Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation

Clinical Cancer Research

Volumn 18, Issue 13, 2012, Pages 3697-3704

  Fernández De Larrea, Carlos ^a   Navarro, Alfons ^b   Tejero, Rut ^b   Tovar, Natalia ^a   Díaz, Tania ^b   Cibeira, María Teresa ^a   Rosinõl, Laura ^a   Ferrer, Gerardo ^b   Rovira, Montserrat ^a   Rozman, María ^c   Monzó, Mariano ^b   Bladé, Joan ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b Physiology Section   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARMUSTINE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DNA; DOXORUBICIN; EXPORTIN 5; GENOMIC DNA; MELPHALAN; MICRORNA; PREDNISONE; VINCRISTINE;

3' UNTRANSLATED REGION; ADULT; AFF1 GENE; AGED; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BIOGENESIS; CANCER GROWTH; CANCER SURVIVAL; CONTROLLED STUDY; DNA POLYMORPHISM; FAM179B GENE; FEMALE; GENE; GENE TARGETING; HUMAN; KRT81 GENE; MAJOR CLINICAL STUDY; MALE; MIRI96A2 GENE; MULTIPLE MYELOMA; PRIORITY JOURNAL; PROGNOSIS; PROGRESSION FREE SURVIVAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRBP GENE; XPO5 GENE;

3' UNTRANSLATED REGIONS; ADULT; AGED; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE-FREE SURVIVAL; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; KARYOPHERINS; KERATINS, HAIR-SPECIFIC; KERATINS, TYPE II; LYMPHOCYTES; MALE; MICRORNAS; MIDDLE AGED; MULTIPLE MYELOMA; MULTIVARIATE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROTEIN BIOSYNTHESIS; SEQUENCE ANALYSIS, DNA; STEM CELL TRANSPLANTATION; TRANSPLANTATION, AUTOLOGOUS;

EID: 84863301332     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-12-0191     Document Type: Article

References (23)

1. Bladé J, Rosiñol L, Cibeira MT, Rovira M, Carreras E. Hematopoietic stem cell transplantation for multiple myeloma beyond 2010. Blood 2010;115:3655-63.
2. Lahuerta JJ, Mateos MV, Martínez-López J, Rosiñol L, Sureda A, de la Rubia J, et al. Influence of pre- and post-transplantation responses on outcome of patients with multiple myeloma: sequential improvement of response and achievement of complete response are associated with longer survival. J Clin Oncol 2008;26:5775-82.
3. Kumar SK, Rajkumar SV, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK, et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood 2008;111:2516-20.
4. Ludwig H, Bolejack V, Crowley J, Bladé J, Miguel JS, Kyle RA, et al. Survival and years of life lost in different age cohorts of patients with multiple myeloma. J Clin Oncol 2010;28:1599-05.
5. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature 2005;435:834-38. (Pubitemid 40839735)
6. Gutiérrez NC, Sarasquete ME, Misiewicz-Krzeminska I, Delgado M, De Las Rivas J, Ticona FV, et al. Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling. Leukemia 2010;24:629-37.
7. Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006;6:259-69.
8. Ryan BM, Robles AI, Harris CC. Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 2010;10: 389-402.
9. Dumontet C, Landi S, Reiman T, Perry T, Plesa A, Bellini I, et al. Genetic polymorphisms associated with outcome in multiple myeloma patients receiving high-dose melphalan. Bone Marrow Transplant 2010;45: 1316-24.
10. Du J, Huo J, Shi J, Yuan Z, Zhang C, Fu W, et al. Polymorphisms of NF-{kappa}B family genes are associated with development of multiple myeloma and treatment outcome in patients undergoing bortezomib-based regimens. Haematologica 2011;96:729-37.
11. Bladé J, Samson D, Reece D, Apperley J, Björkstrand B, Gahrton G, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol 1998;102:1115-23. (Pubitemid 28435189)
12. Ye Y, Wang KK, Gu J, Yang H, Lin J, Ajani JA, Wu X. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. Cancer Prev Res 2008;1:460-69.
13. Yu Z, Li Z, Jolicoeur N, Zhang L, Fortin Y, Wang E, et al. Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. Nucleic Acids Res 2007;35: 4535-41. (Pubitemid 47244604)
14. Campayo M, Viñolas N, Navarro A, Carcereny E, Casas F, Gel B, et al. Single nucleotide polymorphisms in tobacco metabolism and DNA repair genes and prognosis in resected non-small-cell lung cancer. J Surg Res 2011;167:e5-12.
15. Monzo M, Brunet S, Urbano-Ispizua A, Navarro A, Perea G, Esteve J, et al. Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia. Blood 2006;107: 4871-79. (Pubitemid 43882640)
16. Karantza V. Keratins in health and cancer: more than mere epithelial cell markers. Oncogene 2011;30:127-38.
17. Stacey SN, Sulem P, Masson G, Gudjonsson SA, Thorleifsson G, Jakobsdottir M, et al. New common variants affecting susceptibility to basal cell carcinoma. Nat Genet 2009;41:909-14.
18. Pichiorri F, Suh SS, Ladetto M, Kuehl M, Palumbo T, Drandi D, et al. MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis. Proc Natl Acad Sci USA 2008;105: 12885-90.
19. Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, et al. Initial genome sequencing and analysis of multiple myeloma. Nature 2011;471:467-72.
20. Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol 2005;6:376-85. (Pubitemid 40637855)
21. Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, et al. A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell 2010;18:303-15.
22. Boni V, Zarate R, Villa JC, Bandrés E, Gomez MA, Maiello E, et al. Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan. Pharmacogenomics J 2011;11:429-36.
23. Puente XS, Pinyol M, Quesada V, Conde L, Ordóñez GR, Villamor N, et al. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature 2011;475: 101-5.