Hedgehog induces formation of PKA-smoothened complexes to promote smoothened phosphorylation and pathway activation

Science Signaling

Volumn 7, Issue 332, 2014, Pages

  Li, Shuang ^a   Ma, Guoqiang ^a   Wang, Bing ^a   Jiang, Jin ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COSTAL2 PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOUBLE STRANDED RNA; PROTEIN; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; CI PROTEIN, DROSOPHILA; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; G PROTEIN COUPLED RECEPTOR; HEDGEHOG PROTEIN, DROSOPHILA; SMOOTHENED PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR;

5' UNTRANSLATED REGION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOSENSOR; CARBOXY TERMINAL SEQUENCE; CELL CLONING; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; DROSOPHILA MELANOGASTER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE MUTATION; GENE SILENCING; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; JUXTAMEMBRANE REGION; MYRISTYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE; ANIMAL; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN MULTIMERIZATION;

ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HEDGEHOG PROTEINS; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84903779617     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005414     Document Type: Article

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