Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 48, Issue 6, 2013, Pages 781-789

  Bauer, Christopher ^a   Kielian, Tammy ^a   Wyatt, Todd A ^a,b   Romberger, Debra J ^a,b   West, William W ^a   Gleason, Angela M ^a   Poole, Jill A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Veterans Administration   (United States)

Author keywords

IL 1R IL 18R; Lung; MyD88; Organic dust; Toll like receptor

Indexed keywords

CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; ICAM1 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR; MYD88 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TLR9 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL AGGREGATION; CONTROLLED STUDY; CYTOKINE RELEASE; DUST EXPOSURE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NEUTROPHIL CHEMOTAXIS; NICK END LABELING; NONHUMAN; ORGANIC DUST; PROTECTION; PROTEIN EXPRESSION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; WILD TYPE; ANIMAL; BRONCHUS HYPERREACTIVITY; C57BL MOUSE; CELL DIFFERENTIATION; DUST; EXPOSURE; GENETICS; IMMUNOLOGY; INFLAMMATION; LUNG; LUNG FUNCTION TEST; METABOLISM; MOUSE MUTANT; NEUTROPHIL; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BRONCHIAL HYPERREACTIVITY; CELL DIFFERENTIATION; DUST; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATION; INFLAMMATION MEDIATORS; INHALATION EXPOSURE; INTERCELLULAR ADHESION MOLECULE-1; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHIL INFILTRATION; NEUTROPHILS; RECEPTORS, INTERLEUKIN-1; RECEPTORS, INTERLEUKIN-18; RESPIRATORY FUNCTION TESTS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9;

MLCS; MLOWN;

EID: 84881012470     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0479OC     Document Type: Article

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