메뉴 건너뛰기




Volumn 184, Issue 11, 2011, Pages 1270-1281

Platelet-derived growth factor-producing CD4 + foxp3 +regulatory T lymphocytes promote lung fibrosis

Author keywords

Effector T cells; Fibroblasts; Foxp3; PDGF TGF ; Regulatory T cells

Indexed keywords

CD4 ANTIGEN; COLLAGEN; IMATINIB; INTERLEUKIN 4; PLATELET DERIVED GROWTH FACTOR B; SILICON DIOXIDE; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1;

EID: 82555197056     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201103-0516OC     Document Type: Article
Times cited : (98)

References (50)
  • 1
    • 75949130829 scopus 로고    scopus 로고
    • Strategies for treating idiopathic pulmonary fibrosis
    • du Bois RM. Strategies for treating idiopathic pulmonary fibrosis. Nat Rev Drug Discov 2010;9:129-140.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 129-140
    • Du Bois, R.M.1
  • 2
    • 77952312504 scopus 로고    scopus 로고
    • Update in diffuse parenchymal lung disease 2009
    • Eickelberg O, Selman M. Update in diffuse parenchymal lung disease 2009. Am J Respir Crit Care Med 2010;181:883-888.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 883-888
    • Eickelberg, O.1    Selman, M.2
  • 6
    • 79960381007 scopus 로고    scopus 로고
    • Integrating mechanisms of pulmonary fibrosis
    • Wynn TA. Integrating mechanisms of pulmonary fibrosis. J Exp Med 2011;208:1339-1350.
    • (2011) J Exp Med , vol.208 , pp. 1339-1350
    • Wynn, T.A.1
  • 8
    • 0026506740 scopus 로고
    • Lymphocyte-macrophage alveolitis in non-smoking individuals occupationally exposed to asbestos
    • Rom WN, Travis WD. Lymphocyte-macrophage alveolitis in non-smoking individuals occupationally exposed to asbestos. Chest 1992; 101:779-786.
    • (1992) Chest , vol.101 , pp. 779-786
    • Rom, W.N.1    Travis, W.D.2
  • 10
    • 66049111238 scopus 로고    scopus 로고
    • Regulation of pulmonary inflammation and fibrosis through expression of integrins alphaVbeta3 and alphaVbeta5 on pulmonary T lymphocytes
    • Luzina IG, Todd NW, Nacu N, Lockatell V, Choi J, Hummers LK, Atamas SP. Regulation of pulmonary inflammation and fibrosis through expression of integrins alphaVbeta3 and alphaVbeta5 on pulmonary T lymphocytes. Arthritis Rheum 2009;60:1530-1539.
    • (2009) Arthritis Rheum , vol.60 , pp. 1530-1539
    • Luzina, I.G.1    Todd, N.W.2    Nacu, N.3    Lockatell, V.4    Choi, J.5    Hummers, L.K.6    Atamas, S.P.7
  • 12
    • 30044449492 scopus 로고    scopus 로고
    • 1 production and fibrosis
    • DOI 10.1038/nm1332
    • Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A. IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nat Med 2006;12:99-106. (Pubitemid 43050083)
    • (2006) Nature Medicine , vol.12 , Issue.1 , pp. 99-106
    • Fichtner-Feigl, S.1    Strober, W.2    Kawakami, K.3    Puri, R.K.4    Kitani, A.5
  • 15
    • 0037385330 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1038/ni904
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003;4:330-336. (Pubitemid 36432314)
    • (2003) Nature Immunology , vol.4 , Issue.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 16
    • 65549145814 scopus 로고    scopus 로고
    • Control of regulatory T cell lineage commitment and maintenance
    • Josefowicz SZ, Rudensky A. Control of regulatory T cell lineage commitment and maintenance. Immunity 2009;30:616-625.
    • (2009) Immunity , vol.30 , pp. 616-625
    • Josefowicz, S.Z.1    Rudensky, A.2
  • 17
    • 60649102339 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Pathogenesis, etiology and regulation
    • Wilson MS, Wynn TA. Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol 2009;2:103-121.
    • (2009) Mucosal Immunol , vol.2 , pp. 103-121
    • Wilson, M.S.1    Wynn, T.A.2
  • 18
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor Foxp3
    • DOI 10.1016/j.immuni.2005.01.016
    • Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the fork-head transcription factor foxp3. Immunity 2005;22:329-341. (Pubitemid 40387475)
    • (2005) Immunity , vol.22 , Issue.3 , pp. 329-341
    • Fontenot, J.D.1    Rasmussen, J.P.2    Williams, L.M.3    Dooley, J.L.4    Farr, A.G.5    Rudensky, A.Y.6
  • 21
    • 77952517567 scopus 로고    scopus 로고
    • Imatinib therapy reduces radiation-induced pulmonary mast cell influx and delays lung disease in the mouse
    • Thomas DM, Fox J, Haston CK. Imatinib therapy reduces radiation-induced pulmonary mast cell influx and delays lung disease in the mouse. Int J Radiat Biol 2010;86:436-444.
    • (2010) Int J Radiat Biol , vol.86 , pp. 436-444
    • Thomas, D.M.1    Fox, J.2    Haston, C.K.3
  • 24
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 2001;134:136-151. (Pubitemid 32096342)
    • (2001) Annals of Internal Medicine , vol.134 , Issue.2 , pp. 136-151
    • Selman, M.1    King Jr., T.E.2    Pardo, A.3
  • 25
    • 33947123566 scopus 로고    scopus 로고
    • New developments in the understanding of immunology in silicosis
    • DOI 10.1097/ACI.0b013e32802bf8a5, PII 0013083220070400000009
    • Huaux F. New developments in the understanding of immunology in silicosis. Curr Opin Allergy Clin Immunol 2007;7:168-173. (Pubitemid 46411518)
    • (2007) Current Opinion in Allergy and Clinical Immunology , vol.7 , Issue.2 , pp. 168-173
    • Huaux, F.1
  • 28
    • 0037144530 scopus 로고    scopus 로고
    • Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways
    • Lee CG, Homer RJ, Cohn L, Link H, Jung S, Craft JE, Graham BS, Johnson TR, Elias JA. Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways. J Biol Chem 2002;277:35466-35474.
    • (2002) J Biol Chem , vol.277 , pp. 35466-35474
    • Lee, C.G.1    Homer, R.J.2    Cohn, L.3    Link, H.4    Jung, S.5    Craft, J.E.6    Graham, B.S.7    Johnson, T.R.8    Elias, J.A.9
  • 30
    • 33750335078 scopus 로고    scopus 로고
    • Regulatory T cells dampen pulmonary inflammation and lung injury in an animal model of Pneumocystis pneumonia
    • McKinley L, Logar AJ, McAllister F, Zheng M, Steele C, Kolls JK. Regulatory T cells dampen pulmonary inflammation and lung injury in an animal model of pneumocystis pneumonia. J Immunol 2006;177:6215-6226. (Pubitemid 44628840)
    • (2006) Journal of Immunology , vol.177 , Issue.9 , pp. 6215-6226
    • McKinley, L.1    Logar, A.J.2    McAllister, F.3    Zheng, M.4    Steele, C.5    Kolls, J.K.6
  • 31
    • 33847143728 scopus 로고    scopus 로고
    • Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells
    • DOI 10.1084/jem.20061196
    • Hammad H, Kool M, Soullie T, Narumiya S, Trottein F, Hoogsteden HC, Lambrecht BN. Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J Exp Med 2007;204:357-367. (Pubitemid 46294551)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.2 , pp. 357-367
    • Hammad, H.1    Kool, M.2    Soullie, T.3    Narumiya, S.4    Trottein, F.5    Hoogsteden, H.C.6    Lambrecht, B.N.7
  • 34
    • 34547604820 scopus 로고    scopus 로고
    • Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection
    • DOI 10.1016/j.jhep.2007.03.023, PII S0168827807002012
    • Ward SM, Fox BC, Brown PJ, Worthington J, Fox SB, Chapman RW, Fleming KA, Banham AH, Klenerman P. Quantification and localisation of FOXP31 T lymphocytes and relation to hepatic inflammation during chronic HCV infection. J Hepatol 2007;47:316-324. (Pubitemid 47189607)
    • (2007) Journal of Hepatology , vol.47 , Issue.3 , pp. 316-324
    • Ward, S.M.1    Fox, B.C.2    Brown, P.J.3    Worthington, J.4    Fox, S.B.5    Chapman, R.W.6    Fleming, K.A.7    Banham, A.H.8    Klenerman, P.9
  • 38
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • DOI 10.1016/j.cytogfr.2004.03.006, PII S1359610104000164
    • Bonner JC. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev 2004;15:255-273. (Pubitemid 38781050)
    • (2004) Cytokine and Growth Factor Reviews , vol.15 , Issue.4 , pp. 255-273
    • Bonner, J.C.1
  • 39
    • 25444467151 scopus 로고    scopus 로고
    • Growth factors in idiopathic pulmonary fibrosis: Relative roles
    • Allen JT, Spiteri MA. Growth factors in idiopathic pulmonary fibrosis: relative roles. Respir Res 2002;3:13.
    • (2002) Respir Res , vol.3 , pp. 13
    • Allen, J.T.1    Spiteri, M.A.2
  • 42
    • 78751694228 scopus 로고    scopus 로고
    • An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor beta receptor
    • Hoyles RK, Derrett-Smith EC, Khan K, Shiwen X, Howat SL, Wells AU, Abraham DJ, Denton CP. An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor beta receptor. Am J Respir Crit Care Med 2011;183:249-261.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 249-261
    • Hoyles, R.K.1    Derrett-Smith, E.C.2    Khan, K.3    Shiwen, X.4    Howat, S.L.5    Wells, A.U.6    Abraham, D.J.7    Denton, C.P.8
  • 43
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-788. (Pubitemid 29152623)
    • (1999) Journal of Clinical Investigation , vol.103 , Issue.6 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8
  • 44
    • 0242494298 scopus 로고    scopus 로고
    • Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis
    • Huaux F, Liu T, McGarry B, Ullenbruch M, Xing Z, Phan SH. Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis. J Immunol 2003;171:5470-5481. (Pubitemid 37432836)
    • (2003) Journal of Immunology , vol.171 , Issue.10 , pp. 5470-5481
    • Huaux, F.1    Liu, T.2    McGarry, B.3    Ullenbruch, M.4    Xing, Z.5    Phan, S.H.6
  • 45
    • 0035815696 scopus 로고    scopus 로고
    • Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta: Integration at the level of p300/CBP transcriptional coactivators
    • DOI 10.1074/jbc.M004709200
    • Ghosh AK, Yuan W, Mori Y, Chen S, Varga J. Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta: integration at the level of p300/CBP transcriptional coactivators. J Biol Chem 2001;276:11041-11048. (Pubitemid 38089285)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.14 , pp. 11041-11048
    • Ghosh, A.K.1    Yuan, W.2    Mori, Y.3    Chen, S.-J.4    Varga, J.5
  • 46
    • 0029966632 scopus 로고    scopus 로고
    • Interleukin-4 and interferon-gamma discordantly regulate collagen biosynthesis by functionally distinct lung fibroblast subsets
    • DOI 10.1002/(SICI)1097-4652(199605)167:2<290::AID-JCP13>3.0.CO;2-C
    • Sempowski GD, Derdak S, Phipps RP. Interleukin-4 and interferon-gamma discordantly regulate collagen biosynthesis by functionally distinct lung fibroblast subsets. J Cell Physiol 1996;167:290-296. (Pubitemid 26145862)
    • (1996) Journal of Cellular Physiology , vol.167 , Issue.2 , pp. 290-296
    • Sempowski, G.D.1    Derdak, S.2    Phipps, R.P.3
  • 48
    • 0036447487 scopus 로고    scopus 로고
    • Role of interferon-gamma in the development of murine bronchus-associated lymphoid tissues induced by silica in vivo
    • DOI 10.1006/taap.2002.9511
    • Desaki M, Sugawara I, Iwakura Y, Yamamoto K, Takizawa H. Role of interferon-gamma in the development of murine bronchus-associated lymphoid tissues induced by silica in vivo. Toxicol Appl Pharmacol 2002;185:1-7. (Pubitemid 35425691)
    • (2002) Toxicology and Applied Pharmacology , vol.185 , Issue.1 , pp. 1-7
    • Desaki, M.1    Sugawara, I.2    Iwakura, Y.3    Yamamoto, K.4    Takizawa, H.5
  • 49
    • 43349091452 scopus 로고    scopus 로고
    • The IL-4Ralpha pathway in macrophages and its potential role in silica-induced pulmonary fibrosis
    • DOI 10.1189/jlb.0807533
    • Migliaccio CT, Buford MC, Jessop F, Holian A. The IL-4Ralpha pathway in macrophages and its potential role in silica-induced pulmonary fibrosis. J Leukoc Biol 2008;83:630-639. (Pubitemid 351966873)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.3 , pp. 630-639
    • Migliaccio, C.T.1    Buford, M.C.2    Jessop, F.3    Holian, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.