The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 42, 2009, Pages 17876-17881

  Jenner, Richard G ^a   Townsend, Michael J ^b,h   Jackson, Ian ^c   Sun, Kaiming ^d,i   Bouwman, Russell D ^a   Young, Richard A ^d,e   Glimcher, Laurie H ^b,f   Lord, Graham M ^c,g  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^h GENENTECH INC   (United States)

ⁱ Aileron Therapeutics Inc   (United States)

Author keywords

Cytokines; Genomic map; T helper differentiation

Indexed keywords

TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ADHESION; ARTICLE; CELL LINEAGE; CHEMOTAXIS; CONTROLLED STUDY; GENE EXPRESSION; GENE IDENTIFICATION; GENE MAPPING; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LYMPHOCYTE DIFFERENTIATION; PRIORITY JOURNAL; PROTEIN BINDING; TH1 CELL; TH2 CELL;

CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; GATA3 TRANSCRIPTION FACTOR; GENES, MHC CLASS II; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH2 CELLS; TRANSCRIPTIONAL ACTIVATION;

EID: 70449571945     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909357106     Document Type: Article

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