Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

Nature

Volumn 489, Issue 7414, 2012, Pages 115-120

  Plechanovov, Anna ^a   Jaffray, Ellis G ^a   Tatham, Michael H ^a   Naismith, James H ^b   Hay, Ronald T ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE; RING E3 LIGASE; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; MOLECULAR ANALYSIS; PEPTIDE; PROTEIN; RODENT; SUBSTRATE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

ANIMALS; BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROLYSIS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTATION; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; TRANSCRIPTION FACTORS; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; ZINC FINGERS;

RATTUS;

EID: 84865781586     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11376     Document Type: Article

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