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We are grateful to G. Struhl and P. Simpson for insightful discussions and help with the manuscript. We also thank S. Gonzalez, I. Guerrero, P. Lawrence, and E. Sanchez-Herrero for their comments on the manuscript; P. Geyer for sending the yellow cDNAs; P. Simpson for sending pnr mutations; R. Gonzalez for preparing flies and embryos; S. Shah for help in the initial stages of the work; A. Losadafor teaching us about hybridization to polytene chromosomes; and D. Ferrés-Marco for giving us the im mutations. Supported by grants from the Dirección General de Investigación Cientifica y Técnica and the Human Frontier Science Program Organization (RG-372/94). The Centro de Biologia Molecular also receives an institutional grant from the Fundación Ramón Areces.
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