Reading the hedgehog morphogen gradient by measuring the ratio of bound to unbound patched protein

Nature

Volumn 431, Issue 7004, 2004, Pages 76-80

  Casali, Andreu ^a   Struhl, Gary ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; DPP PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; G PROTEIN COUPLED RECEPTOR; HEDGEHOG PROTEIN, DROSOPHILA; KNOT PROTEIN, DROSOPHILA; LIGAND; MEMBRANE PROTEIN; PTC PROTEIN, DROSOPHILA; SMOOTHENED PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR; MORPHOGEN; PROTEIN; PROTEIN PATCHED; RECEPTOR; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; METABOLISM; MUTATION; PRENATAL DEVELOPMENT; PROTEIN BINDING; SIGNAL TRANSDUCTION; TRANSGENE; TRANSGENIC ANIMAL; CONCENTRATION (PARAMETERS); GENE EXPRESSION; GENE TARGETING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; TRANSDUCER;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GENOTYPE; LIGANDS; MEMBRANE PROTEINS; MUTATION; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSGENES;

CELLS; GENES; MATHEMATICAL MODELS; MOLECULAR STRUCTURE;

CELL PERCEPTION; GENE EXPRESSION; MORPHOGENS;

PROTEINS;

BIOLOGY; CYTOLOGY;

ERINACEIDAE;

EID: 4544331178     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02835     Document Type: Letter

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