메뉴 건너뛰기




Volumn 123, Issue 20, 2014, Pages 3080-3088

Erythro-megakaryocytic transcription factors associated with hereditary anemia

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; GLOBIN; GROWTH FACTOR INDEPENDENT 1 BETA; HEMOGLOBIN; HEMOGLOBIN F; MEMBRANE PROTEIN; MUTANT PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 84903175117     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-01-453167     Document Type: Review
Times cited : (53)

References (112)
  • 1
    • 50949090908 scopus 로고    scopus 로고
    • EKLF restricts megakaryocytic differentiation at the benefit of erythrocytic differentiation
    • Bouilloux F, Juban G, Cohet N, et al. EKLF restricts megakaryocytic differentiation at the benefit of erythrocytic differentiation. Blood. 2008;112(3):576-584.
    • (2008) Blood , vol.112 , Issue.3 , pp. 576-584
    • Bouilloux, F.1    Juban, G.2    Cohet, N.3
  • 3
    • 84887325599 scopus 로고    scopus 로고
    • Congenital dyserythropoietic anemias: Molecular insights and diagnostic approach
    • Iolascon A, Heimpel H, Wahlin A, Tamary H. Congenital dyserythropoietic anemias: molecular insights and diagnostic approach. Blood. 2013;122(13):2162- 2166.
    • (2013) Blood , vol.122 , Issue.13 , pp. 2162-2166
    • Iolascon, A.1    Heimpel, H.2    Wahlin, A.3    Tamary, H.4
  • 4
    • 84883649384 scopus 로고    scopus 로고
    • Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I
    • WGS500 Consortium
    • Babbs C, Roberts NA, Sanchez-Pulido L, et al; WGS500 Consortium. Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I. Haematologica. 2013;98(9):1383-1387.
    • (2013) Haematologica , vol.98 , Issue.9 , pp. 1383-1387
    • Babbs, C.1    Roberts, N.A.2    Sanchez-Pulido, L.3
  • 5
    • 84859894479 scopus 로고    scopus 로고
    • Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply
    • Ask K, Jasencakova Z, Menard P, Feng Y, Almouzni G, Groth A. Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply. EMBO J. 2012;31(8):2013-2023.
    • (2012) EMBO J , vol.31 , Issue.8 , pp. 2013-2023
    • Ask, K.1    Jasencakova, Z.2    Menard, P.3    Feng, Y.4    Almouzni, G.5    Groth, A.6
  • 6
    • 79959496006 scopus 로고    scopus 로고
    • Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1alpha localization in erythroblasts
    • Renella R, Roberts NA, Brown JM, et al. Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1alpha localization in erythroblasts. Blood. 2011;117(25):6928-6938.
    • (2011) Blood , vol.117 , Issue.25 , pp. 6928-6938
    • Renella, R.1    Roberts, N.A.2    Brown, J.M.3
  • 7
    • 84869094254 scopus 로고    scopus 로고
    • Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia
    • Horos R, von Lindern M. Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia. Br J Haematol. 2012;159(5):514-527.
    • (2012) Br J Haematol , vol.159 , Issue.5 , pp. 514-527
    • Horos, R.1    Von Lindern, M.2
  • 8
    • 84863554398 scopus 로고    scopus 로고
    • Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia
    • Sankaran VG, Ghazvinian R, Do R, et al. Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. J Clin Invest. 2012;122(7):2439-2443.
    • (2012) J Clin Invest , vol.122 , Issue.7 , pp. 2439-2443
    • Sankaran, V.G.1    Ghazvinian, R.2    Do, R.3
  • 9
    • 84878995335 scopus 로고    scopus 로고
    • The molecular basis of β-thalassemia
    • Thein SL. The molecular basis of β-thalassemia. Cold Spring Harb Perspect Med. 2013;3(5):a011700.
    • (2013) Cold Spring Harb Perspect Med , vol.3 , Issue.5
    • Thein, S.L.1
  • 10
    • 12344325677 scopus 로고    scopus 로고
    • GATA1 in normal and malignant hematopoiesis
    • DOI 10.1016/j.semcdb.2004.11.002, PII S1084952104001041, Protein Synthesis in Health and Disease
    • Crispino JD. GATA1 in normal and malignant hematopoiesis. Semin Cell Dev Biol. 2005;16(1):137-147. (Pubitemid 40126884)
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , Issue.1 , pp. 137-147
    • Crispino, J.D.1
  • 11
    • 0025203886 scopus 로고
    • Transcriptional activation and DNA binding by the erythroid factor GF-1/ NF-E1/Eryf 1
    • Martin DI, Orkin SH. Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1. Genes Dev. 1990;4(11):1886-1898. (Pubitemid 120012590)
    • (1990) Genes and Development , vol.4 , Issue.11 , pp. 1886-1898
    • Martin, D.I.K.1    Orkin, S.H.2
  • 12
    • 0029863093 scopus 로고    scopus 로고
    • A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction
    • Trainor CD, Omichinski JG, Vandergon TL, Gronenborn AM, Clore GM, Felsenfeld G. A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction. Mol Cell Biol. 1996;16(5):2238-2247. (Pubitemid 26123744)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.5 , pp. 2238-2247
    • Trainor, C.D.1    Omichinski, J.G.2    Vandergon, T.L.3    Gronenborn, A.M.4    Clore, G.M.5    Felsenfeld, G.6
  • 13
    • 0031472234 scopus 로고    scopus 로고
    • FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
    • DOI 10.1016/S0092-8674(00)80318-9
    • Tsang AP, Visvader JE, Turner CA, et al. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell. 1997;90(1):109-119. (Pubitemid 28009423)
    • (1997) Cell , vol.90 , Issue.1 , pp. 109-119
    • Tsang, A.P.1    Visvader, J.E.2    Turner, C.A.3    Fujiwara, Y.4    Channing, Y.5    Weiss, M.J.6    Crossley, M.7    Orkin, S.H.8
  • 15
    • 0033083804 scopus 로고    scopus 로고
    • Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: The GATA-1:FOG complex
    • DOI 10.1016/S1097-2765(00)80312-3
    • Crispino JD, Lodish MB, MacKay JP, Orkin SH. Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1:FOG complex. Mol Cell. 1999;3(2):219-228. (Pubitemid 29292622)
    • (1999) Molecular Cell , vol.3 , Issue.2 , pp. 219-228
    • Crispino, J.D.1    Lodish, M.B.2    MacKay, J.P.3    Orkin, S.H.4
  • 16
    • 23844457607 scopus 로고    scopus 로고
    • Dyserythropoietic anemia and thrombocytopenia due to a novel mutation in GATA-1
    • DOI 10.1159/000086586
    • Del Vecchio GC, Giordani L, De Santis A, De Mattia D. Dyserythropoietic anemia and thrombocytopenia due to a novel mutation in GATA-1. Acta Haematol. 2005;114(2):113-116. (Pubitemid 41160941)
    • (2005) Acta Haematologica , vol.114 , Issue.2 , pp. 113-116
    • Del, V.G.C.1    Giordani, L.2    De Santis, A.3    De Mattia, D.4
  • 18
    • 33947223723 scopus 로고    scopus 로고
    • Congenital erythropoietic porphyria due to a mutation in GATA1: The first trans-acting mutation causative for a human porphyria
    • DOI 10.1182/blood-2006-06-022848
    • Phillips JD, Steensma DP, Pulsipher MA, Spangrude GJ, Kushner JP. Congenital erythropoietic porphyria due to a mutation in GATA1: the first trans-acting mutation causative for a human porphyria. Blood. 2007;109(6):2618-2621. (Pubitemid 46425911)
    • (2007) Blood , vol.109 , Issue.6 , pp. 2618-2621
    • Phillips, J.D.1    Steensma, D.P.2    Pulsipher, M.A.3    Spangrude, G.J.4    Kushner, J.P.5
  • 19
    • 39149123486 scopus 로고    scopus 로고
    • G208R germline mutation [4]
    • DOI 10.1038/sj.leu.2404904, PII 2404904
    • Kratz CP, Niemeyer CM, Karow A, Volz-Fleckenstein M, Schmitt-Gräff A, Strahm B. Congenital transfusion-dependent anemia and thrombocytopenia with myelodysplasia due to a recurrent GATA1(G208R) germline mutation. Leukemia. 2008;22(2):432-434. (Pubitemid 351250551)
    • (2008) Leukemia , vol.22 , Issue.2 , pp. 432-434
    • Kratz, C.P.1    Niemeyer, C.M.2    Karow, A.3    Volz-Fleckenstein, M.4    Schmitt-Graff, A.5    Strahm, B.6
  • 20
    • 84884190615 scopus 로고    scopus 로고
    • Analysis of disease-causing GATA1 mutations in murine gene complementation systems
    • Campbell AE, Wilkinson-White L, Mackay JP, Matthews JM, Blobel GA. Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood. 2013;121(26):5218-5227.
    • (2013) Blood , vol.121 , Issue.26 , pp. 5218-5227
    • Campbell, A.E.1    Wilkinson-White, L.2    Mackay, J.P.3    Matthews, J.M.4    Blobel, G.A.5
  • 21
    • 84875054519 scopus 로고    scopus 로고
    • A novel GATA1 mutation (Stop414Arg) in a family with the rare X-linked blood group Lu(a-b-) phenotype and mild macrothrombocytic thrombocytopenia
    • Singleton BK, Roxby DJ, Stirling JW, et al. A novel GATA1 mutation (Stop414Arg) in a family with the rare X-linked blood group Lu(a-b-) phenotype and mild macrothrombocytic thrombocytopenia. Br J Haematol. 2013;161(1):139-142.
    • (2013) Br J Haematol , vol.161 , Issue.1 , pp. 139-142
    • Singleton, B.K.1    Roxby, D.J.2    Stirling, J.W.3
  • 22
    • 83255185464 scopus 로고    scopus 로고
    • Myeloid leukemia in Down syndrome
    • Khan I, Malinge S, Crispino J. Myeloid leukemia in Down syndrome. Crit Rev Oncog. 2011;16(1-2):25-36.
    • (2011) Crit Rev Oncog , vol.16 , Issue.1-2 , pp. 25-36
    • Khan, I.1    Malinge, S.2    Crispino, J.3
  • 24
    • 84899666581 scopus 로고    scopus 로고
    • Loss of GATA-1 full length as a cause of Diamond-Blackfan anemia phenotype
    • published online ahead of print January 22, 2014
    • Parrella SAA, Aspesi A, Quarello P, et al. Loss of GATA-1 full length as a cause of Diamond-Blackfan anemia phenotype [published online ahead of print January 22, 2014]. Pediatr Blood Cancer.
    • Pediatr Blood Cancer
    • Parrella, S.A.A.1    Aspesi, A.2    Quarello, P.3
  • 26
    • 0029001881 scopus 로고
    • Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals
    • Tournamille C, Colin Y, Cartron JP, Le Van Kim C. Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals. Nat Genet. 1995;10(2):224-228.
    • (1995) Nat Genet , vol.10 , Issue.2 , pp. 224-228
    • Tournamille, C.1    Colin, Y.2    Cartron, J.P.3    Le Van Kim, C.4
  • 27
    • 84896828347 scopus 로고    scopus 로고
    • X-linked sideroblastic anemia due to ALAS2 intron 1 enhancer element GATA binding site mutations
    • Campagna DR, de Bie CI, Schmitz-Abe K, et al. X-linked sideroblastic anemia due to ALAS2 intron 1 enhancer element GATA binding site mutations. Am J Hematol. 2013;89(3):315-319.
    • (2013) Am J Hematol , vol.89 , Issue.3 , pp. 315-319
    • Campagna, D.R.1    De Bie, C.I.2    Schmitz-Abe, K.3
  • 28
    • 84896689530 scopus 로고    scopus 로고
    • Identification of the novel erythroid-specific enhancer for ALAS2 gene and its loss-offunction mutation associated with congenital sideroblastic anemia
    • Kaneko K, Furuyama K, Fujiwara T, et al. Identification of the novel erythroid-specific enhancer for ALAS2 gene and its loss-offunction mutation associated with congenital sideroblastic anemia. Haematologica. 2014;99(20):252-261.
    • (2014) Haematologica , vol.99 , Issue.20 , pp. 252-261
    • Kaneko, K.1    Furuyama, K.2    Fujiwara, T.3
  • 29
    • 0035103547 scopus 로고    scopus 로고
    • Uroporphyrinogen III synthase erythroid promoter mutations in adjacent GATA1 and CP2 elements cause congenital erythropoietic porphyria
    • Solis C, Aizencang GI, Astrin KH, Bishop DF, Desnick RJ. Uroporphyrinogen III synthase erythroid promoter mutations in adjacent GATA1 and CP2 elements cause congenital erythropoietic porphyria. J Clin Invest. 2001;107(6):753-762. (Pubitemid 32225361)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.6 , pp. 753-762
    • Solis, C.1    Aizencang, G.I.2    Astrin, K.H.3    Bishop, D.F.4    Desnick, R.J.5
  • 31
    • 70449638281 scopus 로고    scopus 로고
    • Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis
    • Yu M, Riva L, Xie H, et al. Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol Cell. 2009;36(4):682-695.
    • (2009) Mol Cell , vol.36 , Issue.4 , pp. 682-695
    • Yu, M.1    Riva, L.2    Xie, H.3
  • 32
    • 70449696134 scopus 로고    scopus 로고
    • Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression
    • Cheng Y, Wu W, Kumar SA, et al. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res. 2009;19(12):2172-2184.
    • (2009) Genome Res , vol.19 , Issue.12 , pp. 2172-2184
    • Cheng, Y.1    Wu, W.2    Kumar, S.A.3
  • 33
    • 70449675049 scopus 로고    scopus 로고
    • Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy
    • Fujiwara T, O'Geen H, Keles S, et al. Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell. 2009;36(4):667-681.
    • (2009) Mol Cell , vol.36 , Issue.4 , pp. 667-681
    • Fujiwara, T.1    O'Geen, H.2    Keles, S.3
  • 34
    • 20044381309 scopus 로고    scopus 로고
    • Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1
    • DOI 10.1038/ng1566
    • Li Z, Godinho FJ, Klusmann JH, Garriga-Canut M, Yu C, Orkin SH. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet. 2005;37(6):613-619. (Pubitemid 40770416)
    • (2005) Nature Genetics , vol.37 , Issue.6 , pp. 613-619
    • Li, Z.1    Godinho, F.J.2    Klusmann, J.-H.3    Garriga-Canut, M.4    Yu, C.5    Orkin, S.H.6
  • 35
    • 0035903475 scopus 로고    scopus 로고
    • In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis
    • DOI 10.1093/emboj/20.18.5250
    • Shimizu R, Takahashi S, Ohneda K, Engel JD, Yamamoto M. In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis. EMBO J. 2001;20(18):5250-5260. (Pubitemid 32910919)
    • (2001) EMBO Journal , vol.20 , Issue.18 , pp. 5250-5260
    • Shimizu, R.1    Takahashi, S.2    Ohneda, K.3    Engel, J.D.4    Yamamoto, M.5
  • 36
    • 77954071946 scopus 로고    scopus 로고
    • Gfi1-cells and circuits: Unraveling transcriptional networks of development and disease
    • Phelan JD, Shroyer NF, Cook T, Gebelein B, Grimes HL. Gfi1-cells and circuits: unraveling transcriptional networks of development and disease. Curr Opin Hematol. 2010;17(4):300-307.
    • (2010) Curr Opin Hematol , vol.17 , Issue.4 , pp. 300-307
    • Phelan, J.D.1    Shroyer, N.F.2    Cook, T.3    Gebelein, B.4    Grimes, H.L.5
  • 39
    • 0036467868 scopus 로고    scopus 로고
    • The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages
    • DOI 10.1101/gad.959102
    • Saleque S, Cameron S, Orkin SH. The zincfinger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages. Genes Dev. 2002;16(3):301-306. (Pubitemid 34111410)
    • (2002) Genes and Development , vol.16 , Issue.3 , pp. 301-306
    • Saleque, S.1    Cameron, S.2    Orkin, S.H.3
  • 40
    • 77950986252 scopus 로고    scopus 로고
    • Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage
    • Randrianarison-Huetz V, Laurent B, Bardet V, Blobe GC, Huetz F, Duménil D. Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage. Blood. 2010;115(14):2784-2795.
    • (2010) Blood , vol.115 , Issue.14 , pp. 2784-2795
    • Randrianarison-Huetz, V.1    Laurent, B.2    Bardet, V.3    Blobe, G.C.4    Huetz, F.5    Duménil, D.6
  • 41
    • 84887514998 scopus 로고    scopus 로고
    • GFI1B mutation causes a bleeding disorder with abnormal platelet function
    • Stevenson WS, Morel-Kopp MC, Chen Q, et al. GFI1B mutation causes a bleeding disorder with abnormal platelet function. J Thromb Haemost. 2013;11(11):2039-2047.
    • (2013) J Thromb Haemost , vol.11 , Issue.11 , pp. 2039-2047
    • Stevenson, W.S.1    Morel-Kopp, M.C.2    Chen, Q.3
  • 42
    • 84892566252 scopus 로고    scopus 로고
    • A dominant-negative GFI1B mutation in the Gray platelet syndrome
    • Monteferrario D, Bolar NA, Marneth AE, et al. A dominant-negative GFI1B mutation in the Gray platelet syndrome. N Engl J Med. 2014;370(3):245-253.
    • (2014) N Engl J Med , vol.370 , Issue.3 , pp. 245-253
    • Monteferrario, D.1    Bolar, N.A.2    Marneth, A.E.3
  • 43
    • 0027211845 scopus 로고
    • A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins
    • Miller IJ, Bieker JJ. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins. Mol Cell Biol. 1993;13(5):2776-2786. (Pubitemid 23133950)
    • (1993) Molecular and Cellular Biology , vol.13 , Issue.5 , pp. 2776-2786
    • Miller, I.J.1    Bieker, J.J.2
  • 44
    • 84871890500 scopus 로고    scopus 로고
    • EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination
    • Yien YY, Bieker JJ. EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination. Mol Cell Biol. 2013;33(1):4-13.
    • (2013) Mol Cell Biol , vol.33 , Issue.1 , pp. 4-13
    • Yien, Y.Y.1    Bieker, J.J.2
  • 45
    • 0028990264 scopus 로고
    • Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF
    • Perkins AC, Sharpe AH, Orkin SH. Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature. 1995;375(6529):318-322.
    • (1995) Nature , vol.375 , Issue.6529 , pp. 318-322
    • Perkins, A.C.1    Sharpe, A.H.2    Orkin, S.H.3
  • 46
    • 0029010790 scopus 로고
    • Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene
    • Nuez B, Michalovich D, Bygrave A, Ploemacher R, Grosveld F. Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature. 1995;375(6529):316-318.
    • (1995) Nature , vol.375 , Issue.6529 , pp. 316-318
    • Nuez, B.1    Michalovich, D.2    Bygrave, A.3    Ploemacher, R.4    Grosveld, F.5
  • 47
    • 77952632060 scopus 로고    scopus 로고
    • EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation
    • Siatecka M, Lohmann F, Bao S, Bieker JJ. EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation. Mol Cell Biol. 2010;30(11):2811-2822.
    • (2010) Mol Cell Biol , vol.30 , Issue.11 , pp. 2811-2822
    • Siatecka, M.1    Lohmann, F.2    Bao, S.3    Bieker, J.J.4
  • 48
    • 33646675621 scopus 로고    scopus 로고
    • Major erythrocyte membrane protein genes in EKLF-deficient mice
    • DOI 10.1016/j.exphem.2006.02.018, PII S0301472X06001263
    • Nilson DG, Sabatino DE, Bodine DM, Gallagher PG. Major erythrocyte membrane protein genes in EKLF-deficient mice. Exp Hematol. 2006;34(6):705-712. (Pubitemid 43737096)
    • (2006) Experimental Hematology , vol.34 , Issue.6 , pp. 705-712
    • Nilson, D.G.1    Sabatino, D.E.2    Bodine, D.M.3    Gallagher, P.G.4
  • 49
    • 84870543736 scopus 로고    scopus 로고
    • Novel roles for KLF1 in erythropoiesis revealed by mRNA-seq
    • Tallack MR, Magor GW, Dartigues B, et al. Novel roles for KLF1 in erythropoiesis revealed by mRNA-seq. Genome Res. 2012;22(12):2385-2398.
    • (2012) Genome Res , vol.22 , Issue.12 , pp. 2385-2398
    • Tallack, M.R.1    Magor, G.W.2    Dartigues, B.3
  • 50
    • 84863264788 scopus 로고    scopus 로고
    • A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation
    • Wontakal SN, Guo X, Smith C, et al. A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation. Proc Natl Acad Sci U S A. 2012;109(10):3832-3837.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.10 , pp. 3832-3837
    • Wontakal, S.N.1    Guo, X.2    Smith, C.3
  • 51
    • 52649088204 scopus 로고    scopus 로고
    • Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype
    • Singleton BK, Burton NM, Green C, Brady RL, Anstee DJ. Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype. Blood. 2008;112(5):2081-2088.
    • (2008) Blood , vol.112 , Issue.5 , pp. 2081-2088
    • Singleton, B.K.1    Burton, N.M.2    Green, C.3    Brady, R.L.4    Anstee, D.J.5
  • 52
    • 84868191127 scopus 로고    scopus 로고
    • Blood group phenotypes resulting from mutations in erythroid transcription factors
    • Singleton BK, Frayne J, Anstee DJ. Blood group phenotypes resulting from mutations in erythroid transcription factors. Curr Opin Hematol. 2012;19(6):486-493.
    • (2012) Curr Opin Hematol , vol.19 , Issue.6 , pp. 486-493
    • Singleton, B.K.1    Frayne, J.2    Anstee, D.J.3
  • 53
    • 77957016122 scopus 로고    scopus 로고
    • Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor
    • Siatecka M, Sahr KE, Andersen SG, Mezei M, Bieker JJ, Peters LL. Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor. Proc Natl Acad Sci U S A. 2010;107(34):15151- 15156.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.34 , pp. 15151-15156
    • Siatecka, M.1    Sahr, K.E.2    Andersen, S.G.3    Mezei, M.4    Bieker, J.J.5    Peters, L.L.6
  • 54
    • 78649451381 scopus 로고    scopus 로고
    • Mutation in erythroid specific transcription factor KLF1 causes Hereditary Spherocytosis in the Nan hemolytic anemia mouse model
    • Heruth DP, Hawkins T, Logsdon DP, et al. Mutation in erythroid specific transcription factor KLF1 causes Hereditary Spherocytosis in the Nan hemolytic anemia mouse model. Genomics. 2010;96(5):303-307.
    • (2010) Genomics , vol.96 , Issue.5 , pp. 303-307
    • Heruth, D.P.1    Hawkins, T.2    Logsdon, D.P.3
  • 55
    • 8044241134 scopus 로고
    • Dominant haemolytic anaemia
    • Lyon MF. Dominant haemolytic anaemia. Mouse News Lett. 1993;68:68.
    • (1993) Mouse News Lett , vol.68 , pp. 68
    • Lyon, M.F.1
  • 56
    • 78249264453 scopus 로고    scopus 로고
    • A dominant mutation in the gene encoding the erythroid transcription factor KLF1 causes a congenital dyserythropoietic anemia
    • Arnaud L, Saison C, Helias V, et al. A dominant mutation in the gene encoding the erythroid transcription factor KLF1 causes a congenital dyserythropoietic anemia. Am J Hum Genet. 2010;87(5):721-727.
    • (2010) Am J Hum Genet , vol.87 , Issue.5 , pp. 721-727
    • Arnaud, L.1    Saison, C.2    Helias, V.3
  • 57
    • 84897515773 scopus 로고    scopus 로고
    • Mutations in Kruppel-like factor 1 cause transfusion-dependent hemolytic anemia and persistence of embryonic globin gene expression
    • Viprakasit V, Ekwattanakit S, Riolueang S, et al. Mutations in Kruppel-like factor 1 cause transfusion-dependent hemolytic anemia and persistence of embryonic globin gene expression. Blood. 2014;123(10):1586-1595.
    • (2014) Blood , vol.123 , Issue.10 , pp. 1586-1595
    • Viprakasit, V.1    Ekwattanakit, S.2    Riolueang, S.3
  • 58
    • 80052919973 scopus 로고    scopus 로고
    • Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes
    • Singleton BK, Lau W, Fairweather VS, et al. Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes. Blood. 2011;118(11):3137-3145.
    • (2011) Blood , vol.118 , Issue.11 , pp. 3137-3145
    • Singleton, B.K.1    Lau, W.2    Fairweather, V.S.3
  • 60
    • 77956622584 scopus 로고    scopus 로고
    • Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin
    • Borg J, Papadopoulos P, Georgitsi M, et al. Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nat Genet. 2010;42(9):801-805.
    • (2010) Nat Genet , vol.42 , Issue.9 , pp. 801-805
    • Borg, J.1    Papadopoulos, P.2    Georgitsi, M.3
  • 62
    • 50149117726 scopus 로고    scopus 로고
    • DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
    • Lettre G, Sankaran VG, Bezerra MA, et al. DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Proc Natl Acad Sci U S A. 2008;105(33):11869-11874.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.33 , pp. 11869-11874
    • Lettre, G.1    Sankaran, V.G.2    Bezerra, M.A.3
  • 64
    • 57849083996 scopus 로고    scopus 로고
    • Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A
    • Sankaran VG, Menne TF, Xu J, et al. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science. 2008;322(5909):1839-1842.
    • (2008) Science , vol.322 , Issue.5909 , pp. 1839-1842
    • Sankaran, V.G.1    Menne, T.F.2    Xu, J.3
  • 65
    • 69349092063 scopus 로고    scopus 로고
    • Developmental and species-divergent globin switching are driven by BCL11A
    • Sankaran VG, Xu J, Ragoczy T, et al. Developmental and species-divergent globin switching are driven by BCL11A. Nature. 2009;460(7259):1093-1097.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1093-1097
    • Sankaran, V.G.1    Xu, J.2    Ragoczy, T.3
  • 66
    • 77956630402 scopus 로고    scopus 로고
    • KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching
    • Zhou D, Liu K, Sun CW, Pawlik KM, Townes TM. KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching. Nat Genet. 2010;42(9):742-744.
    • (2010) Nat Genet , vol.42 , Issue.9 , pp. 742-744
    • Zhou, D.1    Liu, K.2    Sun, C.W.3    Pawlik, K.M.4    Townes, T.M.5
  • 67
    • 79953117530 scopus 로고    scopus 로고
    • Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer
    • Wilber A, Hargrove PW, Kim YS, et al. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer. Blood. 2011;117(10):2817-2826.
    • (2011) Blood , vol.117 , Issue.10 , pp. 2817-2826
    • Wilber, A.1    Hargrove, P.W.2    Kim, Y.S.3
  • 68
    • 81555205756 scopus 로고    scopus 로고
    • Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing
    • Xu J, Peng C, Sankaran VG, et al. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Science. 2011;334(6058):993-996.
    • (2011) Science , vol.334 , Issue.6058 , pp. 993-996
    • Xu, J.1    Peng, C.2    Sankaran, V.G.3
  • 69
    • 0028858855 scopus 로고
    • Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL
    • Shivdasani RA, Mayer EL, Orkin SH. Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature. 1995;373(6513):432- 434.
    • (1995) Nature , vol.373 , Issue.6513 , pp. 432-434
    • Shivdasani, R.A.1    Mayer, E.L.2    Orkin, S.H.3
  • 70
    • 0029121271 scopus 로고
    • Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene
    • Robb L, Lyons I, Li R, et al. Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. Proc Natl Acad Sci U S A. 1995;92(15):7075-7079.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.15 , pp. 7075-7079
    • Robb, L.1    Lyons, I.2    Li, R.3
  • 71
    • 0037472895 scopus 로고    scopus 로고
    • Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene
    • DOI 10.1038/nature01345
    • Mikkola HK, Klintman J, Yang H, et al. Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature. 2003;421(6922):547-551. (Pubitemid 36168449)
    • (2003) Nature , vol.421 , Issue.6922 , pp. 547-551
    • Mikkola, H.K.A.1    Klintman, J.2    Yang, H.3    Hock, H.4    Schlaeger, T.M.5    Fujiwara, Y.6    Orkin, S.H.7
  • 73
    • 0030999645 scopus 로고    scopus 로고
    • The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins
    • DOI 10.1093/emboj/16.11.3145
    • Wadman IA, Osada H, Grütz GG, et al. The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins. EMBO J. 1997;16(11):3145-3157. (Pubitemid 27234954)
    • (1997) EMBO Journal , vol.16 , Issue.11 , pp. 3145-3157
    • Wadman, I.A.1    Osada, H.2    Grutz, G.G.3    Agulnick, A.D.4    Westphal, H.5    Forster, A.6    Rabbitts, T.H.7
  • 74
    • 35348887715 scopus 로고    scopus 로고
    • Mechanisms of transcription factor deregulation in lymphoid cell transformation
    • DOI 10.1038/sj.onc.1210766, PII 1210766
    • O'Neil J, Look AT. Mechanisms of transcription factor deregulation in lymphoid cell transformation. Oncogene. 2007;26(47):6838-6849. (Pubitemid 47585107)
    • (2007) Oncogene , vol.26 , Issue.47 , pp. 6838-6849
    • O'Neil, J.1    Look, A.T.2
  • 75
    • 84863649033 scopus 로고    scopus 로고
    • Master regulatory GATA transcription factors: Mechanistic principles and emerging links to hematologic malignancies
    • Bresnick EH, Katsumura KR, Lee HY, Johnson KD, Perkins AS. Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res. 2012;40(13):5819-5831.
    • (2012) Nucleic Acids Res , vol.40 , Issue.13 , pp. 5819-5831
    • Bresnick, E.H.1    Katsumura, K.R.2    Lee, H.Y.3    Johnson, K.D.4    Perkins, A.S.5
  • 79
    • 80053383273 scopus 로고    scopus 로고
    • Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia
    • Hahn CN, Chong CE, Carmichael CL, et al. Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nat Genet. 2011;43(10):1012-1017.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 1012-1017
    • Hahn, C.N.1    Chong, C.E.2    Carmichael, C.L.3
  • 80
    • 79961074298 scopus 로고    scopus 로고
    • Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
    • Hsu AP, Sampaio EP, Khan J, et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. Blood. 2011;118(10):2653-2655.
    • (2011) Blood , vol.118 , Issue.10 , pp. 2653-2655
    • Hsu, A.P.1    Sampaio, E.P.2    Khan, J.3
  • 81
    • 80053385569 scopus 로고    scopus 로고
    • Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
    • Ostergaard P, Simpson MA, Connell FC, et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). Nat Genet. 2011;43(10):929-931.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 929-931
    • Ostergaard, P.1    Simpson, M.A.2    Connell, F.C.3
  • 82
    • 0027264128 scopus 로고
    • Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner
    • Briegel K, Lim KC, Plank C, Beug H, Engel JD, Zenke M. Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. Genes Dev. 1993;7(6):1097-1109. (Pubitemid 23170832)
    • (1993) Genes and Development , vol.7 , Issue.6 , pp. 1097-1109
    • Briegel, K.1    Lim, K.-C.2    Plank, C.3    Beug, H.4    Engel, J.D.5    Zenke, M.6
  • 83
    • 0033565812 scopus 로고    scopus 로고
    • A GATA-2/estrogen receptor chimera functions as a ligand-dependent negative regulator of self-renewal
    • Heyworth C, Gale K, Dexter M, May G, Enver TA. A GATA-2/estrogen receptor chimera functions as a ligand-dependent negative regulator of self-renewal. Genes Dev. 1999;13(14):1847-1860. (Pubitemid 29353051)
    • (1999) Genes and Development , vol.13 , Issue.14 , pp. 1847-1860
    • Heyworth, C.1    Gale, K.2    Dexter, M.3    May, G.4    Enver, T.5
  • 85
    • 78049432269 scopus 로고    scopus 로고
    • A single cis element maintains repression of the key developmental regulator Gata2
    • Snow JW, Trowbridge JJ, Fujiwara T, et al. A single cis element maintains repression of the key developmental regulator Gata2. PLoS Genet. 2010;6(9):e1001103.
    • (2010) PLoS Genet , vol.6 , Issue.9
    • Snow, J.W.1    Trowbridge, J.J.2    Fujiwara, T.3
  • 86
    • 84867280730 scopus 로고    scopus 로고
    • Combinatorial regulation of tissue specification by GATA and FOG factors
    • Chlon TM, Crispino JD. Combinatorial regulation of tissue specification by GATA and FOG factors. Development. 2012;139(21):3905-3916.
    • (2012) Development , vol.139 , Issue.21 , pp. 3905-3916
    • Chlon, T.M.1    Crispino, J.D.2
  • 87
    • 0032522474 scopus 로고    scopus 로고
    • Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
    • Tsang AP, Fujiwara Y, Hom DB, Orkin SH. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes Dev. 1998;12(8):1176-1188. (Pubitemid 28194053)
    • (1998) Genes and Development , vol.12 , Issue.8 , pp. 1176-1188
    • Tsang, A.P.1    Fujiwara, Y.2    Horn, D.B.3    Orkin, S.H.4
  • 89
    • 84891159436 scopus 로고    scopus 로고
    • Ldb1 complexes: The new master regulators of erythroid gene transcription
    • Love PE, Warzecha C, Li L. Ldb1 complexes: the new master regulators of erythroid gene transcription. Trends Genet. 2014;30(1):1-9.
    • (2014) Trends Genet , vol.30 , Issue.1 , pp. 1-9
    • Love, P.E.1    Warzecha, C.2    Li, L.3
  • 90
    • 0027243681 scopus 로고
    • Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein
    • DOI 10.1038/362722a0
    • Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, Orkin SH. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature. 1993;362(6422):722-728. (Pubitemid 23125974)
    • (1993) Nature , vol.362 , Issue.6422 , pp. 722-728
    • Andrews, N.C.1    Erdjument-Bromage, H.2    Davidson, M.B.3    Tempst, P.4    Orkin, S.H.5
  • 91
    • 0032037890 scopus 로고    scopus 로고
    • The NF-E2 transcription factor
    • Andrews NC. The NF-E2 transcription factor. Int J Biochem Cell Biol. 1998;30(4):429-432.
    • (1998) Int J Biochem Cell Biol , vol.30 , Issue.4 , pp. 429-432
    • Andrews, N.C.1
  • 93
    • 84876511310 scopus 로고    scopus 로고
    • Elevated nuclear factor erythroid-2 levels promote epo-independent erythroid maturation and recapitulate the hematopoietic stem cell and common myeloid progenitor expansion observed in polycythemia vera patients
    • Bogeska R, Pahl HL. Elevated nuclear factor erythroid-2 levels promote epo-independent erythroid maturation and recapitulate the hematopoietic stem cell and common myeloid progenitor expansion observed in polycythemia vera patients. Stem Cells Transl Med. 2013;2(2):112-117.
    • (2013) Stem Cells Transl Med , vol.2 , Issue.2 , pp. 112-117
    • Bogeska, R.1    Pahl, H.L.2
  • 94
    • 84856911269 scopus 로고    scopus 로고
    • A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2
    • Kaufmann KB, Gründer A, Hadlich T, et al. A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2. J Exp Med. 2012;209(1):35-50.
    • (2012) J Exp Med , vol.209 , Issue.1 , pp. 35-50
    • Kaufmann, K.B.1    Gründer, A.2    Hadlich, T.3
  • 95
    • 84879557768 scopus 로고    scopus 로고
    • MPN patients harbor recurrent truncating mutations in transcription factor NF-E2
    • Jutzi JS, Bogeska R, Nikoloski G, et al. MPN patients harbor recurrent truncating mutations in transcription factor NF-E2. J Exp Med. 2013;210(5):1003-1019.
    • (2013) J Exp Med , vol.210 , Issue.5 , pp. 1003-1019
    • Jutzi, J.S.1    Bogeska, R.2    Nikoloski, G.3
  • 96
    • 0029051295 scopus 로고
    • Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development
    • Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, et al. Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell. 1995;81(5):695-704.
    • (1995) Cell , vol.81 , Issue.5 , pp. 695-704
    • Shivdasani, R.A.1    Rosenblatt, M.F.2    Zucker-Franklin, D.3
  • 97
    • 0029050860 scopus 로고
    • Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2
    • Shivdasani RA, Orkin SH. Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc Natl Acad Sci U S A. 1995;92(19):8690-8694.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.19 , pp. 8690-8694
    • Shivdasani, R.A.1    Orkin, S.H.2
  • 99
    • 68149162593 scopus 로고    scopus 로고
    • Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II
    • Schwarz K, Iolascon A, Verissimo F, et al. Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II. Nat Genet. 2009;41(8):936-940.
    • (2009) Nat Genet , vol.41 , Issue.8 , pp. 936-940
    • Schwarz, K.1    Iolascon, A.2    Verissimo, F.3
  • 100
    • 84863957813 scopus 로고    scopus 로고
    • SEC23B is required for the maintenance of murine professional secretory tissues
    • Tao J, Zhu M, Wang H, et al. SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012;109(29):E2001-E2009.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.29
    • Tao, J.1    Zhu, M.2    Wang, H.3
  • 101
    • 47249142778 scopus 로고    scopus 로고
    • Revealing the architecture of gene regulation: The promise of eQTL studies
    • Gilad Y, Rifkin SA, Pritchard JK. Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet. 2008;24(8):408-415.
    • (2008) Trends Genet , vol.24 , Issue.8 , pp. 408-415
    • Gilad, Y.1    Rifkin, S.A.2    Pritchard, J.K.3
  • 102
    • 84871464519 scopus 로고    scopus 로고
    • Seventy-five genetic loci influencing the human red blood cell
    • van der Harst P, Zhang W, Mateo Leach I, et al. Seventy-five genetic loci influencing the human red blood cell. Nature. 2012;492(7429):369-375.
    • (2012) Nature , vol.492 , Issue.7429 , pp. 369-375
    • Van Der Harst, P.1    Zhang, W.2    Mateo Leach, I.3
  • 103
    • 65349107708 scopus 로고    scopus 로고
    • Discovering the genetics underlying foetal haemoglobin production in adults
    • Thein SL, Menzel S. Discovering the genetics underlying foetal haemoglobin production in adults. Br J Haematol. 2009;145(4):455-467.
    • (2009) Br J Haematol , vol.145 , Issue.4 , pp. 455-467
    • Thein, S.L.1    Menzel, S.2
  • 104
    • 84885620722 scopus 로고    scopus 로고
    • An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
    • Bauer DE, Kamran SC, Lessard S, et al. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science. 2013;342(6155):253-257.
    • (2013) Science , vol.342 , Issue.6155 , pp. 253-257
    • Bauer, D.E.1    Kamran, S.C.2    Lessard, S.3
  • 105
    • 84879264708 scopus 로고    scopus 로고
    • ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
    • Gaj T, Gersbach CA, Barbas CF III. ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol. 2013;31(7):397-405.
    • (2013) Trends Biotechnol , vol.31 , Issue.7 , pp. 397-405
    • Gaj, T.1    Gersbach, C.A.2    Barbas III, C.F.3
  • 106
    • 84866600774 scopus 로고    scopus 로고
    • Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number
    • Sankaran VG, Ludwig LS, Sicinska E, et al. Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev. 2012;26(18):2075-2087.
    • (2012) Genes Dev , vol.26 , Issue.18 , pp. 2075-2087
    • Sankaran, V.G.1    Ludwig, L.S.2    Sicinska, E.3
  • 107
    • 84892507301 scopus 로고    scopus 로고
    • Applications of high-throughput DNA sequencing to benign hematology
    • Sankaran VG, Gallagher PG. Applications of high-throughput DNA sequencing to benign hematology. Blood. 2013;122(22):3575-3582.
    • (2013) Blood , vol.122 , Issue.22 , pp. 3575-3582
    • Sankaran, V.G.1    Gallagher, P.G.2
  • 108
    • 84877707375 scopus 로고    scopus 로고
    • One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
    • Wang H, Yang H, Shivalila CS, et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell. 2013;153(4):910-918.
    • (2013) Cell , vol.153 , Issue.4 , pp. 910-918
    • Wang, H.1    Yang, H.2    Shivalila, C.S.3
  • 109
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium
    • Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M; ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489(7414):57-74.
    • (2012) Nature , vol.489 , Issue.7414 , pp. 57-74
    • Bernstein, B.E.1    Birney, E.2    Dunham, I.3    Green, E.D.4    Gunter, C.5    Snyder, M.6
  • 110
    • 79955550445 scopus 로고    scopus 로고
    • A user's guide to the encyclopedia of DNA elements (ENCODE)
    • ENCODE Project Consortium
    • Consortium EP; ENCODE Project Consortium. A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 2011;9(4):e1001046.
    • (2011) PLoS Biol , vol.9 , Issue.4
    • Consortium, E.P.1
  • 111
    • 84890502397 scopus 로고    scopus 로고
    • Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps
    • Mortazavi A, Pepke S, Jansen C, et al. Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps. Genome Res. 2013;23(12):2136-2148.
    • (2013) Genome Res , vol.23 , Issue.12 , pp. 2136-2148
    • Mortazavi, A.1    Pepke, S.2    Jansen, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.