MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output

EMBO Journal

Volumn 29, Issue 15, 2010, Pages 2538-2552

  Chen, Lihong ^a   Li, Zhenyu ^a   Zwolinska, Aleksandra K ^b   Smith, Matthew A ^a   Cross, Brittany ^a   Koomen, John ^a   Yuan, Zhi Min ^c   Jenuwein, Thomas ^d   Marine, Jean Christophe ^b   Wright, Kenneth L ^a   Chen, Jiandong ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c Mays Cancer Center at UT Health San Antonio   (United States)

^d MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

EHMT1; histone methyltransferases; MDM2; p53; SUV39H1

Indexed keywords

HISTONE H3; HISTONE METHYLTRANSFERASE; METHYLTRANSFERASE; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P53;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; STRESS;

ANIMALS; CELLS, CULTURED; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; LYSINE; METHYLATION; METHYLTRANSFERASES; MICE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-MDM2; REPRESSOR PROTEINS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77955415488     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.140     Document Type: Article

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