Functional avidity and IL-2/perforin production is linked to the emergence of mutations within HLA-B*5701-restricted epitopes and HIV-1 disease progression

Journal of Immunology

Volumn 192, Issue 10, 2014, Pages 4685-4696

  Buggert, Marcus ^a   Norström, Melissa M ^a   Salemi, Marco ^b,c   Hecht, Frederick M ^d   Karlsson, Annika C ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; GAMMA INTERFERON; HLA B57 ANTIGEN; INTERLEUKIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NEF PROTEIN; PERFORIN; TUMOR NECROSIS FACTOR;

ARTICLE; CD8+ T LYMPHOCYTE; CELL CYCLE PROGRESSION; CELL FRACTIONATION; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DISEASE COURSE; FLOW CYTOMETRY; GAG ISW9 GENE; GAG KF11 GENE; GAG QW9 GENE; GAG TW10 GENE; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; NEF HQ10 GENE; NEF KL10 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RISK ASSESSMENT; SENSITIVITY ANALYSIS; UPREGULATION; VIRUS GENE; YT9 GENEA;

BASE SEQUENCE; CELL CYCLE; CYTOKINES; DISEASE PROGRESSION; EPITOPES; GENE PRODUCTS, GAG; HIV INFECTIONS; HIV-1; HLA-B ANTIGENS; HUMANS; INTERLEUKIN-2; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PERFORIN; UP-REGULATION;

EID: 84901267835     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302253     Document Type: Article

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