Penetration of efavirenz into the male genital tract: Drug concentrations and antiviral activity in semen and blood of HIV-1-infected men

AIDS

Volumn 15, Issue 15, 2001, Pages 2051-2053

  Taylor, Stephen ^a,b   Reynolds, Helen ^c   Sabin, Caroline A ^d   Drake, Susan M ^b   White, David J ^b   Back, David J ^c   Pillay, Deenan ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; EFAVIRENZ;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG BLOOD LEVEL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE GENITAL SYSTEM; PRIORITY JOURNAL; SEMINAL PLASMA; TREATMENT PLANNING; VIRUS LOAD;

EID: 0035914039     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200110190-00022     Document Type: Article

References (5)

1. Concentrations of nevirapine, lamivudine and stavudine in semen of HIV-1-infected men
2. Population pharmacokinetics of efavirenz in phase Ii studies and relationship with efficacy
3. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1 infected patients
4. Penetration of efavirenz into the male genital tract as measured by seminal plasma to blood plasma concentration and AUC 24 h ratios
5. Antiretroviral drug concentrations in semen of HIV-1 infected men