Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes

Blood

Volumn 118, Issue 11, 2011, Pages 3137-3145

  Singleton, Belinda K ^a   Lau, Winnie ^b   Fairweather, Victoria S S ^b   Burton, Nicholas M ^b   Wilson, Marieangela C ^b   Parsons, Steve F ^a   Richardson, Ben M ^b   Trakarnsanga, Kongtana ^b   Brady, R Leo ^b   Anstee, David J ^a   Frayne, Jan ^b  

^a NHS BLOOD AND TRANSPLANT   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; ERYTHROID KRUPPEL LIKE FACTOR;

ANEMIA; ARTICLE; BINDING AFFINITY; DNA BINDING; FRAMESHIFT MUTATION; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONSENSE MUTATION; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; ZINC FINGER MOTIF;

EID: 80052919973     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-04-349985     Document Type: Article

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