
-
84868534523
-
Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection
-
Trautmann L, Mbitikon-Kobo FM, Goulet JP, Peretz Y, Shi Y, et al. (2012) Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection. Blood 120: 3466-3477.
-
(2012)
Blood
, vol.120
, pp. 3466-3477
-
-
Trautmann, L.1
Mbitikon-Kobo, F.M.2
Goulet, J.P.3
Peretz, Y.4
Shi, Y.5
-
61
-
-
84884374657
-
HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127
-
Hasley RB, Hong C, Li W, Friesen T, Nakamura Y, et al. (2013) HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127. AIDS 27: 1867-1877.
-
(2013)
AIDS
, vol.27
, pp. 1867-1877
-
-
Hasley, R.B.1
Hong, C.2
Li, W.3
Friesen, T.4
Nakamura, Y.5
-
62
-
-
35349014587
-
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
-
Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, et al. (2007) Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 27: 670-684.
-
(2007)
Immunity
, vol.27
, pp. 670-684
-
-
Wherry, E.J.1
Ha, S.J.2
Kaech, S.M.3
Haining, W.N.4
Sarkar, S.5
-
63
-
-
70249122418
-
Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection
-
Petrovas C, Chaon B, Ambrozak DR, Price DA, Melenhorst JJ, et al. (2009) Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection. Journal of immunology 183: 1120-1132.
-
(2009)
Journal of Immunology
, vol.183
, pp. 1120-1132
-
-
Petrovas, C.1
Chaon, B.2
Ambrozak, D.R.3
Price, D.A.4
Melenhorst, J.J.5
-
64
-
-
84878229777
-
T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion
-
Utzschneider DT, Legat A, Fuertes Marraco SA, Carrie L, Luescher I, et al. (2013) T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion. Nature immunology 14: 603-610.
-
(2013)
Nature Immunology
, vol.14
, pp. 603-610
-
-
Utzschneider, D.T.1
Legat, A.2
Fuertes Marraco, S.A.3
Carrie, L.4
Luescher, I.5
-
65
-
-
84880119204
-
Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells
-
Youngblood B, Noto A, Porichis F, Akondy RS, Ndhlovu ZM, et al. (2013) Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells. Journal of immunology 191: 540-544.
-
(2013)
Journal of Immunology
, vol.191
, pp. 540-544
-
-
Youngblood, B.1
Noto, A.2
Porichis, F.3
Akondy, R.S.4
Ndhlovu, Z.M.5
-
66
-
-
79957618772
-
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
-
Hansen SG, Ford JC, Lewis MS, Ventura AB, Hughes CM, et al. (2011) Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature 473: 523-527.
-
(2011)
Nature
, vol.473
, pp. 523-527
-
-
Hansen, S.G.1
Ford, J.C.2
Lewis, M.S.3
Ventura, A.B.4
Hughes, C.M.5
-
67
-
-
84885669019
-
Immune clearance of highly pathogenic SIV infection
-
Hansen SG, Piatak M Jr, Ventura AB, Hughes CM, Gilbride RM, et al. (2013) Immune clearance of highly pathogenic SIV infection. Nature 502: 100-104.
-
(2013)
Nature
, vol.502
, pp. 100-104
-
-
Hansen, S.G.1
Piatak Jr., M.2
Ventura, A.B.3
Hughes, C.M.4
Gilbride, R.M.5
|