-
1
-
-
0038162585
-
Decline in the AIDS and death rates in the EuroSIDA study: An observational study
-
DOI 10.1016/S0140-6736(03)13802-0
-
Mocroft A, Ledergerber B, Katlama C, Kirk O, Reiss P, d'Arminio Monforte A, et al. Decline in the AIDS and death rates in the EuroSIDA study: an observational study. Lancet. 2003;362(9377):22-9. (Pubitemid 36835816)
-
(2003)
Lancet
, vol.362
, Issue.9377
, pp. 22-29
-
-
Mocroft, A.1
Ledergerber, B.2
Katlama, C.3
Kirk, O.4
Reiss, P.5
D'Arminio, M.A.6
Knysz, B.7
Dietrich, M.8
Phillips, A.N.9
Lundgren, J.D.10
-
2
-
-
73649107271
-
The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals
-
Ray M, Logan R, Sterne JA, Hernandez-Diaz S, Robins JM, Sabin C, et al. The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals. AIDS. 2010;24(1):123-37.
-
(2010)
AIDS
, vol.24
, Issue.1
, pp. 123-137
-
-
Ray, M.1
Logan, R.2
Sterne, J.A.3
Hernandez-Diaz, S.4
Robins, J.M.5
Sabin, C.6
-
3
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
-
DOI 10.1056/NEJM199803263381301
-
Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998;338(13):853-60. (Pubitemid 28135961)
-
(1998)
New England Journal of Medicine
, vol.338
, Issue.13
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
Loveless, M.O.4
Fuhrer, J.5
Satten, G.A.6
Aschman, D.J.7
Holmberg, S.D.8
-
4
-
-
84903748113
-
-
Accessed 20 Dec 2013
-
UNAIDS global report. http://www.unaids.org/en/media/unaids/ contentassets/documents/epidemiology//gr/UNAIDS-Global-Report-en.pdf. Accessed 20 Dec 2013.
-
UNAIDS Global Report
-
-
-
5
-
-
80051633217
-
Prevention of HIV-1 infection with early antiretroviral therapy
-
Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493-505.
-
(2011)
N Engl J Med
, vol.365
, Issue.6
, pp. 493-505
-
-
Cohen, M.S.1
Chen, Y.Q.2
McCauley, M.3
Gamble, T.4
Hosseinipour, M.C.5
Kumarasamy, N.6
-
6
-
-
84864527306
-
Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana
-
Thigpen MC, Kebaabetswe PM, Paxton LA, Smith DK, Rose CE, Segolodi TM, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med. 2012;367(5):423-34.
-
(2012)
N Engl J Med
, vol.367
, Issue.5
, pp. 423-434
-
-
Thigpen, M.C.1
Kebaabetswe, P.M.2
Paxton, L.A.3
Smith, D.K.4
Rose, C.E.5
Segolodi, T.M.6
-
7
-
-
84864507852
-
Preexposure prophylaxis for HIV infection among African women
-
Van Damme L, Corneli A, Ahmed K, Agot K, Lombaard J, Kapiga S, et al. Preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2012;367(5):411-22.
-
(2012)
N Engl J Med
, vol.367
, Issue.5
, pp. 411-422
-
-
Van Damme, L.1
Corneli, A.2
Ahmed, K.3
Agot, K.4
Lombaard, J.5
Kapiga, S.6
-
8
-
-
77955930318
-
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
-
Abdool Karim Q, Abdool Karim SS, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329(5996):1168-74.
-
(2010)
Science
, vol.329
, Issue.5996
, pp. 1168-1174
-
-
Abdool Karim, Q.1
Abdool Karim, S.S.2
Frohlich, J.A.3
Grobler, A.C.4
Baxter, C.5
Mansoor, L.E.6
-
9
-
-
84864505868
-
Antiretroviral prophylaxis for HIV prevention in heterosexual men and women
-
Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367(5):399-410.
-
(2012)
N Engl J Med
, vol.367
, Issue.5
, pp. 399-410
-
-
Baeten, J.M.1
Donnell, D.2
Ndase, P.3
Mugo, N.R.4
Campbell, J.D.5
Wangisi, J.6
-
10
-
-
84881175660
-
Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis
-
Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, et al. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis. Infect Control Hosp Epidemiol. 2013;34(9):875-92.
-
(2013)
Infect Control Hosp Epidemiol
, vol.34
, Issue.9
, pp. 875-892
-
-
Kuhar, D.T.1
Henderson, D.K.2
Struble, K.A.3
Heneine, W.4
Thomas, V.5
Cheever, L.W.6
-
11
-
-
0036239507
-
Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission
-
Cooper ER, Charurat M, Mofenson L, Hanson IC, Pitt J, Diaz C, et al. Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. J Acquir Immune Defic Syndr. 2002;29(5):484-94. (Pubitemid 34456340)
-
(2002)
Journal of Acquired Immune Deficiency Syndromes
, vol.29
, Issue.5
, pp. 484-494
-
-
Cooper, E.R.1
Charurat, M.2
Mofenson, L.3
Hanson, I.C.4
Pitt, J.5
Diaz, C.6
Hayani, K.7
Handelsman, E.8
Smeriglio, V.9
Hoff, R.10
Blattner, W.11
-
12
-
-
77953725982
-
Antiretroviral regimens in pregnancy and breast-feeding in Botswana
-
Shapiro RL, Hughes MD, Ogwu A, Kitch D, Lockman S, Moffat C, et al. Antiretroviral regimens in pregnancy and breast-feeding in Botswana. N Engl J Med. 2010;362(24):2282-94.
-
(2010)
N Engl J Med
, vol.362
, Issue.24
, pp. 2282-2294
-
-
Shapiro, R.L.1
Hughes, M.D.2
Ogwu, A.3
Kitch, D.4
Lockman, S.5
Moffat, C.6
-
13
-
-
0032839482
-
Antiretroviral-drug concentrations in semen: Implications for sexual transmission of human immunodeficiency virus type 1
-
Kashuba AD, Dyer JR, Kramer LM, Raasch RH, Eron JJ, Cohen MS. Antiretroviral-drug concentrations in semen: implications for sexual transmission of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1999;43(8):1817-26. (Pubitemid 29395171)
-
(1999)
Antimicrobial Agents and Chemotherapy
, vol.43
, Issue.8
, pp. 1817-1826
-
-
Kashuba, A.D.M.1
Dyer, J.R.2
Kramer, L.M.3
Raasch, R.H.4
Eron, J.J.5
Cohen, M.S.6
-
15
-
-
83455179327
-
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: The male and female genital tract
-
Else LJ, Taylor S, Back DJ, Khoo SH. Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract. Antivir Ther. 2011;16(8):1149-67.
-
(2011)
Antivir Ther
, vol.16
, Issue.8
, pp. 1149-1167
-
-
Else, L.J.1
Taylor, S.2
Back, D.J.3
Khoo, S.H.4
-
16
-
-
0031891641
-
Physiological changes during the menstrual cycle and their effects on the pharmacokinetics and pharmacodynamics of drugs
-
DOI 10.2165/00003088-199834030-00003
-
Kashuba AD, Nafziger AN. Physiological changes during the menstrual cycle and their effects on the pharmacokinetics and pharmacodynamics of drugs. Clin Pharmacokinet. 1998;34(3):203-18. (Pubitemid 28112399)
-
(1998)
Clinical Pharmacokinetics
, vol.34
, Issue.3
, pp. 203-218
-
-
Kashuba, A.D.M.1
Nafziger, A.N.2
-
17
-
-
79959938249
-
High susceptibility to repeated, low-dose, vaginal SHIV exposure late in the luteal phase of the menstrual cycle of pigtail macaques
-
Vishwanathan SA, Guenthner PC, Lin CY, Dobard C, Sharma S, Adams DR, et al. High susceptibility to repeated, low-dose, vaginal SHIV exposure late in the luteal phase of the menstrual cycle of pigtail macaques. J Acquir Immune Defic Syndr. 2011;57(4):261-4.
-
(2011)
J Acquir Immune Defic Syndr
, vol.57
, Issue.4
, pp. 261-264
-
-
Vishwanathan, S.A.1
Guenthner, P.C.2
Lin, C.Y.3
Dobard, C.4
Sharma, S.5
Adams, D.R.6
-
18
-
-
68449086889
-
Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women
-
Dumond JB, Patterson KB, Pecha AL, Werner RE, Andrews E, Damle B, et al. Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women. J Acquir Immune Defic Syndr. 2009;51(5):546-53.
-
(2009)
J Acquir Immune Defic Syndr
, vol.51
, Issue.5
, pp. 546-553
-
-
Dumond, J.B.1
Patterson, K.B.2
Pecha, A.L.3
Werner, R.E.4
Andrews, E.5
Damle, B.6
-
19
-
-
83155177076
-
Penetration of tenofovir and emtricitabine in mucosal tissues: Implications for prevention of HIV-1 transmission
-
Patterson KB, Prince HA, Kraft E, Jenkins AJ, Shaheen NJ, Rooney JF, et al. Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission. Sci Transl Med. 2011;3(112):112re4.
-
(2011)
Sci Transl Med
, vol.3
, Issue.112
-
-
Patterson, K.B.1
Prince, H.A.2
Kraft, E.3
Jenkins, A.J.4
Shaheen, N.J.5
Rooney, J.F.6
-
20
-
-
84893485078
-
Single and multiple dose pharmacokinetics of dolutegravir in the genital tract of HIV-negative women
-
Adams JL, Patterson KB, Prince HM, Sykes C, Greener BN, Dumond JB, et al. Single and multiple dose pharmacokinetics of dolutegravir in the genital tract of HIV-negative women. Antivir Ther. 2014;18(8):1005-13.
-
(2014)
Antivir Ther
, vol.18
, Issue.8
, pp. 1005-1013
-
-
Adams, J.L.1
Patterson, K.B.2
Prince, H.M.3
Sykes, C.4
Greener, B.N.5
Dumond, J.B.6
-
21
-
-
84903722051
-
Characterizing antiretroviral distribution within active viral reservoirs using mass spectrometry imaging
-
Thompson CG, Rosen E, Sykes C, Fedoriw Y, Luciw P, Muddiman DC, et al. Characterizing antiretroviral distribution within active viral reservoirs using mass spectrometry imaging. 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy; 19-21 May 2014; Washington, DC.
-
15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy; 19-21 May 2014; Washington, DC
-
-
Thompson, C.G.1
Rosen, E.2
Sykes, C.3
Fedoriw, Y.4
Luciw, P.5
Muddiman, D.C.6
-
22
-
-
73549088038
-
Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine
-
Cihlar T, Ray AS. Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine. Antiviral Res. 2010;85(1):39-58.
-
(2010)
Antiviral Res
, vol.85
, Issue.1
, pp. 39-58
-
-
Cihlar, T.1
Ray, A.S.2
-
23
-
-
34548267289
-
Antiretroviral drug exposure in the female genital tract: Implications for oral pre- and post-exposure prophylaxis
-
DOI 10.1097/QAD.0b013e328270385a, PII 0000203020070912000009
-
Dumond JB, Yeh RF, Patterson KB, Corbett AH, Jung BH, Rezk NL, et al. Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis. AIDS. 2007;21(14):1899-907. (Pubitemid 47329766)
-
(2007)
AIDS
, vol.21
, Issue.14
, pp. 1899-1907
-
-
Dumond, J.B.1
Yeh, R.F.2
Patterson, K.B.3
Corbett, A.H.4
Jung, B.H.5
Rezk, N.L.6
Bridges, A.S.7
Stewart, P.W.8
Cohen, M.S.9
Kashuba, A.D.M.10
-
24
-
-
39749124255
-
Antiretroviral drug concentrations and HIV RNA in the genital tract of HIV-infected women receiving long-term highly active antiretroviral therapy
-
DOI 10.1086/527387
-
Kwara A, Delong A, Rezk N, Hogan J, Burtwell H, Chapman S, et al. Antiretroviral drug concentrations and HIV RNA in the genital tract of HIV-infected women receiving long-term highly active antiretroviral therapy. Clin Infect Dis. 2008;46(5):719-25. (Pubitemid 351321556)
-
(2008)
Clinical Infectious Diseases
, vol.46
, Issue.5
, pp. 719-725
-
-
Kwara, A.1
DeLong, A.2
Rezk, N.3
Hogan, J.4
Burtwell, H.5
Chapman, S.6
Moreira, C.C.7
Kurpewski, J.8
Ingersoll, J.9
Caliendo, A.M.10
Kashuba, A.11
Cu-Uvin, S.12
-
25
-
-
77958468743
-
Pharmacologic opportunities for HIV prevention
-
Nicol MR, Kashuba AD. Pharmacologic opportunities for HIV prevention. Clin Pharmacol Ther. 2010;88(5):598-609.
-
(2010)
Clin Pharmacol Ther
, vol.88
, Issue.5
, pp. 598-609
-
-
Nicol, M.R.1
Kashuba, A.D.2
-
26
-
-
84886705161
-
Single dose pharmacokinetics of oral tenofovir in plasma, peripheral blood mononuclear cells, colonic tissue, and vaginal tissue
-
Louissaint NA, Cao YJ, Skipper PL, Liberman RG, Tannenbaum SR, Nimmagadda S, et al. Single dose pharmacokinetics of oral tenofovir in plasma, peripheral blood mononuclear cells, colonic tissue, and vaginal tissue. AIDS Res Hum Retrovir. 2013;29(11):1443-50.
-
(2013)
AIDS Res Hum Retrovir
, vol.29
, Issue.11
, pp. 1443-1450
-
-
Louissaint, N.A.1
Cao, Y.J.2
Skipper, P.L.3
Liberman, R.G.4
Tannenbaum, S.R.5
Nimmagadda, S.6
-
27
-
-
72749106653
-
The complexities of antiretroviral drug-drug interactions: Role of ABC and SLC transporters
-
Kis O, Robillard K, Chan GN, Bendayan R. The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters. Trends Pharmacol Sci. 2010;31(1):22-35.
-
(2010)
Trends Pharmacol Sci
, vol.31
, Issue.1
, pp. 22-35
-
-
Kis, O.1
Robillard, K.2
Chan, G.N.3
Bendayan, R.4
-
28
-
-
84885450494
-
Global expression of molecular transporters in the human vaginal tract: Implications for HIV chemoprophylaxis
-
Gunawardana M, Mullen M, Moss JA, Pyles RB, Nusbaum RJ, Patel J, et al. Global expression of molecular transporters in the human vaginal tract: implications for HIV chemoprophylaxis. PLoS One. 2013;8(10):e77340.
-
(2013)
PLoS One
, vol.8
, Issue.10
-
-
Gunawardana, M.1
Mullen, M.2
Moss, J.A.3
Pyles, R.B.4
Nusbaum, R.J.5
Patel, J.6
-
29
-
-
84886712328
-
Short communication: Expression of transporters and metabolizing enzymes in the female lower genital tract: Implications for microbicide research
-
Zhou T, Hu M, Cost M, Poloyac S, Rohan L. Short communication: expression of transporters and metabolizing enzymes in the female lower genital tract: implications for microbicide research. AIDS Res Hum Retrovir. 2013;29(11):1496-503.
-
(2013)
AIDS Res Hum Retrovir
, vol.29
, Issue.11
, pp. 1496-1503
-
-
Zhou, T.1
Hu, M.2
Cost, M.3
Poloyac, S.4
Rohan, L.5
-
30
-
-
80054786208
-
A multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gel
-
Schwartz JL, Rountree W, Kashuba AD, Brache V, Creinin MD, Poindexter A, et al. A multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gel. PLoS One. 2011;6(10):e25974.
-
(2011)
PLoS One
, vol.6
, Issue.10
-
-
Schwartz, J.L.1
Rountree, W.2
Kashuba, A.D.3
Brache, V.4
Creinin, M.D.5
Poindexter, A.6
-
31
-
-
84873858944
-
MTN-001: Randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments
-
Hendrix CW, Chen BA, Guddera V, Hoesley C, Justman J, Nakabiito C, et al. MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments. PLoS One. 2013;8(1):e55013.
-
(2013)
PLoS One
, vol.8
, Issue.1
-
-
Hendrix, C.W.1
Chen, B.A.2
Guddera, V.3
Hoesley, C.4
Justman, J.5
Nakabiito, C.6
-
32
-
-
0032580479
-
HIV-protease inhibitors
-
DOI 10.1056/NEJM199804303381808
-
Flexner C. HIV-protease inhibitors. N Engl J Med. 1998;338(18):1281-92. (Pubitemid 28216584)
-
(1998)
New England Journal of Medicine
, vol.338
, Issue.18
, pp. 1281-1292
-
-
Flexner, C.1
-
33
-
-
79952358744
-
Darunavir, ritonavir, and etravirine pharmacokinetics in the cervicovaginal fluid and blood plasma of HIV-infected women
-
Patterson K, Jennings S, Falcon R, Mrus J, Kashuba A. Darunavir, ritonavir, and etravirine pharmacokinetics in the cervicovaginal fluid and blood plasma of HIV-infected women. Antimicrob Agents Chemother. 2011;55(3):1120-2.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.3
, pp. 1120-1122
-
-
Patterson, K.1
Jennings, S.2
Falcon, R.3
Mrus, J.4
Kashuba, A.5
-
34
-
-
9144268273
-
Differential Diffusions of Indinavir and Lopinavir in Genital Secretions of Human Immunodeficiency Virus-Infected Women
-
DOI 10.1128/AAC.48.2.632-634.2004
-
Launay O, Tod M, Louchahi K, Belarbi L, Bouchaud O, Memain N, et al. Differential diffusions of indinavir and lopinavir in genital secretions of human immunodeficiency virus-infected women. Antimicrob Agents Chemother. 2004;48(2):632-4. (Pubitemid 38141731)
-
(2004)
Antimicrobial Agents and Chemotherapy
, vol.48
, Issue.2
, pp. 632-634
-
-
Launay, O.1
Tod, M.2
Louchahi, K.3
Belarbi, L.4
Bouchaud, O.5
Memain, N.6
Petitjean, O.7
Robineau, M.8
Guillevin, L.9
Lortholary, O.10
-
35
-
-
0141481966
-
Protein binding in antiretroviral therapies
-
DOI 10.1089/088922203769232629
-
Boffito M, Back DJ, Blaschke TF, Rowland M, Bertz RJ, Gerber JG, et al. Protein binding in antiretroviral therapies. AIDS Res Hum Retrovir. 2003;19(9):825-35. (Pubitemid 37215138)
-
(2003)
AIDS Research and Human Retroviruses
, vol.19
, Issue.9
, pp. 825-835
-
-
Boffito, M.1
Back, D.J.2
Blaschke, T.F.3
Rowland, M.4
Bertz, R.J.5
Gerber, J.G.6
Miller, V.7
-
36
-
-
0026029328
-
Quantitation of albumin and alpha-1-acid glycoprotein in human cervical mucus
-
Salas Herrera IG, Pearson RM, Turner P. Quantitation of albumin and alpha-1-acid glycoprotein in human cervical mucus. Hum Exp Toxicol. 1991;10(2):137-9.
-
(1991)
Hum Exp Toxicol
, vol.10
, Issue.2
, pp. 137-139
-
-
Salas Herrera, I.G.1
Pearson, R.M.2
Turner, P.3
-
37
-
-
84886707973
-
Increasing extracellular protein concentration reduces intracellular antiretroviral drug concentration and antiviral effect
-
Avery LB, Zarr MA, Bakshi RP, Siliciano RF, Hendrix CW. Increasing extracellular protein concentration reduces intracellular antiretroviral drug concentration and antiviral effect. AIDS Res Hum Retrovir. 2013;29(11):1434-42.
-
(2013)
AIDS Res Hum Retrovir
, vol.29
, Issue.11
, pp. 1434-1442
-
-
Avery, L.B.1
Zarr, M.A.2
Bakshi, R.P.3
Siliciano, R.F.4
Hendrix, C.W.5
-
38
-
-
84898657998
-
Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention
-
Nicol MR, Fedoriw Y, Mathews M, Prince HM, Patterson KB, Geller E, et al. Expression of six drug transporters in vaginal, cervical, and colorectal tissues: implications for drug disposition in HIV prevention. J Clin Pharmacol. 2014;54(5):574-83.
-
(2014)
J Clin Pharmacol
, vol.54
, Issue.5
, pp. 574-583
-
-
Nicol, M.R.1
Fedoriw, Y.2
Mathews, M.3
Prince, H.M.4
Patterson, K.B.5
Geller, E.6
-
39
-
-
84862575892
-
Etravirine concentrations in the cervicovaginal compartment in HIV-1-infected women receiving etravirine-containing antiretroviral therapy: DIVA 02 study
-
Clavel C, Peytavin G, Tubiana R, Soulie C, Courbon E, Crenn-Hebert C, et al. Etravirine concentrations in the cervicovaginal compartment in HIV-1-infected women receiving etravirine-containing antiretroviral therapy: DIVA 02 study. Antimicrob Agents Chemother. 2012;56(7):4018-20.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.7
, pp. 4018-4020
-
-
Clavel, C.1
Peytavin, G.2
Tubiana, R.3
Soulie, C.4
Courbon, E.5
Crenn-Hebert, C.6
-
40
-
-
10644295700
-
Protease inhibitor and nonnucleoside reverse transcriptase inhibitor concentrations in the genital tract of HIV-1-infected women
-
DOI 10.1097/00126334-200412150-00008
-
Min SS, Corbett AH, Rezk N, Cu-Uvin S, Fiscus SA, Petch L, et al. Protease inhibitor and nonnucleoside reverse transcriptase inhibitor concentrations in the genital tract of HIV-1-infected women. J Acquir Immune Defic Syndr. 2004;37(5):1577-80. (Pubitemid 39658196)
-
(2004)
Journal of Acquired Immune Deficiency Syndromes
, vol.37
, Issue.5
, pp. 1577-1580
-
-
Min, S.S.1
Corbett, A.H.2
Rezk, N.3
Cu-Uvin, S.4
Fiscus, S.A.5
Petch, L.6
Cohen, M.S.7
Kashuba, A.D.M.8
-
41
-
-
66549104708
-
-
Princeton: Bristol-Myers Squibb
-
Sustiva® [package insert]. Princeton: Bristol-Myers Squibb; 2008.
-
(2008)
Sustiva® [Package Insert]
-
-
-
42
-
-
65549153833
-
-
Raritan: Tibotec Therapeutics
-
Intelence® [package insert]. Raritan: Tibotec Therapeutics; 2008.
-
(2008)
Intelence® [Package Insert]
-
-
-
43
-
-
0013605495
-
-
Ridgefield: Boehringer Ingelheim Pharmaceuticals, Inc.
-
Viramune® [package insert]. Ridgefield: Boehringer Ingelheim Pharmaceuticals, Inc.; 1996.
-
(1996)
Viramune® [Package Insert]
-
-
-
44
-
-
78649266105
-
Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women
-
Nel AM, Coplan P, Smythe SC, McCord K, Mitchnick M, Kaptur PE, et al. Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS Res Hum Retrovir. 2010;26(11):1181-90.
-
(2010)
AIDS Res Hum Retrovir
, vol.26
, Issue.11
, pp. 1181-1190
-
-
Nel, A.M.1
Coplan, P.2
Smythe, S.C.3
McCord, K.4
Mitchnick, M.5
Kaptur, P.E.6
-
46
-
-
84929911975
-
Safety and pharmacokinetics/pharmacodynamics of dapivirine and maraviroc vaginal rings
-
abstract no. 41
-
Chen BA, Panther L, Hoesley C, Hendrix C, van der Straten A, Husnik M, et al. Safety and pharmacokinetics/pharmacodynamics of dapivirine and maraviroc vaginal rings [abstract no. 41]. 21st Conference on Retroviruses and Opportunistic Infections; 3-6 Mar 2014; Boston.
-
21st Conference on Retroviruses and Opportunistic Infections; 3-6 Mar 2014; Boston
-
-
Chen, B.A.1
Panther, L.2
Hoesley, C.3
Hendrix, C.4
Van Der Straten, A.5
Husnik, M.6
-
47
-
-
27644510382
-
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
-
DOI 10.1128/AAC.49.11.4721-4732.2005
-
Dorr P, Westby M, Dobbs S, Griffin P, Irvine B, Macartney M, et al. Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity. Antimicrob Agents Chemother. 2005;49(11):4721-32. (Pubitemid 41552605)
-
(2005)
Antimicrobial Agents and Chemotherapy
, vol.49
, Issue.11
, pp. 4721-4732
-
-
Dorr, P.1
Westby, M.2
Dobbs, S.3
Griffin, P.4
Irvine, B.5
Macartney, M.6
Mori, J.7
Rickett, G.8
Smith-Burchnell, C.9
Napier, C.10
Webster, R.11
Armour, D.12
Price, D.13
Stammen, B.14
Wood, A.15
Perros, M.16
-
48
-
-
0031575431
-
Change in coreceptor use correlates with disease progression in HIV-1- infected individuals
-
DOI 10.1084/jem.185.4.621
-
Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med. 1997;185(4):621-8. (Pubitemid 27098147)
-
(1997)
Journal of Experimental Medicine
, vol.185
, Issue.4
, pp. 621-628
-
-
Connor, R.I.1
Sheridan, K.E.2
Ceradini, D.3
Choe, S.4
Landau, N.R.5
-
49
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
DOI 10.1146/annurev.immunol.17.1.657
-
Berger EA, Murphy PM, Farber JM. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu Rev Immunol. 1999;17:657-700. (Pubitemid 29241137)
-
(1999)
Annual Review of Immunology
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
50
-
-
9944249580
-
Chemokine receptor expression in the human ectocervix: Implications for infection by the human immunodeficiency virus-type I
-
DOI 10.1111/j.1365-2567.2004.01990.x
-
Yeaman GR, Asin S, Weldon S, Demian DJ, Collins JE, Gonzalez JL, et al. Chemokine receptor expression in the human ectocervix: implications for infection by the human immunodeficiency virus-type I. Immunology. 2004;113(4):524-33. (Pubitemid 39593371)
-
(2004)
Immunology
, vol.113
, Issue.4
, pp. 524-533
-
-
Yeaman, G.R.1
Asin, S.2
Weldon, S.3
Demian, D.J.4
Collins, J.E.5
Gonzalez, J.L.6
Wira, C.R.7
Fanger, M.W.8
Howell, A.L.9
-
51
-
-
84873580295
-
Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques
-
Malcolm RK, Forbes CJ, Geer L, Veazey RS, Goldman L, Klasse PJ, et al. Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques. J Antimicrob Chemother. 2013;68(3):678-83.
-
(2013)
J Antimicrob Chemother
, vol.68
, Issue.3
, pp. 678-683
-
-
Malcolm, R.K.1
Forbes, C.J.2
Geer, L.3
Veazey, R.S.4
Goldman, L.5
Klasse, P.J.6
-
52
-
-
84860210623
-
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques
-
Malcolm RK, Veazey RS, Geer L, Lowry D, Fetherston SM, Murphy DJ, et al. Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques. Antimicrob Agents Chemother. 2012;56(5):2251-8.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.5
, pp. 2251-2258
-
-
Malcolm, R.K.1
Veazey, R.S.2
Geer, L.3
Lowry, D.4
Fetherston, S.M.5
Murphy, D.J.6
-
53
-
-
44049098954
-
-
Whitehouse Station: Merck & Co., Inc.;
-
Isentress® [package insert]. Whitehouse Station: Merck & Co., Inc.; 2007.
-
(2007)
Isentress® [Package Insert]
-
-
-
54
-
-
47949120697
-
Raltegravir with optimized background therapy for resistant HIV-1 infection
-
Steigbigel RT, Cooper DA, Kumar PN, Eron JE, Schechter M, Markowitz M, et al. Raltegravir with optimized background therapy for resistant HIV-1 infection. N Engl J Med. 2008;359(4):339-54.
-
(2008)
N Engl J Med
, vol.359
, Issue.4
, pp. 339-354
-
-
Steigbigel, R.T.1
Cooper, D.A.2
Kumar, P.N.3
Eron, J.E.4
Schechter, M.5
Markowitz, M.6
-
55
-
-
84896898426
-
-
Research Triangle Park: GlaxoSmithKline
-
Tivicay® [package insert]. Research Triangle Park: GlaxoSmithKline; 2013.
-
(2013)
Tivicay® [Package Insert]
-
-
-
57
-
-
79956314183
-
Raltegravir concentrations in the genital tract of HIV-1-infected women treated with a raltegravir-containing regimen (DIVA 01 study)
-
Clavel C, Peytavin G, Tubiana R, Soulie C, Crenn-Hebert C, Heard I, et al. Raltegravir concentrations in the genital tract of HIV-1-infected women treated with a raltegravir-containing regimen (DIVA 01 study). Antimicrob Agents Chemother. 2011;55(6):3018-21.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.6
, pp. 3018-3021
-
-
Clavel, C.1
Peytavin, G.2
Tubiana, R.3
Soulie, C.4
Crenn-Hebert, C.5
Heard, I.6
-
58
-
-
84872696364
-
In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor
-
Reese MJ, Savina PM, Generaux GT, Tracey H, Humphreys JE, Kanaoka E, et al. In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor. Drug Metab Dispos. 2013;41(2):353-61.
-
(2013)
Drug Metab Dispos
, vol.41
, Issue.2
, pp. 353-361
-
-
Reese, M.J.1
Savina, P.M.2
Generaux, G.T.3
Tracey, H.4
Humphreys, J.E.5
Kanaoka, E.6
-
59
-
-
84886711813
-
Pharmacokinetics and pharmacodynamics in HIV prevention; current status and future directions: A summary of the DAIDS and BMGF sponsored think tank on pharmacokinetics (PK)/pharmacodynamics (PD) in HIV prevention
-
Romano J, Kashuba A, Becker S, Cummins J, Turpin J, Veronese F. Pharmacokinetics and pharmacodynamics in HIV prevention; current status and future directions: a summary of the DAIDS and BMGF sponsored think tank on pharmacokinetics (PK)/pharmacodynamics (PD) in HIV prevention. AIDS Res Hum Retrovir. 2013;29(11):1418-27.
-
(2013)
AIDS Res Hum Retrovir
, vol.29
, Issue.11
, pp. 1418-1427
-
-
Romano, J.1
Kashuba, A.2
Becker, S.3
Cummins, J.4
Turpin, J.5
Veronese, F.6
-
61
-
-
79960372412
-
Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: Implications for HIV prevention in women
-
Karim SS, Kashuba AD, Werner L, Karim QA. Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women. Lancet. 2011;378(9787):279-81.
-
(2011)
Lancet
, vol.378
, Issue.9787
, pp. 279-281
-
-
Karim, S.S.1
Kashuba, A.D.2
Werner, L.3
Karim, Q.A.4
-
62
-
-
77949409948
-
Targeting early infection to prevent HIV-1 mucosal transmission
-
Haase AT. Targeting early infection to prevent HIV-1 mucosal transmission. Nature. 2010;464(7286):217-23.
-
(2010)
Nature
, vol.464
, Issue.7286
, pp. 217-223
-
-
Haase, A.T.1
-
63
-
-
84883450718
-
Pre-exposure prophylaxis for HIV in women: Daily oral tenofovir, oral tenofovir/emtricitabine or vaginal tenofovir gel in the VOICE study (MTN 003)
-
Marrazzo J, Ramjee G, Nair G, Palanee T, Mkhize B, Nakabiito Taljaard M, et al. Pre-exposure prophylaxis for HIV in women: daily oral tenofovir, oral tenofovir/emtricitabine or vaginal tenofovir gel in the VOICE study (MTN 003). 20th Conference on Retroviruses and Opportunistic Infections; 3-6 Mar 2013; Atlanta.
-
20th Conference on Retroviruses and Opportunistic Infections; 3-6 Mar 2013; Atlanta
-
-
Marrazzo, J.1
Ramjee, G.2
Nair, G.3
Palanee, T.4
Mkhize, B.5
Nakabiito Taljaard, M.6
-
64
-
-
84884634016
-
Adherence to antiretroviral prophylaxis for HIV prevention: A substudy cohort within a clinical trial of serodiscordant couples in East Africa
-
Haberer JE, Baeten JM, Campbell J, Wangisi J, Katabira E, Ronald A, et al. Adherence to antiretroviral prophylaxis for HIV prevention: a substudy cohort within a clinical trial of serodiscordant couples in East Africa. PLoS Med. 2013;10(9):e1001511.
-
(2013)
PLoS Med
, vol.10
, Issue.9
-
-
Haberer, J.E.1
Baeten, J.M.2
Campbell, J.3
Wangisi, J.4
Katabira, E.5
Ronald, A.6
-
65
-
-
84885068247
-
Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges
-
Smith JM, Rastogi R, Teller RS, Srinivasan P, Mesquita PM, Nagaraja U, et al. Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges. Proc Natl Acad Sci USA. 2013;110(40):16145-50.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.40
, pp. 16145-16150
-
-
Smith, J.M.1
Rastogi, R.2
Teller, R.S.3
Srinivasan, P.4
Mesquita, P.M.5
Nagaraja, U.6
-
66
-
-
84886089649
-
Long-acting injectable antiretrovirals for HIV treatment and prevention
-
Spreen WR, Margolis DA, Pottage JC Jr. Long-acting injectable antiretrovirals for HIV treatment and prevention. Curr Opin HIV AIDS. 2013;8(6):565-71.
-
(2013)
Curr Opin HIV AIDS
, vol.8
, Issue.6
, pp. 565-571
-
-
Spreen, W.R.1
Margolis, D.A.2
Pottage Jr., J.C.3
-
67
-
-
84889888338
-
Development of dapivirine vaginal ring for HIV prevention
-
Devlin B, Nuttall J, Wilder S, Woodsong C, Rosenberg Z. Development of dapivirine vaginal ring for HIV prevention. Antiviral Res. 2013;100(Suppl):S3-8.
-
(2013)
Antiviral Res
, vol.100
, Issue.SUPPL.
-
-
Devlin, B.1
Nuttall, J.2
Wilder, S.3
Woodsong, C.4
Rosenberg, Z.5
-
68
-
-
77953942340
-
HIV transmission risk through anal intercourse: Systematic review, meta-analysis and implications for HIV prevention
-
Baggaley RF, White RG, Boily MC. HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV prevention. Int J Epidemiol. 2010;39(4):1048-63.
-
(2010)
Int J Epidemiol
, vol.39
, Issue.4
, pp. 1048-1063
-
-
Baggaley, R.F.1
White, R.G.2
Boily, M.C.3
-
69
-
-
77954051000
-
High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men
-
Li H, Bar KJ, Wang S, Decker JM, Chen Y, Sun C, et al. High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men. PLoS Pathog. 2010;6(5):e1000890.
-
(2010)
PLoS Pathog
, vol.6
, Issue.5
-
-
Li, H.1
Bar, K.J.2
Wang, S.3
Decker, J.M.4
Chen, Y.5
Sun, C.6
-
70
-
-
84886802405
-
Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: Where do we go from here?
-
Cohen MS, Smith MK, Muessig KE, Hallett TB, Powers KA, Kashuba AD. Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here? Lancet. 2013;382(9903):1515-24.
-
(2013)
Lancet
, vol.382
, Issue.9903
, pp. 1515-1524
-
-
Cohen, M.S.1
Smith, M.K.2
Muessig, K.E.3
Hallett, T.B.4
Powers, K.A.5
Kashuba, A.D.6
-
71
-
-
33846420624
-
Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir
-
DOI 10.1124/mol.106.028233
-
Imaoka T, Kusuhara H, Adachi M, Schuetz JD, Takeuchi K, Sugiyama Y. Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir. Mol Pharmacol. 2007;71(2):619-27. (Pubitemid 46147926)
-
(2007)
Molecular Pharmacology
, vol.71
, Issue.2
, pp. 619-627
-
-
Imaoka, T.1
Kusuhara, H.2
Adachi, M.3
Schuetz, J.D.4
Takeuchi, K.5
Sugiyama, Y.6
-
72
-
-
33749531758
-
Mechanism of active renal tubular efflux of tenofovir
-
DOI 10.1128/AAC.00251-06
-
Ray AS, Cihlar T, Robinson KL, Tong L, Vela JE, Fuller MD, et al. Mechanism of active renal tubular efflux of tenofovir. Antimicrob Agents Chemother. 2006;50(10):3297-304. (Pubitemid 44527501)
-
(2006)
Antimicrobial Agents and Chemotherapy
, vol.50
, Issue.10
, pp. 3297-3304
-
-
Ray, A.S.1
Cihlar, T.2
Robinson, K.L.3
Tong, L.4
Vela, J.E.5
Fuller, M.D.6
Wieman, L.M.7
Eisenberg, E.J.8
Rhodes, G.R.9
-
73
-
-
42049090195
-
Clinical and genetic determinants of intracellular tenofovir diphosphate concentrations in HIV-infected patients
-
DOI 10.1097/QAI.0b013e31815e7478, PII 0012633420080301000005
-
Kiser JJ, Aquilante CL, Anderson PL, King TM, Carten ML, Fletcher CV. Clinical and genetic determinants of intracellular tenofovir diphosphate concentrations in HIV-infected patients. J Acquir Immune Defic Syndr. 2008;47(3):298-303. (Pubitemid 351619414)
-
(2008)
Journal of Acquired Immune Deficiency Syndromes
, vol.47
, Issue.3
, pp. 298-303
-
-
Kiser, J.J.1
Aquilante, C.L.2
Anderson, P.L.3
King, T.M.4
Carten, M.L.5
Fletcher, C.V.6
-
74
-
-
22944433202
-
Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6)
-
DOI 10.1124/jpet.105.084301
-
Bleasby K, Hall LA, Perry JL, Mohrenweiser HW, Pritchard JB. Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6). J Pharmacol Exp Ther. 2005;314(2):923-31. (Pubitemid 41043879)
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.314
, Issue.2
, pp. 923-931
-
-
Bleasby, K.1
Hall, L.A.2
Perry, J.L.3
Mohrenweiser, H.W.4
Pritchard, J.B.5
-
75
-
-
30344432397
-
Multidrug resistance-associated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites
-
DOI 10.1080/00498250500354493, PII K666U3180564Q404
-
Mallants R, Van Oosterwyck K, Van Vaeck L, Mols R, De Clercq E, Augustijns P. Multidrug resistance-associated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites. Xenobiotica. 2005;10-11(35):1055-66. (Pubitemid 43068047)
-
(2005)
Xenobiotica
, vol.35
, Issue.10-11
, pp. 1055-1066
-
-
Mallants, R.1
Van Oosterwyck, K.2
Van Vaeck, L.3
Mols, R.4
De Clercq, E.5
Augustijns, P.6
-
76
-
-
84868474359
-
RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate
-
Anton PA, Cranston RD, Kashuba A, Hendrix CW, Bumpus NN, Richardson-Harman N, et al. RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate. AIDS Res Hum Retrovir. 2012;28(11):1412-21.
-
(2012)
AIDS Res Hum Retrovir
, vol.28
, Issue.11
, pp. 1412-1421
-
-
Anton, P.A.1
Cranston, R.D.2
Kashuba, A.3
Hendrix, C.W.4
Bumpus, N.N.5
Richardson-Harman, N.6
-
77
-
-
84867005260
-
Single- and multiple-dose pharmacokinetics of darunavir plus ritonavir and etravirine in semen and rectal tissue of HIV-negative men
-
Brown KC, Patterson KB, Jennings SH, Malone SA, Shaheen NJ, Asherrince HM, et al. Single- and multiple-dose pharmacokinetics of darunavir plus ritonavir and etravirine in semen and rectal tissue of HIV-negative men. J Acquir Immune Defic Syndr. 2012;61(2):138-44.
-
(2012)
J Acquir Immune Defic Syndr
, vol.61
, Issue.2
, pp. 138-144
-
-
Brown, K.C.1
Patterson, K.B.2
Jennings, S.H.3
Malone, S.A.4
Shaheen, N.J.5
Asherrince, H.M.6
-
79
-
-
84879084001
-
Differential penetration of raltegravir throughout gastrointestinal tissue: Implications for eradication and cure
-
Patterson KB, Prince HA, Stevens T, Shaheen NJ, Dellon ES, Madanick RD, et al. Differential penetration of raltegravir throughout gastrointestinal tissue: implications for eradication and cure. AIDS. 2013;27(9):1413-9.
-
(2013)
AIDS
, vol.27
, Issue.9
, pp. 1413-1419
-
-
Patterson, K.B.1
Prince, H.A.2
Stevens, T.3
Shaheen, N.J.4
Dellon, E.S.5
Madanick, R.D.6
-
80
-
-
84883385762
-
Dolutegravir pharmacokinetics in the genital tract and colorectum of HIV-negative men after single and multiple dosing
-
Greener BN, Patterson KB, Prince HM, Sykes CS, Adams JL, Dumond JB, et al. Dolutegravir pharmacokinetics in the genital tract and colorectum of HIV-negative men after single and multiple dosing. J Acquir Immune Defic Syndr. 2013;64(1):39-44.
-
(2013)
J Acquir Immune Defic Syndr
, vol.64
, Issue.1
, pp. 39-44
-
-
Greener, B.N.1
Patterson, K.B.2
Prince, H.M.3
Sykes, C.S.4
Adams, J.L.5
Dumond, J.B.6
-
81
-
-
73849124557
-
Pharmacokinetics and safety of S/GSK1349572, a next-generation HIV integrase inhibitor, in healthy volunteers
-
Min S, Song I, Borland J, Chen S, Lou Y, Fujiwara T, et al. Pharmacokinetics and safety of S/GSK1349572, a next-generation HIV integrase inhibitor, in healthy volunteers. Antimicrob Agents Chemother. 2010;54(1):254-8.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.1
, pp. 254-258
-
-
Min, S.1
Song, I.2
Borland, J.3
Chen, S.4
Lou, Y.5
Fujiwara, T.6
-
82
-
-
79954988179
-
Single and multiple dose pharmacokinetics of maraviroc in saliva, semen, and rectal tissue of healthy HIV-negative men
-
Brown KC, Patterson KB, Malone SA, Shaheen NJ, Prince HM, Dumond JB, et al. Single and multiple dose pharmacokinetics of maraviroc in saliva, semen, and rectal tissue of healthy HIV-negative men. J Infect Dis. 2011;203(10):1484-90.
-
(2011)
J Infect Dis
, vol.203
, Issue.10
, pp. 1484-1490
-
-
Brown, K.C.1
Patterson, K.B.2
Malone, S.A.3
Shaheen, N.J.4
Prince, H.M.5
Dumond, J.B.6
-
83
-
-
48549083877
-
-
Research Triangle Park: ViiV Healthcare
-
Selzentry® [package insert]. Research Triangle Park: ViiV Healthcare; 2007.
-
(2007)
Selzentry® [Package Insert]
-
-
-
84
-
-
80051753726
-
HIV-1 RNA rectal shedding is reduced in men with low plasma HIV-1 RNA viral loads and is not enhanced by sexually transmitted bacterial infections of the rectum
-
Kelley CF, Haaland RE, Patel P, Evans-Strickfaden T, Farshy C, Hanson D, et al. HIV-1 RNA rectal shedding is reduced in men with low plasma HIV-1 RNA viral loads and is not enhanced by sexually transmitted bacterial infections of the rectum. J Infect Dis. 2011;204(5):761-7.
-
(2011)
J Infect Dis
, vol.204
, Issue.5
, pp. 761-767
-
-
Kelley, C.F.1
Haaland, R.E.2
Patel, P.3
Evans-Strickfaden, T.4
Farshy, C.5
Hanson, D.6
-
85
-
-
78650549662
-
Preexposure chemoprophylaxis for HIV prevention in men who have sex with men
-
Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587-99.
-
(2010)
N Engl J Med
, vol.363
, Issue.27
, pp. 2587-2599
-
-
Grant, R.M.1
Lama, J.R.2
Anderson, P.L.3
McMahan, V.4
Liu, A.Y.5
Vargas, L.6
-
86
-
-
84866283847
-
Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men
-
Anderson PL, Glidden DV, Liu A, Buchbinder S, Lama JR, Guanira JV, et al. Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men. Sci Transl Med. 2012;4(151):151ra25.
-
(2012)
Sci Transl Med
, vol.4
, Issue.151
-
-
Anderson, P.L.1
Glidden, D.V.2
Liu, A.3
Buchbinder, S.4
Lama, J.R.5
Guanira, J.V.6
-
87
-
-
84897452223
-
Strong relationship between oral dose and tenofovir hair levels in a randomized trial: Hair as a potential adherence measure for pre-exposure prophylaxis (PrEP)
-
Liu AY, Yang Q, Huang Y, Bacchetti P, Anderson PL, Jin C, et al. Strong relationship between oral dose and tenofovir hair levels in a randomized trial: hair as a potential adherence measure for pre-exposure prophylaxis (PrEP). PLoS One. 2014;9(1):e83736.
-
(2014)
PLoS One
, vol.9
, Issue.1
-
-
Liu, A.Y.1
Yang, Q.2
Huang, Y.3
Bacchetti, P.4
Anderson, P.L.5
Jin, C.6
-
88
-
-
0026700248
-
Identification of HIV-1 in semen following primary HIV-1 infection
-
Tindall B, Evans L, Cunningham P, McQueen P, Hurren L, Vasak E, et al. Identification of HIV-1 in semen following primary HIV-1 infection. AIDS. 1992;6(9):949-52.
-
(1992)
AIDS
, vol.6
, Issue.9
, pp. 949-952
-
-
Tindall, B.1
Evans, L.2
Cunningham, P.3
McQueen, P.4
Hurren, L.5
Vasak, E.6
-
89
-
-
0031040993
-
Shedding of HIV-1 in semen during primary infection [7]
-
Dyer JR, Gilliam BL, Eron JJ Jr, Cohen MS, Fiscus SA, Vernazza PL. Shedding of HIV-1 in semen during primary infection. AIDS. 1997;11(4):543-5. (Pubitemid 27113022)
-
(1997)
AIDS
, vol.11
, Issue.4
, pp. 543-545
-
-
Dyer, J.R.1
Gilliam, B.L.2
Eron Jr., J.J.3
Cohen, M.S.4
Fiscus, S.A.5
Vernazza, P.L.6
-
90
-
-
0029998895
-
Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission
-
Zhu T, Wang N, Carr A, Nam DS, Moor-Jankowski R, Cooper DA, et al. Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual transmission. J Virol. 1996;70(5):3098-107. (Pubitemid 26121927)
-
(1996)
Journal of Virology
, vol.70
, Issue.5
, pp. 3098-3107
-
-
Zhu, T.1
Wang, N.2
Carr, A.3
Nam, D.S.4
Moor-Jankowski, R.5
Cooper, D.A.6
Ho, D.D.7
-
91
-
-
0343145742
-
HIV-1 in semen: An isolated virus reservoir [1]
-
DOI 10.1016/S0140-6736(97)24042-0
-
Byrn RA, Zhang D, Eyre R, McGowan K, Kiessling AA. HIV-1 in semen: an isolated virus reservoir. Lancet. 1997;350(9085):1141. (Pubitemid 27454008)
-
(1997)
Lancet
, vol.350
, Issue.9085
, pp. 1141
-
-
Byrn, R.A.1
Zhang, D.2
Eyre, R.3
McGowan, K.4
Kiessling, A.A.5
-
92
-
-
0032558795
-
Resistance of HIV-1 to antiretroviral agents in blood and seminal plasma: Implications for transmission
-
Eron JJ, Vernazza PL, Johnston DM, Seillier-Moiseiwitsch F, Alcorn TM, Fiscus SA, et al. Resistance of HIV-1 to antiretroviral agents in blood and seminal plasma: implications for transmission. AIDS. 1998;12(15):F181-9. (Pubitemid 28479268)
-
(1998)
AIDS
, vol.12
, Issue.15
-
-
Eron, J.J.1
Vernazza, P.L.2
Johnston, D.M.3
Seillier-Moiseiwitsch, F.4
Alcorn, T.M.5
Fiscus, S.A.6
Cohen, M.S.7
-
93
-
-
0028146685
-
Detection and biologic characterization of infectious HIV-1 in semen of seropositive men
-
Vernazza PL, Eron JJ, Cohen MS, van der Horst CM, Troiani L, Fiscus SA. Detection and biologic characterization of infectious HIV-1 in semen of seropositive men. AIDS. 1994;8(9):1325-9. (Pubitemid 24267758)
-
(1994)
AIDS
, vol.8
, Issue.9
, pp. 1325-1329
-
-
Vernazza, P.L.1
Eron, J.J.2
Cohen, M.S.3
Van Der, H.C.M.4
Troiani, L.5
Fiscus, S.A.6
-
94
-
-
42449164708
-
Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV)
-
DOI 10.1089/aid.2007.0115
-
Diem K, Nickle DC, Motoshige A, Fox A, Ross S, Mullins JI, et al. Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV). AIDS Res Hum Retrovir. 2008;24(4):561-71. (Pubitemid 351571032)
-
(2008)
AIDS Research and Human Retroviruses
, vol.24
, Issue.4
, pp. 561-571
-
-
Diem, K.1
Nickle, D.C.2
Motoshige, A.3
Fox, A.4
Ross, S.5
Mullins, J.I.6
Corey, L.7
Coombs, R.W.8
Krieger, J.N.9
-
95
-
-
10644234595
-
Human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood: Compartmentalization and intrapatient recombination
-
DOI 10.1128/JVI.79.1.353-363.2005
-
Philpott S, Burger H, Tsoukas C, Foley B, Anastos K, Kitchen C, et al. Human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood: compartmentalization and intrapatient recombination. J Virol. 2005;79(1):353-63. (Pubitemid 39648389)
-
(2005)
Journal of Virology
, vol.79
, Issue.1
, pp. 353-363
-
-
Philpott, S.1
Burger, H.2
Tsoukas, C.3
Foley, B.4
Anastos, K.5
Kitchen, C.6
Weiser, B.7
-
96
-
-
33947212427
-
A new method to estimate quantitatively seminal vesicle and prostate gland contributions to ejaculate
-
DOI 10.1111/j.1365-2125.2006.02791.x
-
Ndovi TT, Parsons T, Choi L, Caffo B, Rohde C, Hendrix CW. A new method to estimate quantitatively seminal vesicle and prostate gland contributions to ejaculate. Br J Clin Pharmacol. 2007;63(4):404-20. (Pubitemid 46426637)
-
(2007)
British Journal of Clinical Pharmacology
, vol.63
, Issue.4
, pp. 404-420
-
-
Ndovi, T.T.1
Parsons, T.2
Choi, L.3
Caffo, B.4
Rohde, C.5
Hendrix, C.W.6
-
97
-
-
0034816333
-
Pharmacokinetic profiles of nevirapine and indinavir in various fractions of seminal plasma
-
DOI 10.1128/AAC.45.10.2902-2907.2001
-
van Praag RM, Repping S, de Vries JW, Lange JM, Hoetelmans RM, Prins JM. Pharmacokinetic profiles of nevirapine and indinavir in various fractions of seminal plasma. Antimicrob Agents Chemother. 2001;45(10):2902-7. (Pubitemid 32906690)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.10
, pp. 2902-2907
-
-
Van Praag, R.M.E.1
Repping, S.2
De Vries, J.W.A.3
Lange, J.M.A.4
Hoetelmans, R.M.W.5
Prins, J.M.6
-
98
-
-
39449137762
-
Male genital tract pharmacology: Developments in quantitative methods to better understand a complex peripheral compartment
-
DOI 10.1038/sj.clpt.6100342, PII 6100342
-
Cao YJ, Hendrix CW. Male genital tract pharmacology: developments in quantitative methods to better understand a complex peripheral compartment. Clin Pharmacol Ther. 2008;83(3):401-12. (Pubitemid 351272639)
-
(2008)
Clinical Pharmacology and Therapeutics
, vol.83
, Issue.3
, pp. 401-412
-
-
Cao, Y.-J.1
Hendrix, C.W.2
-
99
-
-
84987486315
-
The functional significance of the blood-testis barrier
-
Setchell BP. The functional significance of the blood-testis barrier. J Androl. 1980;1(1):3-10.
-
(1980)
J Androl
, vol.1
, Issue.1
, pp. 3-10
-
-
Setchell, B.P.1
-
100
-
-
79956267665
-
The blood-testis and blood-epididymis barriers are more than just their tight junctions
-
Mital P, Hinton BT, Dufour JM. The blood-testis and blood-epididymis barriers are more than just their tight junctions. Biol Reprod. 2011;84(5):851-8.
-
(2011)
Biol Reprod
, vol.84
, Issue.5
, pp. 851-858
-
-
Mital, P.1
Hinton, B.T.2
Dufour, J.M.3
-
101
-
-
0027367161
-
Barrier properties of testis microvessels
-
DOI 10.1073/pnas.90.23.11069
-
Holash JA, Harik SI, Perry G, Stewart PA. Barrier properties of testis microvessels. Proc Natl Acad Sci USA. 1993;90(23):11069-73. (Pubitemid 23354370)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 11069-11073
-
-
Holash, J.A.1
Harik, S.I.2
Perry, G.3
Stewart, P.A.4
-
102
-
-
4444310389
-
The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular tumours
-
DOI 10.1016/j.ejca.2004.05.010, PII S0959804904004149
-
Bart J, Hollema H, Groen HJ, de Vries EG, Hendrikse NH, Sleijfer DT, et al. The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular tumours. Eur J Cancer. 2004;40(14):2064-70. (Pubitemid 39165539)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.14
, pp. 2064-2070
-
-
Bart, J.1
Hollema, H.2
Groen, H.J.M.3
De Vries, E.G.E.4
Hendrikse, N.H.5
Sleijfer, D.T.6
Wegman, T.D.7
Vaalburg, W.8
Van Der, G.W.T.A.9
-
103
-
-
0343630779
-
Nucleoside analogues achieve high concentrations in seminal plasma: Relationship between drug concentration and virus burden
-
Pereira AS, Kashuba AD, Fiscus SA, Hall JE, Tidwell RR, Troiani L, et al. Nucleoside analogues achieve high concentrations in seminal plasma: relationship between drug concentration and virus burden. J Infect Dis. 1999;180(6):2039-43.
-
(1999)
J Infect Dis
, vol.180
, Issue.6
, pp. 2039-2043
-
-
Pereira, A.S.1
Kashuba, A.D.2
Fiscus, S.A.3
Hall, J.E.4
Tidwell, R.R.5
Troiani, L.6
-
104
-
-
0033838988
-
Semen and serum pharmacokinetics of zidovudine and zidovudine-glucuronide in men with HIV-1 infection
-
Anderson PL, Noormohamed SE, Henry K, Brundage RC, Balfour HH Jr, Fletcher CV. Semen and serum pharmacokinetics of zidovudine and zidovudine-glucuronide in men with HIV-1 infection. Pharmacotherapy. 2000;20(8):917-22. (Pubitemid 30659788)
-
(2000)
Pharmacotherapy
, vol.20
, Issue.8 I
, pp. 917-922
-
-
Anderson, P.L.1
Noormohamed, S.E.2
Henry, K.3
Brundage, R.C.4
Balfour Jr., H.H.5
Fletcher, C.V.6
-
105
-
-
0034622962
-
Concentrations of nevirapine, lamivudine and stavudine in semen of HIV-1-infected men
-
Taylor S, van Heeswijk RP, Hoetelmans RM, Workman J, Drake SM, White DJ, et al. Concentrations of nevirapine, lamivudine and stavudine in semen of HIV-1-infected men. AIDS. 2000;14(13):1979-84.
-
(2000)
AIDS
, vol.14
, Issue.13
, pp. 1979-1984
-
-
Taylor, S.1
Van Heeswijk, R.P.2
Hoetelmans, R.M.3
Workman, J.4
Drake, S.M.5
White, D.J.6
-
106
-
-
18044401251
-
Penetration of the nucleoside analogue abacavir into the genital tract of men infected with human immunodeficiency virus type 1
-
van Praag RM, van Heeswijk RP, Jurriaans S, Lange JM, Hoetelmans RM, Prins JM. Penetration of the nucleoside analogue abacavir into the genital tract of men infected with human immunodeficiency virus type 1. Clin Infect Dis. 2001;33(8):e91-2.
-
(2001)
Clin Infect Dis
, vol.33
, Issue.8
-
-
Van Praag, R.M.1
Van Heeswijk, R.P.2
Jurriaans, S.3
Lange, J.M.4
Hoetelmans, R.M.5
Prins, J.M.6
-
107
-
-
0037099162
-
The pharmacokinetics of amprenavir, zidovudine, and lamivudine in the genital tracts of men infected with human immunodeficiency virus type 1 (AIDS Clinical Trials Group Study 850)
-
DOI 10.1086/341209
-
Pereira AS, Smeaton LM, Gerber JG, Acosta EP, Snyder S, Fiscus SA, et al. The pharmacokinetics of amprenavir, zidovudine, and lamivudine in the genital tracts of men infected with human immunodeficiency virus type 1 (AIDS Clinical Trials Group study 850). J Infect Dis. 2002;186(2):198-204. (Pubitemid 34765507)
-
(2002)
Journal of Infectious Diseases
, vol.186
, Issue.2
, pp. 198-204
-
-
Pereira, A.S.1
Smeaton, L.M.2
Gerber, J.G.3
Acosta, E.P.4
Snyder, S.5
Fiscus, S.A.6
Tidwell, R.R.7
Gulick, R.M.8
Murphy, R.L.9
Eron Jr., J.J.10
-
108
-
-
4744357409
-
Penetration of enfuvirtide, tenofovir, efavirenz, and protease inhibitors in the genital tract of HIV-1-infected men
-
DOI 10.1097/00002030-200409240-00014
-
Ghosn J, Chaix ML, Peytavin G, Rey E, Bresson JL, Goujard C, et al. Penetration of enfuvirtide, tenofovir, efavirenz, and protease inhibitors in the genital tract of HIV-1-infected men. AIDS. 2004;18(14):1958-61. (Pubitemid 39313214)
-
(2004)
AIDS
, vol.18
, Issue.14
, pp. 1958-1961
-
-
Ghosn, J.1
Chaix, M.-L.2
Peytavin, G.3
Rey, E.4
Bresson, J.-L.5
Goujard, C.6
Katlama, C.7
Viard, J.-P.8
Treluyer, J.-M.9
Rouzioux, C.10
-
109
-
-
33749183743
-
Penetration of didanosine in semen of HIV-1-infected men
-
DOI 10.1093/jac/dkl111
-
Cruciani M, Liuzzi G, Chirianni A, Audagnotto S, Bonora S, Di Biagio A, et al. Penetration of didanosine in semen of HIV-1-infected men. J Antimicrob Chemother. 2006;57(6):1244-7. (Pubitemid 44644435)
-
(2006)
Journal of Antimicrobial Chemotherapy
, vol.57
, Issue.6
, pp. 1244-1247
-
-
Cruciani, M.1
Liuzzi, G.2
Chirianni, A.3
Audagnotto, S.4
Bonora, S.5
Di, B.A.6
Sinicco, A.7
Bassetti, M.8
Gatti, G.9
-
110
-
-
46449107370
-
Differential extracellular and intracellular concentrations of zidovudine and lamivudine in semen and plasma of HIV-1-infected men
-
Dumond JB, Reddy YS, Troiani L, Rodriguez JF, Bridges AS, Fiscus SA, et al. Differential extracellular and intracellular concentrations of zidovudine and lamivudine in semen and plasma of HIV-1-infected men. J Acquir Immune Defic Syndr. 2008;48(2):156-62.
-
(2008)
J Acquir Immune Defic Syndr
, vol.48
, Issue.2
, pp. 156-162
-
-
Dumond, J.B.1
Reddy, Y.S.2
Troiani, L.3
Rodriguez, J.F.4
Bridges, A.S.5
Fiscus, S.A.6
-
111
-
-
42449158135
-
The pharmacokinetics and viral activity of tenofovir in the male genital tract
-
DOI 10.1097/QAI.0b013e3181632cc3, PII 0012633420080301000009
-
Vourvahis M, Tappouni HL, Patterson KB, Chen YC, Rezk NL, Fiscus SA, et al. The pharmacokinetics and viral activity of tenofovir in the male genital tract. J Acquir Immune Defic Syndr. 2008;47(3):329-33. (Pubitemid 351619418)
-
(2008)
Journal of Acquired Immune Deficiency Syndromes
, vol.47
, Issue.3
, pp. 329-333
-
-
Vourvahis, M.1
Tappouni, H.L.2
Patterson, K.B.3
Chen, Y.-C.4
Rezk, N.L.5
Fiscus, S.A.6
Kearney, B.P.7
Rooney, J.F.8
Hui, J.9
Cohen, M.S.10
Kashuba, A.D.M.11
-
112
-
-
84872848368
-
Pharmacokinetics of maraviroc, raltegravir, darunavir, and etravirine in the semen of HIV-infected men
-
Antoniou T, Hasan S, Loutfy MR, Kovacs C, Brunetta J, Smith G, et al. Pharmacokinetics of maraviroc, raltegravir, darunavir, and etravirine in the semen of HIV-infected men. J Acquir Immune Defic Syndr. 2013;62(2):e58-60.
-
(2013)
J Acquir Immune Defic Syndr
, vol.62
, Issue.2
-
-
Antoniou, T.1
Hasan, S.2
Loutfy, M.R.3
Kovacs, C.4
Brunetta, J.5
Smith, G.6
-
113
-
-
75749115111
-
High concentration of raltegravir in semen of HIV-infected men: Results from a substudy of the EASIER-ANRS 138 trial
-
Barau C, Delaugerre C, Braun J, de Castro N, Furlan V, Charreau I, et al. High concentration of raltegravir in semen of HIV-infected men: results from a substudy of the EASIER-ANRS 138 trial. Antimicrob Agents Chemother. 2010;54(2):937-9.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.2
, pp. 937-939
-
-
Barau, C.1
Delaugerre, C.2
Braun, J.3
De Castro, N.4
Furlan, V.5
Charreau, I.6
-
114
-
-
77952600233
-
Raltegravir penetration in seminal plasma of healthy volunteers
-
Calcagno A, Bonora S, D'Avolio A, Siccardi M, Simiele M, Chiesa M, et al. Raltegravir penetration in seminal plasma of healthy volunteers. Antimicrob Agents Chemother. 2010;54(6):2744-5.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.6
, pp. 2744-2745
-
-
Calcagno, A.1
Bonora, S.2
D'Avolio, A.3
Siccardi, M.4
Simiele, M.5
Chiesa, M.6
-
115
-
-
84920127504
-
Pharmacokinetics of raltegravir in the semen of HIV-infected men
-
Epub 2014 Feb 12. doi:10.3851/IMP2750
-
Antoniou T, Loutfy MR, Brunetta J, Smith G, Halpenny R, la Porte C. Pharmacokinetics of raltegravir in the semen of HIV-infected men. Antivir Ther. Epub 2014 Feb 12. doi:10.3851/IMP2750.
-
Antivir Ther
-
-
Antoniou, T.1
Loutfy, M.R.2
Brunetta, J.3
Smith, G.4
Halpenny, R.5
La Porte, C.6
-
117
-
-
0037377825
-
HIV-1 RNA levels, resistance, and drug diffusion in semen versus blood in patients receiving a lopinavir-containing regimen [1]
-
DOI 10.1097/00126334-200304010-00018
-
Lafeuillade A, Solas C, Chadapaud S, Hittinger G, Poggi C, Lacarelle B. HIV-1 RNA levels, resistance, and drug diffusion in semen versus blood in patients receiving a lopinavir-containing regimen. J Acquir Immune Defic Syndr. 2003;32(4):462-4. (Pubitemid 36363162)
-
(2003)
Journal of Acquired Immune Deficiency Syndromes
, vol.32
, Issue.4
, pp. 462-464
-
-
Lafeuillade, A.1
Solas, C.2
Chadapaud, S.3
Hittinger, G.4
Poggi, C.5
Lacarelle, B.6
-
118
-
-
0037119029
-
Limited penetration of lopinavir into seminal plasma of HIV-1-infected men [5]
-
DOI 10.1097/00002030-200208160-00023
-
Sankatsing SU, Droste J, Burger D, Van Praag RM, Jurriaans S, Lange JM, et al. Limited penetration of lopinavir into seminal plasma of HIV-1-infected men. AIDS. 2002;16(12):1698-700. (Pubitemid 34921122)
-
(2002)
AIDS
, vol.16
, Issue.12
, pp. 1698-1700
-
-
Sankatsing, S.U.C.1
Droste, J.2
Burger, D.3
Van Praag, R.M.E.4
Jurriaans, S.5
Lange, J.M.A.6
Prins, J.M.7
-
119
-
-
0034801618
-
Antiretroviral drug concentrations in semen of HIV-infected men: Differential penetration of indinavir, ritonavir and saquinavir
-
Taylor S, Back DJ, Drake SM, Workman J, Reynolds H, Gibbons SE, et al. Antiretroviral drug concentrations in semen of HIV-infected men: differential penetration of indinavir, ritonavir and saquinavir. J Antimicrob Chemother. 2001;48(3):351-4. (Pubitemid 32898804)
-
(2001)
Journal of Antimicrobial Chemotherapy
, vol.48
, Issue.3
, pp. 351-354
-
-
Taylor, S.1
Backc, D.J.2
Drake, S.M.3
Workman, J.4
Reynolds, H.5
Gibbons, S.E.6
White, D.J.7
Pillay, D.8
-
120
-
-
0032903015
-
Poor penetration of the male genital tract by HIV-1 protease inhibitors [1]
-
DOI 10.1097/00002030-199905070-00017
-
Taylor S, Back DJ, Workman J, Drake SM, White DJ, Choudhury B, et al. Poor penetration of the male genital tract by HIV-1 protease inhibitors. AIDS. 1999;13(7):859-60. (Pubitemid 29224590)
-
(1999)
AIDS
, vol.13
, Issue.7
, pp. 859-860
-
-
Taylor, S.1
Back, D.J.2
Workman, J.3
Drake, S.M.4
White, D.J.5
Choudhury, B.6
Cane, P.A.7
Beards, G.M.8
Halifax, K.9
Pillay, D.10
-
121
-
-
78549287438
-
Darunavir concentrations exceed the protein-corrected EC(5)(0) for wild-type HIV in the semen of HIV-1-infected men
-
Taylor S, Jayasuriya AN, Berry A, Gilleran G, Dufty NE, Else L, et al. Darunavir concentrations exceed the protein-corrected EC(5)(0) for wild-type HIV in the semen of HIV-1-infected men. AIDS. 2010;24(16):2583-7.
-
(2010)
AIDS
, vol.24
, Issue.16
, pp. 2583-2587
-
-
Taylor, S.1
Jayasuriya, A.N.2
Berry, A.3
Gilleran, G.4
Dufty, N.E.5
Else, L.6
-
122
-
-
33846010192
-
Penetration of atazanavir in seminal plasma of men infected with human immunodeficiency virus type 1
-
DOI 10.1128/AAC.00774-06
-
van Leeuwen E, Ter Heine R, van der Veen F, Repping S, Beijnen JH, Prins JM. Penetration of atazanavir in seminal plasma of men infected with human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2007;51(1):335-7. (Pubitemid 46047724)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.1
, pp. 335-337
-
-
Van Leeuwen, E.1
Ter, H.R.2
Van Der, V.F.3
Repping, S.4
Beijnen, J.H.5
Prins, J.M.6
-
123
-
-
33748146444
-
Limited penetration of lopinavir and ritonavir in the genital tract of men infected with HIV-1 in Brazil
-
DOI 10.1097/01.ftd.0000180225.27008.8c, PII 0000769120060400000005
-
Vergara TR, Estrela RC, Suarez-Kurtz G, Schechter M, Cerbino-Neto J, Barroso PF. Limited penetration of lopinavir and ritonavir in the genital tract of men infected with HIV-1 in Brazil. Ther Drug Monit. 2006;28(2):175-9. (Pubitemid 44314945)
-
(2006)
Therapeutic Drug Monitoring
, vol.28
, Issue.2
, pp. 175-179
-
-
Vergara, T.R.C.1
Estrela, R.C.E.2
Suarez-Kurtz, G.3
Schechter, M.4
Cerbino-Neto, J.5
Barroso, P.F.6
-
124
-
-
0037105750
-
Effects of formulation and dosing strategy on amprenavir concentrations in the seminal plasma of human immunodeficiency virus type 1-infected men
-
DOI 10.1086/342389
-
Chaudry NI, Eron JJ, Naderer OJ, Pereira AS, Wire MB, Fiscus SA, et al. Effects of formulation and dosing strategy on amprenavir concentrations in the seminal plasma of human immunodeficiency virus type 1-infected men. Clin Infect Dis. 2002;35(6):760-2. (Pubitemid 35024739)
-
(2002)
Clinical Infectious Diseases
, vol.35
, Issue.6
, pp. 760-762
-
-
Chaudry, N.I.1
Eron, J.J.2
Naderer, O.J.3
Pereira, A.S.4
Wire, M.B.5
Fiscus, S.A.6
Kashuba, A.D.M.7
-
125
-
-
0036838801
-
Pharmacokinetic and pharmacodynamic investigation of efavirenz in the semen and blood of human immunodeficiency virus type 1-infected men
-
DOI 10.1086/344311
-
Reddy YS, Gotzkowsky SK, Eron JJ, Kim JY, Fiske WD, Fiscus SA, et al. Pharmacokinetic and pharmacodynamic investigation of efavirenz in the semen and blood of human immunodeficiency virus type 1-infected men. J Infect Dis. 2002;186(9):1339-43. (Pubitemid 35193014)
-
(2002)
Journal of Infectious Diseases
, vol.186
, Issue.9
, pp. 1339-1343
-
-
Reddy, Y.S.1
Gotzkowsky, S.K.2
Eron, J.J.3
Kim, J.Y.4
Fiske, W.D.5
Fiscus, S.A.6
Petch, L.7
Cohen, M.S.8
Kashuba, A.D.M.9
-
126
-
-
0035914039
-
Penetration of efavirenz into the male genital tract: Drug concentrations and antiviral activity in semen and blood of HIV-1-infected men
-
DOI 10.1097/00002030-200110190-00022
-
Taylor S, Reynolds H, Sabin CA, Drake SM, White DJ, Back DJ, et al. Penetration of efavirenz into the male genital tract: drug concentrations and antiviral activity in semen and blood of HIV-1-infected men. AIDS. 2001;15(15):2051-3. (Pubitemid 32980652)
-
(2001)
AIDS
, vol.15
, Issue.15
, pp. 2051-2053
-
-
Taylor, S.1
Reynolds, H.2
Sabin, C.A.3
Drake, S.M.4
White, D.J.5
Back, D.J.6
Pillay, D.7
-
127
-
-
79959378687
-
The male genital tract is not a pharmacological sanctuary from efavirenz
-
Avery LB, Bakshi RP, Cao YJ, Hendrix CW. The male genital tract is not a pharmacological sanctuary from efavirenz. Clin Pharmacol Ther. 2011;90(1):151-6.
-
(2011)
Clin Pharmacol Ther
, vol.90
, Issue.1
, pp. 151-156
-
-
Avery, L.B.1
Bakshi, R.P.2
Cao, Y.J.3
Hendrix, C.W.4
-
128
-
-
0030791369
-
Effect of antiviral treatment on the shedding of HIV-1 in semen
-
DOI 10.1097/00002030-199710000-00008
-
Vernazza PL, Gilliam BL, Flepp M, Dyer JR, Frank AC, Fiscus SA, et al. Effect of antiviral treatment on the shedding of HIV-1 in semen. AIDS. 1997;11(10):1249-54. (Pubitemid 27298091)
-
(1997)
AIDS
, vol.11
, Issue.10
, pp. 1249-1254
-
-
Vernazza, P.L.1
Gilliam, B.L.2
Flepp, M.3
Dyer, J.R.4
Frank, A.C.5
Fiscus, S.A.6
Cohen, M.S.7
Eron, J.J.8
-
129
-
-
0005433724
-
Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV
-
DOI 10.1097/00002030-200001280-00006
-
Vernazza PL, Troiani L, Flepp MJ, Cone RW, Schock J, Roth F, et al. Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV. The Swiss HIV Cohort Study. AIDS. 2000;14(2):117-21. (Pubitemid 30116436)
-
(2000)
AIDS
, vol.14
, Issue.2
, pp. 117-121
-
-
Vernazza, P.L.1
Troiani, L.2
Flepp, M.J.3
Cone, R.W.4
Schock, J.5
Roth, F.6
Boggian, K.7
Cohen, M.S.8
Fiscus, S.A.9
Eron, J.J.10
-
130
-
-
0035970644
-
Viral burden in genital secretions determines male-to-female sexual transmission of HIV-1: A probabilistic empiric model
-
DOI 10.1097/00002030-200103300-00012
-
Chakraborty H, Sen PK, Helms RW, Vernazza PL, Fiscus SA, Eron JJ, et al. Viral burden in genital secretions determines male-to-female sexual transmission of HIV-1: a probabilistic empiric model. AIDS. 2001;15(5):621-7. (Pubitemid 32281358)
-
(2001)
AIDS
, vol.15
, Issue.5
, pp. 621-627
-
-
Chakraborty, H.1
Sen, P.K.2
Helms, R.W.3
Vernazza, P.L.4
Fiscus, S.A.5
Eron, J.J.6
Patterson, B.K.7
Coombs, R.W.8
Krieger, J.N.9
Cohen, M.S.10
-
131
-
-
84931266584
-
Cheminformatics analysis to identify predictors of antiviral drug penetration into the female genital tract
-
Epub 2014 Feb 10
-
Thompson C, Sedykh A, Nicol M, Muratov E, Fourches D, Tropsha A, et al. Cheminformatics analysis to identify predictors of antiviral drug penetration into the female genital tract. AIDS Res Hum Retrovir. [Epub 2014 Feb 10].
-
AIDS Res Hum Retrovir
-
-
Thompson, C.1
Sedykh, A.2
Nicol, M.3
Muratov, E.4
Fourches, D.5
Tropsha, A.6
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