Silencing the double-stranded RNA binding protein DGCR8 inhibits ovarian cancer cell proliferation, migration, and invasion

Pharmaceutical Research

Volumn 32, Issue 3, 2015, Pages 769-778

  Guo, Yuqi ^b   Tian, Peng ^a,b   Yang, Chuanhe ^a   Liang, Zhibing ^d   Li, Min ^a,c   Sims, Michelle ^a   Lu, Lu ^a   Zhang, Zhan ^b   Li, Hongwei ^d   Pfeffer, Lawrence M ^a   Yue, Junming ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b ZHENGZHOU UNIVERSITY   (China)

^c SHAANXI UNIVERSITY OF CHINESE MEDICINE   (China)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

DGCR8; miRNA; ovarian cancer

Indexed keywords

BINDING PROTEIN; CISPLATIN; DIGEORGE CRITICAL REGION 8; DOUBLE STRANDED RNA; LENTIVIRUS VECTOR; MICRORNA; MICRORNA 27B; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DGCR8 PROTEIN, HUMAN; MIRN27 MICRORNA, HUMAN; RNA BINDING PROTEIN; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CELL INVASION; CELL INVASION ASSAY; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; ONCOGENE; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR GROWTH; UPREGULATION; ANIMAL; CELL MOTION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; METABOLISM; NONOBESE DIABETIC MOUSE; OVARIAN NEOPLASMS; PATHOLOGY; PROCEDURES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTOR; TRANSGENIC MOUSE; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC THERAPY; HUMANS; MICE, INBRED NOD; MICE, TRANSGENIC; MICRORNAS; NEOPLASM INVASIVENESS; ONCOGENES; OVARIAN NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84922831283     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-013-1219-9     Document Type: Article

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