Autoactivation of the MDM2 E3 ligase by intramolecular interaction

Molecular and Cellular Biology

Volumn 34, Issue 15, 2014, Pages 2800-2810

  Cheng, Qian ^a   Song, Tanjing ^a   Chen, Lihong ^a   Chen, Jiandong ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CASPASE 3; PROTEIN MDM2; PROTEIN P53; UBIQUITIN PROTEIN LIGASE E3;

ACIDITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; RING FINGER MOTIF; SIGNAL TRANSDUCTION; UBIQUITINATION;

BINDING SITES; CATALYSIS; CELL LINE; DNA DAMAGE; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES;

EID: 84904307595     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00246-14     Document Type: Article

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