Systemic inhibition of NF-κB activation protects from silicosis

PLoS ONE

Volumn 4, Issue 5, 2009, Pages

  di Giuseppe, Michelangelo ^a   Gambelli, Federica ^a   Hoyle, Gary W ^b   Lungarella, Giuseppe ^c   Studer, Sean M ^d   Richards, Thomas ^d   Yousem, Sam ^d   McCurry, Ken ^d   Dauber, James ^d   Kaminski, Naftali ^d   Leikauf, George ^a   Ortiz, Luis A ^a,d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c UNIVERSITY OF SIENA   (Italy)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 TERT BUTYLPHENYLSULFONYL) 2 PROPENENITRILE; COLLAGEN; GRANULOCYTE COLONY STIMULATING FACTOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MONOCYTE CHEMOTACTIC PROTEIN 1; SILICON DIOXIDE; STAT1 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; I KAPPA B; MESSENGER RNA; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NITRILE; SULFONE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRONCHIOLITIS OBLITERANS; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; EPITHELIUM CELL; EXPERIMENTAL MODEL; FEMALE; FIBROSING ALVEOLITIS; HUMAN; HUMAN TISSUE; INFLAMMATORY CELL; LUNG GRAFT REJECTION; LUNG NODULE; LUNG TRANSPLANTATION; MACROPHAGE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SILICOSIS; SURVIVAL RATE; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; DOMINANT GENE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LUNG; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROGNOSIS;

MUS MUSCULUS;

ANIMALS; CYTOKINES; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; GENES, DOMINANT; HUMANS; I-KAPPA B PROTEINS; LUNG; LUNG TRANSPLANTATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; NF-KAPPA B; NITRILES; PROGNOSIS; RNA, MESSENGER; SILICON DIOXIDE; SILICOSIS; SULFONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 66249123631     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005689     Document Type: Article

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