Strong relationship between oral dose and tenofovir hair levels in a randomized trial: Hair as a potential adherence measure for pre-exposure prophylaxis (PrEP)

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Liu, Albert Y ^a,b   Yang, Qiyun ^b   Huang, Yong ^b   Bacchetti, Peter ^b   Anderson, Peter L ^c   Jin, Chengshi ^b   Goggin, Kathy ^d   Stojanovski, Kristefer ^a   Grant, Robert ^e   Buchbinder, Susan P ^a,b   Greenblatt, Ruth M ^b,f   Gandhi, Monica ^b  

^a SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^e GLADSTONE INSTITUTES   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TENOFOVIR;

ADULT; ALLERGIC REACTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIRECTLY OBSERVED THERAPY; DRUG HAIR LEVEL; DRUG WITHDRAWAL; FATIGUE; FEMALE; FLATULENCE; HEADACHE; HUMAN; HUMAN EXPERIMENT; LOOSE FECES; MALE; MAXIMUM PLASMA CONCENTRATION; MEDICATION COMPLIANCE; NAUSEA; NORMAL HUMAN; OPEN STUDY; PATIENT COMPLIANCE; PHASE 1 CLINICAL TRIAL; PRE EXPOSURE PROPHYLAXIS; PROPHYLAXIS; PRURITUS; RANDOMIZED CONTROLLED TRIAL; TONGUE DISEASE; TONGUE TINGLING; UNSPECIFIED SIDE EFFECT; UPPER RESPIRATORY TRACT INFECTION; URTICARIA;

ADENINE; ADMINISTRATION, ORAL; ADULT; DEMOGRAPHY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HAIR; HIV INFECTIONS; HUMANS; MALE; MEDICATION ADHERENCE; ORGANOPHOSPHONATES;

EID: 84897452223     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083736     Document Type: Article

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