메뉴 건너뛰기




Volumn 4 MAY, Issue , 2014, Pages

MicroRNA machinery genes as novel biomarkers for cancer

Author keywords

Alterations; Biomarker; Cancer; Machinery genes; MiRNA

Indexed keywords

ARGONAUTE 2 PROTEIN; DICER; DIGEORGE CRITICAL REGION 8; DROSHA PROTEIN; EXPORTIN 5; MICRORNA; PEPTIDES AND PROTEINS; RNA BINDING PROTEIN; RNA INDUCED SILENCING COMPLEX; TAR RNA BINDING PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84904701315     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2014.00113     Document Type: Review
Times cited : (63)

References (122)
  • 1
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • doi: 10.1016/j.cell.2009.01.002
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell (2009) 136:215-33. doi: 10.1016/j.cell.2009.01.002
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • doi:10.1016/S0092-8674(04)00045-5
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 116:281-97. doi:10.1016/S0092-8674(04)00045-5
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 3
    • 84868128706 scopus 로고    scopus 로고
    • The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi
    • doi:10.1007/s00441-012-1446-0
    • Sand M, Skrygan M, Georgas D, Sand D, Gambichler T, Altmeyer P, et al. The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi. Cell Tissue Res (2012) 350:119-26. doi:10.1007/s00441-012-1446-0
    • (2012) Cell Tissue Res , vol.350 , pp. 119-126
    • Sand, M.1    Skrygan, M.2    Georgas, D.3    Sand, D.4    Gambichler, T.5    Altmeyer, P.6
  • 4
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • doi:10.1101/gr.082701.108
    • Friedman RC, Farh KK, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res (2009) 19:92-105. doi:10.1101/gr.082701.108
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 6
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • doi:10.1038/35040556
    • Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 408:86-9. doi:10.1038/35040556
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.E.1    Reinhart, B.J.2    Slack, F.3    Martindale, M.Q.4    Kuroda, M.I.5    Maller, B.6
  • 7
    • 77955475953 scopus 로고    scopus 로고
    • Expanding the microRNA targeting code: functional sites with centered pairing
    • doi:10.1016/j.molcel.2010.06.005
    • Shin C, Nam JW, Farh KK, Chiang HR, Shkumatava A, Bartel DP. Expanding the microRNA targeting code: functional sites with centered pairing. Mol Cell (2010) 38:789-802. doi:10.1016/j.molcel.2010.06.005
    • (2010) Mol Cell , vol.38 , pp. 789-802
    • Shin, C.1    Nam, J.W.2    Farh, K.K.3    Chiang, H.R.4    Shkumatava, A.5    Bartel, D.P.6
  • 8
    • 69949098536 scopus 로고    scopus 로고
    • miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements
    • doi:10.1016/j.molcel.2009.08.020
    • Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, et al. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell (2009) 35:610-25. doi:10.1016/j.molcel.2009.08.020
    • (2009) Mol Cell , vol.35 , pp. 610-625
    • Lal, A.1    Navarro, F.2    Maher, C.A.3    Maliszewski, L.E.4    Yan, N.5    O'Day, E.6
  • 9
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the microprocessor complex
    • doi:10.1038/nature03049
    • Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ. Processing of primary microRNAs by the microprocessor complex. Nature (2004) 432:231-5. doi:10.1038/nature03049
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3    Ketting, R.F.4    Hannon, G.J.5
  • 10
    • 9144225636 scopus 로고    scopus 로고
    • The microprocessor complex mediates the genesis of microRNAs
    • doi:10.1038/nature03120
    • Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, et al. The microprocessor complex mediates the genesis of microRNAs. Nature (2004) 432:235-40. doi:10.1038/nature03120
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1    Yan, K.P.2    Amuthan, G.3    Chendrimada, T.4    Doratotaj, B.5    Cooch, N.6
  • 11
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • doi:10.1038/nature01957
    • Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature (2003) 425:415-9. doi:10.1038/nature01957
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3    Choi, H.4    Kim, J.5    Yim, J.6
  • 12
    • 58149097010 scopus 로고    scopus 로고
    • Posttranscriptional crossregulation between Drosha and DGCR8
    • doi:10.1016/j.cell.2008.10.053
    • Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, et al. Posttranscriptional crossregulation between Drosha and DGCR8. Cell (2009) 136:75-84. doi:10.1016/j.cell.2008.10.053
    • (2009) Cell , vol.136 , pp. 75-84
    • Han, J.1    Pedersen, J.S.2    Kwon, S.C.3    Belair, C.D.4    Kim, Y.K.5    Yeom, K.H.6
  • 13
    • 66449118741 scopus 로고    scopus 로고
    • Post-transcriptional control of DGCR8 expression by the microprocessor
    • doi:10.1261/rna.1591709
    • Triboulet R, Chang HM, Lapierre RJ, Gregory RI. Post-transcriptional control of DGCR8 expression by the microprocessor. RNA (2009) 15:1005-11. doi:10.1261/rna.1591709
    • (2009) RNA , vol.15 , pp. 1005-1011
    • Triboulet, R.1    Chang, H.M.2    Lapierre, R.J.3    Gregory, R.I.4
  • 14
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microRNA precursors
    • doi:10.1126/science.1090599
    • Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science (2004) 303:95-8. doi:10.1126/science.1090599
    • (2004) Science , vol.303 , pp. 95-98
    • Lund, E.1    Guttinger, S.2    Calado, A.3    Dahlberg, J.E.4    Kutay, U.5
  • 15
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • doi:10.1101/gad.1158803
    • Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev (2003) 17:3011-6. doi:10.1101/gad.1158803
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 16
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • doi:10.1261/rna.5167604
    • Bohnsack MT, Czaplinski K, Gorlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA (2004) 10:185-91. doi:10.1261/rna.5167604
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 17
    • 84867678226 scopus 로고    scopus 로고
    • TRBP alters human precursor microRNA processing in vitro
    • doi:10.1261/rna.035501.112
    • Lee HY, Doudna JA. TRBP alters human precursor microRNA processing in vitro. RNA (2012) 18:2012-9. doi:10.1261/rna.035501.112
    • (2012) RNA , vol.18 , pp. 2012-2019
    • Lee, H.Y.1    Doudna, J.A.2
  • 18
    • 27144550559 scopus 로고    scopus 로고
    • TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
    • doi:10.1038/sj.embor.7400509
    • Haase AD, Jaskiewicz L, Zhang H, Laine S, Sack R, Gatignol A, et al. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep (2005) 6:961-7. doi:10.1038/sj.embor.7400509
    • (2005) EMBO Rep , vol.6 , pp. 961-967
    • Haase, A.D.1    Jaskiewicz, L.2    Zhang, H.3    Laine, S.4    Sack, R.5    Gatignol, A.6
  • 19
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    • doi:10.1038/nature03868
    • Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature (2005) 436:740-4. doi:10.1038/nature03868
    • (2005) Nature , vol.436 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3    Norman, J.4    Cooch, N.5    Nishikura, K.6
  • 20
    • 0035155389 scopus 로고    scopus 로고
    • The RNase III family: a conserved structure and expanding functions in eukaryotic dsRNA metabolism
    • Lamontagne B, Larose S, Boulanger J, Elela SA. The RNase III family: a conserved structure and expanding functions in eukaryotic dsRNA metabolism. Curr Issues Mol Biol (2001) 3:71-8.
    • (2001) Curr Issues Mol Biol , vol.3 , pp. 71-78
    • Lamontagne, B.1    Larose, S.2    Boulanger, J.3    Elela, S.A.4
  • 21
    • 84863624496 scopus 로고    scopus 로고
    • Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8
    • doi:10.1371/journal.pone.0039688
    • Senturia R, Laganowsky A, Barr I, Scheidemantle BD, Guo F. Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8. PLoS One (2012) 7:e39688. doi:10.1371/journal.pone.0039688
    • (2012) PLoS One , vol.7
    • Senturia, R.1    Laganowsky, A.2    Barr, I.3    Scheidemantle, B.D.4    Guo, F.5
  • 23
    • 84875359231 scopus 로고    scopus 로고
    • Mammalian microRNAs: post-transcriptional gene regulation in RNA virus infection and therapeutic applications
    • doi:10.3389/fmicb.2010.00108
    • Tsunetsugu-Yokota Y, Yamamoto T. Mammalian microRNAs: post-transcriptional gene regulation in RNA virus infection and therapeutic applications. Front Microbiol (2010) 1:108. doi:10.3389/fmicb.2010.00108
    • (2010) Front Microbiol , vol.1 , pp. 108
    • Tsunetsugu-Yokota, Y.1    Yamamoto, T.2
  • 24
    • 84880126095 scopus 로고    scopus 로고
    • A miR-SNP of the XPO5 gene is associated with advanced non-small-cell lung cancer
    • doi:10.2147/OTT.S48284
    • Ding C, Li C, Wang H, Li B, Guo Z. A miR-SNP of the XPO5 gene is associated with advanced non-small-cell lung cancer. Onco Targets Ther (2013) 6:877-81. doi:10.2147/OTT.S48284
    • (2013) Onco Targets Ther , vol.6 , pp. 877-881
    • Ding, C.1    Li, C.2    Wang, H.3    Li, B.4    Guo, Z.5
  • 25
    • 77957969004 scopus 로고    scopus 로고
    • MicroRNA biogenesis takes another single hit from microsatellite instability
    • doi:10.1016/j.ccr.2010.10.005
    • Grosshans H, Bussing I. MicroRNA biogenesis takes another single hit from microsatellite instability. Cancer Cell (2010) 18:295-7. doi:10.1016/j.ccr.2010.10.005
    • (2010) Cancer Cell , vol.18 , pp. 295-297
    • Grosshans, H.1    Bussing, I.2
  • 26
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • doi:10.1038/35053110
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature (2001) 409:363-6. doi:10.1038/35053110
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 27
    • 79960185923 scopus 로고    scopus 로고
    • Dicer recognizes the 5' end of RNA for efficient and accurate processing
    • doi:10.1038/nature10198
    • Park JE, Heo I, Tian Y, Simanshu DK, Chang H, Jee D, et al. Dicer recognizes the 5' end of RNA for efficient and accurate processing. Nature (2011) 475:201-5. doi:10.1038/nature10198
    • (2011) Nature , vol.475 , pp. 201-205
    • Park, J.E.1    Heo, I.2    Tian, Y.3    Simanshu, D.K.4    Chang, H.5    Jee, D.6
  • 28
    • 1442360415 scopus 로고    scopus 로고
    • RNase III enzymes and the initiation of gene silencing
    • doi:10.1038/nsmb729
    • Carmell MA, Hannon GJ. RNase III enzymes and the initiation of gene silencing. Nat Struct Mol Biol (2004) 11:214-8. doi:10.1038/nsmb729
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 214-218
    • Carmell, M.A.1    Hannon, G.J.2
  • 29
    • 84857645458 scopus 로고    scopus 로고
    • A forward genetic screen to study mammalian RNA interference: essential role of RNase IIIa domain of Dicer1 in 3' strand cleavage of dsRNA in vivo
    • doi:10.1111/j.1742-4658.2012.08474.x
    • Ohishi K, Nakano T. A forward genetic screen to study mammalian RNA interference: essential role of RNase IIIa domain of Dicer1 in 3' strand cleavage of dsRNA in vivo. FEBS J (2012) 279:832-43. doi:10.1111/j.1742-4658.2012.08474.x
    • (2012) FEBS J , vol.279 , pp. 832-843
    • Ohishi, K.1    Nakano, T.2
  • 30
    • 84861391272 scopus 로고    scopus 로고
    • In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs
    • doi:10.1261/rna.032680.112
    • Gurtan AM, Lu V, Bhutkar A, Sharp PA. In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs. RNA (2012) 18:1116-22. doi:10.1261/rna.032680.112
    • (2012) RNA , vol.18 , pp. 1116-1122
    • Gurtan, A.M.1    Lu, V.2    Bhutkar, A.3    Sharp, P.A.4
  • 31
    • 43549096196 scopus 로고    scopus 로고
    • The argonaute protein family
    • doi:10.1186/gb-2008-9-2-210
    • Hock J, Meister G. The argonaute protein family. Genome Biol (2008) 9:210. doi:10.1186/gb-2008-9-2-210
    • (2008) Genome Biol , vol.9 , pp. 210
    • Hock, J.1    Meister, G.2
  • 32
    • 84863624199 scopus 로고    scopus 로고
    • The structure of human argonaute-2 in complex with miR-20a
    • doi:10.1016/j.cell.2012.05.017
    • Elkayam E, Kuhn CD, Tocilj A, Haase AD, Greene EM, Hannon GJ, et al. The structure of human argonaute-2 in complex with miR-20a. Cell (2012) 150:100-10. doi:10.1016/j.cell.2012.05.017
    • (2012) Cell , vol.150 , pp. 100-110
    • Elkayam, E.1    Kuhn, C.D.2    Tocilj, A.3    Haase, A.D.4    Greene, E.M.5    Hannon, G.J.6
  • 33
    • 77958048308 scopus 로고    scopus 로고
    • RNA interference: a chemist's perspective
    • doi:10.1039/b920362c
    • Gaynor JW, Campbell BJ, Cosstick R. RNA interference: a chemist's perspective. Chem Soc Rev (2010) 39:4169-84. doi:10.1039/b920362c
    • (2010) Chem Soc Rev , vol.39 , pp. 4169-4184
    • Gaynor, J.W.1    Campbell, B.J.2    Cosstick, R.3
  • 34
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of argonaute and its implications for RISC slicer activity
    • doi:10.1126/science.1102514
    • Song JJ, Smith SK, Hannon GJ, Joshua-Tor L. Crystal structure of argonaute and its implications for RISC slicer activity. Science (2004) 305:1434-7. doi:10.1126/science.1102514
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 35
    • 56249145105 scopus 로고    scopus 로고
    • Structure of the guide-strand-containing argonaute silencing complex
    • doi:10.1038/nature07315
    • Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ. Structure of the guide-strand-containing argonaute silencing complex. Nature (2008) 456:209-13. doi:10.1038/nature07315
    • (2008) Nature , vol.456 , pp. 209-213
    • Wang, Y.1    Sheng, G.2    Juranek, S.3    Tuschl, T.4    Patel, D.J.5
  • 36
    • 77954214431 scopus 로고    scopus 로고
    • Crystal structure and ligand binding of the MID domain of a eukaryotic argonaute protein
    • doi:10.1038/embor.2010.81
    • Boland A, Tritschler F, Heimstadt S, Izaurralde E, Weichenrieder O. Crystal structure and ligand binding of the MID domain of a eukaryotic argonaute protein. EMBO Rep (2010) 11:522-7. doi:10.1038/embor.2010.81
    • (2010) EMBO Rep , vol.11 , pp. 522-527
    • Boland, A.1    Tritschler, F.2    Heimstadt, S.3    Izaurralde, E.4    Weichenrieder, O.5
  • 37
    • 66249134258 scopus 로고    scopus 로고
    • Characterization of the TRBP domain required for dicer interaction and function in RNA interference
    • doi:10.1186/1471-2199-10-38
    • Daniels SM, Melendez-Pena CE, Scarborough RJ, Daher A, Christensen HS, El Far M, et al. Characterization of the TRBP domain required for dicer interaction and function in RNA interference. BMC Mol Biol (2009) 10:38. doi:10.1186/1471-2199-10-38
    • (2009) BMC Mol Biol , vol.10 , pp. 38
    • Daniels, S.M.1    Melendez-Pena, C.E.2    Scarborough, R.J.3    Daher, A.4    Christensen, H.S.5    El Far, M.6
  • 38
    • 78650763143 scopus 로고    scopus 로고
    • Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein
    • doi:10.1002/pro.543
    • Yamashita S, Nagata T, Kawazoe M, Takemoto C, Kigawa T, Guntert P, et al. Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein. Protein Sci (2011) 20:118-30. doi:10.1002/pro.543
    • (2011) Protein Sci , vol.20 , pp. 118-130
    • Yamashita, S.1    Nagata, T.2    Kawazoe, M.3    Takemoto, C.4    Kigawa, T.5    Guntert, P.6
  • 39
    • 84865727711 scopus 로고    scopus 로고
    • The multiple functions of TRBP, at the hub of cell responses to viruses, stress, and cancer
    • doi:10.1128/MMBR.00012-12
    • Daniels SM, Gatignol A. The multiple functions of TRBP, at the hub of cell responses to viruses, stress, and cancer. Microbiol Mol Biol Rev (2012) 76:652-66. doi:10.1128/MMBR.00012-12
    • (2012) Microbiol Mol Biol Rev , vol.76 , pp. 652-666
    • Daniels, S.M.1    Gatignol, A.2
  • 40
    • 45849141942 scopus 로고    scopus 로고
    • Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions
    • doi:10.4161/rna.5.2.6069
    • Laraki G, Clerzius G, Daher A, Melendez-Pena C, Daniels S, Gatignol A. Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions. RNA Biol (2008) 5:92-103. doi:10.4161/rna.5.2.6069
    • (2008) RNA Biol , vol.5 , pp. 92-103
    • Laraki, G.1    Clerzius, G.2    Daher, A.3    Melendez-Pena, C.4    Daniels, S.5    Gatignol, A.6
  • 41
    • 84862879743 scopus 로고    scopus 로고
    • Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs
    • doi:10.1038/nn.3139
    • Knuckles P, Vogt MA, Lugert S, Milo M, Chong MM, Hautbergue GM, et al. Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs. Nat Neurosci (2012) 15:962-9. doi:10.1038/nn.3139
    • (2012) Nat Neurosci , vol.15 , pp. 962-969
    • Knuckles, P.1    Vogt, M.A.2    Lugert, S.3    Milo, M.4    Chong, M.M.5    Hautbergue, G.M.6
  • 42
    • 77956278269 scopus 로고    scopus 로고
    • Canonical and alternate functions of the microRNA biogenesis machinery
    • doi:10.1101/gad.1953310
    • Chong MM, Zhang G, Cheloufi S, Neubert TA, Hannon GJ, Littman DR. Canonical and alternate functions of the microRNA biogenesis machinery. Genes Dev (2010) 24:1951-60. doi:10.1101/gad.1953310
    • (2010) Genes Dev , vol.24 , pp. 1951-1960
    • Chong, M.M.1    Zhang, G.2    Cheloufi, S.3    Neubert, T.A.4    Hannon, G.J.5    Littman, D.R.6
  • 43
    • 77955492563 scopus 로고    scopus 로고
    • Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases
    • doi:10.1016/j.molcel.2010.06.001
    • Karginov FV, Cheloufi S, Chong MM, Stark A, Smith AD, Hannon GJ. Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases. Mol Cell (2010) 38:781-8. doi:10.1016/j.molcel.2010.06.001
    • (2010) Mol Cell , vol.38 , pp. 781-788
    • Karginov, F.V.1    Cheloufi, S.2    Chong, M.M.3    Stark, A.4    Smith, A.D.5    Hannon, G.J.6
  • 44
    • 70349187028 scopus 로고    scopus 로고
    • Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8
    • doi:10.1371/journal.pone.0006971
    • Shenoy A, Blelloch R. Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8. PLoS One (2009) 4:e6971. doi:10.1371/journal.pone.0006971
    • (2009) PLoS One , vol.4
    • Shenoy, A.1    Blelloch, R.2
  • 45
    • 84864085621 scopus 로고    scopus 로고
    • The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis
    • doi:10.1074/jbc.M112.362053
    • Wu Q, Song R, Ortogero N, Zheng H, Evanoff R, Small CL, et al. The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis. J Biol Chem (2012) 287:25173-90. doi:10.1074/jbc.M112.362053
    • (2012) J Biol Chem , vol.287 , pp. 25173-25190
    • Wu, Q.1    Song, R.2    Ortogero, N.3    Zheng, H.4    Evanoff, R.5    Small, C.L.6
  • 46
    • 80053380735 scopus 로고    scopus 로고
    • Drosha regulates hMSCs cell cycle progression through a miRNA independent mechanism
    • doi:10.1016/j.biocel.2011.07.005
    • Oskowitz AZ, Penfornis P, Tucker A, Prockop DJ, Pochampally R. Drosha regulates hMSCs cell cycle progression through a miRNA independent mechanism. Int J Biochem Cell Biol (2011) 43:1563-72. doi:10.1016/j.biocel.2011.07.005
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 1563-1572
    • Oskowitz, A.Z.1    Penfornis, P.2    Tucker, A.3    Prockop, D.J.4    Pochampally, R.5
  • 47
    • 0034711308 scopus 로고    scopus 로고
    • Human RNase III is a 160-kDa protein involved in preribosomal RNA processing
    • doi:10.1074/jbc.M005494200
    • Wu H, Xu H, Miraglia LJ, Crooke ST. Human RNase III is a 160-kDa protein involved in preribosomal RNA processing. J Biol Chem (2000) 275:36957-65. doi:10.1074/jbc.M005494200
    • (2000) J Biol Chem , vol.275 , pp. 36957-36965
    • Wu, H.1    Xu, H.2    Miraglia, L.J.3    Crooke, S.T.4
  • 48
    • 79952733634 scopus 로고    scopus 로고
    • Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex
    • doi:10.1073/pnas.1101219108
    • Fenelon K, Mukai J, Xu B, Hsu PK, Drew LJ, Karayiorgou M, et al. Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex. Proc Natl Acad Sci U S A (2011) 108:4447-52. doi:10.1073/pnas.1101219108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4447-4452
    • Fenelon, K.1    Mukai, J.2    Xu, B.3    Hsu, P.K.4    Drew, L.J.5    Karayiorgou, M.6
  • 49
    • 43949124669 scopus 로고    scopus 로고
    • Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
    • doi:10.1038/ng.138
    • Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, et al. Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet (2008) 40:751-60. doi:10.1038/ng.138
    • (2008) Nat Genet , vol.40 , pp. 751-760
    • Stark, K.L.1    Xu, B.2    Bagchi, A.3    Lai, W.S.4    Liu, H.5    Hsu, R.6
  • 50
    • 84855426004 scopus 로고    scopus 로고
    • Dgcr8 controls neural crest cells survival in cardiovascular development
    • doi:10.1016/j.ydbio.2011.11.008
    • Chapnik E, Sasson V, Blelloch R, Hornstein E. Dgcr8 controls neural crest cells survival in cardiovascular development. Dev Biol (2012) 362:50-6. doi:10.1016/j.ydbio.2011.11.008
    • (2012) Dev Biol , vol.362 , pp. 50-56
    • Chapnik, E.1    Sasson, V.2    Blelloch, R.3    Hornstein, E.4
  • 51
    • 84861741154 scopus 로고    scopus 로고
    • DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice
    • doi:10.1074/jbc.M112.351791
    • Chen Z, Wu J, Yang C, Fan P, Balazs L, Jiao Y, et al. DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice. J Biol Chem (2012) 287:19018-28. doi:10.1074/jbc.M112.351791
    • (2012) J Biol Chem , vol.287 , pp. 19018-19028
    • Chen, Z.1    Wu, J.2    Yang, C.3    Fan, P.4    Balazs, L.5    Jiao, Y.6
  • 52
    • 84867439905 scopus 로고    scopus 로고
    • Dicer is essential for neuronal polarity
    • doi:10.1016/j.ijdevneu.2012.08.002
    • Li Z, He X, Feng J. Dicer is essential for neuronal polarity. Int J Dev Neurosci (2012) 30:607-11. doi:10.1016/j.ijdevneu.2012.08.002
    • (2012) Int J Dev Neurosci , vol.30 , pp. 607-611
    • Li, Z.1    He, X.2    Feng, J.3
  • 53
    • 84876530204 scopus 로고    scopus 로고
    • Dicer1 is required to repress neuronal fate during endocrine cell maturation
    • doi:10.2337/db12-0841
    • Kanji MS, Martin MG, Bhushan A. Dicer1 is required to repress neuronal fate during endocrine cell maturation. Diabetes (2013) 62:1602-11. doi:10.2337/db12-0841
    • (2013) Diabetes , vol.62 , pp. 1602-1611
    • Kanji, M.S.1    Martin, M.G.2    Bhushan, A.3
  • 54
    • 43749120042 scopus 로고    scopus 로고
    • Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus
    • doi:10.1523/JNEUROSCI.4815-07.2008
    • Davis TH, Cuellar TL, Koch SM, Barker AJ, Harfe BD, McManus MT, et al. Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 28:4322-30. doi:10.1523/JNEUROSCI.4815-07.2008
    • (2008) J Neurosci , vol.28 , pp. 4322-4330
    • Davis, T.H.1    Cuellar, T.L.2    Koch, S.M.3    Barker, A.J.4    Harfe, B.D.5    McManus, M.T.6
  • 55
    • 36248978699 scopus 로고    scopus 로고
    • MicroRNA expression is required for pancreatic islet cell genesis in the mouse
    • doi:10.2337/db07-0175
    • Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS. MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes (2007) 56:2938-45. doi:10.2337/db07-0175
    • (2007) Diabetes , vol.56 , pp. 2938-2945
    • Lynn, F.C.1    Skewes-Cox, P.2    Kosaka, Y.3    McManus, M.T.4    Harfe, B.D.5    German, M.S.6
  • 56
    • 62649123872 scopus 로고    scopus 로고
    • Dicer is required for maintaining adult pancreas
    • doi:10.1371/journal.pone.0004212
    • Morita S, Hara A, Kojima I, Horii T, Kimura M, Kitamura T, et al. Dicer is required for maintaining adult pancreas. PLoS One (2009) 4:e4212. doi:10.1371/journal.pone.0004212
    • (2009) PLoS One , vol.4
    • Morita, S.1    Hara, A.2    Kojima, I.3    Horii, T.4    Kimura, M.5    Kitamura, T.6
  • 57
    • 84867028085 scopus 로고    scopus 로고
    • Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism
    • doi:10.1155/2012/470302
    • Mandelbaum AD, Melkman-Zehavi T, Oren R, Kredo-Russo S, Nir T, Dor Y, et al. Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism. Exp Diabetes Res (2012) 2012:470302. doi:10.1155/2012/470302
    • (2012) Exp Diabetes Res , vol.2012 , pp. 470302
    • Mandelbaum, A.D.1    Melkman-Zehavi, T.2    Oren, R.3    Kredo-Russo, S.4    Nir, T.5    Dor, Y.6
  • 58
    • 84455161954 scopus 로고    scopus 로고
    • Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus
    • doi:10.1371/journal.pone.0029166
    • Kalis M, Bolmeson C, Esguerra JL, Gupta S, Edlund A, Tormo-Badia N, et al. Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus. PLoS One (2011) 6:e29166. doi:10.1371/journal.pone.0029166
    • (2011) PLoS One , vol.6
    • Kalis, M.1    Bolmeson, C.2    Esguerra, J.L.3    Gupta, S.4    Edlund, A.5    Tormo-Badia, N.6
  • 59
    • 84867126724 scopus 로고    scopus 로고
    • Deregulated sex chromosome gene expression with male germ cell-specific loss of Dicer1
    • doi:10.1371/journal.pone.0046359
    • Greenlee AR, Shiao MS, Snyder E, Buaas FW, Gu T, Stearns TM, et al. Deregulated sex chromosome gene expression with male germ cell-specific loss of Dicer1. PLoS One (2012) 7:e46359. doi:10.1371/journal.pone.0046359
    • (2012) PLoS One , vol.7
    • Greenlee, A.R.1    Shiao, M.S.2    Snyder, E.3    Buaas, F.W.4    Gu, T.5    Stearns, T.M.6
  • 60
    • 84875431073 scopus 로고    scopus 로고
    • Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks
    • doi:10.4049/jimmunol.1200957
    • Brady BL, Rupp LJ, Bassing CH. Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks. J Immunol (2013) 190:3256-66. doi:10.4049/jimmunol.1200957
    • (2013) J Immunol , vol.190 , pp. 3256-3266
    • Brady, B.L.1    Rupp, L.J.2    Bassing, C.H.3
  • 61
    • 78650306521 scopus 로고    scopus 로고
    • Small RNA sorting: matchmaking for argonautes
    • doi:10.1038/nrg2916
    • Czech B, Hannon GJ. Small RNA sorting: matchmaking for argonautes. Nat Rev Genet (2011) 12:19-31. doi:10.1038/nrg2916
    • (2011) Nat Rev Genet , vol.12 , pp. 19-31
    • Czech, B.1    Hannon, G.J.2
  • 62
    • 34547955952 scopus 로고    scopus 로고
    • A slicer-independent role for argonaute 2 in hematopoiesis and the microRNA pathway
    • doi:10.1101/gad.1565607
    • O'Carroll D, Mecklenbrauker I, Das PP, Santana A, Koenig U, Enright AJ, et al. A slicer-independent role for argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev (2007) 21:1999-2004. doi:10.1101/gad.1565607
    • (2007) Genes Dev , vol.21 , pp. 1999-2004
    • O'Carroll, D.1    Mecklenbrauker, I.2    Das, P.P.3    Santana, A.4    Koenig, U.5    Enright, A.J.6
  • 63
    • 84871959206 scopus 로고    scopus 로고
    • Long-lived microRNA-argonaute complexes in quiescent cells can be activated to regulate mitogenic responses
    • doi:10.1073/pnas.1219958110
    • Olejniczak SH, La Rocca G, Gruber JJ, Thompson CB. Long-lived microRNA-argonaute complexes in quiescent cells can be activated to regulate mitogenic responses. Proc Natl Acad Sci U S A (2013) 110:157-62. doi:10.1073/pnas.1219958110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 157-162
    • Olejniczak, S.H.1    La Rocca, G.2    Gruber, J.J.3    Thompson, C.B.4
  • 64
    • 77956252381 scopus 로고    scopus 로고
    • Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction
    • doi:10.1084/jem.20100451
    • Schaefer A, Im HI, Veno MT, Fowler CD, Min A, Intrator A, et al. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. J Exp Med (2010) 207:1843-51. doi:10.1084/jem.20100451
    • (2010) J Exp Med , vol.207 , pp. 1843-1851
    • Schaefer, A.1    Im, H.I.2    Veno, M.T.3    Fowler, C.D.4    Min, A.5    Intrator, A.6
  • 65
    • 84862905076 scopus 로고    scopus 로고
    • Argonaute2 regulation for K+ channel-mediated human adipose tissue-derived stromal cells self-renewal and survival in nucleus
    • doi:10.1089/scd.2011.0388
    • Kim BS, Im YB, Jung SJ, Park CH, Kang SK. Argonaute2 regulation for K+ channel-mediated human adipose tissue-derived stromal cells self-renewal and survival in nucleus. Stem Cells Dev (2012) 21:1736-48. doi:10.1089/scd.2011.0388
    • (2012) Stem Cells Dev , vol.21 , pp. 1736-1748
    • Kim, B.S.1    Im, Y.B.2    Jung, S.J.3    Park, C.H.4    Kang, S.K.5
  • 66
    • 84878108145 scopus 로고    scopus 로고
    • EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2
    • doi:10.1038/nature12080
    • Shen J, Xia W, Khotskaya YB, Huo L, Nakanishi K, Lim SO, et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature (2013) 497:383-7. doi:10.1038/nature12080
    • (2013) Nature , vol.497 , pp. 383-387
    • Shen, J.1    Xia, W.2    Khotskaya, Y.B.3    Huo, L.4    Nakanishi, K.5    Lim, S.O.6
  • 67
    • 84876244055 scopus 로고    scopus 로고
    • RNA-induced silencing complex (RISC) proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators
    • doi:10.1073/pnas.1301620110
    • Redfern AD, Colley SM, Beveridge DJ, Ikeda N, Epis MR, Li X, et al. RNA-induced silencing complex (RISC) proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators. Proc Natl Acad Sci U S A (2013) 110:6536-41. doi:10.1073/pnas.1301620110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 6536-6541
    • Redfern, A.D.1    Colley, S.M.2    Beveridge, D.J.3    Ikeda, N.4    Epis, M.R.5    Li, X.6
  • 68
    • 81255164734 scopus 로고    scopus 로고
    • The cellular TAR RNA binding protein, TRBP, promotes HIV-1 replication primarily by inhibiting the activation of double-stranded RNA-dependent kinase PKR
    • doi:10.1128/JVI.05240-11
    • Sanghvi VR, Steel LF. The cellular TAR RNA binding protein, TRBP, promotes HIV-1 replication primarily by inhibiting the activation of double-stranded RNA-dependent kinase PKR. J Virol (2011) 85:12614-21. doi:10.1128/JVI.05240-11
    • (2011) J Virol , vol.85 , pp. 12614-12621
    • Sanghvi, V.R.1    Steel, L.F.2
  • 69
    • 84867220979 scopus 로고    scopus 로고
    • Requirements for human Dicer and TRBP in microRNA-122 regulation of HCV translation and RNA abundance
    • doi:10.1016/j.virol.2012.08.039
    • Zhang C, Huys A, Thibault PA, Wilson JA. Requirements for human Dicer and TRBP in microRNA-122 regulation of HCV translation and RNA abundance. Virology (2012) 433:479-88. doi:10.1016/j.virol.2012.08.039
    • (2012) Virology , vol.433 , pp. 479-488
    • Zhang, C.1    Huys, A.2    Thibault, P.A.3    Wilson, J.A.4
  • 70
    • 34248353881 scopus 로고    scopus 로고
    • Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production
    • doi:10.1128/JVI.01511-06
    • Christensen HS, Daher A, Soye KJ, Frankel LB, Alexander MR, Laine S, et al. Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production. J Virol (2007) 81:5121-31. doi:10.1128/JVI.01511-06
    • (2007) J Virol , vol.81 , pp. 5121-5131
    • Christensen, H.S.1    Daher, A.2    Soye, K.J.3    Frankel, L.B.4    Alexander, M.R.5    Laine, S.6
  • 71
    • 78650904206 scopus 로고    scopus 로고
    • Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors
    • doi:10.1016/j.antiviral.2010.11.005
    • Eekels JJ, Geerts D, Jeeninga RE, Berkhout B. Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors. Antiviral Res (2011) 89:43-53. doi:10.1016/j.antiviral.2010.11.005
    • (2011) Antiviral Res , vol.89 , pp. 43-53
    • Eekels, J.J.1    Geerts, D.2    Jeeninga, R.E.3    Berkhout, B.4
  • 72
    • 34547115237 scopus 로고    scopus 로고
    • Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA
    • doi:10.1074/jbc.M611768200
    • Kok KH, Ng MH, Ching YP, Jin DY. Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. J Biol Chem (2007) 282:17649-57. doi:10.1074/jbc.M611768200
    • (2007) J Biol Chem , vol.282 , pp. 17649-17657
    • Kok, K.H.1    Ng, M.H.2    Ching, Y.P.3    Jin, D.Y.4
  • 73
    • 58149463628 scopus 로고    scopus 로고
    • TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress
    • doi:10.1128/MCB.01030-08
    • Daher A, Laraki G, Singh M, Melendez-Pena CE, Bannwarth S, Peters AH, et al. TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress. Mol Cell Biol (2009) 29:254-65. doi:10.1128/MCB.01030-08
    • (2009) Mol Cell Biol , vol.29 , pp. 254-265
    • Daher, A.1    Laraki, G.2    Singh, M.3    Melendez-Pena, C.E.4    Bannwarth, S.5    Peters, A.H.6
  • 74
    • 79952717616 scopus 로고    scopus 로고
    • Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
    • doi:10.1073/pnas.1014720108
    • Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc Natl Acad Sci U S A (2011) 108:4394-9. doi:10.1073/pnas.1014720108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4394-4399
    • Melo, S.1    Villanueva, A.2    Moutinho, C.3    Davalos, V.4    Spizzo, R.5    Ivan, C.6
  • 75
    • 0037112790 scopus 로고    scopus 로고
    • Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm
    • doi:10.1093/emboj/cdf613
    • Bohnsack MT, Regener K, Schwappach B, Saffrich R, Paraskeva E, Hartmann E, et al. Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 21:6205-15. doi:10.1093/emboj/cdf613
    • (2002) EMBO J , vol.21 , pp. 6205-6215
    • Bohnsack, M.T.1    Regener, K.2    Schwappach, B.3    Saffrich, R.4    Paraskeva, E.5    Hartmann, E.6
  • 76
    • 79952361320 scopus 로고    scopus 로고
    • Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels
    • doi:10.1038/nsmb.1987
    • Bennasser Y, Chable-Bessia C, Triboulet R, Gibbings D, Gwizdek C, Dargemont C, et al. Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels. Nat Struct Mol Biol (2011) 18:323-7. doi:10.1038/nsmb.1987
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 323-327
    • Bennasser, Y.1    Chable-Bessia, C.2    Triboulet, R.3    Gibbings, D.4    Gwizdek, C.5    Dargemont, C.6
  • 77
    • 84875450599 scopus 로고    scopus 로고
    • Global microRNA elevation by inducible Exportin 5 regulates cell cycle entry
    • doi:10.1261/rna.036608.112
    • Iwasaki YW, Kiga K, Kayo H, Fukuda-Yuzawa Y, Weise J, Inada T, et al. Global microRNA elevation by inducible Exportin 5 regulates cell cycle entry. RNA (2013) 19:490-7. doi:10.1261/rna.036608.112
    • (2013) RNA , vol.19 , pp. 490-497
    • Iwasaki, Y.W.1    Kiga, K.2    Kayo, H.3    Fukuda-Yuzawa, Y.4    Weise, J.5    Inada, T.6
  • 78
    • 84881319008 scopus 로고    scopus 로고
    • Nuclear export mediated regulation of microRNAs: potential target for drug intervention
    • doi:10.2174/1389450111314100002
    • Muqbil I, Bao B, Abou-Samra AB, Mohammad RM, Azmi AS. Nuclear export mediated regulation of microRNAs: potential target for drug intervention. Curr Drug Targets (2013) 14:1094-100. doi:10.2174/1389450111314100002
    • (2013) Curr Drug Targets , vol.14 , pp. 1094-1100
    • Muqbil, I.1    Bao, B.2    Abou-Samra, A.B.3    Mohammad, R.M.4    Azmi, A.S.5
  • 79
    • 59449098051 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma
    • doi:10.1158/1078-0432.CCR-08-1199
    • Horikawa Y, Wood CG, Yang H, Zhao H, Ye Y, Gu J, et al. Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. Clin Cancer Res (2008) 14:7956-62. doi:10.1158/1078-0432.CCR-08-1199
    • (2008) Clin Cancer Res , vol.14 , pp. 7956-7962
    • Horikawa, Y.1    Wood, C.G.2    Yang, H.3    Zhao, H.4    Ye, Y.5    Gu, J.6
  • 80
    • 84875740314 scopus 로고    scopus 로고
    • Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
    • doi:10.1126/scisignal.2004088
    • Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal (2013) 6:l1. doi:10.1126/scisignal.2004088
    • (2013) Sci Signal , vol.6
    • Gao, J.1    Aksoy, B.A.2    Dogrusoz, U.3    Dresdner, G.4    Gross, B.5    Sumer, S.O.6
  • 81
    • 84866002291 scopus 로고    scopus 로고
    • The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
    • doi:10.1158/2159-8290.CD-12-0095
    • Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov (2012) 2:401-4. doi:10.1158/2159-8290.CD-12-0095
    • (2012) Cancer Discov , vol.2 , pp. 401-404
    • Cerami, E.1    Gao, J.2    Dogrusoz, U.3    Gross, B.E.4    Sumer, S.O.5    Aksoy, B.A.6
  • 82
    • 77953220804 scopus 로고    scopus 로고
    • Expression levels of the microRNA processing enzymes Drosha and dicer in epithelial skin cancer
    • doi:10.3109/07357901003630918
    • Sand M, Gambichler T, Skrygan M, Sand D, Scola N, Altmeyer P, et al. Expression levels of the microRNA processing enzymes Drosha and dicer in epithelial skin cancer. Cancer Invest (2010) 28:649-53. doi:10.3109/07357901003630918
    • (2010) Cancer Invest , vol.28 , pp. 649-653
    • Sand, M.1    Gambichler, T.2    Skrygan, M.3    Sand, D.4    Scola, N.5    Altmeyer, P.6
  • 83
    • 79959958736 scopus 로고    scopus 로고
    • Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles
    • doi:10.1002/path.2898
    • Muralidhar B, Winder D, Murray M, Palmer R, Barbosa-Morais N, Saini H, et al. Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles. J Pathol (2011) 224:496-507. doi:10.1002/path.2898
    • (2011) J Pathol , vol.224 , pp. 496-507
    • Muralidhar, B.1    Winder, D.2    Murray, M.3    Palmer, R.4    Barbosa-Morais, N.5    Saini, H.6
  • 85
    • 84860337317 scopus 로고    scopus 로고
    • Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues
    • doi:10.1111/j.1365-2559.2012.04192.x
    • Papachristou DJ, Sklirou E, Corradi D, Grassani C, Kontogeorgakos V, Rao UN. Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues. Histopathology (2012) 60:E28-36. doi:10.1111/j.1365-2559.2012.04192.x
    • (2012) Histopathology , vol.60
    • Papachristou, D.J.1    Sklirou, E.2    Corradi, D.3    Grassani, C.4    Kontogeorgakos, V.5    Rao, U.N.6
  • 86
    • 78049231803 scopus 로고    scopus 로고
    • microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma
    • doi:10.1158/0008-5472.CAN-10-0970
    • Lin RJ, Lin YC, Chen J, Kuo HH, Chen YY, Diccianni MB, et al. microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma. Cancer Res (2010) 70:7841-50. doi:10.1158/0008-5472.CAN-10-0970
    • (2010) Cancer Res , vol.70 , pp. 7841-7850
    • Lin, R.J.1    Lin, Y.C.2    Chen, J.3    Kuo, H.H.4    Chen, Y.Y.5    Diccianni, M.B.6
  • 87
    • 80052327447 scopus 로고    scopus 로고
    • Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer
    • doi:10.1007/s13277-011-0179-0
    • Torres A, Torres K, Paszkowski T, Jodlowska-Jedrych B, Radomanski T, Ksiazek A, et al. Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer. Tumour Biol (2011) 32:769-76. doi:10.1007/s13277-011-0179-0
    • (2011) Tumour Biol , vol.32 , pp. 769-776
    • Torres, A.1    Torres, K.2    Paszkowski, T.3    Jodlowska-Jedrych, B.4    Radomanski, T.5    Ksiazek, A.6
  • 88
    • 84857039832 scopus 로고    scopus 로고
    • The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma
    • doi:10.1007/s00432-011-1058-1
    • Guo X, Liao Q, Chen P, Li X, Xiong W, Ma J, et al. The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma. J Cancer Res Clin Oncol (2012) 138:49-56. doi:10.1007/s00432-011-1058-1
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 49-56
    • Guo, X.1    Liao, Q.2    Chen, P.3    Li, X.4    Xiong, W.5    Ma, J.6
  • 89
    • 78650420261 scopus 로고    scopus 로고
    • Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer
    • doi:10.1016/j.ejca.2010.08.007
    • Dedes KJ, Natrajan R, Lambros MB, Geyer FC, Lopez-Garcia MA, Savage K, et al. Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer. Eur J Cancer (2011) 47:138-50. doi:10.1016/j.ejca.2010.08.007
    • (2011) Eur J Cancer , vol.47 , pp. 138-150
    • Dedes, K.J.1    Natrajan, R.2    Lambros, M.B.3    Geyer, F.C.4    Lopez-Garcia, M.A.5    Savage, K.6
  • 90
    • 84863831926 scopus 로고    scopus 로고
    • Immunohistochemical study of Dicer and Drosha expression in the benign and malignant lesions of gallbladder and their clinicopathological significances
    • doi:10.1016/j.prp.2012.05.001
    • Shu GS, Yang ZL, Liu DC. Immunohistochemical study of Dicer and Drosha expression in the benign and malignant lesions of gallbladder and their clinicopathological significances. Pathol Res Pract (2012) 208:392-7. doi:10.1016/j.prp.2012.05.001
    • (2012) Pathol Res Pract , vol.208 , pp. 392-397
    • Shu, G.S.1    Yang, Z.L.2    Liu, D.C.3
  • 91
    • 84905109222 scopus 로고    scopus 로고
    • An essential microRNA maturing microprocessor complex component DGCR8 is up-regulated in colorectal carcinomas
    • doi:10.1007/s10238-013-0243-8.
    • Kim B, Lee JH, Park JW, Kwon TK, Baek SK, Hwang I, et al. An essential microRNA maturing microprocessor complex component DGCR8 is up-regulated in colorectal carcinomas. Clin Exp Med (2013). doi:10.1007/s10238-013-0243-8
    • (2013) Clin Exp Med
    • Kim, B.1    Lee, J.H.2    Park, J.W.3    Kwon, T.K.4    Baek, S.K.5    Hwang, I.6
  • 92
    • 84877276198 scopus 로고    scopus 로고
    • Expression levels of microRNA machinery components Drosha, Dicer and DGCR8 in human (AGS, HepG2, and KEYSE-30) cancer cell lines
    • Jafari N, Dogaheh HP, Bohlooli S, Oyong GG, Shirzad Z, Alibeiki F, et al. Expression levels of microRNA machinery components Drosha, Dicer and DGCR8 in human (AGS, HepG2, and KEYSE-30) cancer cell lines. Int J Clin Exp Med (2013) 6:269-74.
    • (2013) Int J Clin Exp Med , vol.6 , pp. 269-274
    • Jafari, N.1    Dogaheh, H.P.2    Bohlooli, S.3    Oyong, G.G.4    Shirzad, Z.5    Alibeiki, F.6
  • 93
    • 84922831283 scopus 로고    scopus 로고
    • Silencing the double-stranded RNA binding protein DGCR8 inhibits ovarian cancer cell proliferation, migration, and invasion
    • doi:10.1007/s11095-013-1219-9.
    • Guo Y, Tian P, Yang C, Liang Z, Li M, Sims M, et al. Silencing the double-stranded RNA binding protein DGCR8 inhibits ovarian cancer cell proliferation, migration, and invasion. Pharm Res (2013). doi:10.1007/s11095-013-1219-9
    • (2013) Pharm Res
    • Guo, Y.1    Tian, P.2    Yang, C.3    Liang, Z.4    Li, M.5    Sims, M.6
  • 94
    • 84863074238 scopus 로고    scopus 로고
    • Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer
    • doi:10.3892/mmr.2011.711
    • Wu D, Tao J, Xu B, Li P, Lu Q, Zhang W. Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer. Mol Med Rep (2012) 5:695-9. doi:10.3892/mmr.2011.711
    • (2012) Mol Med Rep , vol.5 , pp. 695-699
    • Wu, D.1    Tao, J.2    Xu, B.3    Li, P.4    Lu, Q.5    Zhang, W.6
  • 95
    • 84872264446 scopus 로고    scopus 로고
    • Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder
    • doi:10.1002/jso.23214
    • Han Y, Liu Y, Gui Y, Cai Z. Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder. J Surg Oncol (2013) 107:201-5. doi:10.1002/jso.23214
    • (2013) J Surg Oncol , vol.107 , pp. 201-205
    • Han, Y.1    Liu, Y.2    Gui, Y.3    Cai, Z.4
  • 96
    • 79251583208 scopus 로고    scopus 로고
    • Genetic and epigenetic association studies suggest a role of microRNA biogenesis gene exportin-5 (XPO5) in breast tumorigenesis
    • Leaderer D, Hoffman AE, Zheng T, Fu A, Weidhaas J, Paranjape T, et al. Genetic and epigenetic association studies suggest a role of microRNA biogenesis gene exportin-5 (XPO5) in breast tumorigenesis. Int J Mol Epidemiol Genet (2011) 2:9-18.
    • (2011) Int J Mol Epidemiol Genet , vol.2 , pp. 9-18
    • Leaderer, D.1    Hoffman, A.E.2    Zheng, T.3    Fu, A.4    Weidhaas, J.5    Paranjape, T.6
  • 97
    • 77952756515 scopus 로고    scopus 로고
    • Somatic mutations and losses of expression of microRNA regulation-related genes AGO2 and TNRC6A in gastric and colorectal cancers
    • doi:10.1002/path.2683
    • Kim MS, Oh JE, Kim YR, Park SW, Kang MR, Kim SS, et al. Somatic mutations and losses of expression of microRNA regulation-related genes AGO2 and TNRC6A in gastric and colorectal cancers. J Pathol (2010) 221:139-46. doi:10.1002/path.2683
    • (2010) J Pathol , vol.221 , pp. 139-146
    • Kim, M.S.1    Oh, J.E.2    Kim, Y.R.3    Park, S.W.4    Kang, M.R.5    Kim, S.S.6
  • 98
    • 77957940475 scopus 로고    scopus 로고
    • A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells
    • doi:10.1016/j.ccr.2010.09.007
    • Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, et al. A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell (2010) 18:303-15. doi:10.1016/j.ccr.2010.09.007
    • (2010) Cancer Cell , vol.18 , pp. 303-315
    • Melo, S.A.1    Moutinho, C.2    Ropero, S.3    Calin, G.A.4    Rossi, S.5    Spizzo, R.6
  • 99
    • 84863301332 scopus 로고    scopus 로고
    • Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation
    • doi:10.1158/1078-0432.CCR-12-0191
    • de Larrea CF, Navarro A, Tejero R, Tovar N, Diaz T, Cibeira MT, et al. Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation. Clin Cancer Res (2012) 18:3697-704. doi:10.1158/1078-0432.CCR-12-0191
    • (2012) Clin Cancer Res , vol.18 , pp. 3697-3704
    • de Larrea, C.F.1    Navarro, A.2    Tejero, R.3    Tovar, N.4    Diaz, T.5    Cibeira, M.T.6
  • 100
    • 78149416948 scopus 로고    scopus 로고
    • The activity and expression of microRNAs in prostate cancers
    • doi:10.1039/c0mb00100g
    • Fu X, Xue C, Huang Y, Xie Y, Li Y. The activity and expression of microRNAs in prostate cancers. Mol Biosyst (2010) 6:2561-72. doi:10.1039/c0mb00100g
    • (2010) Mol Biosyst , vol.6 , pp. 2561-2572
    • Fu, X.1    Xue, C.2    Huang, Y.3    Xie, Y.4    Li, Y.5
  • 101
    • 20144373433 scopus 로고    scopus 로고
    • Reduced expression of Dicer associated with poor prognosis in lung cancer patients
    • doi:10.1111/j.1349-7006.2005.00015.x
    • Karube Y, Tanaka H, Osada H, Tomida S, Tatematsu Y, Yanagisawa K, et al. Reduced expression of Dicer associated with poor prognosis in lung cancer patients. Cancer Sci (2005) 96:111-5. doi:10.1111/j.1349-7006.2005.00015.x
    • (2005) Cancer Sci , vol.96 , pp. 111-115
    • Karube, Y.1    Tanaka, H.2    Osada, H.3    Tomida, S.4    Tatematsu, Y.5    Yanagisawa, K.6
  • 102
    • 84866549607 scopus 로고    scopus 로고
    • Loss of Dicer expression is associated with breast cancer progression and recurrence
    • doi:10.1007/s10549-012-2169-3
    • Khoshnaw SM, Rakha EA, Abdel-Fatah TM, Nolan CC, Hodi Z, Macmillan DR, et al. Loss of Dicer expression is associated with breast cancer progression and recurrence. Breast Cancer Res Treat (2012) 135:403-13. doi:10.1007/s10549-012-2169-3
    • (2012) Breast Cancer Res Treat , vol.135 , pp. 403-413
    • Khoshnaw, S.M.1    Rakha, E.A.2    Abdel-Fatah, T.M.3    Nolan, C.C.4    Hodi, Z.5    Macmillan, D.R.6
  • 103
    • 84878894068 scopus 로고    scopus 로고
    • Up-regulation of Ago2 expression in gastric carcinoma
    • doi:10.1007/s12032-013-0628-2
    • Zhang J, Fan XS, Wang CX, Liu B, Li Q, Zhou XJ. Up-regulation of Ago2 expression in gastric carcinoma. Med Oncol (2013) 30:628. doi:10.1007/s12032-013-0628-2
    • (2013) Med Oncol , vol.30 , pp. 628
    • Zhang, J.1    Fan, X.S.2    Wang, C.X.3    Liu, B.4    Li, Q.5    Zhou, X.J.6
  • 104
    • 84876712708 scopus 로고    scopus 로고
    • Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma
    • doi:10.1002/hep.26202
    • Cheng N, Li Y, Han ZG. Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma. Hepatology (2013) 57:1906-18. doi:10.1002/hep.26202
    • (2013) Hepatology , vol.57 , pp. 1906-1918
    • Cheng, N.1    Li, Y.2    Han, Z.G.3
  • 105
    • 84872794144 scopus 로고    scopus 로고
    • Overexpression of human argonaute2 inhibits cell and tumor growth
    • doi:10.1016/j.bbagen.2012.11.013
    • Zhang X, Graves P, Zeng Y. Overexpression of human argonaute2 inhibits cell and tumor growth. Biochim Biophys Acta (2013) 1830:2553-61. doi:10.1016/j.bbagen.2012.11.013
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 2553-2561
    • Zhang, X.1    Graves, P.2    Zeng, Y.3
  • 106
    • 84890429103 scopus 로고    scopus 로고
    • Strong reduction of AGO2 expression in melanoma and cellular consequences
    • doi:10.1038/bjc.2013.646
    • Voller D, Reinders J, Meister G, Bosserhoff AK. Strong reduction of AGO2 expression in melanoma and cellular consequences. Br J Cancer (2013) 109:3116-24. doi:10.1038/bjc.2013.646
    • (2013) Br J Cancer , vol.109 , pp. 3116-3124
    • Voller, D.1    Reinders, J.2    Meister, G.3    Bosserhoff, A.K.4
  • 107
    • 84861442401 scopus 로고    scopus 로고
    • Common genetic polymorphisms of microRNA biogenesis pathway genes and breast cancer survival
    • doi:10.1186/1471-2407-12-195
    • Sung H, Jeon S, Lee KM, Han S, Song M, Choi JY, et al. Common genetic polymorphisms of microRNA biogenesis pathway genes and breast cancer survival. BMC Cancer (2012) 12:195. doi:10.1186/1471-2407-12-195
    • (2012) BMC Cancer , vol.12 , pp. 195
    • Sung, H.1    Jeon, S.2    Lee, K.M.3    Han, S.4    Song, M.5    Choi, J.Y.6
  • 108
    • 84887501720 scopus 로고    scopus 로고
    • Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma
    • doi:10.1038/bcj.2013.49
    • Caramuta S, Lee L, Ozata DM, Akcakaya P, Georgii-Hemming P, Xie H, et al. Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma. Blood Cancer J (2013) 3:e152. doi:10.1038/bcj.2013.49
    • (2013) Blood Cancer J , vol.3
    • Caramuta, S.1    Lee, L.2    Ozata, D.M.3    Akcakaya, P.4    Georgii-Hemming, P.5    Xie, H.6
  • 109
    • 84882754577 scopus 로고    scopus 로고
    • Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma
    • doi:10.1530/ERC-13-0098
    • Caramuta S, Lee L, Ozata DM, Akcakaya P, Xie H, Hoog A, et al. Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma. Endocr Relat Cancer (2013) 20:551-64. doi:10.1530/ERC-13-0098
    • (2013) Endocr Relat Cancer , vol.20 , pp. 551-564
    • Caramuta, S.1    Lee, L.2    Ozata, D.M.3    Akcakaya, P.4    Xie, H.5    Hoog, A.6
  • 110
    • 84867898550 scopus 로고    scopus 로고
    • Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer
    • doi:10.1002/mc.20861
    • Sand M, Skrygan M, Georgas D, Arenz C, Gambichler T, Sand D, et al. Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer. Mol Carcinog (2012) 51:916-22. doi:10.1002/mc.20861
    • (2012) Mol Carcinog , vol.51 , pp. 916-922
    • Sand, M.1    Skrygan, M.2    Georgas, D.3    Arenz, C.4    Gambichler, T.5    Sand, D.6
  • 111
    • 33947198771 scopus 로고    scopus 로고
    • Overexpression of Dicer in precursor lesions of lung adenocarcinoma
    • doi:10.1158/0008-5472.CAN-06-3533
    • Chiosea S, Jelezcova E, Chandran U, Luo J, Mantha G, Sobol RW, et al. Overexpression of Dicer in precursor lesions of lung adenocarcinoma. Cancer Res (2007) 67:2345-50. doi:10.1158/0008-5472.CAN-06-3533
    • (2007) Cancer Res , vol.67 , pp. 2345-2350
    • Chiosea, S.1    Jelezcova, E.2    Chandran, U.3    Luo, J.4    Mantha, G.5    Sobol, R.W.6
  • 113
    • 74249095706 scopus 로고    scopus 로고
    • Down-regulation of dicer expression in ovarian cancer tissues
    • doi:10.1016/j.clinbiochem.2009.09.014
    • Pampalakis G, Diamandis EP, Katsaros D, Sotiropoulou G. Down-regulation of dicer expression in ovarian cancer tissues. Clin Biochem (2010) 43:324-7. doi:10.1016/j.clinbiochem.2009.09.014
    • (2010) Clin Biochem , vol.43 , pp. 324-327
    • Pampalakis, G.1    Diamandis, E.P.2    Katsaros, D.3    Sotiropoulou, G.4
  • 114
    • 58049213696 scopus 로고    scopus 로고
    • Dicer, Drosha, and outcomes in patients with ovarian cancer
    • doi:10.1056/NEJMoa0803785
    • Merritt WM, Lin YG, Han LY, Kamat AA, Spannuth WA, Schmandt R, et al. Dicer, Drosha, and outcomes in patients with ovarian cancer. N Engl J Med (2008) 359:2641-50. doi:10.1056/NEJMoa0803785
    • (2008) N Engl J Med , vol.359 , pp. 2641-2650
    • Merritt, W.M.1    Lin, Y.G.2    Han, L.Y.3    Kamat, A.A.4    Spannuth, W.A.5    Schmandt, R.6
  • 115
    • 84862813432 scopus 로고    scopus 로고
    • Downregulated Dicer expression predicts poor prognosis in chronic lymphocytic leukemia
    • doi:10.1111/j.1349-7006.2012.02234.x
    • Zhu DX, Fan L, Lu RN, Fang C, Shen WY, Zou ZJ, et al. Downregulated Dicer expression predicts poor prognosis in chronic lymphocytic leukemia. Cancer Sci (2012) 103:875-81. doi:10.1111/j.1349-7006.2012.02234.x
    • (2012) Cancer Sci , vol.103 , pp. 875-881
    • Zhu, D.X.1    Fan, L.2    Lu, R.N.3    Fang, C.4    Shen, W.Y.5    Zou, Z.J.6
  • 116
    • 84871920699 scopus 로고    scopus 로고
    • Down-regulation of the microRNA processing enzyme Dicer is a prognostic factor in human colorectal cancer
    • doi:10.1111/j.1365-2559.2011.04110.x
    • Faggad A, Kasajima A, Weichert W, Stenzinger A, Elwali NE, Dietel M, et al. Down-regulation of the microRNA processing enzyme Dicer is a prognostic factor in human colorectal cancer. Histopathology (2012) 61:552-61. doi:10.1111/j.1365-2559.2011.04110.x
    • (2012) Histopathology , vol.61 , pp. 552-561
    • Faggad, A.1    Kasajima, A.2    Weichert, W.3    Stenzinger, A.4    Elwali, N.E.5    Dietel, M.6
  • 117
    • 84874416559 scopus 로고    scopus 로고
    • Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer
    • doi:10.3892/ol.2013.1158
    • Kuang Y, Cai J, Li D, Han Q, Cao J, Wang Z. Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer. Oncol Lett (2013) 5:1149-54. doi:10.3892/ol.2013.1158
    • (2013) Oncol Lett , vol.5 , pp. 1149-1154
    • Kuang, Y.1    Cai, J.2    Li, D.3    Han, Q.4    Cao, J.5    Wang, Z.6
  • 118
    • 65649131880 scopus 로고    scopus 로고
    • Alterations in miRNA processing and expression in pleomorphic adenomas of the salivary gland
    • doi:10.1002/ijc.24298
    • Zhang X, Cairns M, Rose B, O'Brien C, Shannon K, Clark J, et al. Alterations in miRNA processing and expression in pleomorphic adenomas of the salivary gland. Int J Cancer (2009) 124:2855-63. doi:10.1002/ijc.24298
    • (2009) Int J Cancer , vol.124 , pp. 2855-2863
    • Zhang, X.1    Cairns, M.2    Rose, B.3    O'Brien, C.4    Shannon, K.5    Clark, J.6
  • 119
    • 67349166196 scopus 로고    scopus 로고
    • Dicer and outcomes in patients with acute myeloid leukemia (AML)
    • doi:10.1016/j.leukres.2009.02.003
    • Martin MG, Payton JE, Link DC. Dicer and outcomes in patients with acute myeloid leukemia (AML). Leuk Res (2009) 33:e127. doi:10.1016/j.leukres.2009.02.003
    • (2009) Leuk Res , vol.33
    • Martin, M.G.1    Payton, J.E.2    Link, D.C.3
  • 120
    • 84902462961 scopus 로고    scopus 로고
    • A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis
    • doi:10.1038/onc.2013.281.
    • Zhang B, Chen H, Zhang L, Dakhova O, Zhang Y, Lewis MT, et al. A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis. Oncogene (2013). doi:10.1038/onc.2013.281
    • (2013) Oncogene
    • Zhang, B.1    Chen, H.2    Zhang, L.3    Dakhova, O.4    Zhang, Y.5    Lewis, M.T.6
  • 121
    • 61349127117 scopus 로고    scopus 로고
    • A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
    • doi:10.1038/ng.317
    • Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, et al. A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet (2009) 41:365-70. doi:10.1038/ng.317
    • (2009) Nat Genet , vol.41 , pp. 365-370
    • Melo, S.A.1    Ropero, S.2    Moutinho, C.3    Aaltonen, L.A.4    Yamamoto, H.5    Calin, G.A.6
  • 122
    • 84876892072 scopus 로고    scopus 로고
    • ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing
    • doi:10.1016/j.cell.2013.03.024
    • Ota H, Sakurai M, Gupta R, Valente L, Wulff BE, Ariyoshi K, et al. ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing. Cell (2013) 153:575-89. doi:10.1016/j.cell.2013.03.024
    • (2013) Cell , vol.153 , pp. 575-589
    • Ota, H.1    Sakurai, M.2    Gupta, R.3    Valente, L.4    Wulff, B.E.5    Ariyoshi, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.